| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ali Birdogan, Elif Salur, Fulya Tuzcu, Ramazan C Gokmen, Meliha Ozturk Bintepe, Buket Aypar, Aysegul Keser, Burcu Balkan, Ersin O Koylu, Lutfiye Kanit, Oguz Goze. Chronic oral nicotine administration and withdrawal regulate the expression of neuropeptide Y and its receptors in the mesocorticolimbic system. Neuropeptides. vol 90. 2021-11-22. PMID:34425507. |
on the other hand, 24- and 48-h withdrawals increased npy mrna levels in the amygdala and medial prefrontal cortex (mpfc), y1 and y2 mrna levels in the nucleus accumbens and mpfc, and y5 mrna levels in the mpfc. |
2021-11-22 |
2023-08-13 |
rat |
| Bai-Chuang Shyu, Zhi-Yue Gao, José Jiun-Shian Wu, Alan Bo Han He, Cai-N Cheng, Andrew Chih Wei Huan. Methamphetamine and Modulation Functionality of the Prelimbic Cortex for Developing a Possible Treatment of Alzheimer's Disease in an Animal Model. Frontiers in aging neuroscience. vol 13. 2021-11-10. PMID:34744692. |
this study examined whether a low dose of mamph can induce conditioned taste aversion (cta) learning, or can increase plasma corticosterone levels, neural activity, and neural plasticity in the medial prefrontal cortex (mpfc) (responsible for cognitive function), the nucleus accumbens (nac) and the amygdala (related to rewarding and aversive emotion), and the hippocampus (responsible for spatial learning). |
2021-11-10 |
2023-08-13 |
rat |
| Maria Vrettou, Liying Yan, Kent W Nilsson, Åsa Wallén-Mackenzie, Ingrid Nylander, Erika Comasc. DNA methylation of Vesicular Glutamate Transporters in the mesocorticolimbic brain following early-life stress and adult ethanol exposure-an explorative study. Scientific reports. vol 11. issue 1. 2021-11-08. PMID:34321562. |
the present study aimed to investigate whether dna methylation of the vesicular glutamate transporters (vglut)1-3 is related to previously observed vglut1-3 transcriptional differences in the ventral tegmental area (vta), nucleus accumbens (acb), dorsal striatum (dstr) and medial prefrontal cortex (mpfc) of adult rats exposed to els, modelled by maternal separation, and voluntary ethanol consumption. |
2021-11-08 |
2023-08-13 |
rat |
| Jessica Hayes, Bettina Laursen, Elin Eneberg, Jan Kehler, Lars Kyhn Rasmussen, Morten Langgard, Jesper F Bastlund, Todor V Gerdjiko. Phosphodiesterase type 1 inhibition alters medial prefrontal cortical activity during goal-driven behaviour and partially reverses neurophysiological deficits in the rat phencyclidine model of schizophrenia. Neuropharmacology. vol 186. 2021-11-05. PMID:33444639. |
to address this, we recorded single unit activity in medial prefrontal cortex (mpfc) and nucleus accumbens (nac) in lister hooded rats treated with the pde1b inhibitor lu af64386 and tested in the 5-choice serial reaction time task (5-csrtt). |
2021-11-05 |
2023-08-13 |
rat |
| Hashem Saberian, Afsaneh Asgari Taei, Anahita Torkaman-Boutorabi, Esmail Riahi, Samaneh Aminyavari, Ayeh Naghizadeh, Maryam Farahmandfa. Effect of histone acetylation on maintenance and reinstatement of morphine-induced conditioned place preference and ΔFosB expression in the nucleus accumbens and prefrontal cortex of male rats. Behavioural brain research. vol 414. 2021-11-04. PMID:34302880. |
h4 acetylation and Δfosb expression in the nucleus accumbens (nac) and medial prefrontal cortex (mpfc) were assessed on the last day of extinction and the following cpp reinstatement. |
2021-11-04 |
2023-08-13 |
rat |
| Young-Jung Kim, Shi-Xun Ma, Kwang-Hyun Hur, Youyoung Lee, Yong-Hyun Ko, Bo-Ram Lee, Seon-Kyung Kim, Su-Jeong Sung, Kyeong-Man Kim, Hyoung-Chun Kim, Seok-Yong Lee, Choon-Gon Jan. New designer phenethylamines 2C-C and 2C-P have abuse potential and induce neurotoxicity in rodents. Archives of toxicology. vol 95. issue 4. 2021-11-03. PMID:33515270. |
we also observed that 2c-c and 2c-p affected expression levels of the d1 dopamine receptor, d2 dopamine receptor, dopamine transporter, and phospho-dopamine transporter in the nucleus accumbens and the medial prefrontal cortex, and increased c-fos immuno-positive cells in the nucleus accumbens. |
