| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Steven J Nieto, Colin N Haile, Cana B Quave, Mark J Harding, David A Nielsen, Richard A Meisch, Therese A Koste. Paternal alcohol exposure reduces acquisition of operant alcohol self-administration and affects Bdnf DNA methylation in male and female offspring. Addiction biology. 2021-08-07. PMID:34363290. |
dna methylation levels of the brain derived neurotrophic factor (bdnf) gene were measured in sperm, nucleus accumbens (nac) and medial prefrontal cortex (mpfc) in sires and in offspring. |
2021-08-07 |
2023-08-13 |
mouse |
| Vanessa Cristiane Santana Amaral, Gessynger Morais-Silva, Celina F Laverde, Marcelo T Mari. Susceptibility to extinction and reinstatement of ethanol-induced conditioned place preference is related to differences in astrocyte cystine-glutamate antiporter content. Neuroscience research. vol 170. 2021-08-04. PMID:32653617. |
thus, this study aimed to evaluate the relationship between the extinction and stress-induced reinstatement of ethanol conditioned place preference (cpp) and xct levels in the medial prefrontal cortex (mpfc), nucleus accumbens (nacc) and amygdala (amy). |
2021-08-04 |
2023-08-13 |
mouse |
| Mi Yang, Chang-Hao Luo, Ying-Qi Zhu, Yuan-Chu Liu, Ye-Juan An, Javed Iqbal, Zhe-Zhi Wang, Xin-Ming M. 7, 8-Dihydroxy-4-methylcoumarin reverses depression model-induced depression-like behaviors and alteration of dendritic spines in the mood circuits. Psychoneuroendocrinology. vol 119. 2021-07-21. PMID:32563935. |
the aim of this study was to investigate whether dhmc alleviates chronic unpredictable mild stress (cums)-induced depression-like behaviors and reverses cums-induced alterations in dendritic spines of principal neurons in brain areas of the emotional circuits including the hippocampus, medial prefrontal cortex (mpfc), nucleus accumbens (nac) and basolateral amygdala (bla) in male rats. |
2021-07-21 |
2023-08-13 |
rat |
| Mitra-Sadat Sadat-Shirazi, Haniyeh Soltani, Neda Nikpour, Masoud Haghshenas, Solmaz Khalifeh, Azarakhsh Mokri, Mohammad-Reza Zarrindas. Alteration of orexin-A and PKCα in the postmortem brain of pure-opioid and multi-drug abusers. Neuropeptides. vol 83. 2021-07-16. PMID:32741526. |
the medial prefrontal cortex (mpfc), lateral prefrontal cortex (lpfc), orbitofrontal cortex (ofc), nucleus accumbens (nac), and amygdala were dissected from fresh brain, frozen with liquid nitrogen and kept at -80 °c. |
2021-07-16 |
2023-08-13 |
Not clear |
| Andrew Chih Wei Huang, Ying Hao Yu, Alan Bo Han He, Chen Yin O. Interactions between prelimbic cortex and basolateral amygdala contribute to morphine-induced conditioned taste aversion in conditioning and extinction. Neurobiology of learning and memory. vol 172. 2021-07-14. PMID:32407964. |
the consequences of exciting or destroying the prelimbic cortex (prl) or the basolateral amygdala (bla) remain unclear, including the effects on morphine-induced conditioned taste aversion (cta) in the conditioning and extinction phases, plasma corticosterone (cort) levels, and c-fos/p-erk expressions in the subareas of the medial prefrontal cortex (i.e., prl, infralimbic cortex [il], cingulate cortex 1 [cg1]), basolateral amygdala (bla), central amygdala (cea), hippocampus (i.e., ca1, ca2, ca3, and dentate gyrus [dg]), nucleus accumbens (nac), lateral hypothalamus (lh), and piriform cortex (pc). |
2021-07-14 |
2023-08-13 |
Not clear |
| Gabriella Margetts-Smith, Anastasia I Macnaghten, Leonie S Brebner, Joseph J Ziminski, Meike C Sieburg, Jeffrey W Grimm, Hans S Crombag, Eisuke Koy. Acute, but not longer-term, exposure to environmental enrichment attenuates Pavlovian cue-evoked conditioned approach and Fos expression in the prefrontal cortex in mice. The European journal of neuroscience. vol 53. issue 8. 2021-06-29. PMID:33565633. |
we therefore measured the effects of acute/intermittent (1 day or 6 day of ee prior to test day) versus chronic (ee throughout conditioning lasting until test day) ee on the ability of a pavlovian sucrose cue to elicit sucrose seeking (conditioned approach) and fos expression in the medial prefrontal cortex (mpfc), orbitofrontal cortex (ofc), and nucleus accumbens (nac) in mice. |
2021-06-29 |
