| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Denise F Happ, Gregers Wegener, R Andrew Taske. Effect of ischemic lesions in medial prefrontal cortex and nucleus accumbens on affective behavior in rats. Behavioural brain research. vol 378. 2021-04-28. PMID:31521735. |
effect of ischemic lesions in medial prefrontal cortex and nucleus accumbens on affective behavior in rats. |
2021-04-28 |
2023-08-13 |
mouse |
| Joseph Clerke, Patricia Preston-Ferrer, Ioannis S Zouridis, Audrey Tissot, Laura Batti, Fabian F Voigt, Stephane Pagès, Andrea Burgalossi, Manuel Mamel. Output-Specific Adaptation of Habenula-Midbrain Excitatory Synapses During Cocaine Withdrawal. Frontiers in synaptic neuroscience. vol 13. 2021-04-21. PMID:33867967. |
vta neurons receiving lhb inputs project their axons to medial prefrontal cortex (mpfc), nucleus accumbens (nac), and lateral hypothalamus (lh). |
2021-04-21 |
2023-08-13 |
mouse |
| Xiaolu Yu, Mannan Abdul, Bing-Qian Fan, Lilu Zhang, Xing Lin, Yan Wu, Hui Fu, Qisi Lin, Hao Men. The release of exosomes in the medial prefrontal cortex and nucleus accumbens brain regions of chronic constriction injury (CCI) model mice could elevate the pain sensation. Neuroscience letters. vol 723. 2021-04-19. PMID:31981720. |
the medial prefrontal cortex (mpfc) and nucleus accumbens (nac) brain regions are known to involve in pain modulation. |
2021-04-19 |
2023-08-13 |
mouse |
| Lailun Nahar, Caleb A Grant, Cameron Hewett, Diego Cortes, Ashlie N Reker, Seungwoo Kang, Doo-Sup Choi, Hyung W Na. Regulation of Pv-specific interneurons in the medial prefrontal cortex and reward-seeking behaviors. Journal of neurochemistry. vol 156. issue 2. 2021-04-08. PMID:32594517. |
interestingly, our microdialysis results demonstrate that alcohol exposure inhibits pv-fsi functioning in the medial prefrontal cortex (mpfc) and this consequently can regulate glutamate levels downstream in the nucleus accumbens. |
2021-04-08 |
2023-08-13 |
mouse |
| X Li, L-S Xu, Y-F Xu, Q Yang, Z-X Fang, M Yao, W-Y Che. The gene regulatory network in different brain regions of neuropathic pain mouse models. European review for medical and pharmacological sciences. vol 24. issue 9. 2021-03-31. PMID:32432769. |
neuropathic pain is often associated with structural and functional abnormalities in multiple brain regions, and its regulation has been shown to correspond with the forebrain, including nucleus accumbens (nac), medial prefrontal cortex (mpfc) and periaqueductal gray (pag). |
2021-03-31 |
2023-08-13 |
mouse |
| Jing Wang, Simin Lai, Guodong Li, Ting Zhou, Biao Wang, Fang Cao, Teng Chen, Xia Zhang, Yanjiong Che. Microglial activation contributes to depressive-like behavior in dopamine D3 receptor knockout mice. Brain, behavior, and immunity. vol 83. 2021-03-08. PMID:31626970. |
we previously demonstrated that the dopamine d3 receptor (d3r) inhibitor, ngb2904, increases susceptibility to depressive-like symptoms, elevates pro-inflammatory cytokine expression, and alters brain-derived neurotrophic factor (bdnf) levels in mesolimbic dopaminergic regions, including the medial prefrontal cortex (mpfc), nucleus accumbens (nac), and ventral tegmental area (vta) in mice. |
2021-03-08 |
2023-08-13 |
mouse |
| Omer Horovitz, Ziv Ardi, Shiri Karni Ashkenazi, Gilad Ritov, Rachel Anunu, Gal Richter-Levi. Network Neuromodulation of Opioid and GABAergic Receptors Following a Combination of "Juvenile" and "Adult Stress" in Rats. International journal of molecular sciences. vol 21. issue 15. 2021-02-22. PMID:32751453. |
two weeks following behavioral assessment in adulthood, gabaar α1 and α2 subunits and κ opioid receptor expression levels were measured in the medial prefrontal cortex (mpfc), nucleus accumbens (nac), amygdala, and periaqueductal gray (pag). |
2021-02-22 |
2023-08-13 |
rat |
| Grace McIlvain, Rebecca G Clements, Emily M Magoon, Jeffrey M Spielberg, Eva H Telzer, Curtis L Johnso. Viscoelasticity of reward and control systems in adolescent risk taking. NeuroImage. vol 215. 2021-02-19. PMID:32298793. |
