Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Kazuki Sugaya, Tomotaka Misawa, Makoto Onodera, Ken Isek. Serotonin syndrome treated with cyproheptadine using NPi from a digital pupillometer as a therapeutic indicator: A case report. Medicine. vol 103. issue 15. 2024-04-12. PMID:38608060. |
serotonin syndrome treated with cyproheptadine using npi from a digital pupillometer as a therapeutic indicator: a case report. |
2024-04-12 |
2024-04-15 |
Not clear |
Kazuki Sugaya, Tomotaka Misawa, Makoto Onodera, Ken Isek. Serotonin syndrome treated with cyproheptadine using NPi from a digital pupillometer as a therapeutic indicator: A case report. Medicine. vol 103. issue 15. 2024-04-12. PMID:38608060. |
based on the hypothesis that neurological pupil index (npi) on a digital pupil recorder would correlate with the severity of the serotonin syndrome, we administered cyproheptadine using npi as an indicator. |
2024-04-12 |
2024-04-15 |
Not clear |
Ahmed Bada. Serotonin syndrome: An often-neglected medical emergency. Journal of family & community medicine. vol 31. issue 1. 2024-02-26. PMID:38406216. |
in severe cases, benzodiazepines may be used to control agitation and muscle rigidity, while serotonin antagonists, such as cyproheptadine, may be used to reduce serotonin levels. |
2024-02-26 |
2024-02-28 |
Not clear |
Ahmed Nagy, Aishah Nasir, Mahfujul Haque, Ramzan Judge, Joseph Le. Therapeutic cyproheptadine regimen in serotonin syndrome: Complications after cardiovascular surgery. Clinical case reports. vol 11. issue 7. 2023-07-21. PMID:37476598. |
therapeutic cyproheptadine regimen in serotonin syndrome: complications after cardiovascular surgery. |
2023-07-21 |
2023-08-14 |
Not clear |
Ahmed Nagy, Aishah Nasir, Mahfujul Haque, Ramzan Judge, Joseph Le. Therapeutic cyproheptadine regimen in serotonin syndrome: Complications after cardiovascular surgery. Clinical case reports. vol 11. issue 7. 2023-07-21. PMID:37476598. |
this report describes the use of cyproheptadine for the management of serotonin syndrome in a patient taking fluoxetine and bupropion, who received methylene blue for vasoplegia syndrome. |
2023-07-21 |
2023-08-14 |
Not clear |
Ahmed Nagy, Aishah Nasir, Mahfujul Haque, Ramzan Judge, Joseph Le. Therapeutic cyproheptadine regimen in serotonin syndrome: Complications after cardiovascular surgery. Clinical case reports. vol 11. issue 7. 2023-07-21. PMID:37476598. |
cyproheptadine and supportive care were used successfully to treat serotonin syndrome, and the patient was discharged home 14 days postoperatively. |
2023-07-21 |
2023-08-14 |
Not clear |
Ahmed Nagy, Aishah Nasir, Mahfujul Haque, Ramzan Judge, Joseph Le. Therapeutic cyproheptadine regimen in serotonin syndrome: Complications after cardiovascular surgery. Clinical case reports. vol 11. issue 7. 2023-07-21. PMID:37476598. |
based on the literature, there is no standardized method of weaning cyproheptadine when used for serotonin syndrome. |
2023-07-21 |
2023-08-14 |
Not clear |
Tobias Hölle, Jan C Purrucker, Benedict Morath, Markus A Weigand, Felix C F Schmit. [Central anticholinergic, neuroleptic malignant and serotonin syndromes]. Wiener klinisches Magazin : Beilage zur Wiener klinischen Wochenschrift. vol 26. issue 3. 2023-05-30. PMID:37251531. |
for serotonin syndrome an initial dose of 12 mg cyproheptadine followed by 2 mg every 2 h is recommended (maximum 32 mg/day or 0.5 mg/kgbw day |
2023-05-30 |
2023-08-14 |
Not clear |
Tobias Hölle, Jan C Purrucker, Benedict Morath, Markus A Weigand, Felix C F Schmit. [Central anticholinergic, neuroleptic malignant and serotonin syndromes : Important differential diagnoses in postoperative impairment of consciousness]. Die Anaesthesiologie. 2023-02-17. PMID:36799968. |
for serotonin syndrome an initial dose of 12 mg cyproheptadine followed by 2 mg every 2 h is recommended (maximum 32 mg/day or 0.5 mg/kgbw day |
2023-02-17 |
2023-08-14 |
Not clear |
Georg A Petroian. Hyperthermia and Serotonin: The Quest for a "Better Cyproheptadine". International journal of molecular sciences. vol 23. issue 6. 2022-03-25. PMID:35328784. |
hyperthermia and serotonin: the quest for a "better cyproheptadine". |
2022-03-25 |
2023-08-13 |
Not clear |
Georg A Petroian. Hyperthermia and Serotonin: The Quest for a "Better Cyproheptadine". International journal of molecular sciences. vol 23. issue 6. 2022-03-25. PMID:35328784. |
