| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Theodoros Tsetsenis, Julia K Badyna, Julianne A Wilson, Xiaowen Zhang, Elizabeth N Krizman, Manivannan Subramaniyan, Kechun Yang, Steven A Thomas, John A Dan. Midbrain dopaminergic innervation of the hippocampus is sufficient to modulate formation of aversive memories. Proceedings of the National Academy of Sciences of the United States of America. vol 118. issue 40. 2021-12-06. PMID:34580198. |
we identify a population of midbrain dopaminergic neurons near the border of the substantia nigra pars compacta and the lateral ventral tegmental area that sends direct projections to the dorsal hippocampus. |
2021-12-06 |
2023-08-13 |
mouse |
| A Ilari, L Curti, M Petrella, N Cannella, A La Rocca, G Ranieri, E Gerace, D Iezzi, L Silvestri, G Mannaioni, R Ciccocioppo, A Mas. Moderate ethanol drinking is sufficient to alter Ventral Tegmental Area dopamine neurons activity via functional and structural remodeling of GABAergic transmission. Neuropharmacology. vol 203. 2021-12-03. PMID:34785165. |
by recording from da and γ-aminobutyric acid (gaba) vta neurons in midbrain slices, we found that moderate etoh drinking leads to a significant suppression of the spontaneous activity of vta da neurons, while increasing their response to acute etoh application. |
2021-12-03 |
2023-08-13 |
mouse |
| Sjoerd R Murris, John T Arsenault, Wim Vanduffe. Frequency- and State-Dependent Network Effects of Electrical Stimulation Targeting the Ventral Tegmental Area in Macaques. Cerebral cortex (New York, N.Y. : 1991). vol 30. issue 8. 2021-11-29. PMID:32279076. |
the ventral tegmental area (vta) is a midbrain structure at the heart of the dopaminergic system underlying adaptive behavior. |
2021-11-29 |
2023-08-13 |
monkey |
| Ke Xu, Jia Guo, Mingyue Ge, Jiangwen Yin, Han Zhang, Jieting Yin, Yan L. Effects of dopamine transporter changes in the ventral tegmental area of the midbrain on cognitive function in aged rats. Journal of chemical neuroanatomy. vol 117. 2021-11-26. PMID:34329711. |
therefore, the purpose of this study was to investigate the relationship between changes in dopamine transporters in the ventral tegmental area (vta) of the midbrain and postoperative cognitive dysfunction in elderly rats. |
2021-11-26 |
2023-08-13 |
rat |
| Lindsey N Friend, Bridget Wu, Jeffrey G Edward. Acute cocaine exposure occludes long-term depression in ventral tegmental area GABA neurons. Neurochemistry international. vol 145. 2021-11-18. PMID:33617930. |
the ventral tegmental area (vta) in the midbrain is essential in incentive salience of reward behavior. |
2021-11-18 |
2023-08-13 |
mouse |
| Lindsey N Friend, Bridget Wu, Jeffrey G Edward. Acute cocaine exposure occludes long-term depression in ventral tegmental area GABA neurons. Neurochemistry international. vol 145. 2021-11-18. PMID:33617930. |
drugs of abuse increase midbrain dopamine cell activity and/or dopamine levels, and can alter endogenous vta glutamate plasticity, leading to addiction or dependence. |
2021-11-18 |
2023-08-13 |
mouse |
| Véronne A J de Vrind, Lisanne J van 't Sant, Annemieke Rozeboom, Mieneke C M Luijendijk-Berg, Azar Omrani, Roger A H Ada. Leptin Receptor Expressing Neurons in the Substantia Nigra Regulate Locomotion, and in The Ventral Tegmental Area Motivation and Feeding. Frontiers in endocrinology. vol 12. 2021-11-18. PMID:34276560. |
in most studies that target the midbrain, either all lepr neurons of the midbrain or those of the ventral tegmental area (vta) were targeted, but the role of substantia nigra (sn) lepr neurons has not been investigated. |
2021-11-18 |
2023-08-13 |
