| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Li-Min Mao, Henry H Wang, John Q Wan. Antagonism of Muscarinic Acetylcholine Receptors Alters Synaptic ERK Phosphorylation in the Rat Forebrain. Neurochemical research. vol 42. issue 4. 2017-08-04. PMID:28032295. |
we found that a systemic injection of the machr antagonist scopolamine increased phosphorylation of synaptic erks in the striatum (caudate putamen and nucleus accumbens) and medial prefrontal cortex (mpfc). |
2017-08-04 |
2023-08-13 |
human |
| Colby R Keistler, Emma Hammarlund, Jacqueline M Barker, Colin W Bond, Ralph J DiLeone, Christopher Pittenger, Jane R Taylo. Regulation of Alcohol Extinction and Cue-Induced Reinstatement by Specific Projections among Medial Prefrontal Cortex, Nucleus Accumbens, and Basolateral Amygdala. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 37. issue 17. 2017-07-31. PMID:28336571. |
previous studies have demonstrated that the regulation of cue-guided alcohol seeking is mediated by the basolateral amygdala (bla), nucleus accumbens (nac), and medial prefrontal cortex (mpfc). |
2017-07-31 |
2023-08-13 |
rat |
| Amanda A Braun, Robyn M Amos-Kroohs, Arnold Gutierrez, Kerstin H Lundgren, Kim B Seroogy, Charles V Vorhees, Michael T William. 6-Hydroxydopamine-Induced Dopamine Reductions in the Nucleus Accumbens, but not the Medial Prefrontal Cortex, Impair Cincinnati Water Maze Egocentric and Morris Water Maze Allocentric Navigation in Male Sprague-Dawley Rats. Neurotoxicity research. vol 30. issue 2. 2017-07-17. PMID:27003940. |
the nucleus accumbens (nacc) and medial prefrontal cortex (mpfc) receive dopaminergic innervation from the ventral tegmental area and are involved in learning. |
2017-07-17 |
2023-08-13 |
rat |
| Ellen M McGlinchey, Morgan H James, Stephen V Mahler, Caroline Pantazis, Gary Aston-Jone. Prelimbic to Accumbens Core Pathway Is Recruited in a Dopamine-Dependent Manner to Drive Cued Reinstatement of Cocaine Seeking. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 33. 2017-07-14. PMID:27535915. |
glutamate inputs to nucleus accumbens (nac) facilitate conditioned drug-seeking behavior and primarily originate from medial prefrontal cortex (mpfc), basolateral amygdala (bla), and ventral subiculum of the hippocampus (vsub). |
2017-07-14 |
2023-08-13 |
rat |
| Lior Bikovsky, Ravit Hadar, María Luisa Soto-Montenegro, Julia Klein, Ina Weiner, Manuel Desco, Javier Pascau, Christine Winter, Clement Haman. Deep brain stimulation improves behavior and modulates neural circuits in a rodent model of schizophrenia. Experimental neurology. vol 283. issue Pt A. 2017-05-05. PMID:27302677. |
here, we use the poly i:c rat model of schizophrenia to study the effects of medial prefrontal cortex (mpfc) and nucleus accumbens (nacc) dbs on two behavioral schizophrenia-like deficits, i.e. |
2017-05-05 |
2023-08-13 |
rat |
| Jennifer M Bossert, Sweta Adhikary, Robyn St Laurent, Nathan J Marchant, Hui-Ling Wang, Marisela Morales, Yavin Shaha. Role of projections from ventral subiculum to nucleus accumbens shell in context-induced reinstatement of heroin seeking in rats. Psychopharmacology. vol 233. issue 10. 2017-02-10. PMID:26344108. |
we previously demonstrated that the projections from ventral medial prefrontal cortex (vmpfc) to nucleus accumbens (nac) shell play a role in this reinstatement. |
2017-02-10 |
2023-08-13 |
rat |
| Bangkun Yang, Chun Yang, Qian Ren, Ji-Chun Zhang, Qian-Xue Chen, Yukihiko Shirayama, Kenji Hashimot. Regional differences in the expression of brain-derived neurotrophic factor (BDNF) pro-peptide, proBDNF and preproBDNF in the brain confer stress resilience. European archives of psychiatry and clinical neuroscience. vol 266. issue 8. 2017-02-03. PMID:27094192. |
