| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pedro Rifes, Marc Isaksson, Charlotte Rusimbi, Adrián Ramón Santonja, Jenny Nelander, Thomas Laurell, Agnete Kirkeb. Identifying secreted biomarkers of dopaminergic ventral midbrain progenitor cells. Stem cell research & therapy. vol 14. issue 1. 2023-12-10. PMID:38072935. |
ventral midbrain (vm) dopaminergic progenitor cells derived from human pluripotent stem cells have the potential to replace endogenously lost dopamine neurons and are currently in preclinical and clinical development for treatment of parkinson's disease (pd). |
2023-12-10 |
2023-12-17 |
human |
| Niklas Hammer, Pascal Vogel, Sanghun Lee, Jochen Roepe. Optogenetic action potentials and intrinsic pacemaker interplay in retrogradely identified midbrain dopamine neurons. The European journal of neuroscience. 2023-12-06. PMID:38056070. |
optogenetic action potentials and intrinsic pacemaker interplay in retrogradely identified midbrain dopamine neurons. |
2023-12-06 |
2023-12-10 |
mouse |
| Niklas Hammer, Pascal Vogel, Sanghun Lee, Jochen Roepe. Optogenetic action potentials and intrinsic pacemaker interplay in retrogradely identified midbrain dopamine neurons. The European journal of neuroscience. 2023-12-06. PMID:38056070. |
dissecting the diversity of midbrain dopamine (da) neurons by optotagging is a promising addition to better identify their functional properties and contribution to motivated behavior. |
2023-12-06 |
2023-12-10 |
mouse |
| Malika S Datta, Yannan Chen, Shradha Chauhan, Jing Zhang, Estanislao Daniel De La Cruz, Cheng Gong, Raju Tome. Whole-brain mapping reveals the divergent impact of ketamine on the dopamine system. Cell reports. 2023-12-05. PMID:38052211. |
here, we develop a sub-cellular resolution whole-brain phenotyping approach and utilize it in male mice to show that repeated ketamine administration leads to a dose-dependent decrease in dopamine neurons in midbrain regions linked to behavioral states, alongside an increase in the hypothalamus. |
2023-12-05 |
2023-12-10 |
mouse |
| Francis Carter, Marie-Pierre Cossette, Ivan Trujillo-Pisanty, Vasilios Pallikaras, Yannick-André Breton, Kent Conover, Jill Caplan, Pavel Solis, Jacques Voisard, Alexandra Yaksich, Peter Shizga. Does phasic dopamine release cause policy updates? The European journal of neuroscience. 2023-12-01. PMID:38039083. |
here, we challenge this view by demonstrating stable, non-maximal work rates in the face of repeated optogenetic stimulation of midbrain dopamine neurons. |
2023-12-01 |
2023-12-10 |
rat |
| L Paul Sands, Angela Jiang, Brittany Liebenow, Emily DiMarco, Adrian W Laxton, Stephen B Tatter, P Read Montague, Kenneth T Kishid. Subsecond fluctuations in extracellular dopamine encode reward and punishment prediction errors in humans. Science advances. vol 9. issue 48. 2023-12-01. PMID:38039368. |
in the mammalian brain, midbrain dopamine neuron activity is hypothesized to encode reward prediction errors that promote learning and guide behavior by causing rapid changes in dopamine levels in target brain regions. |
2023-12-01 |
2023-12-10 |
human |
| Dana Bell, Vaughn J Waldron, P Leon Brow. Quantitative and qualitative sex difference in habenula-induced inhibition of midbrain dopamine neurons in the rat. Frontiers in behavioral neuroscience. vol 17. 2023-12-01. PMID:38025387. |
quantitative and qualitative sex difference in habenula-induced inhibition of midbrain dopamine neurons in the rat. |
2023-12-01 |
2023-12-07 |
rat |
| Dana Bell, Vaughn J Waldron, P Leon Brow. Quantitative and qualitative sex difference in habenula-induced inhibition of midbrain dopamine neurons in the rat. Frontiers in behavioral neuroscience. vol 17. 2023-12-01. PMID:38025387. |
midbrain dopamine neurons are implicated in several of these same disorders and consequently are under investigation for their potential role in the manifestation of these sex differences. |
2023-12-01 |
2023-12-07 |
rat |
| Dana Bell, Vaughn J Waldron, P Leon Brow. Quantitative and qualitative sex difference in habenula-induced inhibition of midbrain dopamine neurons in the rat. Frontiers in behavioral neuroscience. vol 17. 2023-12-01. PMID:38025387. |
quantitative and qualitative sex difference in habenula-induced inhibition of midbrain dopamine neurons in the rat. |
2023-11-29 |
2023-12-07 |
rat |
| Dana Bell, Vaughn J Waldron, P Leon Brow. Quantitative and qualitative sex difference in habenula-induced inhibition of midbrain dopamine neurons in the rat. Frontiers in behavioral neuroscience. vol 17. 2023-12-01. PMID:38025387. |
midbrain dopamine neurons are implicated in several of these same disorders and consequently are under investigation for their potential role in the manifestation of these sex differences. |
2023-11-29 |
2023-12-07 |
rat |
| Harris E Blankenship, Kelsey A Carter, Nina T Cassidy, Andrea N Markiewicz, Michael I Thellmann, Amanda L Sharpe, Willard M Freeman, Michael J Beckstea. VTA dopamine neurons are hyperexcitable in 3xTg-AD mice due to casein kinase 2-dependent SK channel dysfunction. bioRxiv : the preprint server for biology. 2023-11-28. PMID:38014232. |