the socioemotional system (e.g., nucleus accumbens), which is instrumental in reward response, shows a relatively earlier development trajectory than the cognitive control system (e.g., medial prefrontal cortex), which regulates impulse response. |
2021-02-19 |
2023-08-13 |
Not clear |
| Wei Yuan, Laifu Li, Wenjuan Hou, Zhixiong He, Limin Wang, Jing Zhang, Yang Yang, Wenqi Cai, Qianqian Guo, Xueni Zhang, Rui Jia, Zhenmin Lian, Fadao Ta. Preweaning Paternal Deprivation Impacts Parental Responses to Pups and Alters the Serum Oxytocin and Corticosterone Levels and Oxytocin Receptor, Vasopressin 1A Receptor, Oestrogen Receptor, Dopamine Type I Receptor, Dopamine Type II Receptor Levels in Relevant Brain Regions in Adult Mandarin Voles. Neuroendocrinology. vol 110. issue 3-4. 2021-02-15. PMID:31256151. |
furthermore, in both males and females, ppd decreased the expression of oxytocin receptor mrna and protein in the medial preoptic area (mpoa), nucleus accumbens (nacc) and medial prefrontal cortex (mpfc), but increased it in the medial amygdala (mea) and decreased the expression of oestrogen receptor mrna and protein in the mpoa. |
2021-02-15 |
2023-08-13 |
Not clear |
| Mei Huang, Wenqi He, Lakshmi Rajagopal, Andrea Kudwa, Dimitri E Grigoriadis, Herbert Y Meltze. Effects of NBI-98782, a selective vesicular monoamine transporter 2 (VMAT2) inhibitor, on neurotransmitter efflux and phencyclidine-induced locomotor activity: Relevance to tardive dyskinesia and antipsychotic action. Pharmacology, biochemistry, and behavior. vol 190. 2021-01-07. PMID:32084491. |
we utilized microdialysis in awake, freely moving mice to determine the effect of nbi-98782, the active metabolite of valbenazine, alone, or in combination with several antipsychotic drugs (apds), to influence neurotransmitter efflux in the medial prefrontal cortex (mpfc), dorsal striatum (dstr), hippocampus and nucleus accumbens (nac); we also compared it with tetrabenazine, the prototypical vmat2 inhibitor. |
2021-01-07 |
2023-08-13 |
mouse |
| Patricia Barra de la Tremblaye, Nicolas Narvaez Linares, Sarah Schock, Hélène Plamondo. Activation of CRHR1 receptors regulates social and depressive-like behaviors and expression of BDNF and TrkB in mesocorticolimbic regions following global cerebral ischemia. Experimental neurology. vol 284. issue Pt A. 2021-01-05. PMID:27498336. |
immunohistochemistry, western blot and rt-pcr were used to assess bdnf and trkb receptor levels in subregions of the medial prefrontal cortex (mpfc), nucleus accumbens (nac) and ventral tegmental area (vta) 30days post-ischemia. |
2021-01-05 |
2023-08-13 |
rat |
| Katelyn L Low, Ryan J Tomm, Chunqi Ma, Daniel J Tobiansky, Stan B Floresco, Kiran K Som. Effects of aging on testosterone and androgen receptors in the mesocorticolimbic system of male rats. Hormones and behavior. vol 120. 2020-12-21. PMID:31954104. |
here, we examined young adult (5 months) and aged (22 months) male fischer 344 × brown norway rats, and measured systemic t levels in serum and local t levels in microdissected nodes of the mesocorticolimbic system (ventral tegmental area (vta), nucleus accumbens (nac), medial prefrontal cortex (mpfc), and orbitofrontal cortex (ofc)). |
2020-12-21 |
2023-08-13 |
rat |
| Jeff Boissoneault, Bethany Stennett, Michael E Robinso. Acute alcohol intake alters resting state functional connectivity of nucleus accumbens with pain-related corticolimbic structures. Drug and alcohol dependence. vol 207. 2020-11-23. PMID:31891860. |
the nucleus accumbens (nac) is a ventral striatal structure underlying reward, reinforcement, and motivation, with extensive anatomic and functional connections to a wide range of affective processing structures (medial prefrontal cortex (mpfc), amygdala, and insula). |
2020-11-23 |
2023-08-13 |
Not clear |
| Wenbo Zhao, Ying Hu, Chuangang Li, Ning Li, Shaowei Zhu, Xu Tan, Meng Li, Yue Zhang, Zheng Xu, Zhaoxi Ding, Lingming Hu, Zengxun Liu, Jinhao Su. Transplantation of fecal microbiota from patients with alcoholism induces anxiety/depression behaviors and decreases brain mGluR1/PKC ε levels in mouse. BioFactors (Oxford, England). vol 46. issue 1. 2020-11-19. PMID:31518024. |
