All Relations between nucleus accumbens and medial prefrontal cortex

Publication Sentence Publish Date Extraction Date Species
Xiao Han, Man-Yi Jing, Tai-Yun Zhao, Ning Wu, Rui Song, Jin L. Role of dopamine projections from ventral tegmental area to nucleus accumbens and medial prefrontal cortex in reinforcement behaviors assessed using optogenetic manipulation. Metabolic brain disease. vol 32. issue 5. 2018-07-23. PMID:28523568. role of dopamine projections from ventral tegmental area to nucleus accumbens and medial prefrontal cortex in reinforcement behaviors assessed using optogenetic manipulation. 2018-07-23 2023-08-13 mouse
K M Braunscheidel, J T Gass, P J Mulholland, S B Floresco, J J Woodwar. Persistent cognitive and morphological alterations induced by repeated exposure of adolescent rats to the abused inhalant toluene. Neurobiology of learning and memory. vol 144. 2018-05-08. PMID:28720405. to determine whether cta alters the structural plasticity of brain areas involved in set-shifting and appetitive behaviors, we quantified basal dendritic spine morphology in dii-labeled pyramidal neurons in layer 5 of the medial prefrontal cortex (mpfc) and medium spiny neurons in the nucleus accumbens (nac). 2018-05-08 2023-08-13 human
Sabyasachi Dash, Muthukumar Balasubramaniam, Tanu Rana, Arthur Godino, Emily G Peck, Jeffery Shawn Goodwin, Fernando Villalta, Erin S Calipari, Eric J Nestler, Chandravanu Dash, Jui Pandhar. Poly (ADP-Ribose) Polymerase-1 (PARP-1) Induction by Cocaine Is Post-Transcriptionally Regulated by miR-125b. eNeuro. vol 4. issue 4. 2018-05-03. PMID:28828398. acute and chronic cocaine exposure resulted in the downregulation of mir-125b concurrent with upregulation of parp-1 in dopaminergic neuronal cells and nucleus accumbens (nac) of mice but not in the medial prefrontal cortex (pfc) or ventral tegmental area (vta). 2018-05-03 2023-08-13 mouse
Devesh Mishra, Jose Ignacio Pena-Bravo, Kah-Chung Leong, Antonieta Lavin, Carmela M Reiche. Methamphetamine self-administration modulates glutamate neurophysiology. Brain structure & function. vol 222. issue 5. 2018-04-17. PMID:27709300. we assessed pre- and postsynaptic changes in glutamate transmission in the medial prefrontal cortex (mpfc) and nucleus accumbens (nac) following daily 6-h meth self-administration. 2018-04-17 2023-08-13 Not clear
Shir Atzil, Alexandra Touroutoglou, Tali Rudy, Stephanie Salcedo, Ruth Feldman, Jacob M Hooker, Bradford C Dickerson, Ciprian Catana, Lisa Feldman Barret. Dopamine in the medial amygdala network mediates human bonding. Proceedings of the National Academy of Sciences of the United States of America. vol 114. issue 9. 2018-04-10. PMID:28193868. we applied a combined functional mri-pet scanner to simultaneously probe mothers' dopamine responses to their infants and the connectivity between the nucleus accumbens (nacc), the amygdala, and the medial prefrontal cortex (mpfc), which form an intrinsic network (referred to as the "medial amygdala network") that supports social functioning. 2018-04-10 2023-08-13 human
Hiram Tendilla-Beltrán, Luis Enrique Arroyo-García, Alfonso Diaz, Israel Camacho-Abrego, Fidel de la Cruz, Antonio Rodríguez-Moreno, Gonzalo Flore. The effects of amphetamine exposure on juvenile rats on the neuronal morphology of the limbic system at prepubertal, pubertal and postpubertal ages. Journal of chemical neuroanatomy. vol 77. 2018-01-31. PMID:27208629. the golgi-cox staining method was used to describe the neural morphology of five limbic regions: (layers 3 and 5) the medial prefrontal cortex (mpfc), the dorsal and ventral hippocampus, the nucleus accumbens and the amygdala, showing that amph induced changes at pubertal ages in arborization and spine density of these neurons, but interestingly these changes did not persist at postpubertal ages. 2018-01-31 2023-08-13 rat
