All Relations between glutamate and striatum

Publication Sentence Publish Date Extraction Date Species
Wiebke Bensmann, Nicolas Zink, Annett Werner, Christian Beste, Ann-Kathrin Stoc. Acute Alcohol Effects on Response Inhibition Depend on Response Automatization, but not on GABA or Glutamate Levels in the ACC and Striatum. Journal of clinical medicine. vol 9. issue 2. 2020-09-28. PMID:32050509. we used mr spectroscopy to assess baseline (i.e., sober) gaba and glutamate levels in the anterior cingulate cortex (acc) and striatum in 2020-09-28 2023-08-13 Not clear
Tasmia Hai, Hanna Duffy, Jean-Francois Lemay, Rose Swansburg, Emma A Climie, Frank P MacMaste. Neurochemical Correlates of Executive Function in Children with Attention-Deficit/Hyperactivity Disorder. Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent. vol 29. issue 1. 2020-09-28. PMID:32194648. the objectives of this study were 1) to investigate spectroscopic biomarkers in the right prefrontal cortex (r-pfc) and left striatum; 2) to evaluate executive function (ef) performance; and, 3) to examine the clinical relevance of glutamate in ef tasks. 2020-09-28 2023-08-13 Not clear
Wen Zhang, Wenjing Yu, Xiaofang Liu, Qian Wang, Xue Bai, Xia Cui, Sumei Wan. Effect of Jian-Pi-Zhi-Dong Decoction on the Amino Acid Neurotransmitters in a Rat Model of Tourette Syndrome and Comorbid Anxiety Disorder. Frontiers in psychiatry. vol 11. 2020-09-28. PMID:32581885. we measured the content of glutamate (glu) and γ-aminobutyric acid (gaba) both in the serum and striatum and the expression of their receptors by western blot and real-time polymerase chain reaction. 2020-09-28 2023-08-13 rat
Ellen T Koch, Lynn A Raymon. Dysfunctional striatal dopamine signaling in Huntington's disease. Journal of neuroscience research. vol 97. issue 12. 2020-08-21. PMID:31304622. studies of hd patients and genetic rodent models have shown changes to levels of dopamine and its receptors in the striatum, and alterations in dopamine receptor signaling and modulation of other neurotransmitters, notably glutamate. 2020-08-21 2023-08-13 mouse
Maxime Fouyssac, David Beli. Beyond drug-induced alteration of glutamate homeostasis, astrocytes may contribute to dopamine-dependent intrastriatal functional shifts that underlie the development of drug addiction: A working hypothesis. The European journal of neuroscience. vol 50. issue 6. 2020-08-12. PMID:30968489. capitalising on growing evidence that astrocytes play a fundamental regulatory role in glutamate and dopamine transmission in the striatum, we present an innovative model of a quadripartite synaptic microenvironment within which astrocytes channel functional interactions between the dopaminergic and glutamatergic systems that may represent the primary striatal functional unit that undergoes drug-induced adaptations eventually leading to addiction. 2020-08-12 2023-08-13 Not clear
Ritchy Hodebourg, Jennifer E Murray, Maxime Fouyssac, Mickaël Puaud, Barry J Everitt, David Beli. Heroin seeking becomes dependent on dorsal striatal dopaminergic mechanisms and can be decreased by N-acetylcysteine. The European journal of neuroscience. vol 50. issue 3. 2020-06-30. PMID:29514413. while cocaine reinforcement depends on the mesolimbic system, well-established cocaine seeking is dependent on dorsolateral striatum (adls) dopamine-dependent mechanisms which are disrupted by n-acetylcysteine, through normalisation of corticostriatal glutamate homeostasis. 2020-06-30 2023-08-13 rat