2023-08-13 |
mouse |
| Di Liu, Qian-Qian Tang, Di Wang, Su-Pei Song, Xiao-Na Yang, Su-Wan Hu, Zhi-Yong Wang, Zheng Xu, He Liu, Jun-Xia Yang, Sarah E Montgomery, Hongxing Zhang, Ming-Hu Han, Hai-Lei Ding, Jun-Li Ca. Mesocortical BDNF signaling mediates antidepressive-like effects of lithium. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 9. 2021-06-23. PMID:32428928. |
here, we demonstrated that the ventral tegmental area (vta) dopamine (da) neurons that project to the medial prefrontal cortex (mpfc), but not to nucleus accumbens (nac), contributed to the antidepressive-like effects of lithium. |
2021-06-23 |
2023-08-13 |
mouse |
| Lauren C Smith, Marsida Kallupi, Lani Tieu, Kokila Shankar, Abigail Jaquish, Jamie Barr, Yujuan Su, Nathan Velarde, Sharona Sedighim, Lieselot L G Carrette, Mike Klodnicki, Xin Sun, Giordano de Guglielmo, Olivier Georg. Validation of a nicotine vapor self-administration model in rats with relevance to electronic cigarette use. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 11. 2021-06-23. PMID:32544927. |
finally, 3 weeks of daily (1 h) nicotine vapor self-administration produced cardiopulmonary abnormalities and changes in α4, α3, and β2 nicotinic acetylcholine receptor subunit mrna levels in the nucleus accumbens and medial prefrontal cortex. |
2021-06-23 |
2023-08-13 |
rat |
| Miguel Skirzewski, Marie E Cronin, Ricardo Murphy, Wambura Fobbs, Alexxai V Kravitz, Andres Buonann. ErbB4 Null Mice Display Altered Mesocorticolimbic and Nigrostriatal Dopamine Levels as well as Deficits in Cognitive and Motivational Behaviors. eNeuro. vol 7. issue 3. 2021-06-18. PMID:32354758. |
here, we report that extracellular steady-state levels of da are reduced in the medial prefrontal cortex (mpfc; -65%), hippocampus (-53%) and nucleus accumbens (nac; -35%), but are elevated in the dorsal striatum (+25%) of erbb4 knock-out mice (erbb4 kos) relative to wild-type controls. |
2021-06-18 |
2023-08-13 |
mouse |
| Gang Lei, Fei Liu, Peng Liu, Tong Jiao, Liu Yang, Zheng Chu, Li-Sha Deng, Yan Li, Yong-Hui Dan. Does genetic mouse model of constitutive Hint1 deficiency exhibit schizophrenia-like behaviors? Schizophrenia research. vol 222. 2021-06-17. PMID:32439293. |
total glutamate was decreased in the medial prefrontal cortex, nucleus accumbens (nac), and hip of ko mice. |
2021-06-17 |
2023-08-13 |
mouse |
| Vivien Csikós, Petra Varró, Veronika Bódi, Szilvia Oláh, Ildikó Világi, Arpád Doboly. The mycotoxin deoxynivalenol activates GABAergic neurons in the reward system and inhibits feeding and maternal behaviours. Archives of toxicology. vol 94. issue 9. 2021-06-16. PMID:32472169. |
don injection resulted in profound c-fos activation in only the elements of the reward system, such as the accumbens nucleus, the medial prefrontal cortex, and the ventral tegmental area. |
2021-06-16 |
2023-08-13 |
mouse |
| José Pedro Prieto, Ximena López Hill, Jessika Urbanavicius, Verónica Sanchez, Xavier Nadal, Cecilia Scorz. Cannabidiol Prevents the Expression of the Locomotor Sensitization and the Metabolic Changes in the Nucleus Accumbens and Prefrontal Cortex Elicited by the Combined Administration of Cocaine and Caffeine in Rats. Neurotoxicity research. vol 38. issue 2. 2021-06-14. PMID:32415526. |
the effect of cbd on putative alterations in the metabolic activity of the medial prefrontal cortex (mpfc) and nucleus accumbens (nac), and its respective subregions (cingulated, prelimbic, and infralimbic cortices, and nac core and shell) associated to the behavioral response, was also investigated. |
2021-06-14 |
2023-08-13 |
rat |
| Pamela DeRosse, Anita D Barbe. Overlapping Neurobiological Substrates for Early-Life Stress and Resilience to Psychosis. Biological psychiatry. Cognitive neuroscience and neuroimaging. vol 6. issue 2. 2021-06-03. PMID:33097471. |
exposure to early-life stress disrupts the neurodevelopment of widespread brain systems, including key components of the hypothalamic-pituitary-adrenal axis stress response, such as the amygdala, hippocampus, and medial prefrontal cortex, as well as key components of the brain's reward system, such as the nucleus accumbens and orbitofrontal cortex. |
2021-06-03 |
2023-08-13 |
Not clear |
