| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alida Spalloni, Michele Nutini, Patrizia Longon. Role of the N-methyl-d-aspartate receptors complex in amyotrophic lateral sclerosis. Biochimica et biophysica acta. vol 1832. issue 2. 2013-03-14. PMID:23200922. |
amyotrophic lateral sclerosis (als) is an adult onset neurodegenerative disease pathologically characterized by the massive loss of motor neurons in the spinal cord, brain stem and cerebral cortex. |
2013-03-14 |
2023-08-12 |
Not clear |
| