| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Katsuyuki Kaneda, Satoshi Deyama, Eiichi Hinoi, Junko Yanagida, Tong Zhang, Hitoki Sasas. [Analyses of cocaine rewarding memories by AAV vector-induced introduction of DREADD system]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 153. issue 5. 2019-08-13. PMID:31092754. |
the development and persistence of drug addiction are associated with the activation and adaptation of the brain reward circuitry, which consists of dopaminergic projection from the ventral tegmental area to the nucleus accumbens (nac) and the medial prefrontal cortex (mpfc). |
2019-08-13 |
2023-08-13 |
mouse |
| Sanjeev K Bhardwaj, Fatéma Dodat, Daniel Lévesque, Lalit K Srivastav. Altered regulation of Nur77 nuclear receptor gene expression in the mesocorticolimbic regions of rat brain by amphetamine sensitization. Brain research. vol 1694. 2019-07-11. PMID:29750935. |
here we evaluated changes in nur77 mrna levels in the medial prefrontal cortex (mpfc), dorsal striatum (str) and nucleus accumbens (nac) of rats receiving a repeated, sensitizing regimen of amphetamine (amph). |
2019-07-11 |
2023-08-13 |
rat |
| Sarah M Tashjian, Adriana Galvá. The Role of Mesolimbic Circuitry in Buffering Election-Related Distress. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 38. issue 11. 2019-07-05. PMID:29431648. |
we used functional magnetic resonance imaging and psychological measures to test the hypotheses that neural response to reward, probing the nucleus accumbens (nacc) and medial prefrontal cortex (mpfc), and social support would ameliorate the effects of election distress among those who felt negatively affected by the result. |
2019-07-05 |
2023-08-13 |
human |
| Alaa M Hammad, Fawaz Alasmari, Youssef Sari, F Scott Hall, Amit K Tiwar. Alcohol and Cocaine Exposure Modulates ABCB1 and ABCG2 Transporters in Male Alcohol-Preferring Rats. Molecular neurobiology. vol 56. issue 3. 2019-07-01. PMID:29978425. |
in this study, we determined the effects of voluntary ethanol consumption following repeated exposure to cocaine or vehicle on the relative mrna and protein expression of abcg2/abcg2 and abcb1/abcb1 in the nucleus accumbens (nac) and medial prefrontal cortex (mpfc) of male alcohol-preferring (p) rats. |
2019-07-01 |
2023-08-13 |
rat |
| Daniel Knowland, Byung Kook Li. Circuit-based frameworks of depressive behaviors: The role of reward circuitry and beyond. Pharmacology, biochemistry, and behavior. vol 174. 2019-06-24. PMID:29309799. |
in particular, areas such as the ventral tegmental area (vta), nucleus accumbens (nac), and ventral pallidum (vp) are thought to generally promote reward, with the medial prefrontal cortex (mpfc) providing top-down control of reward seeking. |
2019-06-24 |
2023-08-13 |
Not clear |
| b' Przemys\\xc5\\x82aw Kowia\\xc5\\x84ski, Gra\\xc5\\xbcyna Lietzau, Aleksandra Steliga, Ewelina Czuba, Beata Ludkiewicz, Monika Wa\\xc5\\x9bkow, Jan H Spodnik, Janusz Mory\\xc5\\x9. Nicotine-induced CREB and DeltaFosB activity is modified by caffeine in the brain reward system of the rat. Journal of chemical neuroanatomy. vol 88. 2019-05-14. PMID:29100904.' |
we aimed at determining the effect of caffeine and nicotine, applied separately or simultaneously, on activation of six structures of the brain reward system: nucleus accumbens (nac), ventral tegmental area (vta), amygdala (amg), hippocampus (hip), medial prefrontal cortex (mpfr) and dorsal striatum (cdp) in the adult male wistar rats. |
2019-05-14 |
2023-08-13 |
rat |
| Matthew Hearin. Prefrontal-accumbens opioid plasticity: Implications for relapse and dependence. Pharmacological research. vol 139. 2019-05-13. PMID:30465850. |
we discuss what is known regarding opioid-induced adaptations in intrinsic membrane physiology and pre-/postsynaptic neurotransmission in principle pyramidal and medium spiny neurons in the medial prefrontal cortex and nucleus accumbens from electrophysiological studies and explore how circuit specific adaptations may contribute to unique facets of opioid addiction. |
