| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiao-Qian Zhang, Xiao-Yin Wang, Bing-Chao Dong, Mei-Xuan Li, Yu Wang, Ting Xiao, Shan-Shan Zha. C-X-C chemokine receptor type 7 antibody enhances neural plasticity after ischemic stroke. Neural regeneration research. vol 18. issue 9. 2023-03-17. PMID:36926722. |
our results showed that cxcr7-neutralizing antibody increased the total length and number of sprouting corticospinal tract fibers in rats with cerebral ischemia, increased the expression of vesicular glutamate transporter 1 and growth-related protein 43, markers of the denervated spinal cord synapses, and promoted the differentiation and maturation of oligodendrocyte progenitor cells in the striatum. |
2023-03-17 |
2023-08-14 |
rat |
| Sarah Amato, Monica Averna, Diego Guidolin, Cristina Ceccoli, Elena Gatta, Simona Candiani, Marco Pedrazzi, Michela Capraro, Guido Maura, Luigi F Agnati, Chiara Cervetto, Manuela Marcol. Heteromerization of Dopamine D2 and Oxytocin Receptor in Adult Striatal Astrocytes. International journal of molecular sciences. vol 24. issue 5. 2023-03-11. PMID:36902106. |
in conclusion, roles for astrocytic d2-otr in the control of glutamatergic synapse functioning through modulation of astrocytic glutamate release should be taken into consideration when considering interactions between oxytocinergic and dopaminergic systems in striatum. |
2023-03-11 |
2023-08-14 |
rat |
| Nao Chuhma, Soo Jung Oh, Stephen Raypor. The dopamine neuron synaptic map in the striatum. Cell reports. vol 42. issue 3. 2023-03-03. PMID:36867530. |
dopamine neurons project to the striatum to control movement, cognition, and motivation via slower volume transmission as well as faster dopamine, glutamate, and gaba synaptic actions capable of conveying the temporal information in dopamine neuron firing. |
2023-03-03 |
2023-08-14 |
Not clear |
| Aeseul Kim, Sun Mi Gu, Haemiru Lee, Dong Eun Kim, Jin Tae Hong, Jaesuk Yun, Hye Jin Ch. Prenatal ketamine exposure impairs prepulse inhibition via arginine vasopressin receptor 1A-mediated GABAergic neuronal dysfunction in the striatum. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 160. 2023-02-04. PMID:36738499. |
in the striatum of offspring, ketamine or methoxetamine treatment increased glutamate decarboxylase 67 (gad67) and δ-aminobutyric acid (gaba) levels. |
2023-02-04 |
2023-08-14 |
rat |
| Li-Min Mao, Nirav Mathur, John Q Wan. An allosteric potentiator of metabotropic glutamate (mGlu) 2 receptors reduces the cocaine-stimulated ERK1/2 phosphorylation in the mouse striatum. Neuroscience letters. 2022-12-24. PMID:36565803. |
an allosteric potentiator of metabotropic glutamate (mglu) 2 receptors reduces the cocaine-stimulated erk1/2 phosphorylation in the mouse striatum. |
2022-12-24 |
2023-08-14 |
mouse |
| Nicolette Stogios, Laurie Hamel, Emily Smith, Marcos Sanches, Gary Remington, Aristotle Voineskos, Satya Dash, Ariel Graff-Guerrero, Margaret Hahn, Sri Mahavir Agarwa. Investigating the effects of antipsychotics on brain insulin action: Study protocol for a multi-modality magnetic resonance imaging (MRI) study in healthy controls. PloS one. vol 17. issue 11. 2022-11-28. PMID:36441736. |
it is hypothesized that: 1) intranasal insulin (ini), but not intranasal placebo (inp), will change cerebral blood flow and resting state connectivity, as well as increase glutamate levels in the striatum and dorsolateral prefrontal cortex; 2) oral olanzapine (ola), but not oral placebo (pl), will inhibit the effect of ini on these parameters. |
2022-11-28 |
2023-08-14 |
human |
| Ana Carolina Pinheiro Campos, Raquel Chacon Ruiz Martinez, Aline Vivian Vatti Auada, Ivo Lebrun, Erich Talamoni Fonoff, Clement Hamani, Rosana Lima Pagan. Effect of Subthalamic Stimulation and Electrode Implantation in the Striatal Microenvironment in a Parkinson's Disease Rat Model. International journal of molecular sciences. vol 23. issue 20. 2022-10-27. PMID:36292973. |
