| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M V King, A J Sleight, M L Woolley, I A Topham, C A Marsden, K C F Fon. 5-HT6 receptor antagonists reverse delay-dependent deficits in novel object discrimination by enhancing consolidation--an effect sensitive to NMDA receptor antagonism. Neuropharmacology. vol 47. issue 2. 2004-09-28. PMID:15223298. |
5-ht(6) receptors are expressed in brain regions associated with learning and memory, and blockade of their function increases central cholinergic and glutamatergic neurotransmission and enhances cognitive processes. |
2004-09-28 |
2023-08-12 |
rat |
| M V King, A J Sleight, M L Woolley, I A Topham, C A Marsden, K C F Fon. 5-HT6 receptor antagonists reverse delay-dependent deficits in novel object discrimination by enhancing consolidation--an effect sensitive to NMDA receptor antagonism. Neuropharmacology. vol 47. issue 2. 2004-09-28. PMID:15223298. |
this suggests that the 5-ht(6) receptor antagonist-induced enhancement of consolidation involves increased central glutamatergic neurotransmission. |
2004-09-28 |
2023-08-12 |
rat |
| Maria Lüttgen, Sven Ove Ogren, Björn Meiste. Chemical identity of 5-HT2A receptor immunoreactive neurons of the rat septal complex and dorsal hippocampus. Brain research. vol 1010. issue 1-2. 2004-09-01. PMID:15126129. |
the results suggest that serotonin acting on 5-ht2a receptors can modulate hippocampal functions via direct actions on hippocampal glutamatergic principal cells and indirectly via actions on hippocampal interneurons with different phenotypes as well as gabaergic and cholinergic septohippocampal neurons. |
2004-09-01 |
2023-08-12 |
rat |
| Vitali A Bouryi, David I Lewi. The modulation by 5-HT of glutamatergic inputs from the raphe pallidus to rat hypoglossal motoneurones, in vitro. The Journal of physiology. vol 553. issue Pt 3. 2004-08-31. PMID:14555716. |
the modulation by 5-ht of glutamatergic inputs from the raphe pallidus to rat hypoglossal motoneurones, in vitro. |
2004-08-31 |
2023-08-12 |
rat |
| Vitali A Bouryi, David I Lewi. The modulation by 5-HT of glutamatergic inputs from the raphe pallidus to rat hypoglossal motoneurones, in vitro. The Journal of physiology. vol 553. issue Pt 3. 2004-08-31. PMID:14555716. |
these data demonstrate that raphe pallidus inputs to hypoglossal motoneurones are predominantly glutamatergic in nature, with 5-ht decreasing the release of glutamate from these projections as a result of activation of 5-ht1a and/or 5-ht1b receptors located on presynaptic terminals. |
2004-08-31 |
2023-08-12 |
rat |
| Ning Zhong, Vahri Beaumont, Robert S Zucke. Calcium influx through HCN channels does not contribute to cAMP-enhanced transmission. Journal of neurophysiology. vol 92. issue 1. 2004-08-24. PMID:15014107. |
serotonin is a native neuromodulator of synaptic transmission at glutamatergic neuromuscular junctions of crayfish limb muscles. |
2004-08-24 |
2023-08-12 |
Not clear |
| Patricia Gaspa. [Genetic models to understand how serotonin acts during development]. Journal de la Societe de biologie. vol 198. issue 1. 2004-07-19. PMID:15146951. |
expression of sert can however occur independently of tph during development and allows subpopulations of glutamatergic neurons to take up and to store 5-ht into synaptic vesicles via the vesicular monoamine transporter (vmat). |
2004-07-19 |
2023-08-12 |
mouse |
| F M M A van der Heijden, S Tuinier, D Fekkes, A E S Sijben, R S Kahn, W M A Verhoeve. Atypical antipsychotics and the relevance of glutamate and serotonin. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 14. issue 3. 2004-06-21. PMID:15056486. |
the results of this study suggest an effect of atypical antipsychotics on glutamatergic neurotransmission and an association between lower pretreatment peripheral 5-ht parameters and response. |
2004-06-21 |
2023-08-12 |
Not clear |
| G M Sparks, S Dasari, R L Coope. Actions of MDMA at glutamatergic neuromuscular junctions. Neuroscience research. vol 48. issue 4. 2004-05-12. PMID:15041196. |
in this study, mdma altered synaptic transmission presynaptically by enhancing quantal release in two model glutamatergic synapses-the neuromuscular junction (nmj) of the crayfish opener muscle, which is enhanced by exogenous 5-ht application, and the nmj of a larval body wall muscle in drosophila melanogaster, which is insensitive to exogenous 5-ht application. |
2004-05-12 |
2023-08-12 |
drosophila_melanogaster |
| Marie L Woolley, Charles A Marsden, Kevin C F Fon. 5-ht6 receptors. Current drug targets. CNS and neurological disorders. vol 3. issue 1. 2004-05-11. PMID:14965245. |
the 5-ht(6)receptor appears to regulate glutamatergic and cholinergic neuronal activity, and increasing evidence suggests that it may be involved in the regulation of cognition, feeding and, possibly, affective state and seizures. |