2019-05-13 |
2023-08-13 |
Not clear |
| Fabrizio Sanna, Laura Poddighe, Maria Pina Serra, Marianna Boi, Jessica Bratzu, Francesco Sanna, Maria Giuseppa Corda, Osvaldo Giorgi, Maria Rosaria Melis, Antonio Argiolas, Marina Quart. c-Fos, ΔFosB, BDNF, trkB and Arc Expression in the Limbic System of Male Roman High- and Low-Avoidance Rats that Show Differences in Sexual Behavior: Effect of Sexual Activity. Neuroscience. vol 396. 2019-04-01. PMID:30423358. |
since sexual activity is a natural reward that induces neural activation and synaptic plastic changes in limbic brain areas, we studied whether the differences in sexual activity between these rat lines are accompanied by changes in the expression of markers of neural activation and plasticity, i.e., c-fos, Δfosb (a truncated form of fosb), brain-derived neurotrophic factor (bdnf) and its tyrosine kinase receptor b (trkb) and activity regulated cytoskeleton-associated (arc) protein in the ventral tegmental area (vta), nucleus accumbens (acb) (core and shell) and medial prefrontal cortex (mpfc) of sexually naïve and experienced rha and rla rats by western blot and/or immunohistochemistry. |
2019-04-01 |
2023-08-13 |
rat |
| Di Liu, Qian-Qian Tang, Cui Yin, Yu Song, Yan Liu, Jun-Xia Yang, He Liu, Yue-Man Zhang, Si-Yin Wu, Ying Song, Barbara Juarez, Hai-Lei Ding, Ming-Hu Han, Hongxing Zhang, Jun-Li Ca. Brain-derived neurotrophic factor-mediated projection-specific regulation of depressive-like and nociceptive behaviors in the mesolimbic reward circuitry. Pain. vol 159. issue 1. 2019-03-21. PMID:29076919. |
we demonstrated that cms decreased the firing activity in vta projecting to medial prefrontal cortex (vta → mpfc), but not in vta to nucleus accumbens (vta → nac), da neurons. |
2019-03-21 |
2023-08-13 |
mouse |
| Aman Asif-Malik, Daniel Dautan, Andrew M J Young, Todor V Gerdjiko. Altered cortico-striatal crosstalk underlies object recognition memory deficits in the sub-chronic phencyclidine model of schizophrenia. Brain structure & function. vol 222. issue 7. 2019-02-21. PMID:28293729. |
given that network activity across regions encompassing medial prefrontal cortex (mpfc) and nucleus accumbens (nac) plays a significant role in motivational and cognitive tasks, we measured activity across cortico-striatal pathways in pcp-treated rats to characterize neural enabling and encoding of task performance in a novel object recognition task. |
2019-02-21 |
2023-08-13 |
rat |
| Katherine T Martucci, Nicholas Borg, Kelly H MacNiven, Brian Knutson, Sean C Macke. Altered prefrontal correlates of monetary anticipation and outcome in chronic pain. Pain. vol 159. issue 8. 2019-02-21. PMID:29790868. |
group fmri analyses were conducted to determine predetermined region of interest, nucleus accumbens (nacc) and medial prefrontal cortex (mpfc), responses to potential gains, potential losses, reward outcomes, and punishment outcomes. |
2019-02-21 |
2023-08-13 |
human |
| Ying Zeng, Di Hu, Wei Yang, Emi Hayashinaka, Yasuhiro Wada, Yasuyoshi Watanabe, Qunli Zeng, Yilong Cu. A voxel-based analysis of neurobiological mechanisms in placebo analgesia in rats. NeuroImage. vol 178. 2019-02-19. PMID:29883731. |
we show here that gabapentin-based pavlovian conditioning successfully induced placebo analgesia in neuropathic pain model rats and hierarchical brain regions are involved in placebo analgesia in rats, including the prelimbic cortex (prl) of the medial prefrontal cortex (mpfc), nucleus accumbens (nac), ventrolateral periaqueductal gray matter (vlpag), etc. |
2019-02-19 |
2023-08-13 |
rat |
| Daniel F Hill, Kate L Parent, Christopher W Atcherley, Stephen L Cowen, Michael L Heie. Differential release of dopamine in the nucleus accumbens evoked by low-versus high-frequency medial prefrontal cortex stimulation. Brain stimulation. vol 11. issue 2. 2019-01-28. PMID:29239776. |
differential release of dopamine in the nucleus accumbens evoked by low-versus high-frequency medial prefrontal cortex stimulation. |
2019-01-28 |
2023-08-13 |
Not clear |