2021-11-03 |
2023-08-13 |
mouse |
| Richard Quansah Amissah, Diellor Basha, Olga Bukhtiyarova, Elena Timofeeva, Igor Timofee. Neuronal activities during palatable food consumption in the reward system of binge-like eating female rats. Physiology & behavior. vol 242. 2021-11-03. PMID:34563545. |
in humans, bed is associated with desensitization of the reward system, specifically, the medial prefrontal cortex (mpfc), nucleus accumbens (acb), and ventral tegmental area (vta). |
2021-11-03 |
2023-08-13 |
rat |
| Zeinab Khastkhodaei, Muthuraman Muthuraman, Jenq-Wei Yang, Sergiu Groppa, Heiko J Luhman. Functional and directed connectivity of the cortico-limbic network in mice in vivo. Brain structure & function. vol 226. issue 3. 2021-11-02. PMID:33442810. |
central structures of this cortico-limbic network are ventral hippocampus (vhc), medial prefrontal cortex (pfc), basolateral amygdala (bla) and nucleus accumbens (nac). |
2021-11-02 |
2023-08-13 |
mouse |
| b' F Quessy, T Bittar, L J Blanchette, M L\\xc3\\xa9vesque, B Labont\\xc3\\xa. Stress-induced alterations of mesocortical and mesolimbic dopaminergic pathways. Scientific reports. vol 11. issue 1. 2021-10-29. PMID:34040100.' |
density of the mesolimbic and mesocortical projections was assessed via immuno-histochemistry combined with sholl analysis along with the staining of activity-dependent markers perk and c-fos in the ventral tegmental area (vta), nucleus accumbens (nac) and medial prefrontal cortex (mpfc). |
2021-10-29 |
2023-08-13 |
mouse |
| Anne T Park, Ursula A Tooley, Julia A Leonard, Austin L Boroshok, Cassidy L McDermott, M Dylan Tisdall, Allyson P Macke. Early childhood stress is associated with blunted development of ventral tegmental area functional connectivity. Developmental cognitive neuroscience. vol 47. 2021-10-13. PMID:33395612. |
work in animals has shown that early life stress has a profound impact on the ventral tegmental area (vta), which provides dopamine to regions including nucleus accumbens (nacc), anterior hippocampus, and medial prefrontal cortex (mpfc), with cascading effects over the course of development. |
2021-10-13 |
2023-08-13 |
Not clear |
| Limeng Huang, Yiwen Chen, Sen Jin, Li Lin, Shumin Duan, Ke Si, Wei Gong, J Julius Zh. Organizational principles of amygdalar input-output neuronal circuits. Molecular psychiatry. 2021-10-06. PMID:34400771. |
using a simplified cell-type- and projection-specific retrograde transsynaptic tracing technique, we scrutinized brain-wide afferent inputs of four major output neuronal groups in the amygdalar basolateral complex (bla) that project to the bed nucleus of the stria terminals (bnst), ventral hippocampus (vhpc), medial prefrontal cortex (mpfc) and nucleus accumbens (nac), respectively. |
2021-10-06 |
2023-08-13 |
Not clear |
| Leonardo A Guercio, Mathieu E Wimmer, Heath D Schmidt, Sarah E Swinford-Jackson, R Christopher Pierce, Fair M Vassole. Deep brain stimulation of the infralimbic cortex attenuates cocaine priming-induced reinstatement of drug seeking. Brain research. vol 1746. 2021-10-01. PMID:32652146. |
the present study investigated the effects of dbs in brain regions that send major glutamatergic projections to the nucleus accumbens including the basolateral amygdala (bla) and ventral hippocampus (vhipp) as well as subregions of the medial prefrontal cortex (mpfc) including the anterior cingulate, infralimbic and prelimbic cortices. |
2021-10-01 |
2023-08-13 |
rat |
| Claudia Rangel-Barajas, Israel Coronel, Yanping Zhang, Maribel Hernández, Stephen L Boehm I. Low-level developmental lead exposure does not predispose to adult alcohol self-administration, but does increase the risk of relapsing to alcohol seeking in mice: Contrasting role of GLT1 and xCT brain expression. Neuropharmacology. vol 181. 2021-09-23. PMID:33010299. |
because pb exposure is associated with increased glutamatergic tone, we also studied the effects on the expression of synaptic and non-synaptic glutamate transporters in brain regions associated with drug addiction such as the nucleus accumbens (nac), dorsomedial striatum (dms), dorsolateral striatum (dls), and medial prefrontal cortex (mpfc). |
