| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Thomas Roskoden, Karl Zilles, Axel Schleicher, Herbert Schwegle. Transient postnatal thyroxine treatment leads to variation in transmitter binding site densities in the hippocampus of rats. Neuroscience letters. vol 333. issue 1. 2002-12-26. PMID:12401551. |
in the adult animals we measured the densities of glutamatergic (n-methyl-d-aspartate (nmda), amino-3-hydroxy-5-methylisoxazole-4-propionic acid (ampa), kainic acid (ka)), cholinergic (muscarinic subtype 1 and 2 (m1, m2)), gamma-aminobutyric acid (gaba)ergic (gaba(a)) and serotonergic (5-hydroxytryptamine (5-ht(1a))) binding sites using quantitative receptor-autoradiography with tritiated ligands. |
2002-12-26 |
2023-08-12 |
rat |
| Rui Tao, Sidney B Auerbac. GABAergic and glutamatergic afferents in the dorsal raphe nucleus mediate morphine-induced increases in serotonin efflux in the rat central nervous system. The Journal of pharmacology and experimental therapeutics. vol 303. issue 2. 2002-11-22. PMID:12388654. |
gabaergic and glutamatergic afferents in the dorsal raphe nucleus mediate morphine-induced increases in serotonin efflux in the rat central nervous system. |
2002-11-22 |
2023-08-12 |
rat |
| Rui Tao, Sidney B Auerbac. GABAergic and glutamatergic afferents in the dorsal raphe nucleus mediate morphine-induced increases in serotonin efflux in the rat central nervous system. The Journal of pharmacology and experimental therapeutics. vol 303. issue 2. 2002-11-22. PMID:12388654. |
these results suggest that morphine acts on gabaergic and glutamatergic afferents to indirectly influence the activity of 5-ht neurons in the drn. |
2002-11-22 |
2023-08-12 |
rat |
| Rongjian Liu, Yuqiang Ding, George K Aghajania. Neurokinins activate local glutamatergic inputs to serotonergic neurons of the dorsal raphe nucleus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 27. issue 3. 2002-11-15. PMID:12225691. |
we conclude that neurokinins, via distinct nk(1) and nk(3) receptors, could promote 5-ht transmission, at least in part, by exciting a local population of glutamatergic inputs to 5-ht neurons in the drn. |
2002-11-15 |
2023-08-12 |
rat |
| Xiang Cai, Zhenglin Gu, Ping Zhong, Yong Ren, Zhen Ya. Serotonin 5-HT1A receptors regulate AMPA receptor channels through inhibiting Ca2+/calmodulin-dependent kinase II in prefrontal cortical pyramidal neurons. The Journal of biological chemistry. vol 277. issue 39. 2002-11-13. PMID:12149253. |
we concluded that serotonin, by activating 5-ht(1a) receptors, suppress glutamatergic signaling through the inhibition of camkii, which is achieved by the inhibition of pka and ensuing activation of pp1. |
2002-11-13 |
2023-08-12 |
mouse |
| R K Kurup, R Nair, P A Kuru. Hypothalamic digoxin mediated model for oncogenesis. Journal of experimental & clinical cancer research : CR. vol 20. issue 4. 2002-09-06. PMID:11876554. |
digoxin induced tryptophan/tyrosine transport defect can alter neurotransmitter patterns with increased serotonin, quinolinic acid, nicotine & glutamatergic transmission and reduced dopamine, morphine and noradrenaline levels leading to oncogenesis. |
2002-09-06 |
2023-08-12 |
Not clear |
| Alfredo Menese. Tianeptine: 5-HT uptake sites and 5-HT(1-7) receptors modulate memory formation in an autoshaping Pavlovian/instrumental task. Neuroscience and biobehavioral reviews. vol 26. issue 3. 2002-07-30. PMID:12034133. |
tianeptine also normalized an impaired memory elicited by scopolamine (an antimuscarinic) or dizocilpine (non-competitive glutamatergic antagonist), while partially reversed that induced by tfmpp (5-ht(1b/1d/2a-2c/7) agonist/antagonist). |
2002-07-30 |
2023-08-12 |
Not clear |
| G J Blatt, C M Fitzgerald, J T Guptill, A B Booker, T L Kemper, M L Bauma. Density and distribution of hippocampal neurotransmitter receptors in autism: an autoradiographic study. Journal of autism and developmental disorders. vol 31. issue 6. 2002-07-16. PMID:11814263. |
based on these observations in the hippocampus, a series of quantitative receptor autoradiographic studies were undertaken to determine the density and distribution of eight types of neurotransmitter receptors from four neurotransmitter systems (gabaergic, serotoninergic [5-ht], cholinergic, and glutamatergic). |
2002-07-16 |
2023-08-12 |
Not clear |
| Karl-Erik Andersso. Treatment of the overactive bladder: possible central nervous system drug targets. Urology. vol 59. issue 5 Suppl 1. 2002-05-29. PMID:12007518. |
drugs affecting gamma-aminobutyric acid, opioid, serotonin, noradrenaline, dopamine, or glutamatergic receptors and mechanisms are known to influence micturition, and potentially such drugs could be developed for clinical use. |
2002-05-29 |
2023-08-12 |
Not clear |
| Guo-Du Wang, Min Zhu. Synergistic enhancement of glutamate-mediated responses by serotonin and forskolin in adult mouse spinal dorsal horn neurons. Journal of neurophysiology. vol 87. issue 2. 2002-03-26. PMID:11826042. |
the synergistic recruitment of functional ampa responses by 5-ht and forskolin provides a new cellular mechanism for glutamatergic synapses in mammalian spinal cord. |