expression of preprobdnf, probdnf and bdnf pro-peptide in the medial prefrontal cortex of lh rats, but not non-lh rats, was significantly higher than control rats, although expression of these proteins in the nucleus accumbens of lh rats was significantly lower than control rats. |
2017-02-03 |
2023-08-13 |
rat |
| Chelsea A Vadnie, Jennifer Ayers-Ringler, Alfredo Oliveros, Osama A Abulseoud, Sun Choi, Mario J Hitschfeld, Doo-Sup Cho. Antipsychotic-like effects of a neurotensin receptor type 1 agonist. Behavioural brain research. vol 305. 2016-12-16. PMID:26909848. |
moreover, pd149163 inhibited gsk-3 activity in the nucleus accumbens and medial prefrontal cortex in the presence of amphetamine. |
2016-12-16 |
2023-08-13 |
mouse |
| Sujan C Das, Yusuf S Althobaiti, Fahad S Alshehri, Youssef Sar. Binge ethanol withdrawal: Effects on post-withdrawal ethanol intake, glutamate-glutamine cycle and monoamine tissue content in P rat model. Behavioural brain research. vol 303. 2016-12-13. PMID:26821293. |
in addition, the expression of glt-1, glast and xct were determined in both medial prefrontal cortex (mpfc) and nucleus accumbens (nac). |
2016-12-13 |
2023-08-13 |
rat |
| D-L Jiao, Y Liu, J-D Long, J Du, Y-Y Ju, G-Y Zan, J-G Liu, M Zha. Involvement of dorsal striatal α1-containing GABAA receptors in methamphetamine-associated rewarding memories. Neuroscience. vol 320. 2016-12-13. PMID:26868969. |
in this study, using the rat-conditioned place preference (cpp) model, a classic animal model for the reward-associated effects of addictive drugs, we found that the expression level of gabaa α1 subunits was significantly decreased in the dorsal striatum (dstr) after conditioned methamphetamine (meth) pairing, and no significant differences were observed in the other four rewarding memory-associated areas (medial prefrontal cortex (mpfc), nucleus accumbens (nac), amygdala (amy), and dorsal hippocampus (dh)). |
2016-12-13 |
2023-08-13 |
Not clear |
| K A Kerstetter, A M Wunsch, K G Nakata, E Donckels, J F Neumaier, Susan M Ferguso. Corticostriatal Afferents Modulate Responsiveness to Psychostimulant Drugs and Drug-Associated Stimuli. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 4. 2016-11-08. PMID:26289144. |
the medial prefrontal cortex (mpfc) and nucleus accumbens (nac) are both integral components of the corticobasal ganglia-thalamic circuitry that regulates addiction-related behaviors. |
2016-11-08 |
2023-08-13 |
Not clear |
| A F Carvalho, B A S Reyes, F Ramalhosa, N Sousa, E J Van Bockstael. Repeated administration of a synthetic cannabinoid receptor agonist differentially affects cortical and accumbal neuronal morphology in adolescent and adult rats. Brain structure & function. vol 221. issue 1. 2016-10-17. PMID:25348266. |
in the present study, we sought to investigate whether chronic systemic exposure to a synthetic cannabinoid receptor agonist causes morphological changes in the structure of dendrites and dendritic spines in adolescent and adult pyramidal neurons in the medial prefrontal cortex (mpfc) and medium spiny neurons (msn) in the nucleus accumbens (acb). |
2016-10-17 |
2023-08-13 |
human |
| Yukihiko Shirayama, Chun Yang, Ji-chun Zhang, Qian Ren, Wei Yao, Kenji Hashimot. Alterations in brain-derived neurotrophic factor (BDNF) and its precursor proBDNF in the brain regions of a learned helplessness rat model and the antidepressant effects of a TrkB agonist and antagonist. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 12. 2016-10-05. PMID:26419294. |
lh rats showed a reduction of bdnf in the medial prefrontal cortex (mpfc), ca3, and dentate gyrus (dg) of the hippocampus, whereas lh rats showed an increase in bdnf in the nucleus accumbens (nac). |
2016-10-05 |
2023-08-13 |
rat |
| Yi Zhang, Xiongzhao Zhu, Can Huang, Xiuwu Zhan. Molecular changes in the medial prefrontal cortex and nucleus accumbens are associated with blocking the behavioral sensitization to cocaine. Scientific reports. vol 5. 2016-09-23. PMID:26538265. |
