| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shuyue Cheng, Jingjing Xu, Wei Wang, Rui Wang, Haonan Li, Zhijun Jiang, Dexiang Liu, Fang Pa. Inhibition of mGluR5 alters BDNF/TrkB and GLT-1 expression in the prefrontal cortex and hippocampus and ameliorates PTSD-like behavior in rats. Psychopharmacology. 2023-02-01. PMID:36725696. |
previous studies have shown that traumatic stress changes metabotropic glutamate receptor 5 (mglur5) expression in the hippocampus (hip) and prefrontal cortex (pfc). |
2023-02-01 |
2023-08-14 |
rat |
| Jia Guo, Douglas L Rothman, Scott A Smal. Why Hippocampal Glutamate Levels Are Elevated in Schizophrenia. JAMA psychiatry. 2023-01-25. PMID:36696108. |
why hippocampal glutamate levels are elevated in schizophrenia. |
2023-01-25 |
2023-08-14 |
Not clear |
| Zhinei Tan, Yongxia Li, Yinzheng Guan, Javed Iqbal, Chenyue Wang, Riqiang Yan, Xin-Ming M. Klotho Regulated by Estrogen Plays a Key Role in Sex Differences in Stress Resilience in Rats. International journal of molecular sciences. vol 24. issue 2. 2023-01-21. PMID:36674721. |
our results showed that kl is regulated by estrogen in rat hippocampal neurons in vivo and in vitro and is essential for the estrogen-mediated increase in the number of presynaptic vesicular glutamate transporter 1 (vglut1)-positive clusters on the dendrites of hippocampal neurons. |
2023-01-21 |
2023-08-14 |
rat |
| Qin-Wei Wu, Zheng-Quan Tan. Focusing on the Emerging Role of Kainate Receptors in the Dorsal Cochlear Nucleus (DCN) and Cerebellum. International journal of molecular sciences. vol 24. issue 2. 2023-01-21. PMID:36675230. |
kainate receptors (kars) are one class of the glutamate receptor family and are strongly expressed in the hippocampus, the cerebellum, and cerebellum-like structures. |
2023-01-21 |
2023-08-14 |
Not clear |
| Anant Jain, Catherine S Woolle. Mechanisms that underlie expression of estradiol-induced excitatory synaptic potentiation in the hippocampus differ between males and females. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-01-17. PMID:36650060. |
here, we used electrical stimulation and two-photon glutamate uncaging in hippocampal slices from adult male and female rats to investigate whether the downstream consequences of distinct molecular signaling remain different between the sexes or converge to the same mechanism(s) of expression of potentiation. |
2023-01-17 |
2023-08-14 |
rat |
| Javad Karimi Abadchi, Zahra Rezaei, Thomas Knöpfel, Bruce L McNaughton, Majid H Mohajeran. Inhibition is a prevalent mode of activity in the neocortex around awake hippocampal ripples in mice. eLife. vol 12. 2023-01-16. PMID:36645126. |
we addressed this possibility by conducting voltage and glutamate wide-field imaging of the neocortex with concurrent hippocampal electrophysiology in awake mice. |
2023-01-16 |
2023-08-14 |
mouse |
| Yoon Ji Kwon, Sojeong Pak, Sunggu Yang, Sungchil Yan. Electrophysiological measurements of synaptic connectivity and plasticity in the longitudinal dentate gyrus network from mouse hippocampal slices. STAR protocols. vol 4. issue 1. 2023-01-12. PMID:36633949. |
we detail the steps for (1) obtaining acute mouse hippocampal slices that contain longitudinal dg-dg connections, (2) measuring excitatory postsynaptic potentials using whole-cell patch clamp recording combined with two-photon microscopy and glutamate uncaging, and (3) assessing synaptic plasticity using extracellular field recording. |
2023-01-12 |
2023-08-14 |
mouse |