2004-05-11 |
2023-08-12 |
Not clear |
| Konrad Lehmann, Jörg Lesting, Dierk Polascheck, Gertraud Teuchert-Nood. Serotonin fibre densities in subcortical areas: differential effects of isolated rearing and methamphetamine. Brain research. Developmental brain research. vol 147. issue 1-2. 2004-05-03. PMID:14741759. |
with dopaminergic and glutamatergic afferents, must be taken into account when the seemingly uniform 5-ht projections are investigated. |
2004-05-03 |
2023-08-12 |
Not clear |
| J E Belforte, J H Paz. Turning behaviour induced by stimulation of the 5-HT receptors in the subthalamic nucleus. The European journal of neuroscience. vol 19. issue 2. 2004-03-18. PMID:14725629. |
furthermore, the partial blockade of glutamatergic receptors in the snr by the antagonist dnqx increased the contralateral circling elicited by stimulation of 5-ht receptors in the stn. |
2004-03-18 |
2023-08-12 |
rat |
| Shaul Feldman, Joseph Weidenfel. Involvement of endogeneous glutamate in the stimulatory effect of norepinephrine and serotonin on the hypothalamo-pituitary-adrenocortical axis. Neuroendocrinology. vol 79. issue 1. 2004-03-15. PMID:14755133. |
these results suggest that glutamatergic interneurons in the pvn, acting via non-nmda and nmda receptors, may act as an excitatory mechanism in the ne and 5-ht control of hypothalamic acth secretagogues. |
2004-03-15 |
2023-08-12 |
rat |
| Anna Czyrak, Klaudia Czepiel, Marzena Maćkowiak, Agnieszka Chocyk, Krzysztof Wedzon. Serotonin 5-HT1A receptors might control the output of cortical glutamatergic neurons in rat cingulate cortex. Brain research. vol 989. issue 1. 2003-12-12. PMID:14519510. |
serotonin 5-ht1a receptors might control the output of cortical glutamatergic neurons in rat cingulate cortex. |
2003-12-12 |
2023-08-12 |
rat |
| Nathalie Giroux, Connie Chau, Hugues Barbeau, Tomás A Reader, Serge Rossigno. Effects of intrathecal glutamatergic drugs on locomotion. II. NMDA and AP-5 in intact and late spinal cats. Journal of neurophysiology. vol 90. issue 2. 2003-10-01. PMID:12904502. |
it is proposed that the basic locomotor rhythmicity in cats is nmda-dependent and that normally this glutamatergic mechanism is modulated by other neurotransmitters, such as 5-ht and na. |
2003-10-01 |
2023-08-12 |
cat |
| Rita J Valentino, Vincent Bey, Luise Pernar, Kathryn G Common. Substance P Acts through local circuits within the rat dorsal raphe nucleus to alter serotonergic neuronal activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 18. 2003-09-09. PMID:12904475. |
the results suggest that nk1 receptor activation in the dr excites a population of 5-ht neurons via glutamatergic transmission. |
2003-09-09 |
2023-08-12 |
rat |
| Krystyna Gołembiowska, Anna Dziubin. Inhibition of amino acid release by 5-HT1B receptor agonist in the rat prefrontal cortex. Polish journal of pharmacology. vol 54. issue 6. 2003-08-15. PMID:12866717. |
we suggest that cortical glutamatergic neurons possess 5-ht1b heteroceptors and their activation may be responsible for the inhibitory effect of 5-ht on glu and asp release. |
2003-08-15 |
2023-08-12 |
rat |
| Robin L Cooper, Ahmet Dönmezer, Joseph Sheare. Intrinsic differences in sensitivity to 5-HT between high- and low-output terminals innervating the same target. Neuroscience research. vol 45. issue 2. 2003-04-10. PMID:12573463. |
charge) of spontaneous quantal currents indicate no difference in postsynaptic receptivity to the glutamatergic synaptic transmission upon exposure to 5-ht. |
2003-04-10 |
2023-08-12 |
Not clear |
| Lee A Dawson, Huy Q Nguyen, Ping L. Potentiation of amphetamine-induced changes in dopamine and 5-HT by a 5-HT(6) receptor antagonist. Brain research bulletin. vol 59. issue 6. 2003-04-04. PMID:12576149. |
although recent data has shown that 5-ht(6) receptor antagonists' can enhance basal cholinergic and glutamatergic neurotransmission in the cortex and hippocampus, the distribution of this receptor within terminal regions of the dopaminergic system suggests a possible role for this receptor in the modulation of dopamine (da). |
2003-04-04 |
2023-08-12 |
rat |
| Daniel Umbricht, Franz X Vollenweider, Liselotte Schmid, Claudia Grübel, Anja Skrabo, Theo Huber, Rene Kolle. Effects of the 5-HT2A agonist psilocybin on mismatch negativity generation and AX-continuous performance task: implications for the neuropharmacology of cognitive deficits in schizophrenia. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 1. 2003-03-17. PMID:12496954. |
in contrast, secondary pharmacological effects shared by nmdar antagonists and the 5-ht(2a) agonist (ie disruption of glutamatergic neurotransmission) may be the mechanism underlying impairments in ax-cpt performance observed during both psilocybin and ketamine administration. |
2003-03-17 |
2023-08-12 |
human |