molecular changes in the medial prefrontal cortex and nucleus accumbens are associated with blocking the behavioral sensitization to cocaine. |
2016-09-23 |
2023-08-13 |
rat |
| Yi Zhang, Xiongzhao Zhu, Can Huang, Xiuwu Zhan. Molecular changes in the medial prefrontal cortex and nucleus accumbens are associated with blocking the behavioral sensitization to cocaine. Scientific reports. vol 5. 2016-09-23. PMID:26538265. |
previous studies have demonstrated that cocaine-induced behavioral sensitization is associated with persistent functional and structural alterations in the medial prefrontal cortex (mpfc) and nucleus accumbens (nac); however, the molecular mechanisms underlying these changes have not been elucidated. |
2016-09-23 |
2023-08-13 |
rat |
| John R Mantsch, David A Baker, Douglas Funk, Anh D Lê, Yavin Shaha. Stress-Induced Reinstatement of Drug Seeking: 20 Years of Progress. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 1. 2016-09-22. PMID:25976297. |
neuropharmacology and circuitry studies indicate the involvement of crf and noradrenaline transmission in bed nucleus of stria terminalis and central amygdala, and dopamine, crf, kappa/dynorphin, and glutamate transmission in other components of the mesocorticolimbic dopamine system (ventral tegmental area, medial prefrontal cortex, orbitofrontal cortex, and nucleus accumbens). |
2016-09-22 |
2023-08-13 |
mouse |
| Achikam Haim, Christopher Albin-Brooks, Morgan Sherer, Emily Mills, Benedetta Leune. The effects of gestational stress and Selective Serotonin reuptake inhibitor antidepressant treatment on structural plasticity in the postpartum brain--A translational model for postpartum depression. Hormones and behavior. vol 77. 2016-09-15. PMID:25997412. |
moreover, the effect of gestational stress on postpartum mood is accompanied by structural modifications within the nucleus accumbens (nac) and the medial prefrontal cortex (mpfc)-limbic regions that have been linked to ppd. |
2016-09-15 |
2023-08-13 |
rat |
| M A De Luca, Z Bimpisidis, M Melis, M Marti, P Caboni, V Valentini, G Margiani, N Pintori, I Polis, G Marsicano, L H Parsons, G Di Chiar. Stimulation of in vivo dopamine transmission and intravenous self-administration in rats and mice by JWH-018, a Spice cannabinoid. Neuropharmacology. vol 99. 2016-08-30. PMID:26327678. |
in order to investigate the neurobiological substrates of jwh-018 actions, we studied by microdialysis in freely moving rats the effect of jwh-018 on extracellular dopamine (da) levels in the nucleus accumbens (nac) shell and core and in the medial prefrontal cortex (mpfc). |
2016-08-30 |
2023-08-13 |
mouse |
| Elizabeth N Holly, Christopher O Boyson, Sandra Montagud-Romero, Dirson J Stein, Kyle L Gobrogge, Joseph F DeBold, Klaus A Micze. Episodic Social Stress-Escalated Cocaine Self-Administration: Role of Phasic and Tonic Corticotropin Releasing Factor in the Anterior and Posterior Ventral Tegmental Area. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 14. 2016-08-15. PMID:27053215. |
reward and stress both activate ventral tegmental area (vta) dopamine neurons, increasing downstream extracellular dopamine concentration in the medial prefrontal cortex and nucleus accumbens. |
2016-08-15 |
2023-08-13 |
rat |
| Elaine B Sinclair, Kristen M Culbert, Dana R Gradl, Kimberlei A Richardson, Kelly L Klump, Cheryl L Sis. Differential mesocorticolimbic responses to palatable food in binge eating prone and binge eating resistant female rats. Physiology & behavior. vol 152. issue Pt A. 2016-08-08. PMID:26459117. |
the mesocorticolimbic reward circuit, including the nucleus accumbens and the medial prefrontal cortex, is likely involved because this circuit mediates the hedonic value and incentive salience of palatable foods (pf). |
2016-08-08 |
2023-08-13 |
rat |