the pd rat model exhibited akinesia, increased inflammation, glutamate release, and decreased glutamatergic clearance in the striatum. |
2022-10-27 |
2023-08-14 |
rat |
| Oriane Onimus, Emmanuel Valjent, Gilberto Fisone, Giuseppe Gangaross. Haloperidol-Induced Immediate Early Genes in Striatopallidal Neurons Requires the Converging Action of cAMP/PKA/DARPP-32 and mTOR Pathways. International journal of molecular sciences. vol 23. issue 19. 2022-10-14. PMID:36232936. |
taking advantage of transgenic mouse models, pharmacological approaches and immunofluorescence analyses, we found that haloperidol-induced iegs in the striatum required the synergistic activation of a2a (adenosine) and nmda (glutamate) receptors. |
2022-10-14 |
2023-08-14 |
mouse |
| Emma Muñoz-Moreno, Rui Vasco Simões, Raúl Tudela, Xavier López-Gil, Guadalupe Sori. Spatio-temporal metabolic rewiring in the brain of TgF344-AD rat model of Alzheimer's disease. Scientific reports. vol 12. issue 1. 2022-10-10. PMID:36216838. |
compared to wt, tgf344-ad rats replicated common findings in ad patients, including decreased n-acetylaspartate in the cortex, hippocampus and thalamus, and decreased glutamate in the thalamus and striatum. |
2022-10-10 |
2023-08-14 |
rat |
| Viktor A Stratilov, Oleg V Vetrovoy, Ekaterina I Tyulkov. Prenatal Hypoxia Affects Nicotine Consumption and Withdrawal in Adult Rats via Impairment of the Glutamate System in the Brain. Molecular neurobiology. 2022-05-17. PMID:35581520. |
psh rats also demonstrated an increased level of phosphorylated darpp-32 protein (known as the relay for dopamine and glutamate signaling) at 34 threonine (pthr34darpp-32) in relation to its total amount in the nucleus accumbens of the striatum (nac). |
2022-05-17 |
2023-08-13 |
rat |
| Ruixue Yu, Wenqing Yang, Dongmei Qi, Lili Gong, Chao Li, Yunlun Li, Haiqiang Jian. Targeted neurotransmitter metabolomics profiling of oleanolic acid in the treatment of spontaneously hypertensive rats. RSC advances. vol 9. issue 40. 2022-05-06. PMID:35514525. |
oa could effectively restore tyrosine metabolism in the striatum and hypothalamus, glutamate metabolism in the hippocampus, striatum and temporal lobe, cholinergic metabolism in the striatum, and histidine metabolism in the hypothalamus due to its inhibition of inflammatory reactions, structural damage of the neuronal cells, and increase in sedative activity. |
2022-05-06 |
2023-08-13 |
rat |
| Gregory G Grecco, Braulio Muñoz, Gonzalo Viana Di Prisco, Emma H Doud, Brandon M Fritz, Danielle Maulucci, Yong Gao, Amber L Mosley, Anthony J Baucum, Brady K Atwoo. Prenatal opioid exposure impairs endocannabinoid and glutamate transmission in the dorsal striatum. eNeuro. 2022-04-09. PMID:35396255. |
we previously demonstrated that opioids have deleterious effects on endocannabinoid plasticity at glutamate synapses in the dorsal striatum of adolescent rodents, but it is unclear if prenatal opioid exposure produces similar neuroadaptations. |
2022-04-09 |
2023-08-13 |
mouse |
| Davin R Peart, Allyson K Andrade, Carly N Logan, Lori A Knackstedt, Jennifer E Murra. Regulation of Cocaine-related Behaviors by Estrogen and Progesterone. Neuroscience and biobehavioral reviews. 2022-02-21. PMID:35189163. |
these opposing effects of 17ß-estradiol and progesterone/allopregnanolone involve endocannabinoid, γ-aminobutyric acid, dopamine, and glutamate transmission in the medial prefrontal cortex and striatum. |
2022-02-21 |
2023-08-13 |
rat |
| Megan L Shipman, Laura H Corbi. Diet-induced deficits in goal-directed control are rescued by agonism of group II metabotropic glutamate receptors in the dorsomedial striatum. Translational psychiatry. vol 12. issue 1. 2022-01-29. PMID:35091538. |
diet-induced deficits in goal-directed control are rescued by agonism of group ii metabotropic glutamate receptors in the dorsomedial striatum. |
2022-01-29 |
2023-08-13 |
rat |
