| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R E Tato, A Frank, A Hernan. Tau protein concentrations in cerebrospinal fluid of patients with dementia of the Alzheimer type. Journal of neurology, neurosurgery, and psychiatry. vol 59. issue 3. 1995-10-19. PMID:7545739. |
tau protein concentrations were measured in the csf of 23 patients with dementia of the alzheimer type (dat), 36 patients with multi-infarct dementia (mid), and 23 control subjects. |
1995-10-19 |
2023-08-12 |
human |
| S C Papasozomeno. Nuclear tau immunoreactivity in presenile dementia with motor neuron disease: a case report. Clinical neuropathology. vol 14. issue 2. 1995-08-16. PMID:7606894. |
nuclear tau immunoreactivity in presenile dementia with motor neuron disease: a case report. |
1995-08-16 |
2023-08-12 |
Not clear |
| S C Papasozomeno. Nuclear tau immunoreactivity in presenile dementia with motor neuron disease: a case report. Clinical neuropathology. vol 14. issue 2. 1995-08-16. PMID:7606894. |
we report for the first time localization of tau immunoreactivity with neuronal nuclei in an autopsy case of a 64-year-old white male with a 10-year history of presenile dementia with motor neuron disease. |
1995-08-16 |
2023-08-12 |
Not clear |
| H Mori, K Hosoda, E Matsubara, T Nakamoto, Y Furiya, R Endoh, M Usami, M Shoji, S Maruyama, S Hira. Tau in cerebrospinal fluids: establishment of the sandwich ELISA with antibody specific to the repeat sequence in tau. Neuroscience letters. vol 186. issue 2-3. 1995-07-10. PMID:7777192. |
the amount of tau was significantly elevated in csf of ad subjects compared with those of normal subjects and subjects with dementia of cerebrovascular disease, suggesting that tau in csf reflects the massive and continuous neuronal cell death in the ad brain. |
1995-07-10 |
2023-08-12 |
human |
| T W Smith, C F Lipp. Ki-67 immunoreactivity in Alzheimer's disease and other neurodegenerative disorders. Journal of neuropathology and experimental neurology. vol 54. issue 3. 1995-06-13. PMID:7745428. |
formalin-fixed, paraffin-embedded sections from autopsy cases of ad, down's syndrome with dementia and ad pathology (ds/ad), pick's disease (pid), progressive supranuclear palsy (psp), lewy body disease (lbd), parkinson's disease (pd), corticobasal degeneration (cbd), and young and aged normal brains, and from two surgically resected gangliogliomas were immunostained using antibodies to ki-67 (mib-1 clone equivalent) and tau (tau). |
1995-06-13 |
2023-08-12 |
Not clear |
| C Vigo-Pelfrey, P Seubert, R Barbour, C Blomquist, M Lee, D Lee, F Coria, L Chang, B Miller, I Lieberbur. Elevation of microtubule-associated protein tau in the cerebrospinal fluid of patients with Alzheimer's disease. Neurology. vol 45. issue 4. 1995-05-23. PMID:7723971. |
by this assay we measured that the ad population has a mean level of tau 50% greater than the non-ad dementia patients. |
1995-05-23 |
2023-08-12 |
human |
| R M Nitsch, G W Rebeck, M Deng, U I Richardson, M Tennis, D B Schenk, C Vigo-Pelfrey, I Lieberburg, R J Wurtman, B T Hyma. Cerebrospinal fluid levels of amyloid beta-protein in Alzheimer's disease: inverse correlation with severity of dementia and effect of apolipoprotein E genotype. Annals of neurology. vol 37. issue 4. 1995-05-15. PMID:7717688. |
to investigate whether clinical signs of ad are paralleled by changes in csf levels of these proteins, we correlated quantitative measures of dementia severity with csf concentrations of a beta, of apps, and of tau. |
1995-05-15 |
2023-08-12 |
human |
| R M Nitsch, G W Rebeck, M Deng, U I Richardson, M Tennis, D B Schenk, C Vigo-Pelfrey, I Lieberburg, R J Wurtman, B T Hyma. Cerebrospinal fluid levels of amyloid beta-protein in Alzheimer's disease: inverse correlation with severity of dementia and effect of apolipoprotein E genotype. Annals of neurology. vol 37. issue 4. 1995-05-15. PMID:7717688. |
in contrast, levels of apps and of tau did not correlate with dementia severity. |
1995-05-15 |
2023-08-12 |
human |
| G Koya, T Tabir. [Is a false image of the senile plaque in elderly Japanese with leprosy?--pathological findings on the immunohistology]. Nihon Rai Gakkai zasshi. vol 63. issue 2. 1995-03-08. PMID:7844063. |
we employed both tau protein and the divided beta protein, and each of protein is able to divide dementia and non-dementia into aged groups in leprosy. |
1995-03-08 |
2023-08-12 |
Not clear |
| J Cervós-Navarro, K Schumache. Neurofibrillary pathology in progressive supranuclear palsy (PSP). Journal of neural transmission. Supplementum. vol 42. 1994-12-22. PMID:7964685. |
in addition immunohistochemistry preparations using antibodies against tau and ubiquitin reveal an antigenic profile similar to early nft in dementia of alzheimer's type. |
1994-12-22 |
2023-08-12 |
Not clear |
| C R Harrington, R H Perry, E K Perry, J Hurt, I G McKeith, M Roth, C M Wischi. Senile dementia of Lewy body type and Alzheimer type are biochemically distinct in terms of paired helical filaments and hyperphosphorylated tau protein. Dementia (Basel, Switzerland). vol 5. issue 5. 1994-12-13. PMID:7951676. |
