| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Piotr Wierzbiński, Joanna Hubska, Michał Henzler, Bartłomiej Kucharski, Rafał Bieś, Marek Krzystane. Depressive and Other Adverse CNS Effects of Fluoroquinolones. Pharmaceuticals (Basel, Switzerland). vol 16. issue 8. 2023-08-26. PMID:37631020. |
it is believed that the antagonistic effect of fqs on the gaba receptor or interaction with the main receptor for the glutamatergic system-nmda-is responsible for this. |
2023-08-26 |
2023-09-07 |
Not clear |
| Rosana Carvalho Silva, Claudia Pisanu, Elisabetta Maffioletti, Valentina Menesello, Marco Bortolomasi, Massimo Gennarelli, Bernhard T Baune, Alessio Squassina, Alessandra Minell. Biological markers of sex-based differences in major depressive disorder and in antidepressant response. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 76. 2023-08-18. PMID:37595325. |
the majority of the reviewed studies were performed through candidate gene approaches, focusing on biological systems involved in mdd pathophysiology, including the stress response, inflammatory and immune, monoaminergic, neurotrophic, gamma-aminobutyric acid and glutamatergic, and oxytocin systems. |
2023-08-18 |
2023-10-07 |
human |
| Bernhard Luscher, Jamie L Maguire, Uwe Rudolph, Etienne Sibill. GABA Trends in pharmacological sciences. 2023-08-05. PMID:37543478. |
gaba in the past 20 years, our understanding of the pathophysiology of depression has evolved from a focus on an imbalance of monoaminergic neurotransmitters to a multifactorial picture including an improved understanding of the role of glutamatergic excitatory and gabaergic inhibitory neurotransmission. |
2023-08-05 |
2023-08-14 |
Not clear |
| Anne S Mallien, Christiane Brandwein, Andrei-Nicolae Vasilescu, Cathalijn Leenaars, André Bleich, Dragos Inta, Dusan Hirjak, Peter Gas. A systematic scoping review of rodent models of catatonia: Clinical correlations, translation and future approaches. Schizophrenia research. 2023-07-31. PMID:37524635. |
the majority of behavioral and neuroimaging studies in psychiatric patients suggested aberrant higher-order frontoparietal networks which, on the biochemical level, are insufficiently modulated by gamma-aminobutyric acid (gaba)-ergic and glutamatergic transmission. |
2023-07-31 |
2023-08-14 |
Not clear |
| Yunjiang Yu, Shihui Tan, Dongli Xie, Hongyan Li, Haibo Chen, Yao Dang, Mingdeng Xian. Photoaged microplastics induce neurotoxicity associated with damage to serotonergic, glutamatergic, dopaminergic, and GABAergic neuronal systems in Caenorhabditis elegans. The Science of the total environment. 2023-07-30. PMID:37517734. |
exposure to p-ps also altered the fluorescence intensity and neurodegeneration percentage of serotonergic, glutamatergic, dopaminergic, and aminobutyric acid (gaba) in transgenic nematodes. |
2023-07-30 |
2023-08-14 |
caenorhabditis_elegans |
| Daniela Neuhofer, Peter Kaliva. Differential modulation of GABAergic and glutamatergic neurons in the ventral pallidum by GABA and neuropeptides. eNeuro. 2023-07-06. PMID:37414552. |
differential modulation of gabaergic and glutamatergic neurons in the ventral pallidum by gaba and neuropeptides. |
2023-07-06 |
2023-08-14 |
mouse |
| Daniela Neuhofer, Peter Kaliva. Differential modulation of GABAergic and glutamatergic neurons in the ventral pallidum by GABA and neuropeptides. eNeuro. 2023-07-06. PMID:37414552. |
nk1r activation inhibited glutamatergic transmission only on vglut(+) cells.our results indicate that the afferent-specific release of gaba and neuropeptides from d1- and d2-msns can differentially influence vp neuronal subtypes. |
