| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Min Chen, Jing Wang, Cairong Min. Buyuan Congnao decoction decreases hippocampal beta-amyloid expression in a rat model of Alzheimer's disease. Neural regeneration research. vol 7. issue 9. 2015-03-06. PMID:25745460. |
buyuan congnao decoction decreases hippocampal beta-amyloid expression in a rat model of alzheimer's disease. |
2015-03-06 |
2023-08-13 |
rat |
| Min Chen, Jing Wang, Cairong Min. Buyuan Congnao decoction decreases hippocampal beta-amyloid expression in a rat model of Alzheimer's disease. Neural regeneration research. vol 7. issue 9. 2015-03-06. PMID:25745460. |
a mixture of ibotenic acid and β-amyloid 1-42 was injected into the hippocampus of a rat model of alzheimer's disease, followed by intragastric administration of a traditional chinese medicine buyuan congnao decoction (main components included radix astragali, radix polygoni multiflori preparata, rhizoma acori talarinowii, radix polygalae, fructus alpiniae oxyphyllae, and radix glycyrrhizae preparata) and a piracetam suspension. |
2015-03-06 |
2023-08-13 |
rat |
| Min Chen, Jing Wang, Cairong Min. Buyuan Congnao decoction decreases hippocampal beta-amyloid expression in a rat model of Alzheimer's disease. Neural regeneration research. vol 7. issue 9. 2015-03-06. PMID:25745460. |
these findings suggested that compound prescription of buyuan congnao decoction, similar to the curative effects of piracetam, decreased hippocampal β-amyloid expression in a rat model of alzheimer's disease, as well as improved learning and memory. |
2015-03-06 |
2023-08-13 |
rat |
| Kate E Macdonald, Kelvin K Leung, Jonathan W Bartlett, Melanie Blair, Ian B Malone, Josephine Barnes, Sebastien Ourselin, Nick C Fo. Automated template-based hippocampal segmentations from MRI: the effects of 1.5T or 3T field strength on accuracy. Neuroinformatics. vol 12. issue 3. 2015-03-02. PMID:24395058. |
hippocampal volumetric measures may be useful for alzheimer's disease (ad) diagnosis and disease tracking; however, manual segmentation of the hippocampus is labour-intensive. |
2015-03-02 |
2023-08-12 |
Not clear |
| Jie Shi, Natasha Leporé, Boris A Gutman, Paul M Thompson, Leslie C Baxter, Richard J Caselli, Yalin Wan. Genetic influence of apolipoprotein E4 genotype on hippocampal morphometry: An N = 725 surface-based Alzheimer's disease neuroimaging initiative study. Human brain mapping. vol 35. issue 8. 2015-02-27. PMID:24453132. |
genetic influence of apolipoprotein e4 genotype on hippocampal morphometry: an n = 725 surface-based alzheimer's disease neuroimaging initiative study. |
2015-02-27 |
2023-08-12 |
human |
| Jie Shi, Natasha Leporé, Boris A Gutman, Paul M Thompson, Leslie C Baxter, Richard J Caselli, Yalin Wan. Genetic influence of apolipoprotein E4 genotype on hippocampal morphometry: An N = 725 surface-based Alzheimer's disease neuroimaging initiative study. Human brain mapping. vol 35. issue 8. 2015-02-27. PMID:24453132. |
here we examined the effect of apoe e4 on hippocampal morphometry in a large imaging database-the alzheimer's disease neuroimaging initiative (adni). |
2015-02-27 |
2023-08-12 |
human |
| Amelia A Assareh, Olivier Piguet, Tanya C Lye, Karen A Mather, Gerald A Broe, Peter R Schofield, Perminder S Sachdev, John B J Kwo. Association of SORL1 gene variants with hippocampal and cerebral atrophy and Alzheimer's disease. Current Alzheimer research. vol 11. issue 6. 2015-02-26. PMID:24938503. |
association of sorl1 gene variants with hippocampal and cerebral atrophy and alzheimer's disease. |
2015-02-26 |
2023-08-13 |
Not clear |
| Zhiqun Wang, Peipeng Liang, Zhilian Zhao, Ying Han, Haiqing Song, Jianyang Xu, Jie Lu, Kuncheng L. Acupuncture modulates resting state hippocampal functional connectivity in Alzheimer disease. PloS one. vol 9. issue 3. 2015-02-21. PMID:24603951. |
