| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Svetlana Bryant, Julie-Anne Balouek, Luke T Geiger, David J Barker, Catherine J Peñ. Neuropathic pain as a trigger for histone modifications in limbic circuitry. Genes, brain, and behavior. 2022-11-22. PMID:36412100. |
to better understand how such enduring transcriptional changes might be regulated within brain structures associated with processing of pain or affect, we examined epigenetic modifications involved with active or permissive transcriptional states (histone h3 lysine 4 mono and trimethylation, and histone h3 lysine 27 acetylation) in periaqueductal gray (pag), lateral hypothalamus (lh), nucleus accumbens (nac), and ventral tegmental area (vta) 5 weeks after sciatic nerve injury in mice to model chronic pain. |
2022-11-22 |
2023-08-14 |
mouse |
| Eric J Nunes, Nii A Add. L-type calcium channel regulation of dopamine activity in the ventral tegmental area to nucleus accumbens pathway: Implications for substance use, mood disorders and co-morbidities. Neuropharmacology. 2022-11-22. PMID:36414149. |
l-type calcium channel regulation of dopamine activity in the ventral tegmental area to nucleus accumbens pathway: implications for substance use, mood disorders and co-morbidities. |
2022-11-22 |
2023-08-14 |
Not clear |
| Wanqi Che. Neural circuits provide insights into reward and aversion. Frontiers in neural circuits. vol 16. 2022-11-17. PMID:36389177. |
the aim of this paper is to summarize the latest findings on the mechanisms of the neural circuits associated with reward and aversion in a review of previous studies with a focus on the ventral tegmental area (vta), nucleus accumbens (nac), and basal forebrain (bf). |
2022-11-17 |
2023-08-14 |
Not clear |
| Jakkrit Nukitram, Ekkasit Kumarnsit, Dania Cheah. A 1:1 ratio of cannabidiol: tetrahydrocannabinol attenuates methamphetamine conditioned place preference in mice: A prospective study of antidopaminergic mechanism. Brain research bulletin. 2022-11-06. PMID:36336144. |
male icr mice were implanted with the lfp electrode in the ventral tegmental area (vta) and the nucleus accumbens (nac). |
2022-11-06 |
2023-08-14 |
mouse |
| Kyle B Bills, Dallin Z Otteson, Gavin C Jones, James N Brundage, Emily K Baldwin, Christina A Small, Hee Young Kim, Jordan T Yorgason, Jonathan D Blotter, Scott C Steffense. Mechanical Stimulation Alters Chronic Ethanol-Induced Changes to VTA GABA Neurons, NAc DA Release and Measures of Withdrawal. International journal of molecular sciences. vol 23. issue 20. 2022-10-27. PMID:36293482. |
it has been previously shown to modulate the firing rate of neurons in the ventral tegmental area (vta) and dopamine (da) release in the nucleus accumbens (nac), an area of interest in alcohol-use disorder (aud). |
2022-10-27 |
2023-08-14 |
rat |
| Soo Min Lee, Han Byeol Jang, Yu Fan, Bonghyo Lee, Sang Chan Kim, Kyle B Bills, Scott C Steffensen, Hee Young Ki. Nociceptive stimuli activate the hypothalamus-habenula circuit to inhibit the mesolimbic reward system and cocaine seeking-behaviors. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-10-24. PMID:36280259. |
tail-pinch increased activity of gaba neurons in ventral tegmental area (vta), decreased extracellular da level in the nucleus accumbens ventrolateral shell in intact rats and reduced cocaine-increased da concentration, which was blocked by disruption of the lh. |
2022-10-24 |
2023-08-14 |
rat |
| Hiroyuki Arakaw. Dynamic regulation of oxytocin neuronal circuits in the sequential processes of prosocial behavior in rodent models. Current research in neurobiology. vol 2. 2022-10-17. PMID:36246512. |