| Daniel F Hill, Kate L Parent, Christopher W Atcherley, Stephen L Cowen, Michael L Heie. Differential release of dopamine in the nucleus accumbens evoked by low-versus high-frequency medial prefrontal cortex stimulation. Brain stimulation. vol 11. issue 2. 2019-01-28. PMID:29239776. |
the medial prefrontal cortex (mpfc) coordinates goal-directed behaviors, which may be mediated through mpfc regulation of dopamine release in the nucleus accumbens (nac). |
2019-01-28 |
2023-08-13 |
Not clear |
| Katherine N Wright, Amanda M Dossat, Caroline E Strong, Lindsay L Sailer, Samantha M Pavlock, Mohamed Kabba. Optogenetic inhibition of medial prefrontal cortex projections to the nucleus accumbens core and methyl supplementation via L-Methionine attenuates cocaine-primed reinstatement. Integrative zoology. vol 13. issue 6. 2019-01-18. PMID:30318755. |
indeed, the medial prefrontal cortex (mpfc) projections to the nucleus accumbens (nac) are critically important for reinstated cocaine-seeking in a rodent model of cocaine relapse. |
2019-01-18 |
2023-08-13 |
rat |
| H Schoch, M Y Huerta, C M Ruiz, M R Farrell, K M Jung, J J Huang, R R Campbell, D Piomelli, S V Mahle. Adolescent cannabinoid exposure effects on natural reward seeking and learning in rats. Psychopharmacology. vol 235. issue 1. 2018-12-11. PMID:29022083. |
as a result, adolescent cannabinoid receptor stimulation (acrs) with phytocannabinoids or synthetic agonists like "spice" cause robust and persistent changes in both behavior and circuit architecture in rodents, including in reward-related regions like medial prefrontal cortex and nucleus accumbens (nac). |
2018-12-11 |
2023-08-13 |
rat |
| Raúl López-Arnau, Mario Buenrostro-Jáuregui, Jorge Camarasa, David Pubill, Elena Escubed. Effect of the combination of mephedrone plus ethanol on serotonin and dopamine release in the nucleus accumbens and medial prefrontal cortex of awake rats. Naunyn-Schmiedeberg's archives of pharmacology. vol 391. issue 3. 2018-11-26. PMID:29349706. |
effect of the combination of mephedrone plus ethanol on serotonin and dopamine release in the nucleus accumbens and medial prefrontal cortex of awake rats. |
2018-11-26 |
2023-08-13 |
rat |
| Raúl López-Arnau, Mario Buenrostro-Jáuregui, Jorge Camarasa, David Pubill, Elena Escubed. Effect of the combination of mephedrone plus ethanol on serotonin and dopamine release in the nucleus accumbens and medial prefrontal cortex of awake rats. Naunyn-Schmiedeberg's archives of pharmacology. vol 391. issue 3. 2018-11-26. PMID:29349706. |
in the present study, we investigated the combined effects of meph plus ethanol (etoh) on neurotransmitter release in the nucleus accumbens (nac) and the medial prefrontal cortex (mpfc). |
2018-11-26 |
2023-08-13 |
rat |
| Bryan Kolb, Yilin Li, Terry Robinson, Linda A Parke. THC alters alters morphology of neurons in medial prefrontal cortex, orbital prefrontal cortex, and nucleus accumbens and alters the ability of later experience to promote structural plasticity. Synapse (New York, N.Y.). vol 72. issue 3. 2018-10-29. PMID:29178372. |
repeated exposure to delta 9-tetrahydrocannabinol (thc) changes the morphology of dendrites in medial prefrontal cortex (mpfc) and nucleus accumbens (nacc). |
2018-10-29 |
2023-08-13 |
rat |
| Romana Koprdova, Jana Osacka, Mojmir Mach, Alexander Kis. Acute Impact of Selected Pyridoindole Derivatives on Fos Expression in Different Structures of the Rat Brain. Cellular and molecular neurobiology. vol 38. issue 1. 2018-08-13. PMID:28695319. |
the impacts of three pyridoindole derivatives (pds), designated as pd144, pd143, and pd104, which have previously been shown to have antidepressant (pd144) and anxiolytic (pd143, pd104) properties, were investigated on the fos expressions in 11 different rat brain areas, including the medial prefrontal cortex, striatum, septum, accumbens nucleus (shell, core), bed nucleus of the stria terminalis, hypothalamic paraventricular nucleus, central amygdala, locus coeruleus, dorsal raphe nucleus, and the solitary tract nucleus. |
2018-08-13 |
2023-08-13 |
rat |