| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hanna Wootz, Inga Hansson, Laura Korhonen, Ulla Näpänkangas, Dan Lindhol. Caspase-12 cleavage and increased oxidative stress during motoneuron degeneration in transgenic mouse model of ALS. Biochemical and biophysical research communications. vol 322. issue 1. 2004-09-30. PMID:15313203. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease characterized by loss of motoneurons in the spinal cord and brain stem. |
2004-09-30 |
2023-08-12 |
mouse |
| Michael McKinney, Katrina Williams, David Personett, Caroline Kent, David Bryan, John Gonzalez, Karen Baskervill. Pontine cholinergic neurons depend on three neuroprotection systems to resist nitrosative stress. Brain research. vol 1002. issue 1-2. 2004-06-24. PMID:14988039. |
brainstem cholinergic populations survive in neurodegenerative disease, while basal forebrain cholinergic neurons degenerate. |
2004-06-24 |
2023-08-12 |
rat |
| A J Fallgatter, B Neuhauser, M J Herrmann, A-C Ehlis, A Wagener, P Scheuerpflug, K Reiners, P Riedere. Far field potentials from the brain stem after transcutaneous vagus nerve stimulation. Journal of neural transmission (Vienna, Austria : 1996). vol 110. issue 12. 2004-05-05. PMID:14666414. |
recently, the vagus nerve has gained particular interest in neuropsychiatry, as neurodegenerative diseases like alzheimer's and parkinson's disease are supposed to affect the brainstem nuclei of the vagus nerve early in their course. |
2004-05-05 |
2023-08-12 |
human |
| J H Anderson, M C Yavuz, B M Kazar, P Christova, C M Gome. The vestibulo-ocular reflex and velocity storage in spinocerebellar ataxia 8. Archives italiennes de biologie. vol 140. issue 4. 2003-01-22. PMID:12228985. |
the autosomal dominant spinocerebellar ataxias (scas) are a group of neurodegenerative diseases characterized by progressive instability of posture and gait, incoordination, ocular motor dysfunction, and dysarthria due to degeneration of cerebellar and brainstem neurons. |
2003-01-22 |
2023-08-12 |
Not clear |
| Russell R Lonser, Stuart Walbridge, Kayhan Garmestani, John A Butman, Hugh A Walters, Alexander O Vortmeyer, Paul F Morrison, Martin W Brechbiel, Edward H Oldfiel. Successful and safe perfusion of the primate brainstem: in vivo magnetic resonance imaging of macromolecular distribution during infusion. Journal of neurosurgery. vol 97. issue 4. 2002-11-14. PMID:12405380. |
intrinsic disease processes of the brainstem (gliomas, neurodegenerative disease, and others) have remained difficult or impossible to treat effectively because of limited drug penetration across the blood-brainstem barrier with conventional delivery methods. |
2002-11-14 |
2023-08-12 |
Not clear |
| J P Pillion, S Naid. Auditory brainstem response findings in Rett syndrome: stability over time. The Journal of pediatrics. vol 137. issue 3. 2000-10-03. PMID:10969266. |
to determine whether changes consistent with the presence of white matter neurodegenerative disease would be observed in the auditory brainstem response (abr) in rett syndrome in conjunction with age advancement. |
2000-10-03 |
2023-08-12 |
Not clear |
| E J Olson, B F Boeve, M H Silbe. Rapid eye movement sleep behaviour disorder: demographic, clinical and laboratory findings in 93 cases. Brain : a journal of neurology. vol 123 ( Pt 2). 2000-02-25. PMID:10648440. |
although four scans showed brainstem pathology, all of these patients had apparently unrelated neurodegenerative diseases known to be associated with rbd. |
2000-02-25 |
2023-08-12 |
Not clear |
| H R Morris, N W Wood, A J Lee. Progressive supranuclear palsy (Steele-Richardson-Olszewski disease). Postgraduate medical journal. vol 75. issue 888. 2000-01-20. PMID:10621897. |
progressive supranuclear palsy is a neurodegenerative disease which affects the brainstem and basal ganglia. |
2000-01-20 |
2023-08-12 |
Not clear |
