| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ning Sheng, Hao Zheng, Min Li, Menglin Li, Zhe Wang, Ying Peng, Haibo Yu, Jinlan Zhan. 4,5 caffeoylquinic acid and scutellarin, identified by integrated metabolomics and proteomics approach as the active ingredients of Dengzhan Shengmai, act against chronic cerebral hypoperfusion by regulating glutamatergic and GABAergic synapses. Pharmacological research. vol 152. 2021-01-04. PMID:31926275. |
the results of glutamate-induced neuronal excitatory injury cell model experiment for verification of active ingredients and mechanism of dzsm showed that there are five active ingredients, and among them, 4,5 caffeoylquinic acid (4,5-cqa) and scutellarin (sg) could simultaneously affect the gabaergic and glutamatergic synaptic metabolism as well as the related receptors, the nr2b subunit of nmda and the α1 subunit of gaba |
2021-01-04 |
2023-08-13 |
rat |
| Benjamin Spurny, Rene Seiger, Philipp Moser, Thomas Vanicek, Murray B Reed, Eva Heckova, Paul Michenthaler, Alim Basaran, Gregor Gryglewski, Manfred Klöbl, Siegfried Trattnig, Siegfried Kasper, Wolfgang Bogner, Rupert Lanzenberge. Hippocampal GABA levels correlate with retrieval performance in an associative learning paradigm. NeuroImage. vol 204. 2020-11-27. PMID:31606475. |
next to the glutamatergic system which contributes to memory formation via long-term potentiation (ltp) and long-term depression (ltd), the main inhibitory neurotransmitter, gaba is crucially involved in neuroplastic processes. |
2020-11-27 |
2023-08-13 |
human |
| Pampa Saha, Rajaneesh Gupta, Tanusree Sen, Nilkantha Se. Histone Deacetylase 4 Downregulation Elicits Post-Traumatic Psychiatric Disorders through Impairment of Neurogenesis. Journal of neurotrauma. vol 36. issue 23. 2020-11-09. PMID:31169064. |
here we have shown that an imbalance in the generation of γ-aminobutyric acid (gaba)ergic and glutamatergic neurons due to aberrant induction of vesicular glutamate transporter 1 (vglut1)-positive glutamatergic cells is responsible for impaired neuronal differentiation in the hippocampus following tbi. |
2020-11-09 |
2023-08-13 |
Not clear |
| Mei Liu, Lijuan Jiang, Min Wen, Yue Ke, Xiangzhen Tong, Weiyuan Huang, Rongqing Che. Microglia depletion exacerbates acute seizures and hippocampal neuronal degeneration in mouse models of epilepsy. American journal of physiology. Cell physiology. vol 319. issue 3. 2020-10-23. PMID:32783655. |
while the glutamatergic and gabaergic neurons play major roles in shaping fast neuronal excitation/inhibition homeostasis, it is well illustrated that astrocytes profoundly regulate neuronal excitation by controlling glutamate, gaba, cannabinoids, adenosine, and concentration of k |
2020-10-23 |
2023-08-13 |
mouse |
| Alfonso Oyarzabal, Clara Xiol, Alba Aina Castells, Cristina Grau, Mar O'Callaghan, Guerau Fernández, Soledad Alcántara, Mercè Pineda, Judith Armstrong, Xavier Altafaj, Angels García-Cazorl. Comprehensive Analysis of GABA International journal of molecular sciences. vol 21. issue 2. 2020-10-06. PMID:31947619. |
comprehensive analysis of gaba rett syndrome, a serious neurodevelopmental disorder, has been associated with an altered expression of different synaptic-related proteins and aberrant glutamatergic and γ-aminobutyric acid (gaba)ergic neurotransmission. |
2020-10-06 |
2023-08-13 |
mouse |
| Amandine Fernandez, Camille Dumon, Damien Guimond, Roman Tyzio, Paolo Bonifazi, Natalia Lozovaya, Nail Burnashev, Diana C Ferrari, Yehezkel Ben-Ar. The GABA Developmental Shift Is Abolished by Maternal Immune Activation Already at Birth. Cerebral cortex (New York, N.Y. : 1991). vol 29. issue 9. 2020-10-05. PMID:30395185. |
