| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhengjie Yang, Yijie Xie, Kaixin Dou, Liying Yang, Anmu Xi. Associations of striatal dopamine transporter binding with motor and non-motor symptoms in early Parkinson's disease. Clinical and translational science vol issue 2023 36915231 |
dopamine transporter (dat) imaging is an in vivo tool to assess presynaptic dopaminergic function in the clinical practices of parkinson's disease (pd). |
2023-03-14 |
2023-04-07 |
Not clear |
| Zhengjie Yang, Yijie Xie, Kaixin Dou, Liying Yang, Anmu Xi. Associations of striatal dopamine transporter binding with motor and non-motor symptoms in early Parkinson's disease. Clinical and translational science vol issue 2023 36915231 |
our findings clarified quantitative associations between certain motor and non-motor features with current and future striatal dopamine binding, suggesting the feasibility of using dat images as a progression predictive marker for pd. |
2023-03-14 |
2023-04-07 |
Not clear |
| Xiao-Na Zhu, Jie Li, Gao-Lin Qiu, Lin Wang, Chen Lu, Yi-Ge Guo, Ke-Xin Yang, Fang Cai, Tao Xu, Ti-Fei Yuan, Ji H. Propofol exerts anti-anhedonia effects via inhibiting the dopamine transporter. Neuron vol issue 2023 36917979 |
here, we report that propofol actively and directly binds to the dopamine transporter (dat), but not the serotonin transporter (sert), which contributes to the rapid relief of anhedonia. |
2023-03-14 |
2023-04-07 |
mouse |
| X Zhang, M S Berridge, S M Apana, W Slikker, M G Paule, John Talpo. Discontinuation of methylphenidate after long-term exposure in nonhuman primates. Neurotoxicology and teratology vol issue 2023 36893929 |
the blockage of the dopamine transporter (dat) and the norepinephrine transporter (net) by mph may help with adhd symptoms by boosting monoamine levels in the synapse. |
2023-03-09 |
2023-04-07 |
human |
| Ryoji Goto, Masanori Kurihara, Masashi Kameyama, Hiroki Komatsu, Masashi Higashino, Keiko Hatano, Ryoko Ihara, Mana Higashihara, Yasushi Nishina, Tomoyasu Matsubara, Kazutomi Kanemaru, Yuko Saito, Shigeo Murayama, Atsushi Iwat. Correlations between cerebrospinal fluid homovanillic acid and dopamine transporter SPECT in degenerative parkinsonian syndromes. Journal of neural transmission (Vienna, Austria : 1996) vol issue 2023 36871130 |
both cerebrospinal fluid (csf) homovanillic acid (hva) and striatal dopamine transporter (dat) binding on single-photon emission computed tomography (spect) reflect nigrostriatal dopaminergic function, but studies on the relationship between the two have been limited. |
2023-03-04 |
2023-03-06 |
human |
| Mohamed El Fadili, Mohammed Er-Rajy, Hamada Imtara, Omar M Noman, Ramzi A Mothana, Sheaf Abdullah, Sara Zerougui, Menana Elhallaou. QSAR, ADME-Tox, molecular docking and molecular dynamics simulations of novel selective glycine transporter type 1 inhibitors with memory enhancing properties. Heliyon vol 9 issue 2 2023 36865465 |
molecular docking results indicated that the predicted inhibitors block glyt1, reacting specifically with phe319, phe325, tyr123, tyr 124, arg52, asp475, ala117, ala479, ile116 and ile483\xc2\xa0amino acids of the dopamine transporter (dat) membrane protein. |
2023-03-03 |
2023-03-06 |
human |
| Sara Af Bjerk\\xc3\\xa9n, Jan Axelsson, Anne Larsson, Carolina Flygare, Jussi Remes, Sara Strandberg, Linda Eriksson, David B\\xc3\\xa4ckstr\\xc3\\xb6m, Susanna Jakobson M. Reliability and validity of visual analysis of [18F]FE-PE2I PET/CT in early Parkinsonian disease. Nuclear medicine communications vol issue 2023 36862448 |
[18f]fe-pe2i (fe-pe2i) is a new radiotracer for dopamine transporter (dat) imaging with pet. |
2023-03-02 |
2023-03-06 |
Not clear |
| Seongbeom Park, Young Hee Sung, Woo Ram Kim, Young Noh, Eung Yeop Ki. Correlation Between Neuromelanin-Sensitive MRI and Journal of clinical neurology (Seoul, Korea) vol 19 issue 2 2023 36854333 |
correlation between neuromelanin-sensitive mri and the correlation between dopamine transporter (dat) imaging and neuromelanin-sensitive magnetic resonance imaging (nm-mri) in early-stage parkinson's disease (pd) has not yet been established. |
2023-02-28 |
2023-03-06 |
Not clear |
| Youssef Chahid, Zulfiqar H Sheikh, Max Mitropoulos, Jan Booi. A systematic review of the potential effects of medications and drugs of abuse on dopamine transporter imaging using [ European journal of nuclear medicine and molecular imaging vol issue 2023 36847827 |
a systematic review of the potential effects of medications and drugs of abuse on dopamine transporter imaging using [ in routine practice, dopamine transporter (dat) imaging is frequently used as a diagnostic tool to support the diagnosis of parkinson's disease or dementia with lewy bodies. |
2023-02-27 |
2023-03-06 |
Not clear |
| Elena Contaldi, Luca Magistrelli, Alessia Furgiuele, Silvia Gallo, Cristoforo Com. Relationship between [ Journal of neurology vol issue 2023 36840790 |
nonetheless, the exact relationship with dopamine transporter (dat) spect denervation patterns is currently unknown. |
