| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Kanai, M Shizuka, K Urakami, E Matsubara, Y Harigaya, K Okamoto, M Shoj. Apolipoprotein E4 accelerates dementia and increases cerebrospinal fluid tau levels in Alzheimer's disease. Neuroscience letters. vol 267. issue 1. 1999-12-06. PMID:10400250. |
the apoe epsilon4 allele accelerates the progression of dementia and increases the levels of csf tau in ad patients. |
1999-12-06 |
2023-08-12 |
Not clear |
| L Buée, A Delacourt. Comparative biochemistry of tau in progressive supranuclear palsy, corticobasal degeneration, FTDP-17 and Pick's disease. Brain pathology (Zurich, Switzerland). vol 9. issue 4. 1999-11-16. PMID:10517507. |
finally, recent findings provide a direct link between a genetic defect in tau and its abnormal aggregation into filaments in fronto-temporal dementia with parkinsonism linked to chromosome 17, demonstrating that tau aggregation is sufficient for nerve cell degeneration. |
1999-11-16 |
2023-08-12 |
human |
| D A Grimes, C B Bergeron, A E Lan. Motor neuron disease-inclusion dementia presenting as cortical-basal ganglionic degeneration. Movement disorders : official journal of the Movement Disorder Society. vol 14. issue 4. 1999-11-02. PMID:10435507. |
the motor neuron disease-inclusion dementia (mndid) subtype is characterized by the accumulation of specific intraneuronal ubiquitin-immunoreactive inclusions with the complete absence of tau immunoreactivity. |
1999-11-02 |
2023-08-12 |
Not clear |
| M Yasuda, T Kawamata, O Komure, S Kuno, I D'Souza, P Poorkaj, J Kawai, S Tanimukai, Y Yamamoto, H Hasegawa, M Sasahara, F Hazama, G D Schellenberg, C Tanak. A mutation in the microtubule-associated protein tau in pallido-nigro-luysian degeneration. Neurology. vol 53. issue 4. 1999-10-29. PMID:10489057. |
we detected a missense mutation in exon 10 of tau that causes a substitution at codon 279 (n279k) in a japanese patient with a familial background of parkinsonism and dementia originally described as pallido-nigro-luysian degeneration. |
1999-10-29 |
2023-08-12 |
Not clear |
| M B Delisle, J R Murrell, R Richardson, J A Trofatter, O Rascol, X Soulages, M Mohr, P Calvas, B Ghett. A mutation at codon 279 (N279K) in exon 10 of the Tau gene causes a tauopathy with dementia and supranuclear palsy. Acta neuropathologica. vol 98. issue 1. 1999-09-24. PMID:10412802. |
a mutation at codon 279 (n279k) in exon 10 of the tau gene causes a tauopathy with dementia and supranuclear palsy. |
1999-09-24 |
2023-08-12 |
Not clear |
| M B Delisle, J R Murrell, R Richardson, J A Trofatter, O Rascol, X Soulages, M Mohr, P Calvas, B Ghett. A mutation at codon 279 (N279K) in exon 10 of the Tau gene causes a tauopathy with dementia and supranuclear palsy. Acta neuropathologica. vol 98. issue 1. 1999-09-24. PMID:10412802. |
among families, the symptomatology appears to vary in quality and severity in relation to the specific tau gene mutation and often may include parkinsonism, supranuclear palsies, and/or myoclonus, in addition to dementia. |
1999-09-24 |
2023-08-12 |
Not clear |
| H Houlden, M Baker, J Adamson, A Grover, S Waring, D Dickson, T Lynch, B Boeve, R C Petersen, S Pickering-Brown, F Owen, D Neary, D Craufurd, J Snowden, D Mann, M Hutto. Frequency of tau mutations in three series of non-Alzheimer's degenerative dementia. Annals of neurology. vol 46. issue 2. 1999-08-31. PMID:10443890. |
frequency of tau mutations in three series of non-alzheimer's degenerative dementia. |
1999-08-31 |
2023-08-12 |