| Yuchen Hao, Estelle Toulmé, Benjamin König, Christian Rosenmund, Andrew J R Pleste. Targeted sensors for glutamatergic neurotransmission. eLife. vol 12. 2023-01-09. PMID:36622100. |
chimeras of stargazin and gamma-8 that we named snfr-γ2 and snfr-γ8, were enriched at synapses, retained function and reported spontaneous glutamate release in rat hippocampal cells, with apparently diffraction-limited spatial precision. |
2023-01-09 |
2023-08-14 |
mouse |
| Tatyana Y Postnikova, Dmitry V Amakhin, Alina M Trofimova, Natalia L Tumanova, Nadezhda M Dubrovskaya, Daria S Kalinina, Anna A Kovalenko, Anastasiia D Shcherbitskaia, Dmitry S Vasilev, Aleksey V Zaitse. Maternal Hyperhomocysteinemia Produces Memory Deficits Associated with Impairment of Long-Term Synaptic Plasticity in Young Rats. Cells. vol 12. issue 1. 2023-01-08. PMID:36611852. |
no significant alterations of glutamate receptor subunit expression except glun1 were detected in the hippocampus of hcy rats using the quantitative real-time pcr and western blot methods. |
2023-01-08 |
2023-08-14 |
rat |
| Mohammad Keimasi, Kowsar Salehifard, Marzieh Shahidi, Fariba Esmaeili, Noushin Mirshah Jafar Esfahani, Siamak Beheshti, Mohammadreza Amirsadri, Faezeh Naseri, Mohammadjavad Keimasi, Najmeh Ghorbani, Mohammad Reza Mofid, Majid Moradman. Ameliorative effects of omega-lycotoxin-Gsp2671e purified from the spider venom of Frontiers in pharmacology. vol 13. 2023-01-02. PMID:36588719. |
this condition can be induced by hyper-stimulation of n-methyl-d-aspartate receptors (nmdars) of glutamate in the hippocampus, which ends up to pyramidal neurons determination. |
2023-01-02 |
2023-08-14 |
spider |
| Sukrit Promtang, Chairat Turbpaiboon, Eve Mon Oo, Ladawan Khowawisetsut, Panapat Uawithya, Supin Chompoopon. Germinated brown rice protects against glutamate toxicity in HT22 hippocampal neurons through the jnk-mediated apoptotic pathway via the GABA IBRO neuroscience reports. vol 14. 2023-01-02. PMID:36590249. |
germinated brown rice protects against glutamate toxicity in ht22 hippocampal neurons through the jnk-mediated apoptotic pathway via the gaba the anti-apoptosis effect of germinated brown rice (gbr) focusing on differentiated ht22 cells results in improved nutritional values after the germination process of gbr which contains total phenolic compounds and γ-aminobutyric acid (gaba). |
2023-01-02 |
2023-08-14 |
Not clear |
| Stefania Dimonte, Vladyslav Sikora, Maria Bove, Maria Grazia Morgese, Paolo Tucci, Stefania Schiavone, Luigia Trabac. Social isolation from early life induces anxiety-like behaviors in adult rats: Relation to neuroendocrine and neurochemical dysfunctions. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 158. 2023-01-02. PMID:36592494. |
no significant differences were found in noradrenaline and serotonin levels, as well as in serotonin turnover in hippocampus, while glutamate amount was increased and gaba levels were reduced in isolated rats. |
2023-01-02 |
2023-08-14 |
human |
| Yiyi Li, Hongyu Chen, Jianhao Wang, Jiabei Wang, Xuan Niu, Chao Wang, Dongdong Qin, Fang Li, Yamei Wang, Jing Xiong, Songyan Liu, Liqin Huang, Xi Zhang, Feng Gao, Dandan Gao, Mingxia Fan, Xuan Xiao, Zhi-Hao Wan. Inflammation-activated C/EBPβ mediates high-fat diet-induced depression-like behaviors in mice. Frontiers in molecular neuroscience. vol 15. 2022-12-29. PMID:36578534. |
furthermore, hfd impaired synaptic plasticity and decreased surface expression of glutamate receptors in the hippocampus of wild-type (wt) mice, but not in c/ebpβ heterozygous knockout mice. |
2022-12-29 |
2023-08-14 |
mouse |
