| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E K Perr. Nerve growth factor and the basal forebrain cholinergic system: a link in the etiopathology of neurodegenerative dementias? Alzheimer disease and associated disorders. vol 4. issue 1. 1990-05-07. PMID:2180439. |
the discovery of a specific association between nerve growth factor (ngf) and basal forebrain cholinergic neurons (bfcns) marks the beginning of a new era of research into neurodegenerative diseases such as alzheimer disease (ad). |
1990-05-07 |
2023-08-11 |
human |
| J Ille. Neurolinguistic features of spontaneous language production dissociate three forms of neurodegenerative disease: Alzheimer's, Huntington's, and Parkinson's. Brain and language. vol 37. issue 4. 1989-12-22. PMID:2479447. |
neurolinguistic features of spontaneous language production dissociate three forms of neurodegenerative disease: alzheimer's, huntington's, and parkinson's. |
1989-12-22 |
2023-08-11 |
Not clear |
| R Cacabelos, A Yamatodani, H Niigawa, S Hariguchi, K Tada, T Nishimura, H Wada, L Brandeis, J Pearso. Brain histamine in Alzheimer's disease. Methods and findings in experimental and clinical pharmacology. vol 11. issue 5. 1989-09-05. PMID:2755282. |
the concentration of histamine (ha) has been determined by high-performance liquid chromatography (hplc) with fluorometric detection in 21 different regions of brains from patients with senile dementia of the alzheimer type (sdat) and subjects (cb) whose causes of death were not related to neuropsychiatric, neurological and/or neurodegenerative diseases. |
1989-09-05 |
2023-08-11 |
human |
| G W Roberts, R Lofthouse, D Allsop, M Landon, M Kidd, S B Prusiner, T J Cro. CNS amyloid proteins in neurodegenerative diseases. Neurology. vol 38. issue 10. 1988-10-27. PMID:2901696. |
two amyloidogenic proteins have been isolated from the brains of humans and animals with neurodegenerative diseases--beta-protein from alzheimer's disease (ad) and down's syndrome, and prion protein (prp) from scrapie and creutzfeldt-jakob disease (cjd). |
1988-10-27 |
2023-08-11 |
rabbit |
| J K Blusztajn, M Liscovitch, U I Richardso. Synthesis of acetylcholine from choline derived from phosphatidylcholine in a human neuronal cell line. Proceedings of the National Academy of Sciences of the United States of America. vol 84. issue 15. 1987-08-26. PMID:3474663. |
the selective vulnerability of cholinergic neurons in certain neurodegenerative diseases (e.g., alzheimer disease, motor neuron disorders) might result from the abnormally accelerated liberation of choline (to be used as precursor of accho) from membrane phospholipids, resulting in altered membrane composition and function and compromised neuronal viability. |
1987-08-26 |
2023-08-11 |
human |
| D M Armstrong, S LeRoy, D Shields, R D Terr. Somatostatin-like immunoreactivity within neuritic plaques. Brain research. vol 338. issue 1. 1985-10-03. PMID:2862952. |
alzheimer's disease or senile dementia of the alzheimer type (sdat) is a progressive neurodegenerative disease that is characterized pathologically by two types of microscopic lesions in the neocortex: the neurofibrillary tangle and neuritic plaque. |
1985-10-03 |
2023-08-11 |
Not clear |
| S E Hays, S M Pau. CCK receptors and human neurological disease. Life sciences. vol 31. issue 4. 1983-01-19. PMID:6292647. |
these findings indicate that cck receptor loss is unique to specific neurodegenerative disease(s), and that cck may be involved in the symptoms of huntington's disease but is not implicated in the neuropathology of alzheimer's dementia. |
1983-01-19 |
2023-08-12 |
human |