| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Motohiro Okada, Ryusuke Matsumoto, Yoshimasa Yamamoto, Kouji Fukuyam. Effects of Subchronic Administrations of Vortioxetine, Lurasidone, and Escitalopram on Thalamocortical Glutamatergic Transmission Associated with Serotonin 5-HT7 Receptor. International journal of molecular sciences. vol 22. issue 3. 2021-09-07. PMID:33572981. |
effects of subchronic administrations of vortioxetine, lurasidone, and escitalopram on thalamocortical glutamatergic transmission associated with serotonin 5-ht7 receptor. |
2021-09-07 |
2023-08-13 |
Not clear |
| Saida Oubraim, Ruixiang Wang, Kathryn A Hausknecht, Roh-Yu Shen, Samir Haj-Dahman. Tonic Endocannabinoid Signaling Gates Synaptic Plasticity in Dorsal Raphe Nucleus Serotonin Neurons Through Peroxisome Proliferator-Activated Receptors. Frontiers in pharmacology. vol 12. 2021-07-16. PMID:34262460. |
in this study, we show that both 2-ag and aea are constitutively released in the dorsal raphe nucleus (drn), where they exert tonic control of glutamatergic synaptic transmission onto serotonin (5-ht) neurons. |
2021-07-16 |
2023-08-13 |
Not clear |
| Anes Ju, Beatriz Fernandez-Arroyo, Yifan Wu, Débora Jacky, Anna Beyele. Expression of serotonin 1A and 2A receptors in molecular- and projection-defined neurons of the mouse insular cortex. Molecular brain. vol 13. issue 1. 2021-07-08. PMID:32594910. |
these observations suggest that most glutamatergic neurons can respond to 5-ht through 5-ht1a or 5-ht2a in the insula, and that 5-ht directly affects a limited number of gabaergic neurons. |
2021-07-08 |
2023-08-13 |
mouse |
| Joanna Sowa, Grzegorz Hes. Prenatal stress-related alterations in synaptic transmission and 5-HT The European journal of neuroscience. vol 52. issue 5. 2021-06-21. PMID:32402149. |
the present study was aimed at finding whether prenatal stress induces modifications in the glutamatergic and gabaergic inputs to drn projection cells and whether it affects drn 5-ht |
2021-06-21 |
2023-08-13 |
rat |
| Amina Benhadda, Emily Quentin, Imane Moutkine, Benjamin Chanrion, Marion Russeau, Philippe Marin, Sabine Levi, Luc Maroteau. Serotonin 2B Receptor by Interacting with NMDA Receptor and CIPP Protein Complex May Control Structural Plasticity at Glutamatergic Synapses. ACS chemical neuroscience. vol 12. issue 7. 2021-06-18. PMID:33739808. |
serotonin 2b receptor by interacting with nmda receptor and cipp protein complex may control structural plasticity at glutamatergic synapses. |
2021-06-18 |
2023-08-13 |
Not clear |
| Eun-Young Kim, Jeong-Eun Choi, Mijin Kim, Jisu Hong, Yongsoon Par. N-3 PUFA Have Antidepressant-like Effects Via Improvement of the HPA-Axis and Neurotransmission in Rats Exposed to Combined Stress. Molecular neurobiology. vol 57. issue 9. 2021-06-03. PMID:32613466. |
n-3 pufa also modulated brain phospholipid fatty acid concentration, thus reducing inflammatory cytokines; improved the serotonergic pathway, thus increasing the expression of the brain-derived neurotrophic factor (bdnf), camp response element-binding protein (creb), serotonin-1a receptor, and serum levels of serotonin; but did not affect glutamatergic neurotransmission. |
2021-06-03 |
2023-08-13 |
rat |
| Hugo R Arias, Katarzyna M Targowska-Duda, Jesús García-Colunga, Marcelo O Ortell. Is the Antidepressant Activity of Selective Serotonin Reuptake Inhibitors Mediated by Nicotinic Acetylcholine Receptors? Molecules (Basel, Switzerland). vol 26. issue 8. 2021-05-13. PMID:33917953. |