these alterations produced by mia persist, since at p14-15 gaba action remains depolarizing, produces excitatory action, and network activity remains elevated with a higher frequency of spontaneous glutamatergic postsynaptic currents. |
2020-10-05 |
2023-08-13 |
mouse |
| Ahmet Bulent Yazici, Esra Yazici, Atila Ero. Delirium and High Creatine Kinase and Myoglobin Levels Related to Synthetic Cannabinoid Withdrawal. Case reports in medicine. vol 2017. 2020-10-01. PMID:28487743. |
several studies reported that agonists of cb1 receptors play a role in gaba and glutamatergic neurotransmission, which is similar to the effects of alcohol on gaba and glutamatergic receptors. |
2020-10-01 |
2023-08-13 |
Not clear |
| Alan L Pehrson, Christian S Pedersen, Kirstine Sloth Tølbøl, Connie Sanche. Vortioxetine Treatment Reverses Subchronic PCP Treatment-Induced Cognitive Impairments: A Potential Role for Serotonin Receptor-Mediated Regulation of GABA Neurotransmission. Frontiers in pharmacology. vol 9. 2020-10-01. PMID:29559911. |
one theory suggests that vortioxetine improves cognition by suppressing γ-amino butyric acid (gaba)ergic neurotransmission, thereby increasing glutamatergic activation. |
2020-10-01 |
2023-08-13 |
Not clear |
| Joel E Shillinglaw, Richard A Morrisett, Regina A Mangier. Ethanol Modulates Glutamatergic Transmission and NMDAR-Mediated Synaptic Plasticity in the Agranular Insular Cortex. Frontiers in pharmacology. vol 9. 2020-10-01. PMID:30618752. |
despite evidence of aic involvement in aud, there has not yet been an examination of whether ethanol modulates glutamatergic and γ-amino-butyric acid (gaba)ergic synaptic transmission and plasticity in the aic. |
2020-10-01 |
2023-08-13 |
mouse |
| Marcos Ucha, David Roura-Martínez, Ana Contreras, Sheyla Pinto-Rivero, Javier Orihuel, Emilio Ambrosio, Alejandro Higuera-Mata. Impulsive Action and Impulsive Choice Are Differentially Associated With Gene Expression Variations of the GABA Frontiers in behavioral neuroscience. vol 13. 2020-10-01. PMID:30842730. |
we then examined the gene expression of several elements of the endocannabinoid system or different subunits of certain glutamatergic or gabaergic ionotropic receptors (ampa, nmda, or gaba |
2020-10-01 |
2023-08-13 |
rat |
| Seham Alaiyed, Katherine Conan. A Role for Matrix Metalloproteases in Antidepressant Efficacy. Frontiers in molecular neuroscience. vol 12. 2020-10-01. PMID:31133801. |
consistent with this possibility, the fast-acting antidepressant ketamine may act by selective inhibition of glutamatergic input to gaba releasing parvalbumin (pv)-expressing interneurons. |
2020-10-01 |
2023-08-13 |
human |
| Eiichi Kumamot. Cellular Mechanisms for Antinociception Produced by Oxytocin and Orexins in the Rat Spinal Lamina II-Comparison with Those of Other Endogenous Pain Modulators. Pharmaceuticals (Basel, Switzerland). vol 12. issue 3. 2020-10-01. PMID:31527474. |
oxytocin had no effect on glutamatergic excitatory transmission while producing a membrane depolarization, γ-aminobutyric acid (gaba)-ergic and glycinergic spontaneous inhibitory transmission enhancement. |
2020-10-01 |
2023-08-13 |
rat |
| Yuan Li, Xin Zhang, Lixin Chen, Bo Yang, Rubo Su. Cerebellar fastigial nucleus is involved in post-stroke depression through direct cerebellar-hypothalamic GABAergic and glutamatergic projections. Experimental and therapeutic medicine. vol 18. issue 4. 2020-10-01. PMID:31555378. |
the present study aimed to investigate whether the cerebellar fastigial nucleus (fn) is involved in post-stroke depression (psd), and to observe the effect of direct cerebellar-hypothalamic γ-aminobutyric acid (gaba)ergic and glutamatergic projections on psd, in order to understand the mechanisms underlying the cerebellar modulation of mood and emotion. |
2020-10-01 |
