| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Qin Yang, Zhi-bao Gu. Polymorphisms in protein disulfide isomerase are associated with sporadic amyotrophic lateral sclerosis in the Chinese Han population. The International journal of neuroscience. vol 126. issue 7. 2017-01-17. PMID:26000911. |
amyotrophic lateral sclerosis (als) is a fatal adult-onset neurodegenerative disease that targets the motor system; it is caused by the loss of motor neurons in the spinal cord, brain stem, and cerebral cortex. |
2017-01-17 |
2023-08-13 |
human |
| Lipin Liang, Tao Chen, Yan W. The electrophysiology of spinocerebellar ataxias. Neurophysiologie clinique = Clinical neurophysiology. vol 46. issue 1. 2016-12-13. PMID:26947625. |
spinocerebellar ataxias (scas) are a group of autosomal dominantly inherited neurodegenerative diseases, involving the cerebellum and the brainstem. |
2016-12-13 |
2023-08-13 |
Not clear |
| Gianina Toller, Babu Adhimoolam, Katherine P Rankin, Hans-Jürgen Huppertz, Martin Kurthen, Hennric Jokei. Right fronto-limbic atrophy is associated with reduced empathy in refractory unilateral mesial temporal lobe epilepsy. Neuropsychologia. vol 78. 2016-08-04. PMID:26363299. |
in line with previous evidence from patients with neurodegenerative disease and stroke, the present study suggests that empathy depends upon the integrity of right fronto-limbic and brainstem regions and highlights the importance of the right mesial temporal lobe and midbrain structures for human empathy. |
2016-08-04 |
2023-08-13 |
human |
| Jonathan M Van Dyke, Ivy M Smit-Oistad, Corey Macrander, Dan Krakora, Michael G Meyer, Masatoshi Suzuk. Macrophage-mediated inflammation and glial response in the skeletal muscle of a rat model of familial amyotrophic lateral sclerosis (ALS). Experimental neurology. vol 277. 2016-06-27. PMID:26775178. |
amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease characterized by progressive motor dysfunction and loss of large motor neurons in the spinal cord and brain stem. |
2016-06-27 |
2023-08-13 |
human |
| Emilie Audouard, Laura Van Hees, Valérie Suain, Zehra Yilmaz, Luc Poncelet, Karelle Leroy, Jean-Pierre Brio. Motor deficit in a tauopathy model is induced by disturbances of axonal transport leading to dying-back degeneration and denervation of neuromuscular junctions. The American journal of pathology. vol 185. issue 10. 2016-05-03. PMID:26272360. |
several neurodegenerative diseases are characterized by both cognitive and motor deficits associated with accumulation of tau aggregates in brain, brainstem, and spinal cord. |
2016-05-03 |
2023-08-13 |
mouse |
| P K Chattha, P E Greene, Ritesh A Ramdhan. Pseudobulbar laughter as a levodopa off phenomenon exacerbated by subthalamic deep brain stimulation. Journal of clinical movement disorders. vol 2. 2016-01-20. PMID:26788349. |
pseudobulbar affect is a common symptom in neurodegenerative diseases and can also result from lesions in cortical, subcortical and brainstem regions. |
2016-01-20 |
2023-08-13 |
Not clear |
| Stefania Marcuzzo, Silvia Bonanno, Dimos Kapetis, Claudia Barzago, Paola Cavalcante, Sara D'Alessandro, Renato Mantegazza, Pia Bernascon. Up-regulation of neural and cell cycle-related microRNAs in brain of amyotrophic lateral sclerosis mice at late disease stage. Molecular brain. vol 8. 2016-01-19. PMID:25626686. |
amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease characterized by selective motor neuron degeneration in motor cortex, brainstem and spinal cord. |
2016-01-19 |
2023-08-13 |
mouse |
