Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
K E Andersso. Advances in the pharmacological control of the bladder. Experimental physiology. vol 84. issue 1. 1999-05-04. PMID:10081718. |
potentially, drugs affecting gaba, opioid, 5-ht, noradrenaline, dopamine, or glutamatergic receptors and mechanisms can be developed, but a selective action on the lower urinary tract may be difficult to obtain. |
1999-05-04 |
2023-08-12 |
human |
S Bertrand, J R Cazalet. Presynaptic GABAergic control of the locomotor drive in the isolated spinal cord of neonatal rats. The European journal of neuroscience. vol 11. issue 2. 1999-04-21. PMID:10051758. |
when locomotor like activity was induced by bath applying a mixture of n-methyl-d-l-aspartate and serotonin to the l1-l2 segments, intracellular recordings of l3-l5 motoneurons show an alternating pattern of monosynaptic excitatory glutamatergic and inhibitory glycinergic inputs known as the locomotor drive. |
1999-04-21 |
2023-08-12 |
rat |
G J Marek, G K Aghajania. The electrophysiology of prefrontal serotonin systems: therapeutic implications for mood and psychosis. Biological psychiatry. vol 44. issue 11. 1999-03-23. PMID:9836015. |
instead, 5-ht appears to act presynaptically, directly or indirectly, to induce a focal release of glutamate from a subpopulation of glutamatergic terminals impinging upon the apical (but not basilar) dendrites of layer v pyramidal cells; a working hypothesis of the transduction pathway (involving asynchronous transmitter release) for this process is presented. |
1999-03-23 |
2023-08-12 |
Not clear |
G E Stutzmann, B S McEwen, J E LeDou. Serotonin modulation of sensory inputs to the lateral amygdala: dependency on corticosterone. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 22. 1998-12-11. PMID:9801389. |
thus, the ability of 5-ht to modulate glutamatergic activity in auditory pathways to the amygdala is dependent on the presence of cort and possibly glucocorticoid activation. |
1998-12-11 |
2023-08-12 |
rat |
Y W Li, D A Baylis. Presynaptic inhibition by 5-HT1B receptors of glutamatergic synaptic inputs onto serotonergic caudal raphe neurones in rat. The Journal of physiology. vol 510 ( Pt 1). 1998-09-01. PMID:9625871. |
in addition, the frequency of spontaneous glutamatergic miniature epscs was diminished by cp-93,129 and paired-pulse facilitation of epscs was enhanced by 5-ht. |
1998-09-01 |
2023-08-12 |
rat |
Y W Li, D A Baylis. Presynaptic inhibition by 5-HT1B receptors of glutamatergic synaptic inputs onto serotonergic caudal raphe neurones in rat. The Journal of physiology. vol 510 ( Pt 1). 1998-09-01. PMID:9625871. |
these data indicate that serotonergic caudal raphe neurones receive glutamatergic inputs that are inhibited by presynaptic 5-ht1b receptors; inhibition of excitatory synapses onto raphe cells may represent a novel mechanism for autoregulation of serotonergic neuronal activity by 5-ht. |
1998-09-01 |
2023-08-12 |
rat |
P Li, M Zhu. Silent glutamatergic synapses and nociception in mammalian spinal cord. Nature. vol 393. issue 6686. 1998-07-01. PMID:9641681. |
serotonin (5-hydroxytryptamine, 5-ht), an important neurotransmitter of the raphe-spinal projecting pathway, transforms silent glutamatergic synapses into functional ones. |
1998-07-01 |
2023-08-12 |
Not clear |
K Krebs-Thomson, V Lehmann-Masten, S Naiem, M P Paulus, M A Geye. Modulation of phencyclidine-induced changes in locomotor activity and patterns in rats by serotonin. European journal of pharmacology. vol 343. issue 2-3. 1998-06-09. PMID:9570460. |
to test the hypothesis that serotonergic modulation of the effects of phencyclidine (pcp) are due to circuit- rather than receptor-based interactions between glutamatergic and serotonergic systems, multivariate profiles of rat behavior were assessed after treatments with the 5-hydroxytryptamine (5-ht) 5-ht2 receptor antagonist ketanserin (1.0 mg/kg), the 5-ht2 receptor agonist (1(2,5-dimethoxy-4-iodophenyl)-2-aminopropane) (doi; 0.27 mg/kg), various doses of pcp (0.75 to 10.125 mg/kg), or combinations thereof. |
1998-06-09 |
2023-08-12 |
rat |
E Pearlstein, F Clarac, D Cattaer. Neuromodulation of reciprocal glutamatergic inhibition between antagonistic motoneurons by 5-hydroxytryptamine (5-HT) in crayfish walking system. Neuroscience letters. vol 241. issue 1. 1998-04-28. PMID:9502210. |
neuromodulation of reciprocal glutamatergic inhibition between antagonistic motoneurons by 5-hydroxytryptamine (5-ht) in crayfish walking system. |
1998-04-28 |
2023-08-12 |
Not clear |
F Licata, G Li Volsi, L Ciranna, G Maugeri, F Santangel. 5-Hydroxytryptamine modifies neuronal responses to glutamate in the red nucleus of the rat. Experimental brain research. vol 118. issue 1. 1998-04-15. PMID:9547078. |
