| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Roberto Mandrioli, Michele Protti, Laura Mercolin. New-Generation, Non-SSRI Antidepressants: Therapeutic Drug Monitoring and Pharmacological Interactions. Part 1: SNRIs, SMSs, SARIs. Current medicinal chemistry. vol 25. issue 7. 2018-04-03. PMID:28707591. |
after the introduction of selective serotonin reuptake inhibitors (ssris), a plethora of other groups followed, identified by their main mechanisms of activity: serotonin and norepinephrine reuptake inhibitors (snri); serotonin modulators and stimulators (sms); serotonin antagonists and reuptake inhibitors (sari); noradrenergic and selective serotonergic antidepressants (nassa); norepinephrine reuptake inhibitors (neri); serotonin, norepinephrine and dopamine reuptake inhibitors (sndri) or triple reuptake inhibitors (tri); and melatonin and serotonin agonists (masa). |
2018-04-03 |
2023-08-13 |
Not clear |
| Cristina Miguelez, Sylvia Navailles, Claire Delaville, Loïse Marquis, Mélanie Lagière, Abdelhamid Benazzouz, Luisa Ugedo, Philippe De Deurwaerdèr. L-DOPA elicits non-vesicular releases of serotonin and dopamine in hemiparkinsonian rats in vivo. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 26. issue 8. 2018-01-23. PMID:27234917. |
this strategy deserves further investigation because it is presently unclear whether l-dopa promotes a non-vesicular release of dopamine and serotonin from serotonergic neurons. |
2018-01-23 |
2023-08-13 |
rat |
| Martijn Figee, Tommy Pattij, Ingo Willuhn, Judy Luigjes, Wim van den Brink, Anneke Goudriaan, Marc N Potenza, Trevor W Robbins, Damiaan Deny. Compulsivity in obsessive-compulsive disorder and addictions. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 26. issue 5. 2018-01-19. PMID:26774279. |
the reviewed data suggest that compulsivity in ocd and addictions is related to impaired reward and punishment processing with attenuated dopamine release in the ventral striatum, negative reinforcement in limbic systems, cognitive and behavioral inflexibility with diminished serotonergic prefrontal control, and habitual responding with imbalances between ventral and dorsal frontostriatal recruitment. |
2018-01-19 |
2023-08-13 |
Not clear |
| Sinead E Shortall, Clare H Spicer, Francis J P Ebling, A Richard Green, Kevin C F Fone, Madeleine V Kin. Contribution of serotonin and dopamine to changes in core body temperature and locomotor activity in rats following repeated administration of mephedrone. Addiction biology. vol 21. issue 6. 2018-01-16. PMID:26180025. |
this study examined the effects of repeated mephedrone administration on locomotor activity, body temperature and striatal dopamine and 5-hydroxytryptamine (5-ht) levels and the role of dopaminergic and serotonergic neurons in these responses. |
2018-01-16 |
2023-08-13 |
rat |
| Panayotis K Thanos, Lauren Malave, Foteini Delis, Paul Mangine, Katie Kane, Adam Grunseich, Melissa Vitale, Paul Greengard, Nora D Volko. Knockout of p11 attenuates the acquisition and reinstatement of cocaine conditioned place preference in male but not in female mice. Synapse (New York, N.Y.). vol 70. issue 7. 2017-12-22. PMID:26990537. |
cocaine's enhancement of dopamine signaling is crucial for its rewarding effects but its serotonergic effects are also relevant. |
2017-12-22 |
2023-08-13 |
mouse |
| A P N de Lima, T M Sandini, T M Reis-Silva, C O Massoc. Long-lasting monoaminergic and behavioral dysfunctions in a mice model of socio-environmental stress during adolescence. Behavioural brain research. vol 317. 2017-12-05. PMID:27641324. |
furthermore, decreased serotonergic activity on hippocampus, hypothalamus and cortex, decreased noradrenergic activity on hippocampus and hypothalamus, and increased the turnover of dopamine in cortex. |
2017-12-05 |
2023-08-13 |
mouse |