Not clear |
| H Houlden, M Baker, J Adamson, A Grover, S Waring, D Dickson, T Lynch, B Boeve, R C Petersen, S Pickering-Brown, F Owen, D Neary, D Craufurd, J Snowden, D Mann, M Hutto. Frequency of tau mutations in three series of non-Alzheimer's degenerative dementia. Annals of neurology. vol 46. issue 2. 1999-08-31. PMID:10443890. |
in this study we assessed the genetic contribution of tau mutations to three patient series with non-alzheimer's (non-ad) degenerative dementia. |
1999-08-31 |
2023-08-12 |
Not clear |
| H Houlden, M Baker, J Adamson, A Grover, S Waring, D Dickson, T Lynch, B Boeve, R C Petersen, S Pickering-Brown, F Owen, D Neary, D Craufurd, J Snowden, D Mann, M Hutto. Frequency of tau mutations in three series of non-Alzheimer's degenerative dementia. Annals of neurology. vol 46. issue 2. 1999-08-31. PMID:10443890. |
comparing the three clinical series: in the stringently diagnosed manchester frontotemporal dementia series, tau mutations were present in 13.6% of cases (three splice-site mutations); in the clinicopathological referral series that used more general inclusion criteria, 3 cases with p301l mutations were observed, which represents a lower mutation frequency of 3.6% (9.4% in familial cases); in contrast, tau mutations were not detected in the minnesota community-based dementia series, suggesting the occurrence of these mutations in dementia generally is rare (<0.2%). |
1999-08-31 |
2023-08-12 |
Not clear |
| M Tolnay, A Probs. REVIEW: tau protein pathology in Alzheimer's disease and related disorders. Neuropathology and applied neurobiology. vol 25. issue 3. 1999-08-26. PMID:10417659. |
however, tau containing filamentous inclusions in neurones and/or glial cells also define a number of other neurodegenerative disorders clinically characterized by dementia and/or motor syndromes. |
1999-08-26 |
2023-08-12 |
Not clear |
| F Crawford, M Freeman, T Town, D Fallin, M Gold, R Duara, M Mulla. No genetic association between polymorphisms in the Tau gene and Alzheimer's disease in clinic or population based samples. Neuroscience letters. vol 266. issue 3. 1999-08-25. PMID:10465706. |
mutations in the tau protein gene have recently been found to cause familial fronto-temporal dementia in a number of kindreds demonstrating linkage to chromosome 17. |
1999-08-25 |
2023-08-12 |
Not clear |
| T Frappier, N S Liang, K Brown, C L Leung, T Lynch, R K Liem, M L Shelansk. Abnormal microtubule packing in processes of SF9 cells expressing the FTDP-17 V337M tau mutation. FEBS letters. vol 455. issue 3. 1999-08-16. PMID:10437785. |
mutations in the gene for the microtubule associated protein, tau have been identified for fronto-temporal dementia with parkinsonism linked to chromosome 17 (ftdp-17). |
1999-08-16 |
2023-08-12 |
Not clear |
| A Grover, H Houlden, M Baker, J Adamson, J Lewis, G Prihar, S Pickering-Brown, K Duff, M Hutto. 5' splice site mutations in tau associated with the inherited dementia FTDP-17 affect a stem-loop structure that regulates alternative splicing of exon 10. The Journal of biological chemistry. vol 274. issue 21. 1999-07-09. PMID:10329720. |
5' splice site mutations in tau associated with the inherited dementia ftdp-17 affect a stem-loop structure that regulates alternative splicing of exon 10. |
1999-07-09 |
2023-08-12 |
Not clear |
| A Grover, H Houlden, M Baker, J Adamson, J Lewis, G Prihar, S Pickering-Brown, K Duff, M Hutto. 5' splice site mutations in tau associated with the inherited dementia FTDP-17 affect a stem-loop structure that regulates alternative splicing of exon 10. The Journal of biological chemistry. vol 274. issue 21. 1999-07-09. PMID:10329720. |