2023-08-13 |
rat |
| Istvan Mod. The GAD-given Right of Dentate Gyrus Granule Cells to Become GABAergic. Epilepsy currents. vol 2. issue 5. 2020-09-29. PMID:15309121. |
do neurons possess a janus face when it comes to neurotransmitters, or a given neuron is to be forever solely gamma-aminobutyric acid (gaba) ergic, glutamatergic, dopaminergic, peptidergic, or yourpreferredtransmitterergic? |
2020-09-29 |
2023-08-12 |
Not clear |
| Maxs Méndez-Ruette, Sergio Linsambarth, Rodrigo Moraga-Amaro, Daisy Quintana-Donoso, Luis Méndez, Giovanni Tamburini, Francisca Cornejo, Rodrigo F Torres, Jimmy Stehber. The Role of the Rodent Insula in Anxiety. Frontiers in physiology. vol 10. 2020-09-29. PMID:30984021. |
here, we set out to investigate the role of the rodent insula in anxiety by either inactivating different insular regions via microinjections of glutamatergic ampa receptor antagonist cnqx or activating them by microinjection of gaba receptor antagonist bicuculline in rats, before measuring anxiety-like behavior using the elevated plus maze. |
2020-09-29 |
2023-08-13 |
human |
| Alexandra A Naumova, Ekaterina A Oleynik, Elena V Chernigovskaya, Margarita V Glazov. Glutamatergic Fate of Neural Progenitor Cells of Rats with Inherited Audiogenic Epilepsy. Brain sciences. vol 10. issue 5. 2020-09-28. PMID:32455746. |
we found principal differences between wistar and km npc in unstimulated controls: wistar npc culture contained both gamma-aminobutyric acid (gaba) and glutamatergic neurons; km npc culture was mainly represented by glutamatergic cells. |
2020-09-28 |
2023-08-13 |
rat |
| Yilan Xu, Manna Zhao, Yuying Han, Heng Zhan. GABAergic Inhibitory Interneuron Deficits in Alzheimer's Disease: Implications for Treatment. Frontiers in neuroscience. vol 14. 2020-09-28. PMID:32714136. |
however, gamma-aminobutyric acid (gaba) inhibitory interneurons are resistant to aβ deposition, and aβ decreases synaptic glutamatergic transmission to decrease neural network activity. |
2020-09-28 |
2023-08-13 |
Not clear |
| Smriti Mongia, Tsuyoshi Yamaguchi, Bing Liu, Shiliang Zhang, Huiling Wang, Marisela Morale. The Ventral Tegmental Area has calbindin neurons with the capability to co-release glutamate and dopamine into the nucleus accumbens. The European journal of neuroscience. vol 50. issue 12. 2020-09-23. PMID:31215698. |
the ventral tegmental area (vta) has three major classes of neurons: dopaminergic (expressing tyrosine hydroxylase; th), gabaergic (expressing vesicular gaba transporter; vgat) and glutamatergic (expressing vesicular glutamate transporter 2; vglut2). |
2020-09-23 |
2023-08-13 |
rat |
| Morgane Chiesa, Damien Guimond, Roman Tyzio, Alexandre Pons-Bennaceur, Natalia Lozovaya, Nail Burnashev, Diana C Ferrari, Yehezkel Ben-Ar. Term or Preterm Cesarean Section Delivery Does Not Lead to Long-term Detrimental Consequences in Mice. Cerebral cortex (New York, N.Y. : 1991). vol 29. issue 6. 2020-09-22. PMID:29771287. |
moreover, c-section delivery neither alters the gamma-aminobutyric acid (gaba) developmental excitatory to inhibitory shift nor the frequency or amplitude of glutamatergic and gabaergic postsynaptic currents in hippocampal pyramidal neurons. |
2020-09-22 |
2023-08-13 |
mouse |
| Zoltán Molnár, Gavin J Clowry, Nenad Šestan, Ayman Alzu'bi, Trygve Bakken, Robert F Hevner, Petra S Hüppi, Ivica Kostović, Pasko Rakic, E S Anton, David Edwards, Patricia Garcez, Anna Hoerder-Suabedissen, Arnold Kriegstei. New insights into the development of the human cerebral cortex. Journal of anatomy. vol 235. issue 3. 2020-09-11. PMID:31373394. |
new views were discussed on the specification of glutamatergic pyramidal and γ-aminobutyric acid (gaba)ergic interneurons. |
2020-09-11 |
2023-08-13 |
human |