| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bart A Ellenbroek, Eric P M Prinsse. Can 5-HT3 antagonists contribute toward the treatment of schizophrenia? Behavioural pharmacology. vol 26. issue 1-2. 2015-09-03. PMID:25356732. |
since then, considerable attention has focused on the interaction between dopamine and 5-ht and it is now well accepted that most antipsychotics (especially the second-generation drugs) modulate both dopaminergic and serotonergic receptors. |
2015-09-03 |
2023-08-13 |
human |
| Scott E Luka. New perspectives on using brain imaging to study CNS stimulants. Neuropharmacology. vol 87. 2015-08-04. PMID:25080072. |
the dopamine theory of stimulant abuse does not sufficiently explain this disorder as serotonergic, gabaergic and glutamagergic circuits are clearly involved in stimulant pharmacology and so tracking the source of the "addictive" processes must adopt a more multimodal, multidisciplinary approach. |
2015-08-04 |
2023-08-13 |
Not clear |
| Flavia Niccolini, Lorenzo Rocchi, Marios Politi. Molecular imaging of levodopa-induced dyskinesias. Cellular and molecular life sciences : CMLS. vol 72. issue 11. 2015-07-31. PMID:25681866. |
lines of evidence from pet studies indicate that serotonergic terminals could also be responsible for the development of lids in pd by aberrantly processing exogenous levodopa and by releasing dopamine in a dysregulated manner from the serotonergic terminals. |
2015-07-31 |
2023-08-13 |
Not clear |
| Julia Seibert, Cédric M Hysek, Carlos A Penno, Yasmin Schmid, Denise V Kratschmar, Matthias E Liechti, Alex Odermat. Acute effects of 3,4-methylenedioxymethamphetamine and methylphenidate on circulating steroid levels in healthy subjects. Neuroendocrinology. vol 100. issue 1. 2015-07-21. PMID:24903002. |
mdma primarily enhances serotonergic neurotransmission, and methylphenidate increases dopamine but has no serotonergic effects. |
2015-07-21 |
2023-08-13 |
human |
| Pia Baldinger, Andreas Hahn, Markus Mitterhauser, Georg S Kranz, Marion Friedl, Wolfgang Wadsak, Christoph Kraus, Johanna Ungersböck, Annette Hartmann, Ina Giegling, Dan Rujescu, Siegfried Kasper, Rupert Lanzenberge. Impact of COMT genotype on serotonin-1A receptor binding investigated with PET. Brain structure & function. vol 219. issue 6. 2015-07-07. PMID:23928748. |
given the close interactions between serotonergic and dopaminergic neurotransmission, we investigated whether a common single-nucleotide-polymorphism of the catechol-o-methyltransferase (comt) gene (val158met or rs4680) coding for a key enzyme of the dopamine network that is associated with the pathogenesis of mood disorders and antidepressant treatment response, directly affects 5-ht1a receptor binding potential. |
2015-07-07 |
2023-08-12 |
human |
| Per Svenningsson, Carl Rosenblad, Karolina Af Edholm Arvidsson, Klas Wictorin, Charlotte Keywood, Bavani Shankar, David A Lowe, Anders Björklund, Håkan Widne. Eltoprazine counteracts l-DOPA-induced dyskinesias in Parkinson's disease: a dose-finding study. Brain : a journal of neurology. vol 138. issue Pt 4. 2015-06-16. PMID:25669730. |
in advanced stages of parkinson's disease, serotonergic terminals take up l-dopa and convert it to dopamine. |
2015-06-16 |
2023-08-13 |
Not clear |
| R Nageswara Rao, K Guru Prasa. Stereo-specific LC and LC-MS bioassays of antidepressants and psychotics. Biomedical chromatography : BMC. vol 29. issue 1. 2015-06-04. PMID:25355601. |
selective serotonin reuptake inhibitors, serotonin and norepinephrine reuptake inhibitors, noradrenergic and specific serotonergic antidepressants, norepinephrine reuptake inhibitors, norepinephrine-dopamine reuptake inhibitors, nonamphetamine central nervous system stimulants, serotonin and dopamine inhibitors and γ-aminobutyric acid receptor agonists in biological matrices. |
2015-06-04 |
2023-08-13 |
Not clear |
| Elisabeth Y Bijlsma, Johnny S W Chan, Berend Olivier, Jan G Veening, Mark J Millan, Marcel D Waldinger, Ronald S Oostin. Sexual side effects of serotonergic antidepressants: mediated by inhibition of serotonin on central dopamine release? Pharmacology, biochemistry, and behavior. vol 121. 2015-05-11. PMID:24128918. |
sexual side effects of serotonergic antidepressants: mediated by inhibition of serotonin on central dopamine release? |
2015-05-11 |
2023-08-12 |
rat |
| Enrica Olivola, Mariangela Pierantozzi, Paola Imbriani, Claudio Liguori, Mario Stampanoni Bassi, Marco Conti, Vincenza D'Angelo, Nicola Biagio Mercuri, Alessandro Stefan. Serotonin impairment in CSF of PD patients, without an apparent clinical counterpart. PloS one. vol 9. issue 7. 2015-03-30. PMID:25036938. |
lp was performed following three days of therapy withdrawal, in order to vanish the effects of prolonged released dopamine agonists (da), and in absence of any serotonergic agent. |
2015-03-30 |
2023-08-13 |
human |
| Eun-Jung Park, Young-Gi Min, Gi-woon Kim, Joon-pil Cho, Woo-jae Maeng, Sang-cheon Cho. Pathophysiology of brain injuries in acute carbon monoxide poisoning: a novel hypothesis. Medical hypotheses. vol 83. issue 2. 2015-02-09. PMID:24857260. |
a dopamine excess could lead to oxidative metabolism of dopamine, serotonergic axonal injury, or secondary myelin damage. |