| Christopher Norris, Michael Loureiro, Cecilia Kramar, Jordan Zunder, Justine Renard, Walter Rushlow, Steven R Laviolett. Cannabidiol Modulates Fear Memory Formation Through Interactions with Serotonergic Transmission in the Mesolimbic System. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 12. 2017-09-11. PMID:27296152. |
cbd has been reported to functionally interact with both the mesolimbic dopamine (da) and serotonergic (5-ht) receptor systems. |
2017-09-11 |
2023-08-13 |
rat |
| Masakatsu Kanazawa, Hiroyuki Ohba, Shingo Nishiyama, Takeharu Kakiuchi, Hideo Tsukad. Effect of MPTP on Serotonergic Neuronal Systems and Mitochondrial Complex I Activity in the Living Brain: A PET Study on Conscious Rhesus Monkeys. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 58. issue 7. 2017-08-18. PMID:28280215. |
the objective of the present pet study was to compare the effect of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) on serotonergic neuronal systems and mitochondrial complex i (mc-i) activity with that of dopamine in conscious rhesus monkeys ( |
2017-08-18 |
2023-08-13 |
monkey |
| M Soyk. Relapse Prevention in Alcoholism : Recent Advances and Future Possibilities. CNS drugs. vol 7. issue 4. 2016-08-17. PMID:27520754. |
the glutamatergic, opioid-endorphin, mesolimbic dopamine, and serotonergic systems are believed to be of special relevance to the positive reinforcing effects of alcohol and clinical phenomena such as craving. |
2016-08-17 |
2023-08-13 |
Not clear |
| Linn E Katus, Steven J Fruch. Management of Serotonin Syndrome and Neuroleptic Malignant Syndrome. Current treatment options in neurology. vol 18. issue 9. 2016-07-29. PMID:27469512. |
agents to reverse either surplus serotonergic activity or dopamine blockage can be useful. |
2016-07-29 |
2023-08-13 |
Not clear |
| Hamed Shafaroodi, Simin Oveisi, Mahsa Hosseini, Hossein Niknahad, Leila Moez. The effect of acute aripiprazole treatment on chemically and electrically induced seizures in mice: The role of nitric oxide. Epilepsy & behavior : E&B. vol 48. 2016-05-05. PMID:26037847. |
dopaminergic and serotonergic systems relate to nitric oxide, and aripiprazole also has effects on dopamine and serotonin receptors. |
2016-05-05 |
2023-08-13 |
mouse |
| Krisna Patel, Sophie Allen, Mariam N Haque, Ilinca Angelescu, David Baumeister, Derek K Trac. Bupropion: a systematic review and meta-analysis of effectiveness as an antidepressant. Therapeutic advances in psychopharmacology. vol 6. issue 2. 2016-05-04. PMID:27141292. |
it has a unique pharmacology, inhibiting the reuptake of noradrenaline and dopamine, potentially providing pharmacological augmentation to more common antidepressants such as selective serotonergic reuptake inhibitors (ssris). |
2016-05-04 |
2023-08-13 |
Not clear |
| Perdita Cheshire, Scott Ayton, Kelly L Bertram, Helen Ling, Abi Li, Catriona McLean, Glenda M Halliday, Sean S O'Sullivan, Tamas Revesz, David I Finkelstein, Elsdon Storey, David R William. Serotonergic markers in Parkinson's disease and levodopa-induced dyskinesias. Movement disorders : official journal of the Movement Disorder Society. vol 30. issue 6. 2016-04-07. PMID:25649148. |
we obtained brain tissue from 44 pd cases and 17 age-matched controls and assessed monoamine levels and the serotonin and dopamine transporters in the striatum, and the extent of dopaminergic and serotonergic cell preservation in the substantia nigra (sn) and the dorsal raphe nuclei (drn), respectively. |
2016-04-07 |
2023-08-13 |
Not clear |
| Gurdal Sahin, Lachlan H Thompson, Sonia Lavisse, Merve Ozgur, Latifa Rbah-Vidal, Frédéric Dollé, Philippe Hantraye, Deniz Kiri. Differential dopamine receptor occupancy underlies L-DOPA-induced dyskinesia in a rat model of Parkinson's disease. PloS one. vol 9. issue 3. 2016-03-31. PMID:24614598. |
