| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yong-Yu Yin, Yun-Hui Wang, Wen-Gang Liu, Jun-Qi Yao, Jin Yuan, Ze-Han Li, Yu-Hua Ran, Li-Ming Zhang, Yun-Feng L. The role of the excitation:inhibition functional balance in the mPFC in the onset of antidepressants. Neuropharmacology. vol 191. 2021-06-23. PMID:33945826. |
the balance between excitatory glutamatergic pyramidal neurons and inhibitory γ-aminobutyric acid (gaba) interneurons, i.e., the excitation:inhibition functional (e:i) balance, in the medial prefrontal cortex (mpfc) is critical in regulating several behaviors and might play an important mediating role in the mechanism of rapid antidepressant-like action reported by several studies. |
2021-06-23 |
2023-08-13 |
rat |
| Li Wang, Zhijian Zhang, Jiacheng Chen, Anne Manyande, Rafi Haddad, Qing Liu, Fuqiang X. Cell-Type-Specific Whole-Brain Direct Inputs to the Anterior and Posterior Piriform Cortex. Frontiers in neural circuits. vol 14. 2021-06-10. PMID:32116571. |
here, we mapped the whole-brain direct inputs to the two major neuronal populations, the excitatory glutamatergic principal neurons and inhibitory γ-aminobutyric acid (gaba)-ergic interneurons within the apc and ppc using the rabies virus (rv)-mediated retrograde trans-synaptic tracing system. |
2021-06-10 |
2023-08-13 |
Not clear |
| Sung-Su Park, Da-Hye Lee, So Min Lee, Chang Ho Lee, So Young Ki. Noise exposure alters MMP9 and brevican expression in the rat primary auditory cortex. BMC neuroscience. vol 21. issue 1. 2021-06-08. PMID:32334536. |
the expression levels of vesicular glutamatergic transporter (vglut)1, vglut2, vesicular gaba transporter (vgat), glutamate decarboxylase (gad)67, brevican, aggrecan, mmp9, and mmp14 were evaluated using real-time reverse transcription polymerase chain reaction or western blot. |
2021-06-08 |
2023-08-13 |
rat |
| Aniello Lombardi, Peter Jedlicka, Heiko J Luhmann, Werner Kil. Coincident glutamatergic depolarizations enhance GABAA receptor-dependent Cl- influx in mature and suppress Cl- efflux in immature neurons. PLoS computational biology. vol 17. issue 1. 2021-05-14. PMID:33465082. |
these computational experiments demonstrated that glutamatergic co-stimulation enhances gaba receptor-mediated cl- influx at low and attenuates or reverses the cl- efflux at high initial [cl-]i. |
2021-05-14 |
2023-08-13 |
Not clear |
| Farhan Augustine, Shreenath Rajendran, Harvey S Singe. Cortical endogenous opioids and their role in facilitating repetitive behaviors in deer mice. Behavioural brain research. vol 379. 2021-04-30. PMID:31676208. |
one postulated cortical mechanism, supported by our findings, is an opioid effect on cortical interneuron gaba release and a consequent effect on glutamatergic cortical pyramidal cells. |
2021-04-30 |
2023-08-13 |
mouse |
| Li-Yuan Chen, Maxime Lévesque, Massimo Avol. KCC2 antagonism and gabaergic synchronization in the entorhinal cortex in the absence of ionotropic glutamatergic receptor signalling. Neuropharmacology. vol 167. 2021-04-23. PMID:32014449. |
γ-aminobutyric acid (gaba), which is released by interneurons, plays an active role in generating interictal epileptiform spikes during blockade of ionotropic glutamatergic signalling, but it remains unclear whether and how the k |
2021-04-23 |
2023-08-13 |
Not clear |
| Kirsten Borup Bojesen, Brian Villumsen Broberg, Birgitte Fagerlund, Kasper Jessen, Marie Bjerregaard Thomas, Anne Sigvard, Karen Tangmose, Mette Ødegaard Nielsen, Gitte Saltoft Andersen, Henrik Bo Wiberg Larsson, Richard A E Edden, Egill Rostrup, Birte Yding Glenthø. Associations Between Cognitive Function and Levels of Glutamatergic Metabolites and Gamma-Aminobutyric Acid in Antipsychotic-Naïve Patients With Schizophrenia or Psychosis. Biological psychiatry. vol 89. issue 3. 2021-04-23. PMID:32928500. |