| Jordyn M Wilcox, David C Consoli, Krista C Paffenroth, Brittany D Spitznagel, Erin S Calipari, Aaron B Bowman, Fiona E Harriso. Manganese-induced hyperactivity and dopaminergic dysfunction depend on age, sex and YAC128 genotype. Pharmacology, biochemistry, and behavior. 2022-01-22. PMID:35063467. |
the same exposure paradigm led to decreased dopamine and serotonin and metabolites (3-mt, hva and 5-hiaa) in striatum and increased glutamate in yac128 mice but not wt mice. |
2022-01-22 |
2023-08-13 |
mouse |
| Ornela Kljakic, Helena Janíčková, Miguel Skirzewski, Amy Reichelt, Sara Memar, Salah El Mestikawy, Yulong Li, Lisa M Saksida, Timothy J Bussey, Vania F Prado, Marco A M Prad. Functional dissociation of behavioral effects from acetylcholine and glutamate released from cholinergic striatal interneurons. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36. issue 2. 2022-01-15. PMID:35032355. |
in the striatum, cholinergic interneurons (cins) have the ability to release both acetylcholine and glutamate, due to the expression of the vesicular acetylcholine transporter (vacht) and the vesicular glutamate transporter 3 (vglut3). |
2022-01-15 |
2023-08-13 |
mouse |
| Marie-Charlotte Allichon, Vanesa Ortiz, Paula Pousinha, Andry Andrianarivelo, Anna Petitbon, Nicolas Heck, Pierre Trifilieff, Jacques Barik, Peter Vanhoutt. Cell-Type-Specific Adaptions in Striatal Medium-Sized Spiny Neurons and Their Roles in Behavioral Responses to Drugs of Abuse. Frontiers in synaptic neuroscience. vol 13. 2021-12-31. PMID:34970134. |
within the reward circuitry, the striatum is a key target structure of drugs of abuse since it is at the crossroad of converging glutamate inputs from limbic, thalamic and cortical regions, encoding components of drug-associated stimuli and environment, and dopamine that mediates reward prediction error and incentive values. |
2021-12-31 |
2023-08-13 |
Not clear |
| Przemysław Cieśla. Glutamate receptors in the dopamine system – function and role in reinforcement learning Postepy biochemii. vol 67. issue 3. 2021-12-11. PMID:34894387. |
glutamate receptors in the dopamine system – function and role in reinforcement learning midbrain dopamine neurons along with the major target of their projections, dopaminoceptive neurons in striatum, regulate reinforcement learning and motivation. |
2021-12-11 |
2023-08-13 |
mouse |
| Makoto Kimura, Yasunori Oda, Yuki Hirose, Hiroshi Kimura, Kouhei Yoshino, Tomihisa Niitsu, Nobuhisa Kanahara, Yukihiko Shirayama, Kenji Hashimoto, Masaomi Iy. Upregulation of heat-shock protein HSP-70 and glutamate transporter-1/glutamine synthetase in the striatum and hippocampus in haloperidol-induced dopamine-supersensitivity-state rats. Pharmacology, biochemistry, and behavior. vol 211. 2021-12-06. PMID:34653399. |
upregulation of heat-shock protein hsp-70 and glutamate transporter-1/glutamine synthetase in the striatum and hippocampus in haloperidol-induced dopamine-supersensitivity-state rats. |
2021-12-06 |
2023-08-13 |
rat |
| Alice Egerton, Anna Murphy, Jacek Donocik, Adriana Anton, Gareth J Barker, Tracy Collier, Bill Deakin, Richard Drake, Emma Eliasson, Richard Emsley, Catherine J Gregory, Kira Griffiths, Shitij Kapur, Laura Kassoumeri, Laura Knight, Emily J B Lambe, Stephen M Lawrie, Jane Lees, Shôn Lewis, David J Lythgoe, Julian Matthews, Philip McGuire, Lily McNamee, Scott Semple, Alexander D Shaw, Krish D Singh, Charlotte Stockton-Powdrell, Peter S Talbot, Mattia Veronese, Ernest Wagner, James T R Walters, Stephen R Williams, James H MacCabe, Oliver D Howe. Dopamine and Glutamate in Antipsychotic-Responsive Compared With Antipsychotic-Nonresponsive Psychosis: A Multicenter Positron Emission Tomography and Magnetic Resonance Spectroscopy Study (STRATA). Schizophrenia bulletin. vol 47. issue 2. 2021-11-22. PMID:32910150. |
1h-magnetic resonance spectroscopy (1h-mrs) was used to measure glutamate levels (glucorr) in the acc and in the right striatum in 92 patients across 4 sites (48 responders [r] and 44 nonresponders [nr]). |
2021-11-22 |
2023-08-13 |
Not clear |