2021-09-23 |
2023-08-13 |
mouse |
| Xueni Zhang, Yufeng Xun, Limin Wang, Jing Zhang, Wenjuan Hou, Huan Ma, Wenqi Cai, Laifu Li, Qianqian Guo, Yitong Li, Zijian Lv, Rui Jia, Fadao Tai, Zhixiong H. Involvement of the dopamine system in the effect of chronic social isolation during adolescence on social behaviors in male C57 mice. Brain research. vol 1765. 2021-09-21. PMID:33894223. |
chronic social isolation decreased levels of dopamine d2 receptor in the shell of the nucleus accumbens (nacc) and medial prefrontal cortex. |
2021-09-21 |
2023-08-13 |
mouse |
| Chenbo Wang, Chaofei Bao, Jiatao Gao, Yujin Gu, Xiao-Wei Don. Pain modulates neural responses to reward in the medial prefrontal cortex. Human brain mapping. vol 41. issue 5. 2021-09-16. PMID:31785068. |
whole-brain fmri analysis revealed that the main effect of outcome (win vs. loss) activated a typical network of the reward neural circuitry, including the medial prefrontal cortex (mpfc) and the bilateral nucleus accumbens (nacc). |
2021-09-16 |
2023-08-13 |
human |
| Matteo Marti, Giuseppe Talani, Cristina Miliano, Sabrine Bilel, Francesca Biggio, Jessica Bratzu, Marco Diana, Maria Antonietta De Luca, Liana Fattor. New insights into methoxetamine mechanisms of action: Focus on serotonergic 5-HT Experimental neurology. vol 345. 2021-09-07. PMID:34384790. |
is able to significantly alter serotonin levels in the rat medial prefrontal cortex (mpfc) and nucleus accumbens. |
2021-09-07 |
2023-08-13 |
mouse |
| Jie Li, Chen Lu, Zilong Gao, Yifan Feng, Huoqing Luo, Tangsheng Lu, Xia Sun, Ji Hu, Yanli Lu. SNRIs achieve faster antidepressant effects than SSRIs by elevating the concentrations of dopamine in the forebrain. Neuropharmacology. vol 177. 2021-08-12. PMID:32710978. |
in our study, a genetically encoded dopamine sensor and in vivo fiber photometry recordings were used to measure the dopamine concentrations in the medial prefrontal cortex (mpfc) and nucleus accumbens (nac) after acute intraperitoneal injection of ssris or snris. |
2021-08-12 |
2023-08-13 |
Not clear |
| Jennaya Christensen, Glenn R Yamakawa, Sabrina Salberg, Melinda Wang, Bryan Kolb, Richelle Mychasiu. Caffeine consumption during development alters spine density and recovery from repetitive mild traumatic brain injury in young adult rats. Synapse (New York, N.Y.). vol 74. issue 4. 2021-08-10. PMID:31705690. |
both caffeine and rmtbi increased spine density in the cg3 (medial prefrontal cortex [mpfc]), aid (orbitofrontal cortex [ofc]), and nucleus accumbens (nac), which is proposed to reflect an impairment in the normal pruning processes. |
2021-08-10 |
2023-08-13 |
rat |
| b' Thibault P Bittar, Mari Carmen Pelaez, Jose Cesar Hernandez Silva, Francis Quessy, Andr\\xc3\\xa9e-Anne Lavigne, Daphn\\xc3\\xa9e Morency, L\\xc3\\xa9a-Jeanne Blanchette, Eric Arsenault, Yoan Cherasse, Jos\\xc3\\xa9e Seigneur, Igor Timofeev, Chantelle F Sephton, Christophe D Proulx, Benoit Labont\\xc3\\xa. Chronic Stress Induces Sex-Specific Functional and Morphological Alterations in Corticoaccumbal and Corticotegmental Pathways. Biological psychiatry. vol 90. issue 3. 2021-08-10. PMID:33867113.' |
the medial prefrontal cortex (mpfc) is part of a complex circuit controlling stress responses by sending projections to different limbic structures including the nucleus accumbens (nac) and ventral tegmental area (vta). |
2021-08-10 |
2023-08-13 |
Not clear |
| Steven J Nieto, Colin N Haile, Cana B Quave, Mark J Harding, David A Nielsen, Richard A Meisch, Therese A Koste. Paternal alcohol exposure reduces acquisition of operant alcohol self-administration and affects Bdnf DNA methylation in male and female offspring. Addiction biology. 2021-08-07. PMID:34363290. |
dna methylation levels of the brain derived neurotrophic factor (bdnf) gene were measured in sperm, nucleus accumbens (nac) and medial prefrontal cortex (mpfc) in sires and in offspring. |
2021-08-07 |
2023-08-13 |
mouse |