associations between cognitive function and levels of glutamatergic metabolites and gamma-aminobutyric acid in antipsychotic-naïve patients with schizophrenia or psychosis. |
2021-04-23 |
2023-08-13 |
Not clear |
| Kirsten Borup Bojesen, Brian Villumsen Broberg, Birgitte Fagerlund, Kasper Jessen, Marie Bjerregaard Thomas, Anne Sigvard, Karen Tangmose, Mette Ødegaard Nielsen, Gitte Saltoft Andersen, Henrik Bo Wiberg Larsson, Richard A E Edden, Egill Rostrup, Birte Yding Glenthø. Associations Between Cognitive Function and Levels of Glutamatergic Metabolites and Gamma-Aminobutyric Acid in Antipsychotic-Naïve Patients With Schizophrenia or Psychosis. Biological psychiatry. vol 89. issue 3. 2021-04-23. PMID:32928500. |
however, the association between cognitive function and levels of glutamatergic metabolites and gaba has not been investigated in a large group of antipsychotic-naïve patients. |
2021-04-23 |
2023-08-13 |
Not clear |
| S Andrea Wijtenburg, Jeffrey West, Stephanie A Korenic, Franchesca Kuhney, Frank E Gaston, Hongji Chen, Laura M Rowlan. Multimodal Neuroimaging Study of Visual Plasticity in Schizophrenia. Frontiers in psychiatry. vol 12. 2021-04-21. PMID:33868055. |
an fmri visual plasticity paradigm was implemented, and proton magnetic resonance spectroscopy data were acquired to determine whether baseline resting levels of glutamatergic and gaba metabolites were related to visual plasticity response. |
2021-04-21 |
2023-08-13 |
human |
| Farzaneh Saebi Rad, Abbas Haghparast, Afsaneh Eliass. Ventral Tegmental Area Microinjected-SKF38393 Increases Regular Chow Intake in 18 Hours Food-Deprived Rats. Basic and clinical neuroscience. vol 11. issue 6. 2021-04-16. PMID:33850614. |
ventral tegmental area (vta) dopamine neurons play an important role in reward mechanisms of food intake, and vta dopamine receptors exist on the terminal of glutamatergic and gabaergic neurons and regulate gamma-aminobutyric acid (gaba) and glutamate release. |
2021-04-16 |
2023-08-13 |
rat |
| Ryoki Sasaki, Naofumi Otsuru, Shota Miyaguchi, Sho Kojima, Hiraku Watanabe, Ken Ohno, Noriko Sakurai, Naoki Kodama, Daisuke Sato, Hideaki Onish. Influence of Brain-Derived Neurotrophic Factor Genotype on Short-Latency Afferent Inhibition and Motor Cortex Metabolites. Brain sciences. vol 11. issue 3. 2021-04-13. PMID:33804682. |
furthermore, the considerable inter-individual variability in inhibitory network activity typically measured by tms may be affected not only by gaba but also by other pathways, including glutamatergic and cholinergic activities; therefore, we used 3-t magnetic resonance spectroscopy (mrs) to measure the dynamics of glutamate plus glutamine (glx) and choline concentrations in the left m1, left somatosensory cortex, and right cerebellum. |
2021-04-13 |
2023-08-13 |
human |
| Koen Cuypers, Anouk Marsma. Transcranial magnetic stimulation and magnetic resonance spectroscopy: Opportunities for a bimodal approach in human neuroscience. NeuroImage. vol 224. 2021-03-29. PMID:32987106. |
particularly the mrs-detectable metabolites glutamate, the major excitatory neurotransmitter, and gamma-aminobutyric acid (gaba), the major inhibitory neurotransmitter, are of interest when combining tms and mrs. tms is a non-invasive brain stimulation technique that can be applied either as a neuromodulation or neurostimulation tool, specifically targeting glutamatergic and gabaergic mechanisms. |
2021-03-29 |
2023-08-13 |
human |
| Nikolay N Dygalo, Tatyana S Kalinina, Galina T Shishkin. Stress-induced expression pattern of glutamate signaling genes associated with anhedonia. Stress (Amsterdam, Netherlands). vol 23. issue 6. 2021-03-24. PMID:32814471. |
the decrease in expression of these subunits in the midbrain may attenuate glutamatergic drive on the serotonergic neurons promoting a shift of excitation/inhibition balance between glutamate and gaba in the forebrain regions resulting in anhedonia. |
