| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| In-Sun Choi, Jin-Hwa Cho, Il-Sung Jan. 5-Hydroxytryptamine 1A receptors inhibit glutamate release in rat medullary dorsal horn neurons. Neuroreport. vol 24. issue 8. 2013-11-14. PMID:23629688. |
we examined 5-hydroxytryptamine 1a (5-ht1a) receptor-mediated modulation of glutamatergic transmission in rat medullary dorsal horn neurons using a conventional whole-cell patch clamp technique. |
2013-11-14 |
2023-08-12 |
rat |
| In-Sun Choi, Jin-Hwa Cho, Il-Sung Jan. 5-Hydroxytryptamine 1A receptors inhibit glutamate release in rat medullary dorsal horn neurons. Neuroreport. vol 24. issue 8. 2013-11-14. PMID:23629688. |
5-ht reversibly and concentration dependently decreased the amplitude of glutamatergic excitatory postsynaptic currents and increased the paired-pulse ratio, indicating that 5-ht acts presynaptically to reduce glutamate release from primary afferents. |
2013-11-14 |
2023-08-12 |
rat |
| M Häring, M Grieb, K Monory, B Lutz, F A Moreir. Cannabinoid CB₁ receptor in the modulation of stress coping behavior in mice: the role of serotonin and different forebrain neuronal subpopulations. Neuropharmacology. vol 65. 2013-10-17. PMID:23000076. |
the aim of this work was to investigate the involvement of serotonin (5-ht) and catecholamines, as well as the role of glutamatergic and gabaergic cannabinoid type 1 (cb(1)) receptor, in responses to the antidepressant-like doses of the cb(1) receptor agonist Δ(9)-tetrahydrocannabinol (thc) and the antagonist rimonabant in the forced swim test (fst). |
2013-10-17 |
2023-08-12 |
mouse |
| Caitlin E McOmish, Alena Lira, James B Hanks, Jay A Gingric. Clozapine-induced locomotor suppression is mediated by 5-HT2A receptors in the forebrain. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 13. 2013-08-26. PMID:22871913. |
restoration of 5-ht(2a) expression to cortical glutamatergic neurons re-instated the locomotor-suppressing effects of clozapine in the open field. |
2013-08-26 |
2023-08-12 |
mouse |
| Chiung-Chun Huang, Che-Ming Yeh, Mei-Ying Wu, Kuei-Sen Hs. A single in vivo cocaine administration impairs 5-HT(1B) receptor-induced long-term depression in the nucleus accumbens. Journal of neurochemistry. vol 125. issue 6. 2013-08-06. PMID:23452061. |
here, we demonstrate that brief application of 5-ht or 5-ht1b receptor agonist cp 93129 induced a long-term depression (ltd) of glutamatergic transmission in nac neurons. |
2013-08-06 |
2023-08-12 |
mouse |
| Krzysztof Tokarski, Bartosz Bobula, Małgorzata Grzegorzewska-Hiczwa, Magdalena Kusek, Grzegorz Hes. Stress- and antidepressant treatment-induced modifications of 5-HT₇ receptor functions in the rat brain. Pharmacological reports : PR. vol 64. issue 6. 2013-07-16. PMID:23406741. |
these studies demonstrated that 5-ht(7) receptors play an important role in the modulation of the activity of the hippocampal network by regulating the excitability of pyramidal cells of the ca1 area, as well as via their effect on gaba and glutamatergic transmission. |
2013-07-16 |
2023-08-12 |
rat |
| Krzysztof Tokarski, Bartosz Bobula, Małgorzata Grzegorzewska-Hiczwa, Magdalena Kusek, Grzegorz Hes. Stress- and antidepressant treatment-induced modifications of 5-HT₇ receptor functions in the rat brain. Pharmacological reports : PR. vol 64. issue 6. 2013-07-16. PMID:23406741. |