| Yingying Jiang, Qingying Liu, Yumei Zhao, Chunyang Wang, Ming Su. Activation of CREB-BDNF Pathway in Pyramidal Neurons in the Hippocampus Improves the Neurological Outcome of Mice with Ischemic Stroke. Molecular neurobiology. 2022-12-26. PMID:36571720. |
however, it is unclear whether glutamate in the ventral hippocampal cornus ammonis 1 (vca1) acts a part in neurological deficits, pain perception, anxiety, and depression induced by ischemic stroke. |
2022-12-26 |
2023-08-14 |
mouse |
| Xiao-Hui Tang, Yu-Gang Diao, Zhuo-Yu Ren, Yan-Yu Zang, Guang-Fen Zhang, Xing-Ming Wang, Gui-Fang Duan, Jin-Chun Shen, Kenji Hashimoto, Zhi-Qiang Zhou, Jian-Jun Yan. A role of GABA Neuropharmacology. 2022-12-24. PMID:36565851. |
mice exposed to fss (forced swimming stress) showed depression-like behavior and decreased levels of gaba (γ-aminobutyric acid), but not glutamate, in the hippocampus. |
2022-12-24 |
2023-08-14 |
mouse |
| Xiao-Hui Tang, Yu-Gang Diao, Zhuo-Yu Ren, Yan-Yu Zang, Guang-Fen Zhang, Xing-Ming Wang, Gui-Fang Duan, Jin-Chun Shen, Kenji Hashimoto, Zhi-Qiang Zhou, Jian-Jun Yan. A role of GABA Neuropharmacology. 2022-12-24. PMID:36565851. |
ketamine increased gaba levels and decreased glutamate levels in the hippocampus of mice exposed to fss. |
2022-12-24 |
2023-08-14 |
mouse |
| Ahmed Salim Mahmood, Afaq M Ammoo, Mayssam Hussein Mohammed Ali, Tiba M Hameed, Hany A Al-Hussaniy, Abdulla Amer Abbas Aljumaili, Mohammed Hussein Alaa Al-Fallooji, Ali Hakim Kadhi. Antiepileptic Effect of Neuroaid Pharmaceuticals (Basel, Switzerland). vol 15. issue 12. 2022-12-23. PMID:36558919. |
brain specimens from surviving animals were extracted and examined pathologically for quantification of glutamate receptor (glur) gene expression in the isolated hippocampus employing real-time pcr analysis. |
2022-12-23 |
2023-08-14 |
mouse |
| Ling Zhang, Yu-Zhu Gao, Chun-Jie Zhao, Jiang-Yan Xia, Jian-Jun Yang, Mu-Huo J. Reduced inhibitory and excitatory input onto parvalbumin interneurons mediated by perineuronal net might contribute to cognitive impairments in a mouse model of sepsis-associated encephalopathy. Neuropharmacology. 2022-12-21. PMID:36543316. |
the densities of vesicular γ-aminobutyric acid transporter, vesicular glutamate transporter 1, pnn, and parvalbumin (pv) in the hippocampus were evaluated by immunofluorescence. |
2022-12-21 |
2023-08-14 |
mouse |
| Jongyun Myeong, Vitaly A Klyachk. Rapid astrocyte-dependent facilitation amplifies multi-vesicular release in hippocampal synapses. Cell reports. vol 41. issue 11. 2022-12-14. PMID:36516768. |
using near-total internal reflection fluorescence (near-tirf) imaging of single vesicle release in cultured hippocampal synapses, we demonstrate a distinctive, release-dependent form of facilitation in which probability of vesicle release is higher following a successful glutamate release event than following a failure. |
2022-12-14 |
2023-08-14 |
Not clear |
| Laura Bellingacci, Martina Tallarico, Andrea Mancini, Alfredo Megaro, Carmen De Caro, Rita Citraro, Giovambattista De Sarro, Alessandro Tozzi, Massimiliano Di Filippo, Miriam Sciaccaluga, Emilio Russo, Antonio Leo, Cinzia Cost. Non-competitive AMPA glutamate receptors antagonism by perampanel as a strategy to counteract hippocampal hyper-excitability and cognitive deficits in cerebral amyloidosis. Neuropharmacology. 2022-12-12. PMID:36502868. |
non-competitive ampa glutamate receptors antagonism by perampanel as a strategy to counteract hippocampal hyper-excitability and cognitive deficits in cerebral amyloidosis. |
2022-12-12 |
2023-08-14 |
mouse |