| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alex Iranzo, Pietro Luca Ratti, Jordi Casanova-Molla, Mónica Serradell, Isabel Vilaseca, Joan Santamari. Excessive muscle activity increases over time in idiopathic REM sleep behavior disorder. Sleep. vol 32. issue 9. 2009-10-16. PMID:19750919. |
patients with idiopathic rbd often develop a neurodegenerative disease, such as parkinson disease, over the years, suggesting progression of an underlying pathologic process in the brainstem. |
2009-10-16 |
2023-08-12 |
Not clear |
| Daniel Offen, Yael Barhum, Eldad Melamed, Norbert Embacher, Christoph Schindler, Gerhard Ransmay. Spinal cord mRNA profile in patients with ALS: comparison with transgenic mice expressing the human SOD-1 mutant. Journal of molecular neuroscience : MN. vol 38. issue 2. 2009-08-31. PMID:18651250. |
amyotrophic lateral sclerosis (als) is a progressive neurodegenerative disease characterized by loss of motor neurons in the cerebral cortex, brain stem, and spinal cord. |
2009-08-31 |
2023-08-12 |
mouse |
| b' L Tolosa, M Mir, G Olmos, J Llad\\xc3\\xb. Vascular endothelial growth factor protects motoneurons from serum deprivation-induced cell death through phosphatidylinositol 3-kinase-mediated p38 mitogen-activated protein kinase inhibition. Neuroscience. vol 158. issue 4. 2009-05-20. PMID:19041930.' |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease characterized by the selective degeneration and death of motoneurons in the spinal cord, brainstem and motor cortex which causes progressive muscle weakness and paralysis. |
2009-05-20 |
2023-08-12 |
rat |
| Lokesh C Wijesekera, P Nigel Leig. Amyotrophic lateral sclerosis. Orphanet journal of rare diseases. vol 4. 2009-05-05. PMID:19192301. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease characterised by progressive muscular paralysis reflecting degeneration of motor neurones in the primary motor cortex, corticospinal tracts, brainstem and spinal cord. |
2009-05-05 |
2023-08-12 |
Not clear |
| Irene Carunchio, Cristiana Mollinari, Massimo Pieri, Daniela Merlo, Cristina Zon. GAB(A) receptors present higher affinity and modified subunit composition in spinal motor neurons from a genetic model of amyotrophic lateral sclerosis. The European journal of neuroscience. vol 28. issue 7. 2009-01-30. PMID:18973555. |
amyotrophic lateral sclerosis is a neurodegenerative disease characterized by the selective degeneration of motor neurons in the spinal cord, brainstem and cerebral cortex. |
2009-01-30 |
2023-08-12 |
Not clear |
| Kazunori Tanaka, Yoshinori Okada, Takuya Kanno, Asako Otomo, Yoshiko Yanagisawa, Junko Shouguchi-Miyata, Etsuko Suga, Eri Kohiki, Kyuichiro Onoe, Hitoshi Osuga, Masashi Aoki, Shinji Hadano, Yasuto Itoyama, Joh-E Iked. A dopamine receptor antagonist L-745,870 suppresses microglia activation in spinal cord and mitigates the progression in ALS model mice. Experimental neurology. vol 211. issue 2. 2008-07-07. PMID:18423451. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease characterized by a selective loss of motor neurons in the motor cortex, brainstem, and spinal cord. |
2008-07-07 |
2023-08-12 |
mouse |
| Jeffrey P Greenfield, Angel Ayuso-Sacido, Theodore H Schwartz, Susan Pannullo, Mark Souweidane, Philip E Stieg, John A Boockva. Use of human neural tissue for the generation of progenitors. Neurosurgery. vol 62. issue 1. 2008-04-09. PMID:18300889. |
this nearly limitless resource holds promise for understanding the basic biology of normal brain stem cells and tscs, which will likely direct the next major shift in therapeutics for brain tumors, brain and spinal cord injury, and neurodegenerative disease. |
2008-04-09 |
2023-08-12 |
human |
| Keiichi Kadoyama, Hiroshi Funakoshi, Wakana Ohya, Toshikazu Nakamur. Hepatocyte growth factor (HGF) attenuates gliosis and motoneuronal degeneration in the brainstem motor nuclei of a transgenic mouse model of ALS. Neuroscience research. vol 59. issue 4. 2008-01-11. PMID:17935811. |
amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease characterized by progressive loss of brainstem and spinal motoneurons. |
2008-01-11 |
2023-08-12 |
mouse |
| Ezia Guatteo, Irene Carunchio, Massimo Pieri, Federica Albo, Nadia Canu, Nicola B Mercuri, Cristina Zon. Altered calcium homeostasis in motor neurons following AMPA receptor but not voltage-dependent calcium channels' activation in a genetic model of amyotrophic lateral sclerosis. Neurobiology of disease. vol 28. issue 1. 2007-12-12. PMID:17706428. |
amyotrophic lateral sclerosis (als) is a late-onset progressive neurodegenerative disease characterized by a substantial loss of motor neurons in the spinal cord, brain stem and motor cortex. |
2007-12-12 |
2023-08-12 |
mouse |