while a compound with such an ideal profile is presently not available, better matches than the conventional antidote cyproheptadine (used off-label in severe serotonin syndrome cases) appear to be possible and need to be identified. |
2022-03-25 |
2023-08-13 |
Not clear |
M Carmen Louzao, Celia Costas, Paula Abal, Toshiyuki Suzuki, Ryuichi Watanabe, Natalia Vilariño, Cristina Carrera, Andrea Boente-Juncal, Carmen Vale, Mercedes R Vieytes, Luis M Botan. Serotonin involvement in okadaic acid-induced diarrhoea in vivo. Archives of toxicology. vol 95. issue 8. 2021-11-12. PMID:34148100. |
on the contrary, the serotonin antagonist cyproheptadine was able to block (10 mg/kg) or delay (0.1 and 1 mg/kg) diarrhoea onset suggesting a role of 5-ht. |
2021-11-12 |
2023-08-13 |
mouse |
Daniel Maia Nogueira de Oliveira, Carlos Alberto Oliveira-Silva, Camila Gadelha Pinheiro, Emanuella Feitosa de Carvalho, Kalinne Kelly Lima Gadelha, Karine Lima-Silva, Ana Karolina Martins Cavalcante, Mônica de Oliveira Belém, Suliana Mesquita Paula, Armênio Aguiar Dos Santos, Pedro Jorge Caldas Magalhãe. Differential effects of β-methylphenylethylamine and octopamine on contractile parameters of the rat gastrointestinal tract. European journal of pharmacology. vol 908. 2021-08-20. PMID:34265293. |
the contractile effect of β-mpea was reduced by cyproheptadine and methiothepin, antagonists of excitatory 5-ht receptors. |
2021-08-20 |
2023-08-13 |
rat |
Sanjay Prakash, Deepali Lodha, Kalu Singh Rawa. Coexistence of serotonin syndrome and neuroleptic malignant syndrome: does it exist? BMJ case reports. vol 14. issue 8. 2021-08-18. PMID:34400419. |
a diagnosis of serotonin syndrome (ss) was made, and cyproheptadine was started. |
2021-08-18 |
2023-08-13 |
Not clear |
Erica Schlichting, Chris Welter, Tammi Schaeffer, Tania D Strou. Serotonin Syndrome Associated With Vilazodone Overdose in a 22-Month-Old Treated With Dexmedetomidine. The Journal of emergency medicine. vol 60. issue 2. 2021-07-08. PMID:33158691. |
serotonin syndrome classically manifests with restlessness, hyperthermia, tachycardia, mydriasis, and increased tone, and is typically treated with benzodiazepines, cyproheptadine, and supportive care. |
2021-07-08 |
2023-08-13 |
Not clear |
Brian P Murray, Joseph E Carpenter, Joshua Sayers, Michael Yeh, Jordan Beau, Emily A Kiernan, Matthew J Wolf, Tonya A Bolton, Ziad Kazz. Two Cases of Serotonin Syndrome After Bupropion Overdose Treated With Cyproheptadine. The Journal of emergency medicine. vol 60. issue 4. 2021-07-08. PMID:33308914. |
two cases of serotonin syndrome after bupropion overdose treated with cyproheptadine. |
2021-07-08 |
2023-08-13 |
Not clear |
Brian P Murray, Joseph E Carpenter, Joshua Sayers, Michael Yeh, Jordan Beau, Emily A Kiernan, Matthew J Wolf, Tonya A Bolton, Ziad Kazz. Two Cases of Serotonin Syndrome After Bupropion Overdose Treated With Cyproheptadine. The Journal of emergency medicine. vol 60. issue 4. 2021-07-08. PMID:33308914. |
he was administered cyproheptadine for presumed serotonin syndrome with temporal improvement in his symptoms. |
2021-07-08 |
2023-08-13 |
Not clear |
Brian P Murray, Joseph E Carpenter, Joshua Sayers, Michael Yeh, Jordan Beau, Emily A Kiernan, Matthew J Wolf, Tonya A Bolton, Ziad Kazz. Two Cases of Serotonin Syndrome After Bupropion Overdose Treated With Cyproheptadine. The Journal of emergency medicine. vol 60. issue 4. 2021-07-08. PMID:33308914. |
in these cases, bupropion overdose resulted in a clinical presentation consistent with serotonin syndrome, with the first having a temporal improvement after treatment with cyproheptadine. |
2021-07-08 |
2023-08-13 |
Not clear |
Jan L Max. Serotonin Syndrome Following Terbutaline Administration in a Heart Transplant Patient on Multiple Inotropic Agents: A Case Report. Transplantation proceedings. vol 52. issue 9. 2021-02-11. PMID:32560969. |
administration of cyproheptadine, a known reversal agent for serotonin toxicity, rapidly alleviated the adverse symptoms. |
2021-02-11 |
2023-08-13 |
Not clear |
Jared R Frye, Andrew M Poggemiller, Patrick W McGonagill, Kate O Pape, Colette Galet, Yuk Ming Li. Use of Cyproheptadine for the Treatment of Serotonin Syndrome: A Case Series. Journal of clinical psychopharmacology. vol 40. issue 1. 2020-10-19. PMID:31860612. |
use of cyproheptadine for the treatment of serotonin syndrome: a case series. |
2020-10-19 |
2023-08-13 |
Not clear |