here, we investigated the role of midbrain dopamine (da) neurons in ad using the amyloid + tau-driven 3xtg-ad mouse model. |
2023-11-28 |
2023-11-29 |
mouse |
| Dmitrii S Traktirov, Ilya R Nazarov, Valeria S Artemova, Raul R Gainetdinov, Nina S Pestereva, Marina N Karpenk. Alterations in Serotonin Neurotransmission in Hyperdopaminergic Rats Lacking the Dopamine Transporter. Biomedicines. vol 11. issue 11. 2023-11-25. PMID:38001881. |
in this article we showed that knockout of the gene encoding dat leads not only to a profound dysregulation of dopamine neurotransmission in the striatum but also in the midbrain, prefrontal cortex, hippocampus, medulla oblongata and spinal cord. |
2023-11-25 |
2023-11-28 |
rat |
| Koji Ishikuro, Noriaki Hattori, Hironori Otomune, Kohta Furuya, Takeshi Nakada, Kenichiro Miyahara, Takashi Shibata, Kyo Noguchi, Satoshi Kuroda, Yuji Nakatsuji, Hisao Nishij. Neural Mechanisms of Neuro-Rehabilitation Using Transcranial Direct Current Stimulation (tDCS) over the Front-Polar Area. Brain sciences. vol 13. issue 11. 2023-11-25. PMID:38002563. |
we argue that the application of tdcs to the fpa promotes motor skill learning through its effects on the m1 area and midbrain dopamine neurons. |
2023-11-25 |
2023-11-28 |
human |
| Miguel Á Luján, Dan P Covey, Reana Young-Morrison, LanYuan Zhang, Andrew Kim, Fiorella Morgado, Sachin Patel, Caroline E Bass, Carlos Paladini, Joseph F Chee. Mobilization of endocannabinoids by midbrain dopamine neurons is required for the encoding of reward prediction. Nature communications. vol 14. issue 1. 2023-11-24. PMID:37985770. |
mobilization of endocannabinoids by midbrain dopamine neurons is required for the encoding of reward prediction. |
2023-11-24 |
2023-11-28 |
mouse |
| Miguel Á Luján, Dan P Covey, Reana Young-Morrison, LanYuan Zhang, Andrew Kim, Fiorella Morgado, Sachin Patel, Caroline E Bass, Carlos Paladini, Joseph F Chee. Mobilization of endocannabinoids by midbrain dopamine neurons is required for the encoding of reward prediction. Nature communications. vol 14. issue 1. 2023-11-24. PMID:37985770. |
however, it is not clear whether mobilization of 2-ag specifically from midbrain dopamine neurons is necessary for dopaminergic responses to external stimuli predicting forthcoming reward. |
2023-11-24 |
2023-11-28 |
mouse |
| Ryunosuke Amo, Naoshige Uchida, Mitsuko Watabe-Uchid. Glutamate inputs send prediction error of reward but not negative value of aversive stimuli to dopamine neurons. bioRxiv : the preprint server for biology. 2023-11-21. PMID:37986868. |
midbrain dopamine neurons are thought to signal reward prediction errors (rpes) but the mechanisms underlying rpe computation, particularly contributions of different neurotransmitters, remain poorly understood. |
2023-11-21 |
2023-11-29 |
Not clear |
| Hye Yun Kim, Jieun Lee, Hyun-Jin Kim, Byeong Eun Lee, Jaewook Jeong, Eun Jeong Cho, Hyun-Jun Jang, Kyeong Jin Shin, Min Ji Kim, Young Chan Chae, Seung Eun Lee, Kyungjae Myung, Ja-Hyun Baik, Pann-Ghill Suh, Jae-Ick Ki. PLCγ1 in dopamine neurons critically regulates striatal dopamine release via VMAT2 and synapsin III. Experimental & molecular medicine. 2023-11-01. PMID:37907739. |
we found that cell type-specific deletion of plcγ1 does not adversely affect the development and cellular morphology of midbrain dopamine neurons but does facilitate dopamine release from dopaminergic axon terminals in the striatum. |
2023-11-01 |
2023-11-08 |
mouse |
| Yun-Feng Zhang, Jialiang Wu, Yingqi Wang, Natalie L Johnson, Janardhan P Bhattarai, Guanqing Li, Wenqiang Wang, Camilo Guevara, Hannah Shoenhard, Marc V Fuccillo, Daniel W Wesson, Minghong M. Ventral striatal islands of Calleja neurons bidirectionally mediate depression-like behaviors in mice. Nature communications. vol 14. issue 1. 2023-10-30. PMID:37898623. |
finally, we propose a model that explains how ot d3 neurons may influence dopamine release via synaptic connections with ot spiny projection neurons (spns) that project to midbrain dopamine neurons. |
2023-10-30 |
2023-11-08 |
mouse |
| Daniel L Albaugh, Aryn H Gitti. Basal ganglia: Appreciating the 'value' of the GPe. Current biology : CB. vol 33. issue 20. 2023-10-26. PMID:37875082. |
a newly discovered cell type, the slow pacemaker, robustly encodes reward value and generates prediction errors in a manner remarkably similar to midbrain dopamine neurons. |
2023-10-26 |
2023-11-08 |
Not clear |
| Alice Petty, Anna Garcia-Hidalgo, Els F Halff, Sridhar Natesan, Dominic J Withers, Elaine E Irvine, Michelle Kokkinou, Lisa A Wells, David R Bonsall, Sac-Pham Tang, Mattia Veronese, Oliver D Howe. Sub-Chronic Ketamine Administration Increases Dopamine Synthesis Capacity in the Mouse Midbrain: a Preclinical In Vivo PET Study. Molecular imaging and biology. 2023-10-23. PMID:37872462. |
sub-chronic ketamine administration increases dopamine synthesis capacity in the mouse midbrain: a preclinical in vivo pet study. |
2023-10-23 |
2023-11-08 |
mouse |