here, the author discusses recent evidence illustrating the functioning of ot neural circuits in the processing of multimodal components of social behavior, including the detection/recognition of social cues via the olfactory bulb through olfactory cortices, evaluation of social features via the circuits of the paraventricular nucleus of the hypothalamus to the medial amygdala, and maintenance of prosocial behaviors via the circuits of the ventral tegmental area to the nucleus accumbens. |
2022-10-17 |
2023-08-14 |
mouse |
| Kolter Grigsby, Courtney Ledford, Tanvi Batish, Snigdha Kanadibhotla, Delaney Smith, Evan Firsick, Alexander Tran, Kayla Townsley, Kaylee-Abril Vasquez Reyes, Katherine LeBlanc, Angela Ozbur. Targeting the Maladaptive Effects of Binge Drinking on Circadian Gene Expression. International journal of molecular sciences. vol 23. issue 19. 2022-10-14. PMID:36232380. |
therefore, the present study sought to test the effects of chronic binge-like drinking on diurnal circadian gene expression patterns in the master circadian pacemaker (scn), the ventral tegmental area (vta), and the nucleus accumbens (nac) in high drinking in the dark-1 (hdid-1) mice, a unique genetic risk model for drinking to intoxication. |
2022-10-14 |
2023-08-14 |
mouse |
| Xinjian Zhang, Daisuke Tsuboi, Yasuhiro Funahashi, Yukie Yamahashi, Kozo Kaibuchi, Taku Naga. Phosphorylation Signals Downstream of Dopamine Receptors in Emotional Behaviors: Association with Preference and Avoidance. International journal of molecular sciences. vol 23. issue 19. 2022-10-14. PMID:36232945. |
dopamine regulates emotional behaviors, including rewarding and aversive behaviors, through the mesolimbic dopaminergic pathway, which projects dopamine neurons from the ventral tegmental area to the nucleus accumbens (nac). |
2022-10-14 |
2023-08-14 |
Not clear |
| Tong-Yu Liang, Hua Zhou, Yan-Gang Su. Distinct roles of dopamine receptor subtypes in the nucleus accumbens during itch signal processing. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2022-10-14. PMID:36241382. |
ventral tegmental area (vta) dopaminergic neurons, which are well known for their central roles in reward and motivation-related behaviors, have been shown to participate in itch processing via their projection to the nucleus accumbens (nac). |
2022-10-14 |
2023-08-14 |
mouse |
| Ashley J McFalls, Christopher Jenney, Rachel S Stanford, Emma Woodward, Andras Hajnal, Patricia S Grigson, Kent E Vran. Greater Avoidance of a Saccharin Cue Paired with Passive Delivery of Heroin is Associated with a Select Increase in Expression of CRFR2 and CRFbp in the Hippocampus in Rats. Brain research bulletin. 2022-10-13. PMID:36228871. |
we then assessed gene expression for components of the crf pathway in the mpfc, hipp, vta, amygdala, and nucleus accumbens (nac). |
2022-10-13 |
2023-08-14 |
rat |
| Rossy Olivares-Barraza, José Luis Marcos, Jonathan Martínez-Pinto, Marco Fuenzalida, Javier A Bravo, Katia Gysling, Ramón Sotomayor-Zárat. Corticotropin-releasing factor system in the lateral septum: Implications in the pathophysiology of obesity. Frontiers in molecular neuroscience. vol 15. 2022-10-07. PMID:36204135. |
brain areas, like the lateral hypothalamus (lh), ventral tegmental area (vta), and nucleus accumbens (nacc) have been linked in both homeostatic and hedonic control of feeding in experimental models of diet-induced obesity. |
2022-10-07 |
2023-08-14 |
Not clear |
| Kobra Askari, Shahrbanoo Oryan, Akram Eidi, Jalal Zaringhalam, Abbas Haghparas. Blockade of the orexin receptors in the ventral tegmental area could attenuate the stress-induced analgesia: A behavioral and molecular study. Progress in neuro-psychopharmacology & biological psychiatry. 2022-09-18. PMID:36116673. |
the current study examined the modulatory role of the ventral tegmental area (vta) orexinergic system in the restraint sia and extracellular signal-regulated kinase (erk) activation in the nucleus accumbens (nac). |
2022-09-18 |
2023-08-14 |
rat |