Seyed-Alireza Hassani, Sofia Lendor, Ezel Boyaci, Janusz Pawliszyn, Thilo Womelsdor. Multineuromodulator measurements across fronto-striatal network areas of the behaving macaque using solid-phase microextraction. Journal of neurophysiology. vol 122. issue 4. 2020-06-17. PMID:31433731. reliable measurements of glutamate, dopamine, acetylcholine, and choline were made simultaneously within frontal cortex and striatum of two macaque monkeys ( 2020-06-17 2023-08-13 monkey
Amanda L Blaker, Elizabeth R Moore, Bryan K Yamamot. Serial exposure to ethanol drinking and methamphetamine enhances glutamate excitotoxicity. Journal of neurochemistry. vol 151. issue 6. 2020-06-11. PMID:31478210. etoh drinking decreased the glutamate aspartate transporter and increased basal extracellular concentrations of glutamate within the striatum when measured after the last day of drinking. 2020-06-11 2023-08-13 rat
Amanda L Blaker, Elizabeth R Moore, Bryan K Yamamot. Serial exposure to ethanol drinking and methamphetamine enhances glutamate excitotoxicity. Journal of neurochemistry. vol 151. issue 6. 2020-06-11. PMID:31478210. etoh drinking also exacerbated the acute increases in extracellular glutamate observed upon meth exposure, the subsequent increases in spectrin proteolysis, and the long-term decreases in dopamine content in the striatum, all of which were attenuated by ceftriaxone administration during etoh drinking only. 2020-06-11 2023-08-13 rat
Marc Deffains, Hagai Bergma. Parkinsonism-related β oscillations in the primate basal ganglia networks - Recent advances and clinical implications. Parkinsonism & related disorders. vol 59. 2020-03-16. PMID:30578010. today, the basal ganglia (bg) network can be viewed as a three-layer neural network in which the striatum and the subthalamic nucleus (stn) are the two bg input structures and together innervate bg downstream structures using gaba and glutamate, respectively. 2020-03-16 2023-08-13 Not clear
Jian Le, Zebin Lin, Lin Song, Hao Wang, Zhanying Hon. LC-MS/MS combined with in vivo microdialysis sampling from conscious rat striatum for simultaneous determination of active constituents of Yuanhu- Baizhi herb pair and endogenous neurotransmitters: Application to pharmacokinetic and pharmacodynamic study. Journal of pharmaceutical and biomedical analysis. vol 176. 2020-03-10. PMID:31404799. a lc-ms/ms method combined with in vivo microdialysis sampling from awaken rats' striatum was developed to simultaneously quantitate three endogenous neurotransmitters, dopamine(da), glutamate (glu), and 5-hydroxytryptamine (5-ht), and nine components of yuanhu-baizhi herb pair in rats. 2020-03-10 2023-08-13 rat
Gabriele Schele. Logarithmic distributions prove that intrinsic learning is Hebbian. F1000Research. vol 6. 2020-03-09. PMID:29071065. the difference between strongly recurrent and feed-forward connectivity (cortex vs. striatum and cerebellum), neurotransmitter (gaba (striatum) or glutamate (cortex)) or the level of activation (low in cortex, high in purkinje cells and midbrain nuclei) turns out to be irrelevant for this feature. 2020-03-09 2023-08-13 Not clear
Arndt von Twickel, Daniel Kowatschew, Mehmet Saltürk, Maria Schauer, Brita Robertson, Sigrun Korsching, Wolfgang Walkowiak, Sten Grillner, Juan Pérez-Fernánde. Individual Dopaminergic Neurons of Lamprey SNc/VTA Project to Both the Striatum and Optic Tectum but Restrict Co-release of Glutamate to Striatum Only. Current biology : CB. vol 29. issue 4. 2020-03-03. PMID:30713108. individual dopaminergic neurons of lamprey snc/vta project to both the striatum and optic tectum but restrict co-release of glutamate to striatum only. 2020-03-03 2023-08-13 Not clear