acupuncture modulates resting state hippocampal functional connectivity in alzheimer disease. |
2015-02-21 |
2023-08-12 |
human |
| Zhiqun Wang, Peipeng Liang, Zhilian Zhao, Ying Han, Haiqing Song, Jianyang Xu, Jie Lu, Kuncheng L. Acupuncture modulates resting state hippocampal functional connectivity in Alzheimer disease. PloS one. vol 9. issue 3. 2015-02-21. PMID:24603951. |
our objective is to clarify the effects of acupuncture on hippocampal connectivity in patients with alzheimer disease (ad) using functional magnetic resonance imaging (fmri). |
2015-02-21 |
2023-08-12 |
human |
| Shijie Song, Xinming Wang, Vasyl Sava, Edwin J Weeber, Juan Sanchez-Ramo. In vivo administration of granulocyte colony-stimulating factor restores long-term depression in hippocampal slices prepared from transgenic APP/PS1 mice. Journal of neuroscience research. vol 92. issue 8. 2015-02-21. PMID:24664800. |
g-csf has been reported to decrease amyloid burden significantly, promote hippocampal neurogenesis, and improve spatial learning in a mouse model of alzheimer's disease. |
2015-02-21 |
2023-08-12 |
mouse |
| Scott A Smal. Isolating pathogenic mechanisms embedded within the hippocampal circuit through regional vulnerability. Neuron. vol 84. issue 1. 2015-02-20. PMID:25277453. |
neuroimaging tools have been optimized to interrogate the malfunctioning hippocampal circuit, and by applying these tools to patients in the earliest stages of disease and to animal models, patterns of regional vulnerability have been established for alzheimer's disease, schizophrenia, and cognitive aging. |
2015-02-20 |
2023-08-13 |
Not clear |
| Elizabeth G Kehoe, Dervla Farrell, Claudia Metzler-Baddeley, Brian A Lawlor, Rose Anne Kenny, Declan Lyons, Jonathan P McNulty, Paul G Mullins, Damien Coyle, Arun L Bokd. Fornix White Matter is Correlated with Resting-State Functional Connectivity of the Thalamus and Hippocampus in Healthy Aging but Not in Mild Cognitive Impairment - A Preliminary Study. Frontiers in aging neuroscience. vol 7. 2015-02-20. PMID:25698967. |
in this study, we wished to examine the relationship between the structural connectivity of the fornix, a white matter (wm) tract in the limbic system, which is affected in amnestic mild cognitive impairment (amci) and alzheimer's disease, and the resting-state functional connectivity (fc) of two key related subcortical structures, the thalamus, and hippocampus. |
2015-02-20 |
2023-08-13 |
Not clear |
| Ya-Hsin Hsiao, Hui-Chi Hung, Shun-Hua Chen, Po-Wu Gea. Social interaction rescues memory deficit in an animal model of Alzheimer's disease by increasing BDNF-dependent hippocampal neurogenesis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 49. 2015-02-19. PMID:25471562. |
social interaction rescues memory deficit in an animal model of alzheimer's disease by increasing bdnf-dependent hippocampal neurogenesis. |
2015-02-19 |
2023-08-13 |
mouse |
| Zsuzsanna Tucsek, Peter Toth, Stefano Tarantini, Danuta Sosnowska, Tripti Gautam, Junie P Warrington, Cory B Giles, Jonathan D Wren, Akos Koller, Praveen Ballabh, William E Sonntag, Zoltan Ungvari, Anna Csisza. Aging exacerbates obesity-induced cerebromicrovascular rarefaction, neurovascular uncoupling, and cognitive decline in mice. The journals of gerontology. Series A, Biological sciences and medical sciences. vol 69. issue 11. 2015-02-13. PMID:24895269. |
obesity in aging exacerbates blood-brain barrier disruption, neuroinflammation and oxidative stress in the mouse hippocampus: effects on expression of genes involved in beta-amyloid generation and alzheimer's disease. |
2015-02-13 |
2023-08-13 |
mouse |
| Laura E M Wisse, Geert Jan Biessels, Sophie M Heringa, Hugo J Kuijf, Dineke H L Koek, Peter R Luijten, Mirjam I Geerling. Hippocampal subfield volumes at 7T in early Alzheimer's disease and normal aging. Neurobiology of aging. vol 35. issue 9. 2015-02-12. PMID:24684788. |
