| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wen-Dan Yang, Wan-Qing Guo, Chang-Hui Qian, Qian Xu, Xue-Hua Zheng, Wei-Guo Don. [Effect of early intervention of electroacupuncture on learning-memory ability and level of hippocampal phosphorylated Tau protein in SAMP8 mice]. Zhongguo zhen jiu = Chinese acupuncture & moxibustion. vol 40. issue 1. 2020-01-29. PMID:31930902. |
to explore the effect of early intervention electroacupuncture (ea) at "baihui" (gv 20), "dazhui" (gv 14) and "shenshu" (bl 23) on the learning-memory ability and the expression of phosphorylated tau protein in the hippocampus of samp8 mice, so as to provide reference for the intervening period of ea for alzheimer's disease (ad). |
2020-01-29 |
2023-08-13 |
mouse |
| Vincent Planche, Pierrick Coupé, Catherine Helmer, Mélanie Le Goff, Helene Amieva, François Tison, Jean-François Dartigues, Gwénaëlle Cathelin. Evolution of brain atrophy subtypes during aging predicts long-term cognitive decline and future Alzheimer's clinical syndrome. Neurobiology of aging. vol 79. 2020-01-27. PMID:31026619. |
in cox proportional-hazards models, "hippocampal predominant atrophy" was associated with an increased risk of developing alzheimer's clinical syndrome over time (hazard ratio = 5.73; 95% ci 2.71-12.15), independently of age and apoe4 genotype, the 2 other significant predictive factors. |
2020-01-27 |
2023-08-13 |
human |
| Vincent Planche, Pierrick Coupé, Catherine Helmer, Mélanie Le Goff, Helene Amieva, François Tison, Jean-François Dartigues, Gwénaëlle Cathelin. Evolution of brain atrophy subtypes during aging predicts long-term cognitive decline and future Alzheimer's clinical syndrome. Neurobiology of aging. vol 79. 2020-01-27. PMID:31026619. |
as a possible surrogate of confined tauopathy and early alzheimer's disease pathology, future studies should consider the definition of "hippocampal predominant atrophy" based on hippocampal-to-cortical volume ratio evolution rather than hippocampal volume alone. |
2020-01-27 |
2023-08-13 |
human |
| Li Wang, Yansong Zheng, Xiaoxiao Gao, Yingchun Liu, Xiaoqing Yo. Retinoid X receptor ligand regulates RXRα/Nur77-dependent apoptosis via modulating its nuclear export and mitochondrial targeting. International journal of clinical and experimental pathology. vol 10. issue 11. 2020-01-26. PMID:31966420. |
thus, we detected the changes of the expression and subcellular localization of rxrα/nur77 and the apoptotic rate of neuroblastoma cells, sh-sy5y cells and nerve cells in c57bl/6 mouse hippocampus in alzheimer's disease pathologic condition, and investigated the effect of rxrα exporting inhibition caused by 9-cis-ra on the apoptosis of neurons. |
2020-01-26 |
2023-08-13 |
mouse |
| Ruoxuan Cui, Manhua Li. Hippocampus Analysis by Combination of 3-D DenseNet and Shapes for Alzheimer's Disease Diagnosis. IEEE journal of biomedical and health informatics. vol 23. issue 5. 2020-01-17. PMID:30475734. |
hippocampus analysis by combination of 3-d densenet and shapes for alzheimer's disease diagnosis. |
2020-01-17 |
2023-08-13 |
human |
| Ruoxuan Cui, Manhua Li. Hippocampus Analysis by Combination of 3-D DenseNet and Shapes for Alzheimer's Disease Diagnosis. IEEE journal of biomedical and health informatics. vol 23. issue 5. 2020-01-17. PMID:30475734. |
hippocampus is one of the first involved regions in alzheimer's disease (ad) and mild cognitive impairment (mci), a prodromal stage of ad. |
2020-01-17 |
2023-08-13 |
human |
| Natalie M Zahr, Kilian M Pohl, Manojkumar Saranathan, Edith V Sullivan, Adolf Pfefferbau. Hippocampal subfield CA2+3 exhibits accelerated aging in Alcohol Use Disorder: A preliminary study. NeuroImage. Clinical. vol 22. 2020-01-17. PMID:30904825. |