Arndt von Twickel, Daniel Kowatschew, Mehmet Saltürk, Maria Schauer, Brita Robertson, Sigrun Korsching, Wolfgang Walkowiak, Sten Grillner, Juan Pérez-Fernánde. Individual Dopaminergic Neurons of Lamprey SNc/VTA Project to Both the Striatum and Optic Tectum but Restrict Co-release of Glutamate to Striatum Only. Current biology : CB. vol 29. issue 4. 2020-03-03. PMID:30713108. the combined release of dopamine and glutamate may be appropriate in striatum, whereas the effects exerted on the tectal motor center may be better served with a selective dopaminergic modulation. 2020-03-03 2023-08-13 Not clear
Stefanie Perl, Franziska Richter, Birthe Gericke, Angelika Richte. Expression of metabotropic glutamate 5 receptors in the striatum and cortex and effects of modulators on the severity of dystonia in the phenotypic dt European journal of pharmacology. vol 859. 2020-01-28. PMID:31283933. expression of metabotropic glutamate 5 receptors in the striatum and cortex and effects of modulators on the severity of dystonia in the phenotypic dt the metabotropic glutamate 5 (mglu 2020-01-28 2023-08-13 Not clear
b' Lei Liu, Mary K Vollmer, Abdullah S Ahmad, Victoria M Fernandez, Hocheol Kim, Sylvain Dor\\xc3\\xa. Pretreatment with Korean red ginseng or dimethyl fumarate attenuates reactive gliosis and confers sustained neuroprotection against cerebral hypoxic-ischemic damage by an Nrf2-dependent mechanism. Free radical biology & medicine. vol 131. 2020-01-21. PMID:30458277.' in both ischemic striatum and cortex, the dynamic pattern of attenuated reactive gliosis in astrocytes and microglia, including affected astrocytic dysfunction in glutamate metabolism and water homeostasis, correlated well with the nrf2-dependent neuroprotection by ginseng or dmf. 2020-01-21 2023-08-13 mouse
Yun Zhou, Bjørnar Hassel, Tore Eid, Niels Christian Danbol. Axon-terminals expressing EAAT2 (GLT-1; Slc1a2) are common in the forebrain and not limited to the hippocampus. Neurochemistry international. vol 123. 2019-12-26. PMID:29530756. although synapsin 1-cre mediated gene deletion only reduced the forebrain tissue content of eaat2 protein to 95.5 ± 3.4% of wild-type (littermate) controls, the glutamate accumulation in homogenates of neocortex, hippocampus, striatum and thalamus were nevertheless diminished to, respectively, 54 ± 4, 46 ± 3, 46 ± 2 and 65 ± 7% of controls (average ± sem, n = 3 pairs of littermates). 2019-12-26 2023-08-13 mouse
Robert B Laprairie, Geraldine T Petr, Yan Sun, Kathryn D Fischer, Eileen M Denovan-Wright, Paul A Rosenber. Huntington's disease pattern of transcriptional dysregulation in the absence of mutant huntingtin is produced by knockout of neuronal GLT-1. Neurochemistry international. vol 123. 2019-12-26. PMID:29709465. glt-1 is the major glutamate transporter in the brain, and is expressed in astrocytes and in axon terminals in the hippocampus, cortex, and striatum. 2019-12-26 2023-08-13 Not clear
Kaixuan Shi, Xiaoli Liu, Lijuan Hou, Decai Qiao, Xiangming Li. Effects of exercise on mGluR-mediated glutamatergic transmission in the striatum of hemiparkinsonian rats. Neuroscience letters. vol 705. 2019-12-23. PMID:31029678. the results showed that hemiparkinsonian rats have a significant increase in extracellular glutamate levels in the lesioned-lateral striatum. 2019-12-23 2023-08-13 rat
Claudia Vingerhoets, Desmond H Y Tse, Therese van Amelsvoor. Riluzole effectively treats psychotic symptoms and improves cognition in 22q11.2 deletion syndrome: A clinical case. European journal of medical genetics. vol 62. issue 8. 2019-12-12. PMID:31229682. here we report acute (single dose) and long-term effects of riluzole on glutamate and gaba levels in the anterior cingulate cortex (acc) and striatum (measured with magnetic resonance spectroscopy, 1h-mrs) as well as on psychotic symptoms and cognitive functioning in a medication-free 23-year old woman with 22q11ds. 2019-12-12 2023-08-13 Not clear