it has also been shown that the changes in glutamatergic transmission and the impairment of long-term synaptic plasticity in the frontal cortex of animals subjected to repeated restraint stress are reversed by the blockade of 5-ht(7) receptors. |
2013-07-16 |
2023-08-12 |
rat |
| José Julio Rodríguez, Harun N Noristani, Alexei Verkhratsk. The serotonergic system in ageing and Alzheimer's disease. Progress in neurobiology. vol 99. issue 1. 2013-07-10. PMID:22766041. |
following the discovery and establishment of its role as a neurotransmitter, serotonin (5-ht), was found to be involved in a multitude of neurophysiological processes including mnesic function, through its dedicated pathways and interaction with cholinergic, glutamatergic, gabaergic and dopaminergic transmission systems. |
2013-07-10 |
2023-08-12 |
Not clear |
| S S Daftary, G Calderon, M Rio. Essential role of brain-derived neurotrophic factor in the regulation of serotonin transmission in the basolateral amygdala. Neuroscience. vol 224. 2013-06-17. PMID:22917617. |
notably, whole cell recordings in bla pyramidal cells uncovered significant alterations in 5-ht(2)-mediated regulation of gabaergic and glutamatergic transmission in bdnf(2l/2lck-cre) mutant mice that result in a hyperexcitable circuit. |
2013-06-17 |
2023-08-12 |
mouse |
| Shengyuan Ding, Li Li, Fu-Ming Zho. Presynaptic serotonergic gating of the subthalamonigral glutamatergic projection. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 11. 2013-05-06. PMID:23486958. |
the snr also receives an intense serotonin (5-ht) innervation, raising the possibility that 5-ht may regulate the stn→snr glutamatergic transmission and the consequent stn-triggered spike firing in snr neurons. |
2013-05-06 |
2023-08-12 |
Not clear |
| Jue Wang, Roh-Yu Shen, Samir Haj-Dahman. Endocannabinoids mediate the glucocorticoid-induced inhibition of excitatory synaptic transmission to dorsal raphe serotonin neurons. The Journal of physiology. vol 590. issue 22. 2013-05-01. PMID:22946098. |
we found that corticosterone or the synthetic glucocorticoid agonist dexamethasone rapidly suppressed glutamatergic synaptic transmission to dr 5-ht neurons by inhibiting glutamate release in the dr. |
2013-05-01 |
2023-08-12 |
Not clear |
| Lena Wischhof, Helena E A Aho, Michael Koc. DOI-induced deficits in prepulse inhibition in Wistar rats are reversed by mGlu2/3 receptor stimulation. Pharmacology, biochemistry, and behavior. vol 102. issue 1. 2013-03-14. PMID:22469865. |
interactions of the serotonin (5-hydroxytryptamine, 5-ht) and glutamatergic systems, especially via the 5-ht(2a) receptor subtype, have been implicated in the regulation of ppi. |
2013-03-14 |
2023-08-12 |
rat |
| Morteza Zendehdel, Majid Taati, Hosein Jonaidi, Elham Amin. The role of central 5-HT(2C) and NMDA receptors on LPS-induced feeding behavior in chickens. The journal of physiological sciences : JPS. vol 62. issue 5. 2013-01-18. PMID:22735975. |
in the following experiments, we used dl-ap5 before 5-ht (10 μg) and sb242084 before glutamate (300 nm) for evaluation of the interaction between 5-htergic and glutamatergic systems on food intake. |
2013-01-18 |
2023-08-12 |
Not clear |
| Gaynor A Smith, Ludivine S Breger, Emma L Lane, Stephen B Dunnet. Pharmacological modulation of amphetamine-induced dyskinesia in transplanted hemi-parkinsonian rats. Neuropharmacology. vol 63. issue 5. 2013-01-14. PMID:22722025. |