for example, damage to hippocampal subfield cornu ammonis 1 (ca1) is often reported in alzheimer's disease (ad), whereas deficits in ca4/dentate gyrus are described in response to stress and trauma. |
2020-01-17 |
2023-08-13 |
human |
| Sujin Kim, Yunkwon Nam, Yu-On Jeong, Hyun Ha Park, Seong-Kyung Lee, Soo Jung Shin, Haram Jung, Byeong-Hyeon Kim, Sang Bum Hong, Yong Ho Park, Jihee Kim, Jaemin Yu, Doo-Han Yoo, Sun-Hyun Park, Seong Gak Jeon, Minho Moo. Topographical Visualization of the Reciprocal Projection between the Medial Septum and the Hippocampus in the 5XFAD Mouse Model of Alzheimer's Disease. International journal of molecular sciences. vol 20. issue 16. 2020-01-17. PMID:31426329. |
topographical visualization of the reciprocal projection between the medial septum and the hippocampus in the 5xfad mouse model of alzheimer's disease. |
2020-01-17 |
2023-08-13 |
mouse |
| Masayuki Shintaku, Hiroyuki Yabata, Eri Tanaka, Masanori Shiohara, Ryoji Kushim. Amyotrophic lateral sclerosis with appearance of many skein-like inclusions in anterior horn cells. International journal of clinical and experimental pathology. vol 12. issue 11. 2020-01-17. PMID:31933814. |
an alzheimer type tau-pathology was found mainly in the hippocampus (braak stage iii), and many argyrophilic grains were distributed in the limbic area. |
2020-01-17 |
2023-08-13 |
Not clear |
| Yang Liu, Yan Gao, Ke-Xin Li, Wei Xu. Pharmacokinetics and acetylcholine releasing effects of ginsenoside Rg1 in hippocampus of beta-amyloid model rats. Journal of Asian natural products research. vol 21. issue 8. 2020-01-13. PMID:30501509. |
this study aimed at investigating the pharmacokinetics (pk) and acetylcholine (ach) releasing effects of ginsenoside rg1 in hippocampus (hip) of soluble oligomeric assemblies of amyloid beta (addls) induced alzheimer's disease (ad) model rats. |
2020-01-13 |
2023-08-13 |
rat |
| Tianyi Wang, Jing Chen, Yue Hou, Yang Yu, Bing Wan. BAP31 deficiency contributes to the formation of amyloid-β plaques in Alzheimer's disease by reducing the stability of RTN3. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 33. issue 4. 2020-01-13. PMID:30596517. |
to further explore how bap31 is involved in alzheimer's disease (ad), conditional knockout mice with targeted bap31 deletion (b-ko) in the hippocampus and cerebral cortex were generated and hybridized with amyloid precursor protein (app) ps1 transgenic (ad model) mice to obtain b-ko-ad mice. |
2020-01-13 |
2023-08-13 |
mouse |
| Sarah Lemprièr. Birth of hippocampal neurons declines in Alzheimer disease. Nature reviews. Neurology. vol 15. issue 5. 2020-01-10. PMID:30953034. |
birth of hippocampal neurons declines in alzheimer disease. |
2020-01-10 |
2023-08-13 |
Not clear |
| Sarah Houben, Karelle Leroy, Kunie Ando, Zehra Yilmaz, Cyprien Widomski, Luc Buée, Jean-Pierre Brio. Genetic ablation of tau in postnatal neurons rescues decreased adult hippocampal neurogenesis in a tauopathy model. Neurobiology of disease. vol 127. 2020-01-09. PMID:30818066. |
impaired adult hippocampal neurogenesis has been reported as a feature of alzheimer's disease and other tauopathies and might contribute to defects in learning and memory in these diseases. |
2020-01-09 |
2023-08-13 |
mouse |
| Chrysoula Dioli, Patrícia Patrício, Nuno Sousa, Nikolaos Kokras, Christina Dalla, Sara Guerreiro, Miguel A Santos-Silva, Ana Cristina Rego, Luísa Pinto, Elisabete Ferreiro, Ioannis Sotiropoulo. Chronic stress triggers divergent dendritic alterations in immature neurons of the adult hippocampus, depending on their ultimate terminal fields. Translational psychiatry. vol 9. issue 1. 2020-01-09. PMID:31028242. |
