| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Erica A Cross, Kim L Huhman, H Elliott Alber. Sex differences in the impact of social status on social reward and associated mesolimbic activation. Physiology & behavior. 2023-11-17. PMID:37977252. |
in a second experiment, we found more activation of the mesolimbic dopamine system (mds) as assessed with cfos immunohistochemistry in the lateral ventral tegmental area (lvta) and the nucleus accumbens (nac) shell of male winners compared to losers. |
2023-11-17 |
2023-11-20 |
Not clear |
| Jamie C Moffa, India N Bland, Jessica R Tooley, Vani Kalyanaraman, Monique Heitmeier, Meaghan C Creed, Bryan A Copit. Cell specific single viral vector CRISPR/Cas9 editing and genetically encoded tool delivery in the central and peripheral nervous systems. bioRxiv : the preprint server for biology. 2023-10-24. PMID:37873336. |
we tested these tools in multiple brain regions and cell types, including gabaergic neurons in the nucleus accumbens (nac), glutamatergic neurons projecting from the ventral pallidum (vp) to the lateral habenula (lhb), dopaminergic neurons in the ventral tegmental area (vta), and parvalbumin (pv)-positive proprioceptive neurons in the periphery. |
2023-10-24 |
2023-11-08 |
mouse |
| Pang-Ning Teng, Waleed Barakat, Sophie M Tran, Zoe M Tran, Nicholas W Bateman, Kelly A Conrads, Katlin N Wilson, Julie Oliver, Glenn Gist, Brian L Hood, Ming Zhou, G Larry Maxwell, Lorenzo Leggio, Thomas P Conrads, Mary R Le. Brain proteomic atlas of alcohol use disorder in adult males. Translational psychiatry. vol 13. issue 1. 2023-10-13. PMID:37833300. |
we performed a quantitative proteomic analysis using a liquid chromatography-tandem mass spectrometry (lc-ms/ms) analysis of human postmortem tissue from brain regions that play key roles in the development and maintenance of aud, the amygdala (amg), hippocampus (hipp), hypothalamus (hyp), nucleus accumbens (nac), prefrontal cortex (pfc) and ventral tegmental area (vta). |
2023-10-13 |
2023-10-15 |
human |
| Gavin C Jones, Christina A Small, Dallin Z Otteson, Caylor W Hafen, Jacob T Breinholt, Paul D Flora, Matthew D Burris, David W Sant, Tysum R Ruchti, Jordan T Yorgason, Scott C Steffensen, Kyle B Bill. Whole-Body Vibration Prevents Neuronal, Neurochemical, and Behavioral Effects of Morphine Withdrawal in a Rat Model. International journal of molecular sciences. vol 24. issue 18. 2023-09-28. PMID:37762450. |
peripheral mechanoreceptor-based treatments such as acupuncture and chiropractic manipulation have shown success in modulating the mesolimbic dopamine (da) system originating in the ventral tegmental area (vta) of the midbrain and projecting to the nucleus accumbens (nac) of the striatum. |
2023-09-28 |
2023-10-07 |
rat |
| Young Woo Noh, Yangsik Kim, Soowon Lee, Yeonghyeon Kim, Jae Jin Shin, Hyojin Kang, Il Hwan Kim, Eunjoon Ki. The PFC-LH-VTA pathway contributes to social deficits in IRSp53-mutant mice. Molecular psychiatry. 2023-09-21. PMID:37730842. |
dopamine (da) neurons in the ventral tegmental area (vta) promote social brain functions by releasing da onto nucleus accumbens neurons, but it remains unclear how vta neurons communicate with cortical neurons. |
2023-09-21 |
2023-10-07 |
mouse |
| Su-Bin Hwang, Jae-Gyeong Lee, Youyoung Lee, Wun-A Kook, Seon-Kyung Kim, Audrey Lynn Donio, Hee-Won Min, Young-Jung Kim, Seok-Yong Lee, Choon-Gon Jan. Adinazolam, a Benzodiazepine-Type New Psychoactive Substance, Has Abuse Potential and Induces Withdrawal Symptoms in Rodents. ACS chemical neuroscience. 2023-09-11. PMID:37695876. |
after the ivsa test, an enzyme-linked immunosorbent assay (elisa) showed that adz administration significantly increased the dopamine contents in the thalamus, nucleus accumbens (nac), and ventral tegmental area (vta). |
2023-09-11 |
2023-10-07 |