then we evaluated their alcohol preference degree, anxiety, and depression-like behaviors and social interaction behaviors, together with molecular changes in the medial prefrontal cortex (mpfc) and nucleus accumbens (nac). |
2020-11-19 |
2023-08-13 |
mouse |
| Richard Quansah Amissah, Sandrine Chometton, Juliane Calvez, Genevieve Guèvremont, Elena Timofeeva, Igor Timofee. Differential Expression of DeltaFosB in Reward Processing Regions Between Binge Eating Prone and Resistant Female Rats. Frontiers in systems neuroscience. vol 14. 2020-11-13. PMID:33177996. |
the number of Δfosb-expressing neurons was: (1) higher in bep than ber rats in reward processing areas [medial prefrontal cortex (mpfc), nucleus accumbens (acb), and ventral tegmental area (vta)]; (2) similar in taste processing areas [insular cortex, ic and parabrachial nucleus (pbn)]; and (3) higher in the paraventricular nucleus of bep than ber rats, but not different in the locus coeruleus (lc), which are stress processing structures. |
2020-11-13 |
2023-08-13 |
rat |
| Qingxiao Hong, Jing Liu, Zi Lin, Dingding Zhuang, Wenjin Xu, Zemin Xu, Miaojun Lai, Huaqiang Zhu, Wenhua Zhou, Huifen Li. Histone 3 lysine 9 acetylation of BRG1 in the medial prefrontal cortex is associated with heroin self‑administration in rats. Molecular medicine reports. vol 21. issue 1. 2020-11-06. PMID:31939625. |
chromatin immunoprecipitation followed by reverse transcription‑quantitative pcr (rt‑qpcr) was used to detect the accumulation of h3k9ac on brg1 in the medial prefrontal cortex (mpfc) and nucleus accumbens (nac) following heroin self‑administration. |
2020-11-06 |
2023-08-13 |
rat |
| Courtney M Keller, Nicholas E Goeder. Lack of effect of the combination of metyrapone and oxazepam on brain dopamine. Brain research. vol 1724. 2020-10-29. PMID:31491421. |
in vivo microdialysis studies in the medial prefrontal cortex and nucleus accumbens revealed that met-ox produced no measurable effects on cocaine-induced increases in dopamine. |
2020-10-29 |
2023-08-13 |
human |
| Sarah B Winokur, Keianna L Lopes, Yashaswani Moparthi, Mariana Pereir. Depression-related disturbances in rat maternal behaviour are associated with altered monoamine levels within mesocorticolimbic structures. Journal of neuroendocrinology. vol 31. issue 9. 2020-10-13. PMID:31265182. |
levels of the monoamine neurotransmitters, dopamine, noradrenaline and serotonin, as well as their major metabolites, were measured within the medial prefrontal cortex, striatum, nucleus accumbens and medial preoptic area of sd and wky mothers at early (postpartum day [ppd]7-8), late (ppd15-16) and weaning (ppd25) postpartum stages using high-performance liquid chromatography with electrochemical detection. |
2020-10-13 |
2023-08-13 |
rat |
| Gerdien A H Korte-Bouws, Floor van Heesch, Koen G C Westphal, Lisa M J Ankersmit, Edwin M van Oosten, Onur Güntürkün, S Mechiel Kort. Bacterial Lipopolysaccharide Increases Serotonin Metabolism in Both Medial Prefrontal Cortex and Nucleus Accumbens in Male Wild Type Rats, but Not in Serotonin Transporter Knockout Rats. Pharmaceuticals (Basel, Switzerland). vol 11. issue 3. 2020-10-01. PMID:29976854. |
bacterial lipopolysaccharide increases serotonin metabolism in both medial prefrontal cortex and nucleus accumbens in male wild type rats, but not in serotonin transporter knockout rats. |
2020-10-01 |
2023-08-13 |
rat |
| Gerdien A H Korte-Bouws, Floor van Heesch, Koen G C Westphal, Lisa M J Ankersmit, Edwin M van Oosten, Onur Güntürkün, S Mechiel Kort. Bacterial Lipopolysaccharide Increases Serotonin Metabolism in Both Medial Prefrontal Cortex and Nucleus Accumbens in Male Wild Type Rats, but Not in Serotonin Transporter Knockout Rats. Pharmaceuticals (Basel, Switzerland). vol 11. issue 3. 2020-10-01. PMID:29976854. |
administered lps increased extracellular monoamine metabolite levels in the nucleus accumbens (nac) and medial prefrontal cortex (mpfc), which was completely, or at least partly, prevented by pretreatment with a triple reuptake inhibitor that also blocks the serotonin (5-ht) transporter (sert). |
2020-10-01 |
2023-08-13 |
rat |