| R Dawson, E G Marschall, K C Chan, W J Millard, B Eppler, T A Patterso. Neurochemical and neurobehavioral effects of neonatal administration of beta-N-methylamino-L-alanine and 3,3'-iminodipropionitrile. Neurotoxicology and teratology. vol 20. issue 2. 1998-05-14. PMID:9536463. |
amyotrophic lateral sclerosis (als) is a progressive neurodegenerative disease that is characterized by a loss of motor neurons in the spinal cord, brain stem, and cortex. |
1998-05-14 |
2023-08-12 |
rat |
| N Tachibana, K Kimura, K Kitajima, A Shinde, J Kimura, H Shibasak. REM sleep motor dysfunction in multiple system atrophy: with special emphasis on sleep talk as its early clinical manifestation. Journal of neurology, neurosurgery, and psychiatry. vol 63. issue 5. 1998-01-20. PMID:9408115. |
various neurodegenerative diseases involving brainstem structures as one of the main pathological lesions are reported to be associated with rem sleep behaviour disorder. |
1998-01-20 |
2023-08-12 |
Not clear |
| P H Tu, M E Gurney, J P Julien, V M Lee, J Q Trojanowsk. Oxidative stress, mutant SOD1, and neurofilament pathology in transgenic mouse models of human motor neuron disease. Laboratory investigation; a journal of technical methods and pathology. vol 76. issue 4. 1997-05-09. PMID:9111507. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease that primarily affects motor neurons in the spinal cord and brain stem. |
1997-05-09 |
2023-08-12 |
mouse |
| S Kösel, C B Lücking, R Egensperger, P Mehraein, M B Graebe. Mitochondrial NADH dehydrogenase and CYP2D6 genotypes in Lewy-body parkinsonism. Journal of neuroscience research. vol 44. issue 2. 1996-09-26. PMID:8723226. |
twenty-one parkinsonian brains with brain stem lewy-bodies and 77 control brains were genotyped at two mitochondrial loci previously implicated in the etiology of neurodegenerative disease. |
1996-09-26 |
2023-08-12 |
Not clear |
| N Tachibana, K Kimura, K Kitajima, T Nagamine, J Kimura, H Shibasak. REM sleep without atonia at early stage of sporadic olivopontocerebellar atrophy. Journal of the neurological sciences. vol 132. issue 1. 1996-01-19. PMID:8523027. |
rwa may be a clinically important finding as a sign of brainstem dysfunction at early stage of neurodegenerative diseases. |
1996-01-19 |
2023-08-12 |
Not clear |
| R Raininko, T Autti, S L Vanhanen, A Ylikoski, T Erkinjuntti, P Santavuor. The normal brain stem from infancy to old age. A morphometric MRI study. Neuroradiology. vol 36. issue 5. 1994-10-26. PMID:7936176. |
knowledge of the normal variation in size of the brain stem can be helpful in the investigation of neurodegenerative diseases. |
1994-10-26 |
2023-08-12 |
human |
| A H Sharpe, R Jaenisc. Retroviral spongiform degenerative disease produced by the murine neurotropic retrovirus Cas-Br-E. Developments in biological standardization. vol 80. 1994-02-03. PMID:8270115. |
the murine neurotropic retrovirus cas-br-e causes a non-inflammatory spongiform neurodegenerative disease involving the spinal cord, brainstem and cerebellum, manifest as a progressive, fatal lower motor neuron disease. |
1994-02-03 |
2023-08-12 |
mouse |
| R Van der Neut, W H Gispen, P R Bä. Serum from patients with amyotrophic lateral sclerosis induces the expression of B-50/GAP-43 and neurofilament in cultured rat fetal spinal neurons. Molecular and chemical neuropathology. vol 14. issue 3. 1992-01-03. PMID:1835579. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease affecting motor neurons in the spinal cord, brain stem, and cortex. |
1992-01-03 |
2023-08-11 |
rat |
| Y J Chen, T Kurokawa, A Mitsudome, T Hanai, O Narazaki, K Ued. Brainstem auditory evoked potentials in children with neurodegenerative diseases. European journal of pediatrics. vol 145. issue 6. 1987-03-30. PMID:2434332. |
brainstem auditory evoked potentials in children with neurodegenerative diseases. |
1987-03-30 |
2023-08-11 |
Not clear |