mouse |
| Véronne A J de Vrind, Lisanne J van 't Sant, Annemieke Rozeboom, Mieneke C M Luijendijk-Berg, Azar Omrani, Roger A H Ada. Leptin Receptor Expressing Neurons in the Substantia Nigra Regulate Locomotion, and in The Ventral Tegmental Area Motivation and Feeding. Frontiers in endocrinology. vol 12. 2021-11-18. PMID:34276560. |
since not all midbrain lepr mediated behaviors can be explained by lepr neurons in the vta alone, we hypothesized that sn lepr neurons may provide further insight. |
2021-11-18 |
2023-08-13 |
mouse |
| Véronne A J de Vrind, Lisanne J van 't Sant, Annemieke Rozeboom, Mieneke C M Luijendijk-Berg, Azar Omrani, Roger A H Ada. Leptin Receptor Expressing Neurons in the Substantia Nigra Regulate Locomotion, and in The Ventral Tegmental Area Motivation and Feeding. Frontiers in endocrinology. vol 12. 2021-11-18. PMID:34276560. |
to further understand the role of midbrain lepr neurons in body weight regulation, we chemogenetically activated vta lepr or sn lepr neurons in lepr-cre mice and tested for motivational behavior, feeding and locomotion. |
2021-11-18 |
2023-08-13 |
mouse |
| Feng He, Pei Zhang, Qian Zhang, Guangjian Qi, Hongwei Cai, Tongxia Li, Ming Li, Jiazhen Lu, Jiaen Lin, Jie Ming, Bo Tia. Dopaminergic Projection from Ventral Tegmental Area to Substantia Nigra Pars Reticulata Mediates Chronic Social Defeat Stress-Induced Hypolocomotion. Molecular neurobiology. vol 58. issue 11. 2021-11-18. PMID:34382160. |
in mdd, the midbrain ventral tegmental area (vta) dopamine (da) neurons are closely related to regulate the information processing of reward, motivation, cognition, and aversion. |
2021-11-18 |
2023-08-13 |
mouse |
| Thomas C Jho. The rostromedial tegmental (RMTg) "brake" on dopamine and behavior: A decade of progress but also much unfinished work. Neuropharmacology. vol 198. 2021-11-17. PMID:34433088. |
between 2005 and 2009, several research groups identified a strikingly dense inhibitory input to midbrain dopamine neurons arising from a previously uncharted region posterior to the ventral tegmental area (vta). |
2021-11-17 |
2023-08-13 |
Not clear |
| Ludi Zhang, Jing Wang, Chenxu Niu, Yu Zhang, Tiantian Zhu, Dongyang Huang, Jing Ma, Hui Sun, Nikita Gamper, Xiaona Du, Hailin Zhan. Activation of parabrachial nucleus - ventral tegmental area pathway underlies the comorbid depression in chronic neuropathic pain in mice. Cell reports. vol 37. issue 5. 2021-11-17. PMID:34731609. |
in parallel, we observe increased activity of the dopaminergic (da) neuron in the midbrain ventral tegmental area (vta), and inhibition of this elevated vta da neuron activity reverses the behavioral manifestations of depression. |
2021-11-17 |
2023-08-13 |
mouse |
| Aqilah M McCane, Meredyth A Wegener, Mojdeh Faraji, Maria T Rivera-Garcia, Kathryn G Wallin-Miller, Vincent D Costa, Bita Moghadda. Adolescent Dopamine Neurons Represent Reward Differently during Action and State Guided Learning. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 45. 2021-11-14. PMID:34611024. |
both forms of learning, when associated with a rewarding outcome, rely on midbrain dopamine neurons in the ventral tegmental area (vta) and substantia nigra (sn). |
2021-11-14 |
2023-08-13 |
rat |
| Seong W Kan. Central Nervous System Associated With Light Perception and Physiological Responses of Birds. Frontiers in physiology. vol 12. 2021-11-10. PMID:34744764. |
although further research is required to establish the functional role of opn4 in the ventral tegmental area (vta), dorsal raphe nucleus, and caudal raphe nucleus in the light perception and physiological responses of birds, it is an exciting prospect because the previous results in birds support this hypothesis that opn4 in the midbrain da and serotonin neurons may play significant roles on the light-induced welfare of birds. |