2002-03-26 |
2023-08-12 |
mouse |
| A Siniscalchi, D Rodi, S Cavallini, S Marino, L Beani, C Bianch. Effects of cholecystokinin tetrapeptide (CCK(4)) and anxiolytic drugs on the electrically evoked [(3)H]5-hydroxytryptamine outflow from rat cortical slices. Brain research. vol 922. issue 1. 2002-02-19. PMID:11730707. |
thus, anxiolytic drugs with different receptor targets can reduce 5-ht outflow by dampening the glutamatergic signal, and in turn, the secretory process of the serotonergic nerve ending. |
2002-02-19 |
2023-08-12 |
rat |
| Terri L Whitworth, Laura C Herndon, Michael W Quic. Psychostimulants differentially regulate serotonin transporter expression in thalamocortical neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 1. 2002-02-04. PMID:11756522. |
5-ht transporters (serts) are transiently expressed in thalamocortical neurons during development, permitting these glutamatergic neurons to co-release 5-ht as a "borrowed" transmitter. |
2002-02-04 |
2023-08-12 |
rat |
| R Martín-Ruiz, M V Puig, P Celada, D A Shapiro, B L Roth, G Mengod, F Artiga. Control of serotonergic function in medial prefrontal cortex by serotonin-2A receptors through a glutamate-dependent mechanism. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 24. 2002-01-23. PMID:11739593. |
thus, doi reduces the activity of ascending 5-ht neurons through a dr-based action and enhances serotonergic and glutamatergic transmission in mpfc through 5-ht(2a) and ampa receptors. |
2002-01-23 |
2023-08-12 |
Not clear |
| M Shirane, K Nakamur. Aniracetam enhances cortical dopamine and serotonin release via cholinergic and glutamatergic mechanisms in SHRSP. Brain research. vol 916. issue 1-2. 2002-01-14. PMID:11597608. |
aniracetam enhances cortical dopamine and serotonin release via cholinergic and glutamatergic mechanisms in shrsp. |
2002-01-14 |
2023-08-12 |
rat |
| S T Szabo, P Blie. Serotonin (1A) receptor ligands act on norepinephrine neuron firing through excitatory amino acid and GABA(A) receptors: a microiontophoretic study in the rat locus coeruleus. Synapse (New York, N.Y.). vol 42. issue 4. 2002-01-10. PMID:11746719. |
these results suggest that way 100,635 mainly attenuates ne neuron firing by blocking inhibitory 5-ht(1a) receptors on glutamatergic neurons, thereby enhancing glutamate release and activating excitatory amino acid receptors, possibly of the kainate subtype, on 5-ht terminals. |
2002-01-10 |
2023-08-12 |
rat |
| M Marcoli, C Rosu, A Bonfanti, M Raiteri, G Maur. Inhibitory presynaptic 5-hydroxytryptamine(2A) receptors regulate evoked glutamate release from rat cerebellar mossy fibers. The Journal of pharmacology and experimental therapeutics. vol 299. issue 3. 2001-12-20. PMID:11714900. |
we studied the pharmacological characterization of the 5-hydroxytryptamine(2) (5-ht(2)) heteroreceptor located on glutamatergic cerebellar mossy fiber nerve terminals. |
2001-12-20 |
2023-08-12 |
rat |
| G J Marek, R A Wright, J C Gewirtz, D D Schoep. A major role for thalamocortical afferents in serotonergic hallucinogen receptor function in the rat neocortex. Neuroscience. vol 105. issue 2. 2001-12-07. PMID:11672605. |
the purpose of the present study was to determine the source of subcortical glutamatergic afferents, which would project widely throughout the anterior-posterior axis of the rat brain to the apical dendrites of layer v pyramidal cells of the medial prefrontal cortex, from which serotonin induces transmitter release via activation of 5-ht(2a) receptors. |
2001-12-07 |
2023-08-12 |
rat |
| E Svensson, S Grillner, D Parke. Gating and braking of short- and long-term modulatory effects by interactions between colocalized neuromodulators. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 16. 2001-08-30. PMID:11487621. |
5-ht also blocked the presynaptic facilitation of glutamatergic synaptic transmission by substance p. the presynaptic, but not postsynaptic, effect of 5-ht was reduced by the protein phosphatase 2b inhibitor cypermethrin. |
2001-08-30 |
2023-08-12 |
Not clear |
| E Svensson, S Grillner, D Parke. Gating and braking of short- and long-term modulatory effects by interactions between colocalized neuromodulators. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 16. 2001-08-30. PMID:11487621. |
dopamine did not directly modulate the effects of substance p. however, it reduced the presynaptic interactive effect of 5-ht and thus gated the presynaptic potentiation of glutamatergic inputs by substance p. however, the substance p-mediated potentiation of nmda responses was not gated by dopamine, and thus the long-term network modulation was not induced. |
2001-08-30 |
2023-08-12 |
Not clear |
| B Di Cara, N Dusticier, C Forni, J C Lievens, A Daszut. Serotonin depletion produces long lasting increase in striatal glutamatergic transmission. Journal of neurochemistry. vol 78. issue 2. 2001-08-23. PMID:11461959. |
serotonin depletion produces long lasting increase in striatal glutamatergic transmission. |
2001-08-23 |
2023-08-12 |
rat |