| Anna Gajowiak, Agnieszka Styś, Rafał R Starzyński, Aleksandra Bednarz, Małgorzata Lenartowicz, Robert Staroń, Paweł Lipińsk. Mice Overexpressing Both Non-Mutated Human SOD1 and Mutated SOD1(G93A) Genes: A Competent Experimental Model for Studying Iron Metabolism in Amyotrophic Lateral Sclerosis. Frontiers in molecular neuroscience. vol 8. 2016-01-18. PMID:26778957. |
amyotrophic lateral sclerosis (als) is a progressive neurodegenerative disease characterized by degeneration and loss of motor neurons in the spinal cord, brainstem and motor cortex. |
2016-01-18 |
2023-08-13 |
mouse |
| Mariella Simon, Elodie M Richard, Xinjian Wang, Mohsin Shahzad, Vincent H Huang, Tanveer A Qaiser, Prasanth Potluri, Sarah E Mahl, Antonio Davila, Sabiha Nazli, Saege Hancock, Margret Yu, Jay Gargus, Richard Chang, Nada Al-Sheqaih, William G Newman, Jose Abdenur, Arnold Starr, Rashmi Hegde, Thomas Dorn, Anke Busch, Eddie Park, Jie Wu, Hagen Schwenzer, Adrian Flierl, Catherine Florentz, Marie Sissler, Shaheen N Khan, Ronghua Li, Min-Xin Guan, Thomas B Friedman, Doris K Wu, Vincent Procaccio, Sheikh Riazuddin, Douglas C Wallace, Zubair M Ahmed, Taosheng Huang, Saima Riazuddi. Mutations of human NARS2, encoding the mitochondrial asparaginyl-tRNA synthetase, cause nonsyndromic deafness and Leigh syndrome. PLoS genetics. vol 11. issue 3. 2015-12-28. PMID:25807530. |
a homozygous missense mutation ([c.637g>t; p.val213phe]) is the underlying cause of nonsyndromic hearing loss (dfnb94) and compound heterozygous mutations ([c.969t>a; p.tyr323*] + [c.1142a>g; p.asn381ser]) result in mitochondrial respiratory chain deficiency and leigh syndrome, which is a neurodegenerative disease characterized by symmetric, bilateral lesions in the basal ganglia, thalamus, and brain stem. |
2015-12-28 |
2023-08-13 |
human |
| b' Katarina Vrabec, Bla\\xc5\\xbe Koritnik, Lea Leonardis, Leja Dolenc-Gro\\xc5\\xa1elj, Janez Zidar, Bradley Smith, Caroline Vance, Christopher Shaw, Boris Rogelj, Damjan Glava\\xc4\\x8d, Metka Ravnik-Glava\\xc4\\x8. Genetic analysis of amyotrophic lateral sclerosis in the Slovenian population. Neurobiology of aging. vol 36. issue 3. 2015-11-24. PMID:25585530.' |
amyotrophic lateral sclerosis (als) is a complex fatal neurodegenerative disease characterized by progressive degeneration and loss of upper motor neurons in the cerebral cortex and lower motor neurons in brainstem and spinal cord. |
2015-11-24 |
2023-08-13 |
Not clear |
| Sarah C Hopp, Sarah E Royer, Heather M D'Angelo, Roxanne M Kaercher, David A Fisher, Gary L Wen. Differential neuroprotective and anti-inflammatory effects of L-type voltage dependent calcium channel and ryanodine receptor antagonists in the substantia nigra and locus coeruleus. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. vol 10. issue 1. 2015-11-12. PMID:25318607. |
neuroinflammation and degeneration of catecholaminergic brainstem nuclei occur early in neurodegenerative diseases such as alzheimer's disease and parkinson's disease. |
2015-11-12 |
2023-08-13 |
rat |
| Safa Al-Sarraj, Andrew King, Matt Cleveland, Pierre-François Pradat, Andrea Corse, Jeffrey D Rothstein, Peter Nigel Leigh, Bams Abila, Stewart Bates, Jens Wurthner, Vincent Meininge. Mitochondrial abnormalities and low grade inflammation are present in the skeletal muscle of a minority of patients with amyotrophic lateral sclerosis; an observational myopathology study. Acta neuropathologica communications. vol 2. 2015-10-26. PMID:25510661. |
amyotrophic lateral sclerosis (als) is a primary progressive neurodegenerative disease characterised by neuronal loss of lower motor neurons (in the spinal cord and brainstem) and/or upper motor neurons (in the motor cortex) and subsequent denervation atrophy of skeletal muscle. |
2015-10-26 |
2023-08-13 |
Not clear |