mouse |
| Nora H Prior, Chelsea M Haakenson, Savannah Clough, Gregory F Ball, Benjamin A Sandka. Varied impacts of social relationships on neuroendocrine state. Hormones and behavior. vol 155. 2023-09-07. PMID:37678093. |
we defined neuroendocrine state by the expression of 22 genes related to 4 major signaling pathways (dopamine, steroid, nonapeptide, and opioid) in six brain regions associated with affiliation or communication [nucleus accumbens (nac), nucleus taeniae of the amygdala (tna), medial preoptic area (pom), and periaqueductal gray (pag), ventral tegmental area, and auditory cortex]. |
2023-09-07 |
2023-10-07 |
Not clear |
| Margaret P Schmill, Zoe Thompson, Daisy Lee, Laurence Haddadin, Shaarang Mitra, Raymond Ezzat, Samantha Shelton, Phillip Levin, Sogol Behnam, Kelly J Huffman, Theodore Garlan. Hippocampal, whole midbrain, red nucleus, and ventral tegmental area volumes are increased by selective breeding for high voluntary wheel-running behavior. Brain, behavior and evolution. 2023-08-21. PMID:37604130. |
neither linetype nor wheel access affected volumes of the substantia nigra (sn), ventral tegmental area (vta), nucleus accumbens (nac), ventral pallidum (vp) or basolateral amygdala (bla). |
2023-08-21 |
2023-09-07 |
mouse |
| Désirée R Seib, Daniel J Tobiansky, John Meitzen, Stan B Floresco, Kiran K Som. Neurosteroids and the mesocorticolimbic system. Neuroscience and biobehavioral reviews. 2023-08-11. PMID:37567491. |
this circuit includes dopaminergic projections from the ventral tegmental area to the nucleus accumbens and medial prefrontal cortex. |
2023-08-11 |
2023-08-16 |
Not clear |
| Samah Shahen-Zoabi, Reem Smoum, Alexey Bingor, Etty Grad, Alina Nemirovski, Tawfeeq Shekh-Ahmad, Raphael Mechoulam, Rami Yak. N-oleoyl glycine and N-oleoyl alanine attenuate alcohol self-administration and preference in mice. Translational psychiatry. vol 13. issue 1. 2023-07-31. PMID:37524707. |
we first measured the ecbs and ecb-ls levels in different brain reward system regions following chronic alcohol self-administration using lc-ms. we have found that following chronic intermittent alcohol consumption, n-oleoyl glycine (olgly) levels were significantly elevated in the prefrontal cortex (pfc), and n-oleoyl alanine (olala) was significantly elevated in the pfc, nucleus accumbens (nac) and ventral tegmental area (vta) in a region-specific manner. |
2023-07-31 |
2023-08-14 |
mouse |
| Michael W Gongwer, Cassandra B Klune, João Couto, Benita Jin, Alexander S Enos, Rita Chen, Drew Friedmann, Laura A DeNard. Brain-wide projections and differential encoding of prefrontal neuronal classes underlying learned and innate threat avoidance. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-07-25. PMID:37491314. |
using tissue clearing and light sheet fluorescence microscopy, we mapped the brain-wide axon collaterals of populations of mpfc neurons that project to nucleus accumbens (nac), ventral tegmental area (vta), or contralateral mpfc (cmpfc). |
2023-07-25 |
2023-08-14 |
mouse |
| Joakim W Ronström, Stephanie B Williams, Andrew Payne, Daniel J Obray, Caylor Hafen, Matthew Burris, K Scott Weber, Scott C Steffensen, Jordan T Yorgaso. Interleukin-10 enhances activity of ventral tegmental area dopamine neurons resulting in increased dopamine release. Brain, behavior, and immunity. 2023-07-15. PMID:37453452. |
dopamine transmission from the ventral tegmental area (vta) to the nucleus accumbens (nac) regulates important aspects of motivation and is influenced by the neuroimmune system. |
2023-07-15 |
2023-08-14 |
Not clear |
| Xiao Cui, Qiuping Tong, Hao Xu, Chuantong Xie, Lei Xia. A putative loop connection between VTA dopamine neurons and nucleus accumbens encodes positive valence to compensate for hunger. Progress in neurobiology. 2023-07-14. PMID:37451329. |