studies on dorsal raphe nucleus serotoninergic neurons support the concept that ssri-induced nachr inhibition decreases the glutamatergic hyperstimulation observed in stress conditions, which compensates the excessive 5-ht overflow in these neurons and, consequently, ameliorates depression symptoms. |
2021-05-13 |
2023-08-13 |
Not clear |
| Mohammad Jafferany, Ruzanna Mkhoyan, Gulhima Arora, Roxanna Sadoughifar, Etleva Jorgaqi, Mohamad Goldus. Treatment of skin picking disorder: Interdisciplinary role of dermatologist and psychiatrist. Dermatologic therapy. vol 33. issue 6. 2021-04-26. PMID:32542859. |
various pharmacological agents particularly selective serotonin reuptake inhibitors and glutamatergic agents have been tried with variable success. |
2021-04-26 |
2023-08-13 |
Not clear |
| Lucia Caffino, Francesca Mottarlini, Boyd Van Reijmersdal, Francesca Telese, Michel M M Verheij, Fabio Fumagalli, Judith R Homber. The role of the serotonin transporter in prefrontal cortex glutamatergic signaling following short- and long-access cocaine self-administration. Addiction biology. vol 26. issue 2. 2021-03-26. PMID:32187792. |
the role of the serotonin transporter in prefrontal cortex glutamatergic signaling following short- and long-access cocaine self-administration. |
2021-03-26 |
2023-08-13 |
Not clear |
| Lucia Caffino, Michel M M Verheij, Lin Que, Chao Guo, Judith R Homberg, Fabio Fumagall. Increased cocaine self-administration in rats lacking the serotonin transporter: a role for glutamatergic signaling in the habenula. Addiction biology. vol 24. issue 6. 2020-10-28. PMID:30144237. |
increased cocaine self-administration in rats lacking the serotonin transporter: a role for glutamatergic signaling in the habenula. |
2020-10-28 |
2023-08-13 |
rat |
| Lucia Caffino, Michel M M Verheij, Lin Que, Chao Guo, Judith R Homberg, Fabio Fumagall. Increased cocaine self-administration in rats lacking the serotonin transporter: a role for glutamatergic signaling in the habenula. Addiction biology. vol 24. issue 6. 2020-10-28. PMID:30144237. |
evidence exists that 5-ht influences hb glutamatergic transmission. |
2020-10-28 |
2023-08-13 |
rat |
| Xiao-Cui Yuan, Bing Zhu, Xiang-Hong Jing, Li-Ze Xiong, Cai-Hua Wu, Fang Gao, Hong-Ping Li, Hong-Chun Xiang, He Zhu, Bin Zhou, Wei He, Chuan-You Lin, Hui-Lin Pan, Qiang Wang, Man L. Electroacupuncture Potentiates Cannabinoid Receptor-Mediated Descending Inhibitory Control in a Mouse Model of Knee Osteoarthritis. Frontiers in molecular neuroscience. vol 11. 2020-10-01. PMID:29681797. |
in addition, cb1 receptors on gabaergic but not glutamatergic neurons are involved in the ea effect on dnic function and descending inhibitory control of 5-ht in the medulla, thus inhibiting chronic pain. |
2020-10-01 |
2023-08-13 |
mouse |
| Jate Bernard, Abigail Greenhalgh, Oscar Istas, Nicole T Marguerite, Robin L Coope. The Effect of Bacterial Endotoxin LPS on Serotonergic Modulation of Glutamatergic Synaptic Transmission. Biology. vol 9. issue 8. 2020-09-28. PMID:32781679. |
at the model glutamatergic synapse of the crayfish neuromuscular junction (nmj), 5-ht primarily acts through a 5-ht2a receptor subtype to enhance transmission to the motor neurons. |
2020-09-28 |
2023-08-13 |
Not clear |
| Paria Baharikhoob, Nathan J Koll. Microglial Dysregulation and Suicidality: A Stress-Diathesis Perspective. Frontiers in psychiatry. vol 11. 2020-09-28. PMID:32848946. |