| Chengyun Zheng, Mattias K Sköld, Jian Li, Inger Nennesmo, Bengt Fadeel, Jan-Inge Hente. VEGF reduces astrogliosis and preserves neuromuscular junctions in ALS transgenic mice. Biochemical and biophysical research communications. vol 363. issue 4. 2007-12-06. PMID:17923114. |
amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease resulting from motor neuron loss in the spinal cord and brain stem. |
2007-12-06 |
2023-08-12 |
mouse |
| M Minnerop, K Specht, J Ruhlmann, N Schimke, M Abele, A Weyer, U Wüllner, T Klockgethe. Voxel-based morphometry and voxel-based relaxometry in multiple system atrophy-a comparison between clinical subtypes and correlations with clinical parameters. NeuroImage. vol 36. issue 4. 2007-10-18. PMID:17512219. |
multiple system atrophy (msa) is a neurodegenerative disease affecting basal ganglia, brainstem, cerebellum, and intermediolateral cell columns of the spinal cord. |
2007-10-18 |
2023-08-12 |
Not clear |
| Jia Wei Liu, Song Jiu Tian, Jean de Barry, Bang Lu. Panaxadiol glycosides that induce neuronal differentiation in neurosphere stem cells. Journal of natural products. vol 70. issue 8. 2007-10-04. PMID:17663584. |
these findings imply that 3 may be utilized as a pharmacological agent in studying the molecular regulation of neurogenesis of brain stem cells and, subsequently, for treatment of neurodegenerative diseases. |
2007-10-04 |
2023-08-12 |
Not clear |
| L Van den Bosc. [The causes and mechanism of selective motor neuron death in amyotrophic lateral sclerosis]. Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie. vol 68. issue 4. 2007-01-25. PMID:17214440. |
amyotrophic lateral sclerosis is a neurodegenerative disease characterized by the selective death of motor neurons in the motor cortex, brain stem and spinal cord. |
2007-01-25 |
2023-08-12 |
mouse |
| Cristina Zona, Massimo Pieri, Irene Carunchi. Voltage-dependent sodium channels in spinal cord motor neurons display rapid recovery from fast inactivation in a mouse model of amyotrophic lateral sclerosis. Journal of neurophysiology. vol 96. issue 6. 2007-01-17. PMID:16899637. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease characterized by a substantial loss of motor neurons in the spinal cord, brain stem, and motor cortex. |
2007-01-17 |
2023-08-12 |
mouse |
| Yeo Kyoung Oh, Ki Soon Shin, Shin Jung Kan. AIF translocates to the nucleus in the spinal motor neurons in a mouse model of ALS. Neuroscience letters. vol 406. issue 3. 2006-11-01. PMID:16916579. |
amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease characterized by selective loss of motor neurons in the brain stem and the spinal cords. |
2006-11-01 |
2023-08-12 |
mouse |
| Anna-Lena Ström, Lars Forsgren, Monica Holmber. A role for both wild-type and expanded ataxin-7 in transcriptional regulation. Neurobiology of disease. vol 20. issue 3. 2006-03-09. PMID:15936949. |
spinocerebellar ataxia type 7 (sca7) is a neurodegenerative disease primarily affecting the brainstem, retina and purkinje cells of the cerebellum. |
2006-03-09 |
2023-08-12 |
Not clear |
| Anna-Lena Ström, Lars Forsgren, Monica Holmber. Identification and characterization of Spinocerebellar Ataxia Type 7 (SCA7) isoform SCA7b in mice. Biochimica et biophysica acta. vol 1731. issue 3. 2006-02-03. PMID:16297465. |
spinocerebellar ataxia type 7 (sca7) is a neurodegenerative disease primarily affecting the cerebellum, brainstem and retina. |
2006-02-03 |
2023-08-12 |
mouse |
| Sandra M Klein, Soshana Behrstock, Jacalyn McHugh, Kristin Hoffmann, Kyle Wallace, Masatoshi Suzuki, Patrick Aebischer, Clive N Svendse. GDNF delivery using human neural progenitor cells in a rat model of ALS. Human gene therapy. vol 16. issue 4. 2005-08-23. PMID:15871682. |
amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease characterized by progressive loss of spinal cord, brainstem, and cortical motor neurons. |
2005-08-23 |
2023-08-12 |
human |
| Andreas J Fallgatter, Ann-Christine Ehlis, Thomas M Ringel, Martin J Herrman. Age effect on far field potentials from the brain stem after transcutaneous vagus nerve stimulation. International journal of psychophysiology : official journal of the International Organization of Psychophysiology. vol 56. issue 1. 2005-07-25. PMID:15725488. |
this is a prerequisite for testing this method in elderly patients with neurodegenerative diseases like alzheimer and parkinson disease as a noninvasive tool to detect an affection of the brainstem nuclei of the vagus nerve early in their course. |
2005-07-25 |
2023-08-12 |
human |
| Chengyun Zheng, Inger Nennesmo, Bengt Fadeel, Jan-Inge Hente. Vascular endothelial growth factor prolongs survival in a transgenic mouse model of ALS. Annals of neurology. vol 56. issue 4. 2004-12-02. PMID:15389897. |
amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease associated with the death of motor neurons in the spinal cord and brainstem. |
2004-12-02 |
2023-08-12 |
mouse |