a putative loop connection between vta dopamine neurons and nucleus accumbens encodes positive valence to compensate for hunger. |
2023-07-14 |
2023-08-14 |
mouse |
| Dillon J McGovern, Abigail M Polter, Emily D Prévost, Annie Ly, Connor J McNulty, Bodhi Rubinstein, David H Roo. Ventral tegmental area glutamate neurons establish a mu-opioid receptor gated circuit to mesolimbic dopamine neurons and regulate opioid-seeking behavior. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-07-05. PMID:37407648. |
this vta glutamate to vta dopamine pathway regulated dopamine release to the nucleus accumbens through mu-opioid receptor activity in vivo. |
2023-07-05 |
2023-08-14 |
mouse |
| Astrid M Cardona-Acosta, Omar K Sial, Lyonna F Parise, Tamara Gnecco, Giselle Enriquez Marti, Carlos A Bolaños-Guzmá. Alprazolam exposure during adolescence induces long-lasting dysregulation in reward sensitivity to morphine and second messenger signaling in the VTA-NAc pathway. Scientific reports. vol 13. issue 1. 2023-07-05. PMID:37407659. |
in a separate experiment, mice received alp (0, 0.5 mg/kg) and then sacrificed 24-h or 1-month after treatment to assess levels of extracellular signal regulated kinase 1/2 (erk1/2) gene expression, protein phosphorylation, and downstream targets (creb, akt) within the ventral tegmental area (vta) and nucleus accumbens (nac). |
2023-07-05 |
2023-08-14 |
mouse |
| Jimmy Olusakin, Gautam Kumar, Mahashweta Basu, Cali A Calarco, Megan E Fox, Jason B Alipio, Catherine Haga, Makeda D Turner, Asaf Keller, Seth A Ament, Mary Kay Lob. Transcriptomic profiling of reward and sensory brain areas in perinatal fentanyl exposed juvenile mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-07-03. PMID:37400565. |
rna was extracted from nucleus accumbens (nac), prelimbic cortex (prl), ventral tegmental area (vta), somatosensory cortex (s1) and ventrobasal thalamus (vbt) from perinatal fentanyl exposed mice of both sexes at p35. |
2023-07-03 |
2023-08-14 |
mouse |
| Jeong Pyo Seo, Heun Jae Ry. Neural Injury of the Dopaminergic Pathways in Patients with Middle Cerebral Artery Territory Infarct: A Diffusion Tensor Imaging Study. Brain sciences. vol 13. issue 6. 2023-06-28. PMID:37371405. |
the mesocortical tract (mct) and mesolimbic tract (mlt), dopaminergic pathways originating from the ventral tegmental area in the midbrain to the ventral striatum (nucleus accumbens) and prefrontal cortex, play a crucial role in regulating incentive salience. |
2023-06-28 |
2023-08-14 |
Not clear |
| Alyse N Maksimoski, Sharon A Stevenson, Brandon J Polzin, Changjiu Zhao, Elsa M Luebke, Lauren V Riter. The motivation to flock correlates with vocal-social behaviors and dopamine-related gene expression in male European starlings. Hormones and behavior. vol 153. 2023-06-04. PMID:37271085. |
the nucleus accumbens (nac), medial preoptic area (pom), and ventral tegmental area (vta) are implicated in vocal-social behaviors in flocks, including singing. |
2023-06-04 |
2023-08-14 |
Not clear |
| Ruijie Jin, Shanbin Sun, Yang Hu, Hongfei Zhang, Xiangrong Su. Neuropeptides Modulate Feeding via the Dopamine Reward Pathway. Neurochemical research. 2023-05-26. PMID:37233918. |
the reward system comprises the ventral tegmental area (vta), nucleus accumbens (nac), hypothalamus, and limbic system. |
2023-05-26 |
2023-08-14 |
Not clear |
| Anna I Dunigan, Aaron G Roseberr. Actions of feeding-related peptides on the mesolimbic dopamine system in regulation of natural and drug rewards. Addiction neuroscience. vol 2. 2023-05-23. PMID:37220637. |
in this review, we summarize the effects of a selected set of feeding-related peptides and hormones acting within the ventral tegmental area and nucleus accumbens to alter feeding, as well as food, drug, and social reward. |
2023-05-23 |
2023-08-14 |
Not clear |