2021-03-24 |
2023-08-13 |
human |
| E Komali, Ch Venkataramaiah, W Rajendr. Antiepileptic potential of Journal of traditional and complementary medicine. vol 11. issue 2. 2021-03-18. PMID:33728274. |
antiepileptic potential of epilepsy is a chronic central nervous system disorder that occurs not only with the imbalance of glutamatergic neurons and inhibitory gamma-aminobutyric acid (γ-gaba) neurons, but also with abnormal central cholinergic neuronal regulation. |
2021-03-18 |
2023-08-13 |
Not clear |
| Dusan Hirjak, Katharina M Kubera, R Christian Wolf, Georg Northof. Going Back to Kahlbaum's Psychomotor (and GABAergic) Origins: Is Catatonia More Than Just a Motor and Dopaminergic Syndrome? Schizophrenia bulletin. vol 46. issue 2. 2021-02-08. PMID:31361896. |
in contrast, studies relying on ncrs found rather aberrant higher-order frontoparietal networks which, biochemically, are insufficiently modulated by gamma-aminobutyric acid (gaba)-ergic and glutamatergic transmission. |
2021-02-08 |
2023-08-13 |
Not clear |
| Yan Jin, Qian Meng, Lisheng Mei, Wenjie Zhou, Xia Zhu, Yu Mao, Wen Xie, Xulai Zhang, Min-Hua Luo, Wenjuan Tao, Haitao Wang, Jie Li, Juan Li, Xiangyao Li, Zhi Zhan. A somatosensory cortex input to the caudal dorsolateral striatum controls comorbid anxiety in persistent pain. Pain. vol 161. issue 2. 2021-02-02. PMID:31651582. |
using viral neuronal tracing in mice, we identified a previously unknown pathway whereby glutamatergic neurons from layer 5 of the hindlimb primary somatosensory cortex (s1) (glu), a well-known brain region involved in pain processing, project to gabaergic neurons in the caudal dorsolateral striatum (gaba). |
2021-02-02 |
2023-08-13 |
mouse |
| Kenichi Adachi, Daisuke Kato, Tomoaki Kahyo, Tomokazu Konishi, Toyohiro Sato, Yuta Madokoro, Masayuki Mizuno, Hiroyasu Akatsu, Mitsutoshi Setou, Noriyuki Matsukaw. Possible correlated variation of GABA Biochemical and biophysical research communications. vol 542. 2021-02-02. PMID:33503541. |
possible correlated variation of gaba cholinergic neural activation from the medial septal nucleus to hippocampus plays a crucial role in episodic memory as a regulating system for glutamatergic neural activation in the hippocampus. |
2021-02-02 |
2023-08-13 |
mouse |
| Kouji Fukuyama, Masashi Fukuzawa, Takashi Shiroyama, Motohiro Okad. Pathomechanism of nocturnal paroxysmal dystonia in autosomal dominant sleep-related hypermotor epilepsy with S284L-mutant α4 subunit of nicotinic ACh receptor. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 126. 2021-01-26. PMID:32169758. |
the activation of α4β2-nachr in the rtn increased gaba release in motn resulting in reduced glutamatergic transmission in thalamic hyperdirect pathway of wild-type. |
2021-01-26 |
2023-08-13 |
human |
| Alana Witt Hansen, Felipe Borges Almeida, Solange Bandiera, Rianne Remus Pulcinelli, Greice Caletti, Grasiela Agnes, Leonardo Fernandes de Paula, Natália Azuaga Nietiedt, Maurício Schüler Nin, Helena Maria Tannhauser Barros, Rosane Gome. Correlations between subunits of GABA Alcohol (Fayetteville, N.Y.). vol 82. 2021-01-12. PMID:31473305. |
correlations between subunits of gaba chronic use of alcohol and its withdrawal impairs the delicate balance between gabaergic and glutamatergic systems. |
2021-01-12 |
2023-08-13 |
Not clear |
| Christopher K Salmon, Horia Pribiag, Claire Gizowski, W Todd Farmer, Scott Cameron, Emma V Jones, Vivek Mahadevan, Charles W Bourque, David Stellwagen, Melanie A Woodin, Keith K Mura. Depolarizing GABA Transmission Restrains Activity-Dependent Glutamatergic Synapse Formation in the Developing Hippocampal Circuit. Frontiers in cellular neuroscience. vol 14. 2021-01-10. PMID:32161521. |
depolarizing gaba transmission restrains activity-dependent glutamatergic synapse formation in the developing hippocampal circuit. |
2021-01-10 |
2023-08-13 |
Not clear |