| Noelia Cantero-García, Antonio Flores-Burgess, Juan Pedro Pineda-Gómez, Laura Orio, Antonia Serrano, Zaida Díaz-Cabiale, Carmelo Milló. Galanin N-terminal fragment (1-15) reduces alcohol seeking and alcohol relapse in rats: Involvement of mesocorticolimbic system. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 153. 2022-09-09. PMID:36076594. |
notably, the mechanism of gal(1-15)-mediated actions involved changes in c-fos, dopamine receptors and 5ht1a expression in the ventral tegmental area, accumbens nucleus and prefrontal cortex. |
2022-09-09 |
2023-08-14 |
rat |
| Ákos Babiczky, Ferenc Matya. Molecular characteristics and laminar distribution of prefrontal neurons projecting to the mesolimbic system. eLife. vol 11. 2022-09-05. PMID:36063145. |
prefrontal cortical influence over the mesolimbic system - including the nucleus accumbens (nac) and the ventral tegmental area (vta) - is implicated in various cognitive processes and behavioral malfunctions. |
2022-09-05 |
2023-08-14 |
mouse |
| Yanning Zuo, Attilio Iemolo, Patricia Montilla-Perez, Hai-Ri Li, Xia Yang, Francesca Teles. Chronic adolescent exposure to cannabis in mice leads to sex-biased changes in gene expression networks across brain regions. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2022-08-22. PMID:35995972. |
the cognitive modules were related to endocannabinoid signaling in the female dorsal medial striatum, inflammation in the female ventral tegmental area, and synaptic transmission in the male nucleus accumbens. |
2022-08-22 |
2023-08-14 |
mouse |
| Ana Verónica Domingues, Bárbara Coimbra, Raquel Correia, Catarina Deseyve, Natacha Vieitas-Gaspar, Stan B Floresco, Nuno Sousa, Carina Soares-Cunha, Ana João Rodrigue. Prenatal dexamethasone exposure alters effort decision making and triggers nucleus accumbens and anterior cingulate cortex functional changes in male rats. Translational psychiatry. vol 12. issue 1. 2022-08-19. PMID:35986000. |
different brain regions coordinate this complex decision, including the nucleus accumbens (nac), anterior cingulate cortex (acc), and ventral tegmental area (vta). |
2022-08-19 |
2023-08-14 |
rat |
| Kathrin C J Eschmann, Duarte F M M Pereira, Ashvanti Valji, Vera Dehmelt, Matthias J Grube. Curiosity and Mesolimbic Functional Connectivity Drive Information Seeking in Real Life. Social cognitive and affective neuroscience. 2022-08-17. PMID:35975900. |
additionally, the frequency of information seeking was predicted by individual differences in resting-state functional connectivity between the ventral tegmental area and the nucleus accumbens. |
2022-08-17 |
2023-08-14 |
human |
| J Daniel Obray, Christina A Small, Emily K Baldwin, Eun Young Jang, Jin Gyeom Lee, Chae Ha Yang, Jordan T Yorgason, Scott C Steffense. Dopamine D2-Subtype Receptors Outside the Blood-Brain Barrier Mediate Enhancement of Mesolimbic Dopamine Release and Conditioned Place Preference by Intravenous Dopamine. Frontiers in cellular neuroscience. vol 16. 2022-07-29. PMID:35903367. |
following administration of intravenous dopamine, the firing rate of putative da neurons in the vta displayed a biphasic response and da levels in the nucleus accumbens were enhanced. |
2022-07-29 |
2023-08-14 |
Not clear |
| Angela R Bongiovanni, Pingwei Zhao, Saadet Inan, Sonita Wiah, Aryan Shekarabi, Daniel J Farkas, Mia N Watson, Mathieu E Wimmer, Michael R Ruff, Scott M Rawl. Multi-chemokine receptor antagonist RAP-103 inhibits opioid-derived respiratory depression, reduces opioid reinforcement and physical dependence, and normalizes opioid-induced dysregulation of mesolimbic chemokine receptors in rats. Drug and alcohol dependence. vol 238. 2022-07-17. PMID:35843139. |
ccr2 and cxcr4 were increased in the ventral tegmental area (vta), whereas ccr2 and ccr5 were reduced in the nucleus accumbens (nac). |
2022-07-17 |
2023-08-14 |
rat |