2021-11-10 |
2023-08-13 |
Not clear |
| Steve Seo, Rachel J Sizemore, Karen L Reader, Roseanna A Smither, Hollie E Wicky, Stephanie M Hughes, David K Bilkey, Louise C Parr-Brownlie, Dorothy E Oorscho. A schizophrenia risk factor induces marked anatomical deficits at GABAergic-dopaminergic synapses in the rat ventral tegmental area: Essential evidence for new targeted therapies. The Journal of comparative neurology. vol 529. issue 18. 2021-11-09. PMID:34338311. |
using a novel combination of lentiviruses, peroxidase-immunogold double labeling, three-dimensional serial section transmission electron microscopy and stereology, we observed clear anatomical alterations in synaptic inputs on dopaminergic neurons in the midbrain posterior ventral tegmental area (pvta). |
2021-11-09 |
2023-08-13 |
rat |
| K Ushna S Islam, Norisa Meli, Sandra Blaes. The Development of the Mesoprefrontal Dopaminergic System in Health and Disease. Frontiers in neural circuits. vol 15. 2021-10-30. PMID:34712123. |
midbrain dopaminergic neurons located in the substantia nigra and the ventral tegmental area are the main source of dopamine in the brain. |
2021-10-30 |
2023-08-13 |
Not clear |
| Heather N Lavezzi, Daniel S Zah. The mesopontine rostromedial tegmental nucleus: an integrative modulator of the reward system. Basal ganglia. vol 1. issue 4. 2021-10-21. PMID:22163100. |
the rmtg is prominently gabaergic, receives dense projections from the lateral habenula and projects strongly to the midbrain ventral tegmental area and substantia nigra compacta. |
2021-10-21 |
2023-08-12 |
Not clear |
| Mikhail U Inyushin, Francisco Arencibia-Albite, Angel de la Cruz, Rafael Vázquez-Torres, Katiria Colon, Priscila Sanabria, Carlos A Jiménez-River. New method to visualize neurons with DAT in slices of rat VTA using fluorescent substrate for DAT, ASP+ Journal of neuroscience and neuroengineering. vol 2. issue 2. 2021-10-21. PMID:24052926. |
new method to visualize neurons with dat in slices of rat vta using fluorescent substrate for dat, asp+ the ventral tegmental area (vta), and in particular dopamine (da) neurons in this region of midbrain, has been shown to play an important role in motivation (goal-directed behavior), reward, and drug addiction. |
2021-10-21 |
2023-08-12 |
rat |
| Muhammad Zubair, Sjoerd R Murris, Kaoru Isa, Hirotaka Onoe, Yoshinori Koshimizu, Kenta Kobayashi, Wim Vanduffel, Tadashi Is. Divergent Whole Brain Projections from the Ventral Midbrain in Macaques. Cerebral cortex (New York, N.Y. : 1991). vol 31. issue 6. 2021-10-11. PMID:33558867. |
to understand the connectome of the axonal arborizations of dopaminergic midbrain neurons, we investigated the anterograde spread of highly sensitive viral tracers injected into the ventral tegmental area (vta) and adjacent areas in 3 macaques. |
2021-10-11 |
2023-08-13 |
monkey |
| Saad Latif, Muhammad Jahangeer, Dure Maknoon Razia, Mehvish Ashiq, Abdul Ghaffar, Muhammad Akram, Aicha El Allam, Abdelhakim Bouyahya, Larisa Garipova, Mohammad Ali Shariati, Muthu Thiruvengadam, Mohammad Azam Ansar. Dopamine in Parkinson's disease. Clinica chimica acta; international journal of clinical chemistry. vol 522. 2021-09-28. PMID:34389279. |
the production of dopamine (a monoamine neurotransmitter) occurs in the ventral tegmental area (vta) of the substantia nigra, specifically in the hypothalamic nucleus and midbrain. |
2021-09-28 |
2023-08-13 |
Not clear |