| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Samir Haj-Dahmane, Jean Claude Béïque, Roh-Yu She. GluA2-Lacking AMPA Receptors and Nitric Oxide Signaling Gate Spike-Timing-Dependent Potentiation of Glutamate Synapses in the Dorsal Raphe Nucleus. eNeuro. vol 4. issue 3. 2018-03-28. PMID:28580416. |
the dorsal raphe nucleus (drn) receives glutamatergic inputs from numerous brain areas that control the function of drn serotonin (5-ht) neurons. |
2018-03-28 |
2023-08-13 |
rat |
| Paula Sm Yamashita, Ailton Spiacci, James E Hassel, Christopher A Lowry, Helio Zangross. Disinhibition of the rat prelimbic cortex promotes serotonergic activation of the dorsal raphe nucleus and panicolytic-like behavioral effects. Journal of psychopharmacology (Oxford, England). vol 31. issue 6. 2018-03-22. PMID:28071216. |
anatomical studies indicate that the prelimbic (pl) cortex sends dense glutamatergic projections to the dr, leading to stimulation or inhibition of serotonin release in structures innervated by the dr. |
2018-03-22 |
2023-08-13 |
rat |
| Chai K Lim, Musthafa M Essa, Roberta de Paula Martins, David B Lovejoy, Ayse A Bilgin, Mostafa I Waly, Yahya M Al-Farsi, Marwan Al-Sharbati, Mohammed A Al-Shaffae, Gilles J Guillemi. Altered kynurenine pathway metabolism in autism: Implication for immune-induced glutamatergic activity. Autism research : official journal of the International Society for Autism Research. vol 9. issue 6. 2018-01-29. PMID:26497015. |
as the kynurenine pathway (kp) of tryptophan degradation is activated in neuroinflammatory states, we hypothesized that there may be a link between inflammation in asd and enhanced kp activation resulting in reduced serotonin synthesis from tryptophan and production of kp metabolites capable of modulating glutamatergic activity. |
2018-01-29 |
2023-08-13 |
human |
| Rachel Asselot, Emmanuelle Simon-O'Brien, Sophie Lebourgeois, Gérald Nee, Virgile Delaunay, Pascal Duchatelle, Valentine Bouet, François Dauphi. Time-dependent impact of glutamatergic modulators on the promnesiant effect of 5-HT Pharmacological research. vol 118. 2018-01-10. PMID:27373846. |
time-dependent impact of glutamatergic modulators on the promnesiant effect of 5-ht selective antagonists at serotonin 5-ht |
2018-01-10 |
2023-08-13 |
Not clear |
| Xiaoning Chen, Emilie I Petit, Kostantin Dobrenis, Ji Ying Sz. Spatiotemporal SERT expression in cortical map development. Neurochemistry international. vol 98. 2018-01-08. PMID:27282696. |
here, we characterize temporal- and spatial-defined expression of serotonin (5-ht) transporter (sert) in glutamatergic neurons during sensory map development in mice. |
2018-01-08 |
2023-08-13 |
mouse |
| Alberto Rubio-Casillas, Alonso Fernández-Guast. The dose makes the poison: from glutamate-mediated neurogenesis to neuronal atrophy and depression. Reviews in the neurosciences. vol 27. issue 6. 2018-01-02. PMID:27096778. |
the dysregulation of the glutamatergic transmission in depression could be underlined by several factors including a decreased inhibition (γ-aminobutyric acid or serotonin) or an increased excitation (primarily within the glutamatergic system). |
2018-01-02 |
2023-08-13 |
Not clear |
| Lara Eid, Martin Paren. Chemical anatomy of pallidal afferents in primates. Brain structure & function. vol 221. issue 9. 2017-10-13. PMID:27028222. |