hippocampal subfield volumes at 7t in early alzheimer's disease and normal aging. |
2015-02-12 |
2023-08-12 |
Not clear |
| Laura E M Wisse, Geert Jan Biessels, Sophie M Heringa, Hugo J Kuijf, Dineke H L Koek, Peter R Luijten, Mirjam I Geerling. Hippocampal subfield volumes at 7T in early Alzheimer's disease and normal aging. Neurobiology of aging. vol 35. issue 9. 2015-02-12. PMID:24684788. |
we compared hippocampal subfield and entorhinal cortex (erc) volumes between patients with mild cognitive impairment (mci), alzheimer's disease (ad), and controls without cognitive impairment. |
2015-02-12 |
2023-08-12 |
Not clear |
| Xue-Qin Hou, Dian-Wei Wu, Chun-Xia Zhang, Rong Yan, Cong Yang, Cui-Ping Rong, Lei Zhang, Xiang Chang, Ru-Yu Su, Shi-Jie Zhang, Wen-Qing He, Zhao Qu, Shi Li, Zi-Ren Su, Yun-Bo Chen, Qi Wang, Shu-Huan Fan. Bushen‑Yizhi formula ameliorates cognition deficits and attenuates oxidative stress‑related neuronal apoptosis in scopolamine‑induced senescence in mice. International journal of molecular medicine. vol 34. issue 2. 2015-02-12. PMID:24919922. |
the present study aimed to investigate the effects of bsyz on learning and memory abilities, as well as oxidative stress and neuronal apoptosis in the hippocampus of scopolamine (scop)‑induced senescence in mice, in order to reveal whether bsyz is a potential therapeutic agent for alzheimer's disease (ad). |
2015-02-12 |
2023-08-13 |
mouse |
| Monica K Wetzel-Smith, Julie Hunkapiller, Tushar R Bhangale, Karpagam Srinivasan, Janice A Maloney, Jasvinder K Atwal, Susan M Sa, Murat B Yaylaoglu, Oded Foreman, Ward Ortmann, Nisha Rathore, David V Hansen, Marc Tessier-Lavigne, Richard Mayeux, Margaret Pericak-Vance, Jonathan Haines, Lindsay A Farrer, Gerard D Schellenberg, Alison Goate, Timothy W Behrens, Carlos Cruchaga, Ryan J Watts, Robert R Graha. A rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell death. Nature medicine. vol 20. issue 12. 2015-02-10. PMID:25419706. |
on the basis of these data and the enriched hippocampal expression of unc5c in the adult nervous system, we propose that one possible mechanism in which t835m unc5c contributes to the risk of alzheimer's disease is by increasing susceptibility to neuronal cell death, particularly in vulnerable regions of the alzheimer's disease brain. |
2015-02-10 |
2023-08-13 |
human |
| Gang Luo, Min Liu, Jue He, Huining Guo, Mengzhou Xue, Xinchun Wang, Xin-Min L. Quetiapine attenuates recognition memory impairment and hippocampal oxidative stress in a transgenic mouse model of Alzheimer's disease. Neuroreport. vol 25. issue 9. 2015-02-09. PMID:24642954. |
quetiapine attenuates recognition memory impairment and hippocampal oxidative stress in a transgenic mouse model of alzheimer's disease. |
2015-02-09 |
2023-08-12 |
mouse |
| Derek L G Hill, Adam J Schwarz, Maria Isaac, Luca Pani, Spiros Vamvakas, Robert Hemmings, Maria C Carrillo, Peng Yu, Jia Sun, Laurel Beckett, Marina Boccardi, James Brewer, Martha Brumfield, Marc Cantillon, Patricia E Cole, Nick Fox, Giovanni B Frisoni, Clifford Jack, Thomas Kelleher, Feng Luo, Gerald Novak, Paul Maguire, Richard Meibach, Patricia Patterson, Lisa Bain, Cristina Sampaio, David Raunig, Holly Soares, Joyce Suhy, Huanli Wang, Robin Wolz, Diane Stephenso. Coalition Against Major Diseases/European Medicines Agency biomarker qualification of hippocampal volume for enrichment of clinical trials in predementia stages of Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 10. issue 4. 2015-02-09. PMID:24985687. |
coalition against major diseases/european medicines agency biomarker qualification of hippocampal volume for enrichment of clinical trials in predementia stages of alzheimer's disease. |
2015-02-09 |
2023-08-13 |
Not clear |