these results suggest that 5-ht is able to modulate the motor glutamatergic input to rn by acting mostly on non-nmda receptors. |
1998-04-15 |
2023-08-12 |
rat |
J H Singer, M C Bellingham, A J Berge. Presynaptic inhibition of glutamatergic synaptic transmission to rat motoneurons by serotonin. Journal of neurophysiology. vol 76. issue 2. 1998-03-16. PMID:8871200. |
presynaptic inhibition of glutamatergic synaptic transmission to rat motoneurons by serotonin. |
1998-03-16 |
2023-08-12 |
rat |
J H Singer, M C Bellingham, A J Berge. Presynaptic inhibition of glutamatergic synaptic transmission to rat motoneurons by serotonin. Journal of neurophysiology. vol 76. issue 2. 1998-03-16. PMID:8871200. |
serotonin (5-ht) inhibited glutamatergic synaptic transmission in a dose-dependent fashion as indicated by a reduction in the evoked epsc (eepsc) peak amplitude to 46 +/- 2% (mean +/- se, n = 26) of control (5-ht 10 microm). |
1998-03-16 |
2023-08-12 |
rat |
J H Singer, M C Bellingham, A J Berge. Presynaptic inhibition of glutamatergic synaptic transmission to rat motoneurons by serotonin. Journal of neurophysiology. vol 76. issue 2. 1998-03-16. PMID:8871200. |
we conclude that 5-ht, acting through presynaptic 5-ht1b receptors, inhibits glutamatergic synaptic transmission by reducing the probability of vesicle release. |
1998-03-16 |
2023-08-12 |
rat |
S Sugama, N Shimokawa, J Okada, M Miur. In vitro study of H+-sensitive neurons in the ventral medullary surface of neonate rats. Brain research. vol 777. issue 1-2. 1998-02-24. PMID:9449417. |
the h+-sensitive neurons in the vms showed positive immunoreactivity to glutamate (57%, 17/30) and glutamic acid decarboxylase (23%, 7/30), but no immunoreactivity to choline acetyltransferase, tyrosine hydroxylase, phenylethanolamine n-methyltransferase, somatostatin, serotonin and substance p. these results indicate that the h+-sensitive neurons are present specifically in the vms, and are mainly glutamatergic and gabaergic. |
1998-02-24 |
2023-08-12 |
rat |
A E Dooley, I S Pappas, J G Parnavela. Serotonin promotes the survival of cortical glutamatergic neurons in vitro. Experimental neurology. vol 148. issue 1. 1998-01-07. PMID:9398462. |
serotonin promotes the survival of cortical glutamatergic neurons in vitro. |
1998-01-07 |
2023-08-12 |
rat |
G K Aghajanian, G J Mare. Serotonin induces excitatory postsynaptic potentials in apical dendrites of neocortical pyramidal cells. Neuropharmacology. vol 36. issue 4-5. 1997-09-15. PMID:9225284. |
the epscs could be induced rapidly by the microiontophoresis of 5-ht directly to "hot spots" within the apical (but not basilar) dendritic field of recorded neurons, indicating that excitatory amino acids may be released by a ttx-sensitive focal action of 5-ht on a subset of glutamatergic terminals in this region. |
1997-09-15 |
2023-08-12 |
rat |
M Marcoli, G Maura, M Tortarolo, M Raiter. Serotonin inhibition of the NMDA receptor/nitric oxide/cyclic GMP pathway in rat cerebellum: involvement of 5-hydroxytryptamine2C receptors. Journal of neurochemistry. vol 69. issue 1. 1997-07-24. PMID:9202339. |
previous studies have shown that 5-hydroxytryptamine (5-ht) can potently inhibit glutamatergic transmission in rat cerebellum through the activation of multiple 5-ht receptors. |
1997-07-24 |
2023-08-12 |
rat |
M Bijak, U Misgel. Effects of serotonin through serotonin1A and serotonin4 receptors on inhibition in the guinea-pig dentate gyrus in vitro. Neuroscience. vol 78. issue 4. 1997-07-22. PMID:9174070. |
the effects of serotonin (5-hydroxytryptamine) on hilar neurons and on inhibitory postsynaptic potentials in granule cells were compared using intracellular recording in the presence of glutamatergic receptor antagonists. |
1997-07-22 |
2023-08-12 |
Not clear |
A Meneses, E Hon. A pharmacological analysis of serotonergic receptors: effects of their activation of blockade in learning. Progress in neuro-psychopharmacology & biological psychiatry. vol 21. issue 2. 1997-06-05. PMID:9061774. |
furthermore, the role of 5-ht receptors in learning seem to require an interaction with glutamatergic, gabaergic and cholinergic neurotransmission systems. |
1997-06-05 |
2023-08-12 |
Not clear |
J H Singer, A J Berge. Presynaptic inhibition by serotonin: a possible mechanism for switching motor output of the hypoglossal nucleus. Sleep. vol 19. issue 10 Suppl. 1997-05-30. PMID:9085495. |
our data demonstrate that 5-ht acts presynaptically to inhibit excitatory (glutamatergic) synaptic currents recorded in hms. |
1997-05-30 |
2023-08-12 |
Not clear |