altogether, these findings reveal that the brainstem 5-ht, ach and da pallidal afferents act in concert with the more robust gabaergic inhibitory striatopallidal and glutamatergic excitatory subthalamopallidal inputs. |
2017-10-13 |
2023-08-13 |
Not clear |
| Andor Domonkos, Litsa Nikitidou Ledri, Tamás Laszlovszky, Csaba Cserép, Zsolt Borhegyi, Edit Papp, Gábor Nyiri, Tamás F Freund, Viktor Varg. Divergent in vivo activity of non-serotonergic and serotonergic VGluT3-neurones in the median raphe region. The Journal of physiology. vol 594. issue 13. 2017-08-14. PMID:27028801. |
we provide the first description of the in vivo, brain state-dependent firing properties of median raphe glutamatergic neurones identified by immunopositivity for the vesicular glutamate transporter type 3 (vglut3) and serotonin (5-ht). |
2017-08-14 |
2023-08-13 |
Not clear |
| Jonathan Savit. Role of Kynurenine Metabolism Pathway Activation in Major Depressive Disorders. Current topics in behavioral neurosciences. vol 31. 2017-06-20. PMID:27221627. |
initially, activation of the kynurenine pathway was believed to precipitate depressive symptoms by depleting brain serotonin, however, the weight of the evidence now suggests that an imbalance between neurotoxic and neuroprotective metabolites may be the principal driver of depression; conceivably via its effects on glutamatergic neurotransmission. |
2017-06-20 |
2023-08-13 |
Not clear |
| Yuko Yoshimura, Chihiro Ishikawa, Haruki Kasegai, Tomoyuki Masuda, Masaaki Yoshikawa, Takashi Shig. Roles of 5-HT Neuroscience research. vol 115. 2017-04-11. PMID:27702575. |
roles of 5-ht the possible interactions between serotonergic and glutamatergic systems during neural development and under the pathogenesis of depression remain unclear. |
2017-04-11 |
2023-08-13 |
Not clear |
| Kristian Gaarn du Jardin, Heidi Kaastrup Müller, Connie Sanchez, Gregers Wegener, Betina Elfvin. A single dose of vortioxetine, but not ketamine or fluoxetine, increases plasticity-related gene expression in the rat frontal cortex. European journal of pharmacology. vol 786. 2017-03-10. PMID:27235984. |
here, we investigate the effects of ketamine and vortioxetine on gene expression related to serotonergic and glutamatergic neurotransmission as well as neuroplasticity and compare them to those of the selective serotonin reuptake inhibitor fluoxetine. |
2017-03-10 |
2023-08-13 |
rat |
| Guiqin Xie, Wanhong Zuo, Liangzhi Wu, Wenting Li, Wei Wu, Alex Bekker, Jiang-Hong Y. Serotonin modulates glutamatergic transmission to neurons in the lateral habenula. Scientific reports. vol 6. 2017-02-17. PMID:27033153. |
serotonin modulates glutamatergic transmission to neurons in the lateral habenula. |
2017-02-17 |
2023-08-13 |
rat |
| Guiqin Xie, Wanhong Zuo, Liangzhi Wu, Wenting Li, Wei Wu, Alex Bekker, Jiang-Hong Y. Serotonin modulates glutamatergic transmission to neurons in the lateral habenula. Scientific reports. vol 6. 2017-02-17. PMID:27033153. |
we compared serotonin's effects on glutamatergic transmission across the lhb in rat brains. |
2017-02-17 |
2023-08-13 |
rat |
| Guiqin Xie, Wanhong Zuo, Liangzhi Wu, Wenting Li, Wei Wu, Alex Bekker, Jiang-Hong Y. Serotonin modulates glutamatergic transmission to neurons in the lateral habenula. Scientific reports. vol 6. 2017-02-17. PMID:27033153. |
serotonin bi-directionally and differentially modulated glutamatergic transmission. |
2017-02-17 |
2023-08-13 |
rat |