senile dementia of lewy body type and alzheimer type are biochemically distinct in terms of paired helical filaments and hyperphosphorylated tau protein. |
1994-12-13 |
2023-08-12 |
Not clear |
| C R Harrington, R H Perry, E K Perry, J Hurt, I G McKeith, M Roth, C M Wischi. Senile dementia of Lewy body type and Alzheimer type are biochemically distinct in terms of paired helical filaments and hyperphosphorylated tau protein. Dementia (Basel, Switzerland). vol 5. issue 5. 1994-12-13. PMID:7951676. |
we have used biochemical assays to examine cingulate and occipital cortices from age-matched cases of alzheimer's disease (ad; n = 12), senile dementia of the lewy body type (sdlt; n = 13), parkinson's disease (pd; 5 non-demented cases and 7 cognitively impaired cases) and controls (n = 11) for paired helical filaments (phfs), phosphorylated and normal tau protein and beta/a4-protein. |
1994-12-13 |
2023-08-12 |
Not clear |
| J Q Trojanowski, M L Schmidt, R W Shin, G T Bramblett, D Rao, V M Le. Altered tau and neurofilament proteins in neuro-degenerative diseases: diagnostic implications for Alzheimer's disease and Lewy body dementias. Brain pathology (Zurich, Switzerland). vol 3. issue 1. 1994-01-28. PMID:8269083. |
altered tau and neurofilament proteins in neuro-degenerative diseases: diagnostic implications for alzheimer's disease and lewy body dementias. |
1994-01-28 |
2023-08-12 |
human |
| P Vermersch, A Delacourte, F Javoy-Agid, J J Hauw, Y Agi. Dementia in Parkinson's disease: biochemical evidence for cortical involvement using the immunodetection of abnormal Tau proteins. Annals of neurology. vol 33. issue 5. 1993-06-21. PMID:8498822. |
dementia in parkinson's disease: biochemical evidence for cortical involvement using the immunodetection of abnormal tau proteins. |
1993-06-21 |
2023-08-12 |
human |
| W R Shankle, B H Landing, S M Ang, H Chui, G Villarreal-Engelhardt, C Zaro. Studies of the enteric nervous system in Alzheimer disease and other dementias of the elderly: enteric neurons in Alzheimer disease. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. vol 6. issue 1. 1993-03-04. PMID:8426853. |
enteric neurons in ad or the other dementias studied showed no definite stain with alz-50, a monoclonal antibody to a derivative of the microtubule-associated protein tau, which stains degenerating cerebral neurons in ad. |
1993-03-04 |
2023-08-12 |
rat |
| R Mena, Y Robitaille, A C Cuell. New patterns of intraneuronal accumulation of the microtubular binding domain of tau in granulovacuolar degeneration. Journal of geriatric psychiatry and neurology. vol 5. issue 3. 1992-09-16. PMID:1323297. |
sixteen brains from alzheimer's disease (ad) patients with varying duration of dementia were studied using the monoclonal antibody (mab) 6.423 raised against the three repeated domains of the tau protein, and named the paired helical filament (phf) core. |
1992-09-16 |
2023-08-11 |
Not clear |
| N Iwamoto, P C Emso. Demonstration of neurofibrillary tangles in parvalbumin-immunoreactive interneurones in the cerebral cortex of Alzheimer-type dementia brain. Neuroscience letters. vol 128. issue 1. 1991-11-05. PMID:1717900. |
the pathological changes occurring in a population of parvalbumin-like immunoreactive cerebral cortical interneurones in postmortem alzheimer-type dementia brain tissue were determined by double staining cerebral cortical sections for parvalbumin, tau and/or calpain-like immunoreactivities. |
1991-11-05 |
2023-08-11 |
Not clear |
| A J Barton, P J Harrison, A Najlerahim, J Heffernan, B McDonald, J R Robinson, D C Davies, W J Harrison, P Mitra, J A Hard. Increased tau messenger RNA in Alzheimer's disease hippocampus. The American journal of pathology. vol 137. issue 3. 1990-10-12. PMID:2119143. |
increased hippocampal expression of tau mrna also was present in cases of non-alzheimer's dementia. |
1990-10-12 |
2023-08-11 |
Not clear |
| S Flament, A Delacourte, P Delaère, C Duyckaerts, J J Hau. Correlation between microscopical changes and Tau 64 and 69 biochemical detection in senile dementia of the Alzheimer type. Tau 64 and 69 are reliable markers of the neurofibrillary degeneration. Acta neuropathologica. vol 80. issue 2. 1990-09-27. PMID:2117842. |
correlation between microscopical changes and tau 64 and 69 biochemical detection in senile dementia of the alzheimer type. |
1990-09-27 |
2023-08-11 |
Not clear |
| S Kuzuhara, Y Ihara, Y Toyokura, H Shimad. [A semiquantitative study on Alzheimer neurofibrillary tangles demonstrated immunohistochemically with anti-tau antibodies, in the brains of non-demented and demented old people]. No to shinkei = Brain and nerve. vol 41. issue 5. 1989-11-28. PMID:2508732. |
submitted for the study were 116 autopsy brains, from 65 non-demented people, 24 patients with dementia of alzheimer type (dat) and 27 patients with vascular dementia, aged between 50 s and 100 s. formalin-fixed, paraffin-embedded coronal sections of the brains at the level of the lateral geniculate body were immunohistochemically stained with the avidin-biotin-peroxidase complex procedure, using the anti-bodies to tau protein purified from human brains (anti-tau) as the primary antibodies. |
1989-11-28 |
2023-08-11 |
human |