| Chun Tak Kwok, Hsiang-Ya Wang, Alex G Morris, Bradley Smith, Christopher Shaw, Jackie de Belleroch. VCP mutations are not a major cause of familial amyotrophic lateral sclerosis in the UK. Journal of the neurological sciences. vol 349. issue 1-2. 2015-09-28. PMID:25618255. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease causing loss of motor neurons in the spinal cord, brain stem and cerebral cortex. |
2015-09-28 |
2023-08-13 |
Not clear |
| Kwang S Kim, Hong J Lee, Jin An, Yun B Kim, Jung Chan Ra, Inja Lim, Seung U Ki. Transplantation of human adipose tissue-derived stem cells delays clinical onset and prolongs life span in ALS mouse model. Cell transplantation. vol 23. issue 12. 2015-09-15. PMID:24070071. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease that selectively affects motor neurons in the cortex, brain stem, and spinal cord. |
2015-09-15 |
2023-08-12 |
mouse |
| U E Williams, E E Philip-Ephraim, S K Opara. Multidisciplinary Interventions in Motor Neuron Disease. Journal of neurodegenerative diseases. vol 2014. 2015-08-28. PMID:26317009. |
motor neuron disease is a neurodegenerative disease characterized by loss of upper motor neuron in the motor cortex and lower motor neurons in the brain stem and spinal cord. |
2015-08-28 |
2023-08-13 |
Not clear |
| Milija D Mijajlovic, Georgios Tsivgoulis, Nadezda Sterni. Transcranial brain parenchymal sonography in neurodegenerative and psychiatric diseases. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine. vol 33. issue 12. 2015-07-24. PMID:25425361. |
brain stem raphe hypoechogenicity or interruption has been shown to be highly prevalent in patients with unipolar depression as well as depression associated with certain neurodegenerative diseases. |
2015-07-24 |
2023-08-13 |
Not clear |
| H-Q Jiang, M Ren, H-Z Jiang, J Wang, J Zhang, X Yin, S-Y Wang, Y Qi, X-D Wang, H-L Fen. Guanabenz delays the onset of disease symptoms, extends lifespan, improves motor performance and attenuates motor neuron loss in the SOD1 G93A mouse model of amyotrophic lateral sclerosis. Neuroscience. vol 277. 2015-06-08. PMID:24699224. |
amyotrophic lateral sclerosis (als) is a relentlessly progressive neurodegenerative disease characterized by the loss of motor neurons in the motor cortex, brain stem and spinal cord. |
2015-06-08 |
2023-08-13 |
mouse |
| Hans-Georg König, Karen S Coughlan, Sinéad Kinsella, Bridget A Breen, Jochen H M Preh. The BCL-2 family protein Bid is critical for pro-inflammatory signaling in astrocytes. Neurobiology of disease. vol 70. 2015-04-21. PMID:24956542. |
amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease characterized by the loss of motoneurons in the spinal cord, brainstem and motor cortex. |
2015-04-21 |
2023-08-13 |
mouse |
| Gastone G Celesi. Hearing disorders in brainstem lesions. Handbook of clinical neurology. vol 129. 2015-04-17. PMID:25726288. |
any disorder of the brainstem (e.g., neoplasms, vascular disorders, infections, trauma, demyelinating disorders, neurodegenerative diseases, malformations) that involves the auditory pathways and/or centers may produce hearing abnormalities. |
2015-04-17 |
2023-08-13 |
Not clear |
| Renzo Mancuso, Jaume del Valle, Laura Modol, Anna Martinez, Ana B Granado-Serrano, Omar Ramirez-Núñez, Mercé Pallás, Manel Portero-Otin, Rosario Osta, Xavier Navarr. Resveratrol improves motoneuron function and extends survival in SOD1(G93A) ALS mice. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 11. issue 2. 2014-12-16. PMID:24414863. |
amyotrophic lateral sclerosis (als) is an adult onset neurodegenerative disease that causes progressive paralysis and death due to degeneration of motoneurons in spinal cord, brainstem and motor cortex. |
2014-12-16 |
2023-08-12 |
mouse |