Maria Vrettou, Linnea Granholm, Aniruddha Todkar, Kent W Nilsson, Åsa Wallén-Mackenzie, Ingrid Nylander, Erika Comasc. Ethanol affects limbic and striatal presynaptic glutamatergic and DNA methylation gene expression in outbred rats exposed to early-life stress. Addiction biology. vol 22. issue 2. 2018-01-30. PMID:26610727. brain regions of interest were the ventral tegmental area (vta), nucleus accumbens (acb), medial prefrontal cortex (mpfc) and dorsal striatum (dstr), all involved in mediating aspects of ethanol reward. 2018-01-30 2023-08-13 rat
Ravit Hadar, Le Dong, Lucia Del-Valle-Anton, Dilansu Guneykaya, Mareike Voget, Henriette Edemann-Callesen, Regina Schweibold, Anais Djodari-Irani, Thomas Goetz, Samuel Ewing, Helmut Kettenmann, Susanne A Wolf, Christine Winte. Deep brain stimulation during early adolescence prevents microglial alterations in a model of maternal immune activation. Brain, behavior, and immunity. vol 63. 2018-01-30. PMID:27939248. stimulation of either the medial prefrontal cortex or the nucleus accumbens normalized microglia density and soma size in main projection areas including the hippocampus and in the area around the electrode implantation. 2018-01-30 2023-08-13 rat
J J Walsh, M H Ha. The heterogeneity of ventral tegmental area neurons: Projection functions in a mood-related context. Neuroscience. vol 282. 2018-01-26. PMID:24931766. these neurons project to different brain regions, including the nucleus accumbens (nac), the medial prefrontal cortex (mpfc), and the amygdala. 2018-01-26 2023-08-13 Not clear
Iku Tsutsui-Kimura, Yu Ohmura, Takayuki Yoshida, Mitsuhiro Yoshiok. Milnacipran affects mouse impulsive, aggressive, and depressive-like behaviors in a distinct dose-dependent manner. Journal of pharmacological sciences. vol 134. issue 3. 2018-01-03. PMID:28694090. a milnacipran dose of 10 mg/kg suppressed all behaviors, which was accompanied by increased dopamine and serotonin levels in the medial prefrontal cortex (mpfc) but not in the nucleus accumbens (nac). 2018-01-03 2023-08-13 mouse
Egemen Kaya, Oguz Gozen, Muzeyyen Ugur, Ersin O Koylu, Lutfiye Kanit, Burcu Balka. Nicotine regulates cocaine-amphetamine-Regulated Transcript (Cart) in the mesocorticolimbic system. Synapse (New York, N.Y.). vol 70. issue 7. 2017-12-22. PMID:26990424. cart mrna and peptide levels in medial prefrontal cortex (mpfc), nucleus accumbens (nac), dorsal striatum (dst), amygdala (amg), lateral hypothalamic area (lha), and ventral tegmental area (vta) were measured by quantitative real-time pcr (qpcr) and western blot analysis, respectively. 2017-12-22 2023-08-13 rat
Courtney M Keller, Kelly N Breaux, Nicholas E Goeder. Effects of the combination of metyrapone and oxazepam on cocaine-induced increases in corticosterone in the medial prefrontal cortex and nucleus accumbens. Psychoneuroendocrinology. vol 77. 2017-12-07. PMID:28024272. the administration of cocaine resulted in an increase in corticosterone in the medial prefrontal cortex following vehicle pretreatment, which was not observed in the nucleus accumbens. 2017-12-07 2023-08-13 rat
Chengji Piao, Xiaofei Deng, Xingyue Wang, Yiran Yuan, Zhengkui Liu, Jing Lian. Altered function in medial prefrontal cortex and nucleus accumbens links to stress-induced behavioral inflexibility. Behavioural brain research. vol 317. 2017-12-05. PMID:27616342. the medial prefrontal cortex (mpfc) and its output area, the nucleus accumbens (nac), are implicated in mediating attentional set-shifting. 2017-12-05 2023-08-13 rat