2023-02-25 |
2023-03-06 |
Not clear |
| V S Kerstens, P Fazio, M Sundgren, J Brumberg, C Halldin, P Svenningsson, A Varron. Longitudinal DAT changes measured with [ NeuroImage. Clinical vol 37 issue 2023 36822016 |
longitudinal dat changes measured with [ dopamine transporter (dat) pet provides higher resolution than dat spect and opportunity for integrated imaging with mri. |
2023-02-23 |
2023-03-06 |
Not clear |
| Ashley L Holloway, Michael D Schaid, Talia N Lerne. Chronically dysregulated corticosterone impairs dopaminergic transmission in the dorsomedial striatum by sex-divergent mechanisms. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology vol issue 2023 36810463 |
in male but not female mice, cort treatment impaired the function of the dopamine transporter (dat) in dms. |
2023-02-22 |
2023-03-06 |
mouse |
| Maciej M Jankowski, Bogna M Ignatowska-Jankowska, Wojciech Glac, Marek Wiergowski, Paulina Kazmierska-Grebowska, Artur H Swiergie. Intravenous haloperidol and cocaine alter the distribution of T CD3 Clinical and experimental pharmacology & physiology vol issue 2023 36802086 |
cocaine non-specifically increases dopamine transmission by blocking dopamine active transporter (dat) and evokes behavioral arousal, while haloperidol is a non-specific d2-like dopamine receptor antagonist with sedative effects. |
2023-02-21 |
2023-03-06 |
rat |
| Da Hee Jung, Hong Ju Lee, Young Whan Choi, Hwa Kyoung Shin, Byung Tae Cho. Sex-specific responses to juvenile stress on the dopaminergic system in an animal model of attention-deficit hyperactivity disorder. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie vol 160 issue 2023 36738506 |
dopamine clearance factors involved in dopamine degradation and transport, especially catechol-o-methyltransferase (comt) and dopamine transporter (dat), showed sex-specific differences induced by juvenile stress in dopamine metabolite assays. |
2023-02-04 |
2023-03-06 |
rat |
| Chan Lee, Jung-Hee Jang, Gyu Hwan Par. \\xce\\xb1-Pinene Attenuates Methamphetamine-Induced Conditioned Place Preference in C57BL/6 Mice. Biomolecules & therapeutics vol issue 2023 36733209 |
methamphetamine (meth) is a powerful neurotoxic psychostimulant affecting dopamine transporter (dat) activity and leading to continuous excess extracellular dopamine levels. |
2023-02-03 |
2023-03-06 |
mouse |
| Haejun Lee, Young Hee Sung, Kyung Hoon Hwan. Additional Role of Midbrain F-18 FP-CIT Uptake on PET in Evaluation of Essential Tremor and Parkinsonism. Current medical imaging vol issue 2023 36734891 |
fluorine-18 n-(3-fluoropropyl)-2\xce\xb2carboxymethoxy-3\xce\xb2-(4-iodophenyl) nortropane (f-18 fp-cit) has been used in the evaluation of parkinsonism by its uptake in the dopamine active transporter (dat) of the striatum. |
2023-02-03 |
2023-03-06 |
Not clear |
| Marco Niello, Spyridon Sideromenos, Ralph Gradisch, Ronan O Shea, Jakob Schwazer, Julian Maier, Nina Kastner, Walter Sandtner, Kathrin J\\xc3\\xa4ntsch, Carl R Lupica, Alexander F Hoffman, Gert Lubec, Claus J Loland, Thomas Stockner, Daniela D Pollak, Michael H Baumann, Harald H Sitt. Persistent binding at dopamine transporters determines sustained psychostimulant effects. Proceedings of the National Academy of Sciences of the United States of America vol 120 issue 6 2023 36730201 |
psychostimulants interacting with the dopamine transporter (dat) can be used illicitly or for the treatment of specific neuropsychiatric disorders. |
2023-02-02 |
2023-03-06 |
mouse |
| Dieter Kunz, Sophia Stotz, Jan de Zeeuw, Alexandra Papakonstantinou, Susanne D\\xc3\\xbcmchen, Martin Haberecht, Michail Plotkin, Frederik Be. Prognostic biomarkers in prodromal \\xce\\xb1-synucleinopathies: DAT binding and REM sleep without atonia. Journal of neurology, neurosurgery, and psychiatry vol issue 2023 36725328 |
the most reliable marker of progression is reduced striatal dopamine transporter (dat) binding, but low availability of imaging facilities limits general use. |
2023-02-01 |
2023-03-06 |
Not clear |
| Adithya Gopinath, Tabish Riaz, Emily Miller, Leah Phan, Aidan Smith, Ohee Syed, Stephen Franks, Luis R Martinez, Habibeh Khoshboue. Methamphetamine induces a low dopamine transporter expressing immunophenotype without altering total number of peripheral immune cells. Basic & clinical pharmacology & toxicology vol issue 2023 36710070 |
methamphetamine is a widely abused psychostimulant and one of the main targets of dopamine transporter (dat). |
2023-01-29 |
2023-01-31 |
mouse |
| Adithya Gopinath, Phillip M Mackie, Leah T Phan, Rosa Mirabel, Aidan R Smith, Emily Miller, Stephen Franks, Ohee Syed, Tabish Riaz, Brian K Law, Nikhil Urs, Habibeh Khoshboue. Who Knew? Dopamine Transporter Activity Is Critical in Innate and Adaptive Immune Responses. Cells vol 12 issue 2 2023 36672204 |
the dopamine transporter (dat) regulates the dimension and duration of dopamine transmission. |
2023-01-21 |
2023-01-30 |
mouse |