2023-07-06 |
2023-08-14 |
mouse |
| Ji Won Bang, Carlos Parra, Kevin Yu, Gadi Wollstein, Joel S Schuman, Kevin C Cha. GABA decrease is associated with degraded neural specificity in the visual cortex of glaucoma patients. Communications biology. vol 6. issue 1. 2023-06-29. PMID:37386293. |
here, using proton magnetic resonance spectroscopy and functional magnetic resonance imaging, we investigated the gabaergic and glutamatergic systems in the visual cortex of glaucoma patients, as well as neural specificity, which is shaped by gaba and glutamate signals and underlies efficient sensory and cognitive functions. |
2023-06-29 |
2023-08-14 |
Not clear |
| Ali Azargoonjahrom. A systematic review of the association between zinc and anxiety. Nutrition reviews. 2023-06-26. PMID:37364014. |
zinc, which is an essential nutrient found in various plants, animal foods, and supplements, has been shown to be a potential nutrient in anxiety reduction by acting on γ-aminobutyric acid (gaba), glutamatergic, serotonergic, neurogenesis, and immune systems. |
2023-06-26 |
2023-08-14 |
Not clear |
| Timo Ueberbach, Clara A Simacek, Irmgard Tegeder, Sergei Kirischuk, Thomas Mittman. Tonic activation of GABA Frontiers in synaptic neuroscience. vol 15. 2023-06-16. PMID:37325697. |
tonic activation of gaba the efficiency of neocortical information processing critically depends on the balance between the glutamatergic (excitatory, e) and gabaergic (inhibitory, i) synaptic transmission. |
2023-06-16 |
2023-08-14 |
mouse |
| Oliver Kan. Lactate as a supplemental fuel for synaptic transmission and neuronal network oscillations: Potentials and limitations. Journal of neurochemistry. 2023-06-13. PMID:37309602. |
moreover, lactate attenuates neurotransmission in glutamatergic pyramidal cells and fast-spiking, γ-aminobutyric acid (gaba)ergic interneurons by reducing neurotransmitter release from presynaptic terminals. |
2023-06-13 |
2023-08-14 |
Not clear |
| Hannah M Oberle, Alexander N Ford, Jordyn E Czarny, Meike M Rogalla, Pierre F Apostolide. Recurrent circuits amplify corticofugal signals and drive feedforward inhibition in the inferior colliculus. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-06-12. PMID:37308295. |
perplexingly, anatomy studies imply that corticofugal axons primarily target glutamatergic ic neurons while only sparsely innervating ic gaba neurons. |
2023-06-12 |
2023-08-14 |
Not clear |
| Jo Sourbron, Lieven Laga. Fenfluramine: a plethora of mechanisms? Frontiers in pharmacology. vol 14. 2023-05-30. PMID:37251322. |
our review highlights the importance of serotonin and sigma-1 receptor mechanisms in maintaining a balance between excitatory (glutamatergic) and inhibitory (γ-aminobutyric acid [gaba]-ergic) neural networks, and suggests that these mechanisms may represent primary pharmacological moas in seizures, non-seizure comorbidities, and sudep. |
2023-05-30 |
2023-08-14 |
Not clear |
| Shaohua Ma, Hao Zhong, Xuemei Liu, Liping Wan. Spatial Distribution of Neurons Expressing Single, Double, and Triple Molecular Characteristics of Glutamatergic, Dopaminergic, or GABAergic Neurons in the Mouse Ventral Tegmental Area. Journal of molecular neuroscience : MN. 2023-05-27. PMID:37243808. |
the vta contains three main neuronal populations, namely, dopamine (da), γ-aminobutyric acid (gaba), and glutamate neurons, but some neurons exhibit combinatorial molecular characteristics of dopaminergic, gabaergic, or glutamatergic neurons. |
2023-05-27 |