missense and splice site mutations in the microtubule-associated protein tau gene were recently found associated with fronto-temporal dementia and parkinsonism linked to chromosome 17 (poorkaj et al. |
1999-07-09 |
2023-08-12 |
Not clear |
| O Bugiani, J R Murrell, G Giaccone, M Hasegawa, G Ghigo, M Tabaton, M Morbin, A Primavera, F Carella, C Solaro, M Grisoli, M Savoiardo, M G Spillantini, F Tagliavini, M Goedert, B Ghett. Frontotemporal dementia and corticobasal degeneration in a family with a P301S mutation in tau. Journal of neuropathology and experimental neurology. vol 58. issue 6. 1999-07-07. PMID:10374757. |
the tau gene has been found to be the locus of dementia with rigidity linked to chromosome 17. |
1999-07-07 |
2023-08-12 |
Not clear |
| Y Morikawa, H Arai, S Matsushita, M Kato, S Higuchi, M Miura, H Kawakami, M Higuchi, N Okamura, M Tashiro, T Matsui, H Sasak. Cerebrospinal fluid tau protein levels in demented and nondemented alcoholics. Alcoholism, clinical and experimental research. vol 23. issue 4. 1999-06-28. PMID:10235290. |
the tau protein levels in cerebrospinal fluid (csf-tau) were examined in 27 patients with alcohol dependence (20 demented and 7 nondemented), 36 age and dementia severity-matched patients with alzheimer's disease (ad), and 23 age-matched normal control subjects. |
1999-06-28 |
2023-08-12 |
human |
| Y Morikawa, H Arai, S Matsushita, M Kato, S Higuchi, M Miura, H Kawakami, M Higuchi, N Okamura, M Tashiro, T Matsui, H Sasak. Cerebrospinal fluid tau protein levels in demented and nondemented alcoholics. Alcoholism, clinical and experimental research. vol 23. issue 4. 1999-06-28. PMID:10235290. |
these findings suggest that alcohol-induced organic brain disorders are a group of dementias that are characterized by normal csf-tau levels, and that the csf examination for tau in combination with other clinical findings may help in differentiating alcohol-induced organic brain disorders from ad. |
1999-06-28 |
2023-08-12 |
human |
| S Arawaka, M Usami, N Sahara, G D Schellenberg, G Lee, H Mor. The tau mutation (val337met) disrupts cytoskeletal networks of microtubules. Neuroreport. vol 10. issue 5. 1999-06-23. PMID:10321473. |
the missense point mutation found in the tau gene, which was segregated in a family with frontotemporal dementia with parkinsonism linked to chromosome 17 (ftdp-17), has proved to be the causal molecule for widely spread dementia diseases. |
1999-06-23 |
2023-08-12 |
Not clear |
| M Iijima, T Tabira, P Poorkaj, G D Schellenberg, J Q Trojanowski, V M Lee, M L Schmidt, K Takahashi, T Nabika, T Matsumoto, Y Yamashita, S Yoshioka, H Ishin. A distinct familial presenile dementia with a novel missense mutation in the tau gene. Neuroreport. vol 10. issue 3. 1999-06-10. PMID:10208578. |
a distinct familial presenile dementia with a novel missense mutation in the tau gene. |
1999-06-10 |
2023-08-12 |
Not clear |
| G A Jicha, J M Rockwood, B Berenfeld, M Hutton, P Davie. Altered conformation of recombinant frontotemporal dementia-17 mutant tau proteins. Neuroscience letters. vol 260. issue 3. 1999-05-17. PMID:10076890. |
recently, a series of both non-coding (intronic) and coding (exonic) mutations in the tau gene have been linked to a family of autosomal dominant dementias referred to as frontotemporal dementia-17. |
1999-05-17 |
2023-08-12 |
Not clear |