the studies also suggested several pathological mechanisms leading to suicidal behavior that may involve microglial dysregulation, namely (1) enhanced metabolism of tryptophan to quinolinic acid through the kynurenine pathway and associated serotonin depletion; (2) increased quinolinic acid leading to excessive n-methyl-d-aspartate-signaling, resulting in potential disruption of the blood brain barrier; (3) increased quinolinic acid resulting in higher neurotoxicity, and; (4) elevated interleukin 6 contributing to loss of inhibition of glutamatergic neurons, causing heightened glutamate release and excitotoxicity. |
2020-09-28 |
2023-08-13 |
human |
| Motohiro Okada, Kouji Fukuyama, Yuto Ued. Lurasidone inhibits NMDA receptor antagonist-induced functional abnormality of thalamocortical glutamatergic transmission via 5-HT British journal of pharmacology. vol 176. issue 20. 2020-09-22. PMID:31347694. |
lurasidone inhibits nmda receptor antagonist-induced functional abnormality of thalamocortical glutamatergic transmission via 5-ht lurasidone is an atypical mood-stabilizing antipsychotic with a unique receptor-binding profile, including 5-ht |
2020-09-22 |
2023-08-13 |
Not clear |
| Masanori Dantsuji, Shiro Nakamura, Kiyomi Nakayama, Ayako Mochizuki, Sook Kyung Park, Yong Chul Bae, Masahiko Ozeki, Tomio Inou. 5-HT The Journal of physiology. vol 597. issue 9. 2020-07-14. PMID:30919966. |
in this study, we focused on how 5-ht enhances postsynaptic glutamatergic responses in the dendrites of the jaw-closing motoneurons. |
2020-07-14 |
2023-08-13 |
Not clear |
| Masanori Dantsuji, Shiro Nakamura, Kiyomi Nakayama, Ayako Mochizuki, Sook Kyung Park, Yong Chul Bae, Masahiko Ozeki, Tomio Inou. 5-HT The Journal of physiology. vol 597. issue 9. 2020-07-14. PMID:30919966. |
we demonstrate that 5-ht augments glutamatergic signalling by enhancing the function of the glun2a-containing nmda receptor (nmdar) through the activation of 5-ht |
2020-07-14 |
2023-08-13 |
Not clear |
| M A Al Kahtan. Effect of both selenium and biosynthesized nanoselenium particles on cadmium-induced neurotoxicity in albino rats. Human & experimental toxicology. vol 39. issue 2. 2020-06-02. PMID:31619074. |
it also affects cholinergic, glutamatergic, gamma-aminobutyric acid (gabaergic), dopamine, serotonin and acetylcholine neurotransmitters in brain tissue. |
2020-06-02 |
2023-08-13 |
rat |
| Coralie Berthoux, Alexander Barre, Joël Bockaert, Philippe Marin, Carine Bécame. Sustained Activation of Postsynaptic 5-HT2A Receptors Gates Plasticity at Prefrontal Cortex Synapses. Cerebral cortex (New York, N.Y. : 1991). vol 29. issue 4. 2020-05-22. PMID:29917056. |
among the 5-ht receptors abundantly expressed in pfc, 5-ht2a receptors located in dendrites of layer v pyramidal neurons control neuronal excitability and mediate the psychotropic effects of psychedelic hallucinogens, but their impact on glutamatergic transmission and synaptic plasticity remains poorly characterized. |
2020-05-22 |
2023-08-13 |
mouse |
| Thu Ha Pham, Alain M Gardie. Fast-acting antidepressant activity of ketamine: highlights on brain serotonin, glutamate, and GABA neurotransmission in preclinical studies. Pharmacology & therapeutics. vol 199. 2020-04-27. PMID:30851296. |
however, these mpfc effects are not restricted to glutamatergic pyramidal cells, but extend to other neurotransmitters (gaba, serotonin), glial cells, and brain circuits (mpfc/dorsal raphe nucleus-drn). |
2020-04-27 |
2023-08-13 |
Not clear |