Giannina Descalzi, Vasiliki Mitsi, Immanuel Purushothaman, Sevasti Gaspari, Kleopatra Avrampou, Yong-Hwee Eddie Loh, Li Shen, Venetia Zachario. Neuropathic pain promotes adaptive changes in gene expression in brain networks involved in stress and depression. Science signaling. vol 10. issue 471. 2017-11-28. PMID:28325815. using two mouse models of neuropathic pain and depression [spared nerve injury (sni) and chronic unpredictable stress (cus)], we performed next-generation rna sequencing and pathway analysis to monitor changes in gene expression in the nucleus accumbens (nac), the medial prefrontal cortex (mpfc), and the periaqueductal gray (pag). 2017-11-28 2023-08-13 mouse
Eduardo A V Marinho, Alexandre J Oliveira-Lima, Thais S Yokoyama, Renan Santos-Baldaia, Luciana T C Ribeiro, Marilia A Baldaia, Raphael Wuo da Silva, Andre Willian Hollais, Fernanda Talhati, Beatriz Monteiro Longo, Lais Fernanda Berro, Roberto Frussa-Filh. Post-sensitization treatment with rimonabant blocks the expression of cocaine-induced behavioral sensitization and c-Fos protein in mice. Pharmacology, biochemistry, and behavior. vol 156. 2017-11-09. PMID:28366798. c-fos protein expression was evaluated in the nucleus accumbens (nacc), ventral tegmental area (vta), basolateral amygdala (bla), medial prefrontal cortex (mpfc) and caudate-putamen (cpu) after the last (cocaine) challenge. 2017-11-09 2023-08-13 mouse
Paige M Dingess, Rebecca A Darling, E Kurt Dolence, Bruce W Culver, Travis E Brow. Exposure to a diet high in fat attenuates dendritic spine density in the medial prefrontal cortex. Brain structure & function. vol 222. issue 2. 2017-10-20. PMID:26983815. to test whether dietary fat may induce structural plasticity we placed rats on one of three dietary conditions: ad libitum standard chow (sc), ad libitum 60 % hf (hf-al), or calorically matched 60 % hf (hf-cm) for 3 weeks and then quantified dendritic spine density and type on basal and apical dendrites of pyramidal cells in layer v of the medial prefrontal cortex (mpfc) and medium spiny neurons (msns) of the nucleus accumbens. 2017-10-20 2023-08-13 rat
Karl T Schmidt, Jason P Schroeder, Stephanie L Foster, Katherine Squires, Brilee M Smith, Elizabeth G Pitts, Michael P Epstein, David Weinshenke. Norepinephrine regulates cocaine-primed reinstatement via α1-adrenergic receptors in the medial prefrontal cortex. Neuropharmacology. vol 119. 2017-08-31. PMID:28392265. furthermore, administration of the α1ar antagonist terazosin in the medial prefrontal cortex (mpfc), but not the ventral tegmental area (vta) or nucleus accumbens (nac) shell, attenuated cocaine-primed reinstatement. 2017-08-31 2023-08-13 rat
Patricia Muñoz-Villegas, Verónica Mireya Rodríguez, Magda Giordano, Jorge Juáre. Risk-taking, locomotor activity and dopamine levels in the nucleus accumbens and medial prefrontal cortex in male rats treated prenatally with alcohol. Pharmacology, biochemistry, and behavior. vol 153. 2017-08-25. PMID:28011337. risk-taking, locomotor activity and dopamine levels in the nucleus accumbens and medial prefrontal cortex in male rats treated prenatally with alcohol. 2017-08-25 2023-08-13 rat
Patricia Muñoz-Villegas, Verónica Mireya Rodríguez, Magda Giordano, Jorge Juáre. Risk-taking, locomotor activity and dopamine levels in the nucleus accumbens and medial prefrontal cortex in male rats treated prenatally with alcohol. Pharmacology, biochemistry, and behavior. vol 153. 2017-08-25. PMID:28011337. in addition, da levels in the nucleus accumbens (nacc) and medial prefrontal cortex (mpfc) in response to methylphenidate (mp) were assessed. 2017-08-25 2023-08-13 rat
Julie A D Dela Cruz, Tricia Coke, Richard J Bodna. Simultaneous Detection of c-Fos Activation from Mesolimbic and Mesocortical Dopamine Reward Sites Following Naive Sugar and Fat Ingestion in Rats. Journal of visualized experiments : JoVE. issue 114. 2017-08-14. PMID:27583636. thus, sugar intake elicits da release and increases c-fos-like immunoreactivity (fli) from individual vta da projection zones including the nucleus accumbens (nac), amygdala (amy) and medial prefrontal cortex (mpfc) as well as the dorsal striatum. 2017-08-14 2023-08-13 rat