chronic stress, a suggested precipitant of brain pathologies, such as depression and alzheimer's disease, is known to impact on brain plasticity by causing neuronal remodeling as well as neurogenesis suppression in the adult hippocampus. |
2020-01-09 |
2023-08-13 |
Not clear |
| Dusan Hirjak, Fabio Sambataro, Barbara Remmele, Katharina M Kubera, Johannes Schröder, Ulrich Seidl, Anne K Thomann, Klaus H Maier-Hein, Robert C Wolf, Philipp A Thoman. The relevance of hippocampal subfield integrity and clock drawing test performance for the diagnosis of Alzheimer's disease and mild cognitive impairment. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 20. issue 3. 2020-01-02. PMID:28721741. |
the relevance of hippocampal subfield integrity and clock drawing test performance for the diagnosis of alzheimer's disease and mild cognitive impairment. |
2020-01-02 |
2023-08-13 |
Not clear |
| Gregory A Jicha, Peter T Nelso. Hippocampal Sclerosis, Argyrophilic Grain Disease, and Primary Age-Related Tauopathy. Continuum (Minneapolis, Minn.). vol 25. issue 1. 2020-01-02. PMID:30707194. |
hippocampal sclerosis, argyrophilic grain disease, and primary age-related tauopathy are common alzheimer disease mimics that currently lack clinical diagnostic criteria. |
2020-01-02 |
2023-08-13 |
Not clear |
| Gregory A Jicha, Peter T Nelso. Hippocampal Sclerosis, Argyrophilic Grain Disease, and Primary Age-Related Tauopathy. Continuum (Minneapolis, Minn.). vol 25. issue 1. 2020-01-02. PMID:30707194. |
increased understanding of these pathologic entities is important for the neurologist who may encounter patients with an unusually slowly progressive degenerative dementia that may appear to meet criteria for alzheimer disease but who progress to develop symptoms that are unusual for classic alzheimer disease recent findings: hippocampal sclerosis has traditionally been associated with hypoxic/ischemic injury and poorly controlled epilepsy, but it is now recognized that hippocampal sclerosis may also be associated with a unique degenerative disease of aging or may be an associated pathologic finding in many cases of frontotemporal lobar degeneration. |
2020-01-02 |
2023-08-13 |
Not clear |
| S Akila Parvathy Dharshini, Y-H Taguchi, M Michael Gromih. Exploring the selective vulnerability in Alzheimer disease using tissue specific variant analysis. Genomics. vol 111. issue 4. 2019-12-30. PMID:29879491. |
in alzheimer's disease (ad), neurons in hippocampus situated in medial temporal lobe are immensely damaged. |
2019-12-30 |
2023-08-13 |
Not clear |
| Sona Hurtz, Nicole Chow, Amity E Watson, Johanne H Somme, Naira Goukasian, Kristy S Hwang, John Morra, David Elashoff, Sujuan Gao, Ronald C Petersen, Paul S Aisen, Paul M Thompson, Liana G Apostolov. Automated and manual hippocampal segmentation techniques: Comparison of results, reproducibility and clinical applicability. NeuroImage. Clinical. vol 21. 2019-12-26. PMID:30553759. |
imaging techniques used to measure hippocampal atrophy are key to understanding the clinical progression of alzheimer's disease (ad). |
2019-12-26 |
2023-08-13 |
human |
| Mohamed Salah Khlif, Natalia Egorova, Emilio Werden, Alberto Redolfi, Marina Boccardi, Charles S DeCarli, Evan Fletcher, Baljeet Singh, Qi Li, Laura Bird, Amy Brodtman. A comparison of automated segmentation and manual tracing in estimating hippocampal volume in ischemic stroke and healthy control participants. NeuroImage. Clinical. vol 21. 2019-12-26. PMID:30606656. |
the automation of hippocampal segmentation has been investigated in normal aging, epilepsy, and in alzheimer's disease. |
2019-12-26 |
2023-08-13 |
human |