2015-02-09 |
2023-08-13 |
Not clear |
| Claudia Rangel-Barajas, Maninder Malik, Suwanna Vangveravong, Robert H Mach, Robert R Luedtk. Pharmacological modulation of abnormal involuntary DOI-induced head twitch response in male DBA/2J mice: I. Effects of D2/D3 and D2 dopamine receptor selective compounds. Neuropharmacology. vol 83. 2015-01-29. PMID:24680675. |
this observation suggests a functional interaction between dopaminergic and serotonergic systems through d2 dopamine receptors and the 5-ht2a serotonin receptors in vivo. |
2015-01-29 |
2023-08-12 |
mouse |
| J David Jentsch, James R Ashenhurst, M Catalina Cervantes, Stephanie M Groman, Alexander S James, Zachary T Penningto. Dissecting impulsivity and its relationships to drug addictions. Annals of the New York Academy of Sciences. vol 1327. 2014-12-23. PMID:24654857. |
while the evidence indicating that subtypes of impulsive behavior are uniquely informative--either biologically or with respect to their relationships to addictions--is convincing, multiple lines of study link distinct subtypes of impulsivity to low dopamine d2 receptor function and perturbed serotonergic transmission, revealing shared mechanisms between the subtypes. |
2014-12-23 |
2023-08-12 |
Not clear |
| Michelle G Baladi, Amy H Newman, Shannon M Nielsen, Glen R Hanson, Annette E Fleckenstei. Dopamine D(3) receptors contribute to methamphetamine-induced alterations in dopaminergic neuronal function: role of hyperthermia. European journal of pharmacology. vol 732. 2014-12-09. PMID:24685638. |
the present study extended these findings by testing the role of the dopamine d3 receptor subtype in mediating the long-term dopaminergic, and for comparison serotonergic, deficits caused by methamphetamine. |
2014-12-09 |
2023-08-12 |
rat |
| Susana Marques de Sousa, João Massan. Motor complications in Parkinson's disease: a comprehensive review of emergent management strategies. CNS & neurological disorders drug targets. vol 12. issue 7. 2014-11-12. PMID:23844692. |
glutamatergic, serotonergic, noradrenergic, adenosinergic and cholinergic systems), gene therapy for delivering neurotrophic factors or critical enzymes for dopamine synthesis, and cell therapy. |
2014-11-12 |
2023-08-12 |
Not clear |
| Carlos D Silva, Ana F Neves, Ana I Dias, Hugo J Freitas, Sheena M Mendes, Inês Pita, Sofia D Viana, Paulo A de Oliveira, Rodrigo A Cunha, Carlos A Fontes Ribeiro, Rui D Prediger, Frederico C Pereir. A single neurotoxic dose of methamphetamine induces a long-lasting depressive-like behaviour in mice. Neurotoxicity research. vol 25. issue 3. 2014-11-05. PMID:24072398. |
this depressive-like profile induced by meth was accompanied by a marked depletion of frontostriatal dopaminergic and serotonergic neurotransmission, indicated by a reduction in the levels of dopamine, dopac and hva, tyrosine hydroxylase and serotonin, observed at both 3 and 49 days post-administration. |
2014-11-05 |
2023-08-12 |
mouse |
| Mohammad Seyedabadi, Gohar Fakhfouri, Vahid Ramezani, Shahram Ejtemaei Mehr, Reza Rahimia. The role of serotonin in memory: interactions with neurotransmitters and downstream signaling. Experimental brain research. vol 232. issue 3. 2014-10-14. PMID:24430027. |
a large body of evidence indicates the interplay between serotonergic transmission and other neurotransmitters including acetylcholine, dopamine, γ-aminobutyric acid (gaba) and glutamate, in the neurobiological control of learning and memory. |
2014-10-14 |
2023-08-12 |
Not clear |
| N Nevalainen, S Af Bjerkén, G A Gerhardt, I Strömber. Serotonergic nerve fibers in L-DOPA-derived dopamine release and dyskinesia. Neuroscience. vol 260. 2014-09-25. PMID:24361918. |
serotonergic nerve fibers in l-dopa-derived dopamine release and dyskinesia. |
2014-09-25 |
2023-08-12 |
rat |
| F Bartelke, R Pfister, W Kämmere. [Perioperative approach to restless legs syndrome]. Der Anaesthesist. vol 62. issue 12. 2014-08-11. PMID:24292123. |
drugs with dopamine antagonistic, serotonergic and opioid antagonistic effects should be avoided. |
2014-08-11 |
2023-08-12 |
Not clear |
| O Sader-Mazbar, Y Loboda, M J Rabey, J P M Finber. Increased L-DOPA-derived dopamine following selective MAO-A or -B inhibition in rat striatum depleted of dopaminergic and serotonergic innervation. British journal of pharmacology. vol 170. issue 5. 2014-08-08. PMID:23992249. |
increased l-dopa-derived dopamine following selective mao-a or -b inhibition in rat striatum depleted of dopaminergic and serotonergic innervation. |
2014-08-08 |
2023-08-12 |
rat |
| Robin M Murray, Alessandra Paparelli, Paul D Morrison, Arianna Marconi, Marta Di Fort. What can we learn about schizophrenia from studying the human model, drug-induced psychosis? American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 162B. issue 7. 2014-05-27. PMID:24132898. |
research into the effects of lsd initiated the serotonergic model; amphetamines the dopamine hypothesis, pcp and ketamine the glutamatergic hypothesis, while most recently the effects of cannabis have provoked interest in the role of endocannabinoids in schizophrenia. |
2014-05-27 |
2023-08-12 |
human |