the prevailing view for the underlying presynaptic mechanism of l-dopa-induced dyskinesia (lid) suggests that surges in dopamine (da) via uncontrolled release from serotonergic terminals results in abnormally high level of extracellular striatal dopamine. |
2016-03-31 |
2023-08-12 |
rat |
| Pei Jiang, Li-Hong Zhang, Hua-Lin Cai, Huan-De Li, Yi-Ping Liu, Mi-Mi Tang, Rui-Li Dang, Wen-Ye Zhu, Ying Xue, Xin H. Neurochemical effects of chronic administration of calcitriol in rats. Nutrients. vol 6. issue 12. 2015-11-25. PMID:25533012. |
however, the concentrations of the metabolites of dopamine and serotonin were increased and the drug use also resulted in a significant rise of monoamine oxidase a (maoa) expression, which might be responsible to maintain the homeostasis of dopaminergic and serotonergic neurotransmission. |
2015-11-25 |
2023-08-13 |
rat |
| Marta Krzyżanowska, Johann Steiner, Ralf Brisch, Christian Mawrin, Stefan Busse, Katharina Braun, Zbigniew Jankowski, Hans-Gert Bernstein, Bernhard Bogerts, Tomasz Go. Ribosomal DNA transcription in the dorsal raphe nucleus is increased in residual but not in paranoid schizophrenia. European archives of psychiatry and clinical neuroscience. vol 265. issue 2. 2015-11-12. PMID:25091423. |
the central serotonergic system is implicated in the pathogenesis of schizophrenia, where the imbalance between dopamine, serotonin and glutamate plays a key pathophysiological role. |
2015-11-12 |
2023-08-13 |
Not clear |
| Matthew O Parker, Alistair J Brock, Ari Sudwarts, Muy-Teck Teh, Fraser J Combe, Caroline H Brenna. Developmental role of acetylcholinesterase in impulse control in zebrafish. Frontiers in behavioral neuroscience. vol 9. 2015-11-03. PMID:26528153. |
assessment of expression of cholinergic (nachr), serotonergic (5-ht), and dopamine (dr) receptor mrna in both adult and larval (9 dpf) ache (sb55/+) revealed significant downregulation of chrna2, chrna5, and drd2 mrna in ache (sb55/+) larvae, but no differences in adults. |
2015-11-03 |
2023-08-13 |
zebrafish |
| Bianca C Wittmann, Mark D'Esposit. Levodopa administration modulates striatal processing of punishment-associated items in healthy participants. Psychopharmacology. vol 232. issue 1. 2015-10-16. PMID:24923987. |
on a neural level, reward and its predictors are associated with increased firing of dopaminergic neurons, whereas punishment processing has been linked to the serotonergic system and to decreases in dopamine transmission. |
2015-10-16 |
2023-08-13 |
human |
| Matthias Liecht. Novel psychoactive substances (designer drugs): overview and pharmacology of modulators of monoamine signaling. Swiss medical weekly. vol 145. 2015-09-25. PMID:25588018. |
typically, stimulants inhibit the transport of dopamine and noradrenaline (pipradrols, pyrovalerone cathinones) or induce the release of these monoamines (amphetamines and methamphetamine-like cathinones), entactogens predominantly enhance serotonin release (phenylpiperazines, aminoindanes, para-substituted amphetamines, and mdma-like cathinones) similar to mdma (ecstasy), and hallucinogens (tryptamines, hallucinogenic phenethylamines) are direct agonists at serotonergic 5-ht2a receptors. |
2015-09-25 |
2023-08-13 |
Not clear |
| Ryosei Goda, Tsuyoshi Otsuka, Ayaka Iwamoto, Misato Kawai, Satomi Shibata, Mitsuhiro Furuse, Shinobu Yasu. Serotonin levels in the dorsal raphe nuclei of both chipmunks and mice are enhanced by long photoperiod, but brain dopamine level response to photoperiod is species-specific. Neuroscience letters. vol 593. 2015-09-08. PMID:25797183. |
in conclusion, photoperiod may regulate the brain serotonergic system through similar mechanisms, regardless of whether the animals are diurnal or nocturnal, but photoperiod-dependent regulation of brain dopamine is species-specific. |
2015-09-08 |
2023-08-13 |
mouse |