2023-08-14 |
mouse |
| Josua Zimmermann, Niklaus Zölch, Rebecca Coray, Francesco Bavato, Nicole Friedli, Markus R Baumgartner, Andrea E Steuer, Antje Opitz, Annett Werner, Georg Oeltzschner, Erich Seifritz, Ann Kathrin Stock, Christian Beste, David M Cole, Boris B Quedno. Chronic 3,4-Methylenedioxymethamphetamine (MDMA) use is related to glutamate and GABA concentrations in the striatum, but not in the anterior cingulate cortex. The international journal of neuropsychopharmacology. 2023-05-26. PMID:37235749. |
however, serotonin functions are strongly entangled with glutamate as well as γ-aminobutyric acid (gaba) neurotransmission and studies in mdma-exposed rats show long-term adaptations in glutamatergic and gabaergic signaling. |
2023-05-26 |
2023-08-14 |
rat |
| Songul Ozkula, Mahluga Jafarova Demirkapu, Hasan Raci Yananli, Banu Aydin, Cevdet Nacar, Hulya Cabada. The effect of acute topiramate administration on morphine withdrawal syndrome and brain-derived neurotrophic factor in central nervous system. Neurological research. 2023-04-27. PMID:37105528. |
topiramate, increases postsynaptic gamma-aminobutyric acid receptor activity and antagonizes glutamatergic activity. |
2023-04-27 |
2023-08-14 |
Not clear |
| Andrea de Bartolomeis, Giuseppe De Simone, Michele De Prisco, Annarita Barone, Raffaele Napoli, Francesco Beguinot, Martina Billeci, Michele Fornar. Insulin effects on core neurotransmitter pathways involved in schizophrenia neurobiology: a meta-analysis of preclinical studies. Implications for the treatment. Molecular psychiatry. 2023-04-21. PMID:37085712. |
the present meta-analysis aims to assess the impact of insulin action manipulations (i.e., hyperinsulinemia, hypoinsulinemia, systemic or brain insulin resistance) on glutamatergic, dopaminergic, γ-aminobutyric acid (gaba)ergic, and serotonergic pathways in the central nervous system. |
2023-04-21 |
2023-08-14 |
Not clear |
| Rosiel Elwyn, Jules Mitchell, Michael R Kohn, Christina Driver, Phillipa Hay, Jim Lagopoulos, Daniel F Hermen. Novel Ketamine and Zinc Treatment for Anorexia Nervosa and the Potential Beneficial Interactions With the Gut Microbiome. Neuroscience and biobehavioral reviews. 2023-03-12. PMID:36907256. |
this paper outlines a neurobiological model of glutamatergic and γ-aminobutyric acid (gaba)-ergic dysfunction, exacerbated by chronic gut microbiome dysbiosis and zinc depletion at a brain and gut level. |
2023-03-12 |
2023-08-14 |
Not clear |
| Sudeepta K Basu, Subechhya Pradhan, Yushuf M Sharker, Kushal J Kapse, Jonathan Murnick, Taeun Chang, Catherine A Lopez, Nickie Andescavage, Adre J duPlessis, Catherine Limperopoulo. Severity of prematurity and age impact early postnatal development of GABA and glutamate systems. Cerebral cortex (New York, N.Y. : 1991). 2023-02-27. PMID:36843135. |
gamma-aminobutyric acid (gaba) and glutamatergic system perturbations following premature birth may explain neurodevelopmental deficits in the absence of structural brain injury. |
2023-02-27 |
2023-08-14 |
Not clear |
| Lourdes A Vega Rasgado, Eva Ramón-Gallegos, Lorena Rodríguez-Páez, Verónica Alcántara-Farfá. The opposite effect of convulsant drugs on neuronal and endothelial nitric oxide synthase - A possible explanation for the dual proconvulsive/anticonvulsive action of nitric oxide. Acta pharmaceutica (Zagreb, Croatia). vol 73. issue 1. 2023-01-24. PMID:36692466. |
apparently, nno possesses convulsant properties mediated by its effect on the glutamatergic and gabaergic systems, probably through gaba |
2023-01-24 |
2023-08-14 |
Not clear |