| Sara Emi M M Ferreira, Leonardo M Soares, Clarice R Lira, Thais S Yokoyama, Sheila A Engi, Fábio C Cruz, Rodrigo M Leã. Ethanol-induced locomotor sensitization: Neuronal activation in the nucleus accumbens and medial prefrontal cortex. Neuroscience letters. vol 749. 2021-06-03. PMID:33610663. |
in another group of animals, we performed the quantitative analysis of the arc and psd-95 protein levels by western blotting in the medial prefrontal cortex and nucleus accumbens brain areas. |
2021-06-03 |
2023-08-13 |
mouse |
| Sara Emi M M Ferreira, Leonardo M Soares, Clarice R Lira, Thais S Yokoyama, Sheila A Engi, Fábio C Cruz, Rodrigo M Leã. Ethanol-induced locomotor sensitization: Neuronal activation in the nucleus accumbens and medial prefrontal cortex. Neuroscience letters. vol 749. 2021-06-03. PMID:33610663. |
furthermore, the ethanol pretreatment reduced arc expression in the nucleus accumbens and medial prefrontal cortex. |
2021-06-03 |
2023-08-13 |
mouse |
| M J Castelhano-Carlos, S Aslani, N Sous. The Impact of Physical Enrichment in the Structure of the Medial Prefrontal Cortex and Nucleus Accumbens of the Adult Male Rat Brain. Neuroscience. vol 454. 2021-05-14. PMID:32058067. |
herein, we assessed neuronal plasticity as a consequence of living in the phw, by comparing the structure of the medial prefrontal cortex (mpfc) and the nucleus accumbens (nac), two brain areas involved in the circuitry regulating motivation and reward. |
2021-05-14 |
2023-08-13 |
rat |
| Katsumasa Muneoka, Yasunori Oda, Masaaki Iwata, Masaomi Iyo, Kenji Hashimoto, Yukihiko Shirayam. Monoaminergic balances predict non-depression-like phenotype in Learned Helplessness Paradigm. Neuroscience. vol 440. 2021-05-14. PMID:32222554. |
here, we measured the levels of monoamines, including noradrenaline (na), serotonin (5-ht), and dopamine (da), and their metabolites in the medial prefrontal cortex (mpfc), orbitofrontal cortex (ofc), hippocampus, nucleus accumbens (nac), amygdala, and striatum in lh, non-lh, and non-manipulated (naïve) rats. |
2021-05-14 |
2023-08-13 |
rat |
| Luis A- Trujillo Villarreal, Marcela Cárdenas-Tueme, Roger Maldonado-Ruiz, Diana Reséndez-Pérez, Alberto Camacho-Morale. Potential role of primed microglia during obesity on the mesocorticolimbic circuit in autism spectrum disorder. Journal of neurochemistry. vol 156. issue 4. 2021-05-04. PMID:32902852. |
studies employing structural and functional magnetic resonance imaging reported morphological and functional abnormalities in the connectivity of the mesocorticolimbic reward pathway between the nucleus accumbens and the ventral tegmental area (vta) in response to social stimuli, as well as diminished medial prefrontal cortex in response to visual cues, whereas stronger reward system responses for the non-social realm (e.g., video games) than social rewards (e.g., approval), associated with caudate nucleus responsiveness in asd children. |
2021-05-04 |
2023-08-13 |
mouse |
| Ana Margarida Cunha, Marco Rafael Guimarães, Nikolaos Kokras, Ioannis Sotiropoulos, Nuno Sousa, Armando Almeida, Christina Dalla, Hugo Leite-Almeid. Mesocorticolimbic monoamines in a rodent model of chronic neuropathic pain. Neuroscience letters. vol 737. 2021-04-30. PMID:32818589. |
in this study, we analyzed the levels of monoamines dopamine (da), noradrenaline (na) and serotonin (5-ht) in mesocorticolimbic areas - medial prefrontal cortex, orbitofrontal cortex, striatum, nucleus accumbens and amygdala - 1 month after a neuropathic lesion, spared nerve injury (sni). |
2021-04-30 |
2023-08-13 |
Not clear |
| Rebecca S Hofford, Tanner J Euston, Rashaun S Wilson, Katherine R Meckel, Emily G Peck, Arthur Godino, Joseph A Landry, Erin S Calipari, TuKiet T Lam, Drew D Kiral. Granulocyte-Colony Stimulating Factor Reduces Cocaine-Seeking and Downregulates Glutamatergic Synaptic Proteins in Medial Prefrontal Cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 7. 2021-04-29. PMID:33361463. |
quantitative assessment of changes in the proteomic landscape in the nucleus accumbens (nac) and medial prefrontal cortex (mpfc) were performed via data-independent acquisition (dia) mass spectrometry analysis. |
2021-04-29 |
2023-08-13 |
rat |