agents include: dopaminergic antagonists (d₁: cp94253; d₂: sch-22390; d₃: nafadotride), serotonergic agonists (5-ht(1a): 8-oh-dpat; 5-ht(1b): cp94253), opioid antagonist (μ: naloxone), cannabinoid agonist (cb₁: win55, 212-2), adrenergic antagonist (α₁ and α₂: yohimbine) and glutamatergic antagonists (nmda: amantadine and mk-801; mglur5: mtep; ampa: iem1460). |
2013-01-14 |
2023-08-12 |
rat |
| S Woods, N N Clarke, R Layfield, K C F Fon. 5-HT(6) receptor agonists and antagonists enhance learning and memory in a conditioned emotion response paradigm by modulation of cholinergic and glutamatergic mechanisms. British journal of pharmacology. vol 167. issue 2. 2013-01-07. PMID:22568655. |
5-ht(6) receptor agonists and antagonists enhance learning and memory in a conditioned emotion response paradigm by modulation of cholinergic and glutamatergic mechanisms. |
2013-01-07 |
2023-08-12 |
Not clear |
| Julieta Garduño, Luis Galindo-Charles, Javier Jiménez-Rodríguez, Elvira Galarraga, Dagoberto Tapia, Stefan Mihailescu, Salvador Hernandez-Lope. Presynaptic α4β2 nicotinic acetylcholine receptors increase glutamate release and serotonin neuron excitability in the dorsal raphe nucleus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 43. 2013-01-07. PMID:23100436. |
using whole-cell recording techniques, we investigated the effects of nicotine on the glutamatergic input to 5-ht drn neurons in rat midbrain slices. |
2013-01-07 |
2023-08-12 |
rat |
| Samira G Ferreira, Filipe M Teixeira, Pedro Garção, Paula Agostinho, Catherine Ledent, Luísa Cortes, Ken Mackie, Attila Köfalv. Presynaptic CB(1) cannabinoid receptors control frontocortical serotonin and glutamate release--species differences. Neurochemistry international. vol 61. issue 2. 2012-12-07. PMID:22609378. |
glutamatergic) and serotonin transporter- (i.e. |
2012-12-07 |
2023-08-12 |
mouse |
| A Mickle, P Kannampalli, M Bruckert, A Miranda, B Banerjee, J N Sengupt. Pronociceptive effect of 5-HT(1A) receptor agonist on visceral pain involves spinal N-methyl-D-aspartate (NMDA) receptor. Neuroscience. vol 219. 2012-11-20. PMID:22626644. |
these results indicate that the 5-ht(1a) receptor agonist dpat produces pronociceptive effects, primarily via the activation of presynaptic 5-ht(1a) receptors in gabaergic neuron to restrict gaba release and thereby disinhibits the excitatory glutamatergic neurons in the spinal cord. |
2012-11-20 |
2023-08-12 |
rat |
| R T Owe. Glutamatergic approaches in major depressive disorder: focus on ketamine, memantine and riluzole. Drugs of today (Barcelona, Spain : 1998). vol 48. issue 7. 2012-10-23. PMID:22844658. |
existing antidepressants have been shown to exert effects on various glutamatergic mechanisms, even if such agents are traditionally classified as working via other mechanisms, such as selective serotonin reuptake inhibitors. |
2012-10-23 |
2023-08-12 |
Not clear |
| Patrick M Fisher, Julie C Price, Carolyn C Meltzer, Eydie L Moses-Kolko, Carl Becker, Sarah L Berga, Ahmad R Harir. Medial prefrontal cortex serotonin 1A and 2A receptor binding interacts to predict threat-related amygdala reactivity. Biology of mood & anxiety disorders. vol 1. issue 1. 2012-10-02. PMID:22738071. |
the colocalization of 5-ht1a and 5-ht2a receptors on mpfc glutamatergic neurons suggests that their functional interactions may mediate 5-ht effects on this circuit through top-down regulation of amygdala reactivity. |
2012-10-02 |
2023-08-12 |
human |