| Guiqin Xie, Wanhong Zuo, Liangzhi Wu, Wenting Li, Wei Wu, Alex Bekker, Jiang-Hong Y. Serotonin modulates glutamatergic transmission to neurons in the lateral habenula. Scientific reports. vol 6. 2017-02-17. PMID:27033153. |
serotonin inhibited glutamatergic transmission in higher percentage of lhbl neurons but potentiated in higher percentage of lhbm neurons. |
2017-02-17 |
2023-08-13 |
rat |
| Guiqin Xie, Wanhong Zuo, Liangzhi Wu, Wenting Li, Wei Wu, Alex Bekker, Jiang-Hong Y. Serotonin modulates glutamatergic transmission to neurons in the lateral habenula. Scientific reports. vol 6. 2017-02-17. PMID:27033153. |
the serotonin reuptake blocker, and the type 2 and 3 receptor agonists facilitated glutamatergic transmission in both lhbl and lhbm neurons. |
2017-02-17 |
2023-08-13 |
rat |
| Josipa Vlainić Vlainić, Jelena Šuran, Toni Vlainić, Antonella Letizia Vukore. Probiotics as an Adjuvant Therapy in Major Depressive Disorder. Current neuropharmacology. vol 14. issue 8. 2017-01-17. PMID:27226112. |
it has been shown that dysregulation of hypothalamus-pituitary-adrenal (hpa) axis, imbalance between anti- and pro-inflammatory cytokines, depletion of neurotransmitters (serotonin, norepinephrine and/or dopamine) in the central nervous system, altered glutamatergic and gabaergic transmission have an important role in the pathogenesis of depression. |
2017-01-17 |
2023-08-13 |
Not clear |
| Helene M Savignac, Yvonne Couch, Michael Stratford, David M Bannerman, George Tzortzis, Daniel C Anthony, Philip W J Burne. Prebiotic administration normalizes lipopolysaccharide (LPS)-induced anxiety and cortical 5-HT2A receptor and IL1-β levels in male mice. Brain, behavior, and immunity. vol 52. 2016-12-13. PMID:26476141. |
cytokine expression, and key components of the serotonergic (5-hydroxytryptamine, 5-ht) and glutamatergic system were evaluated in the frontal cortex to determine the impact of bgos administration at a molecular level. |
2016-12-13 |
2023-08-13 |
mouse |
| Sean D Geddes, Saleha Assadzada, David Lemelin, Alexandra Sokolovski, Richard Bergeron, Samir Haj-Dahmane, Jean-Claude Béïqu. Target-specific modulation of the descending prefrontal cortex inputs to the dorsal raphe nucleus by cannabinoids. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 19. 2016-12-13. PMID:27114535. |
here, we found that the mpfc provides a direct monosynaptic, glutamatergic drive to both drn 5-ht and gaba neurons and that this architecture was conducive to a robust feed-forward inhibition. |
2016-12-13 |
2023-08-13 |
Not clear |
| Eric J Nordstrom, Katie C Bittner, Michael J McGrath, Clinton R Parks, Frank H Burto. "Hyperglutamatergic cortico-striato-thalamo-cortical circuit" breaker drugs alleviate tics in a transgenic circuit model of Tourette׳s syndrome. Brain research. vol 1629. 2016-09-22. PMID:26453289. |
here we have examined whether these mice׳s tics are countered by drugs that "break" sequential elements of their hyperactive cortical/amygdalar glutamatergic and efferent striatal circuit: anti-serotonoceptive and anti-noradrenoceptive corticostriatal glutamate output blockers (the serotonin 5-ht2a,c receptor antagonist ritanserin and the ne alpha-1 receptor antagonist prazosin); agmatinergic striatothalamic gaba output blockers (the presynaptic agmatine/imidazoline i1 receptor agonist moxonidine); and nigrostriatal dopamine output blockers (the presynaptic d2 receptor agonist bromocriptine). |
2016-09-22 |
2023-08-13 |
mouse |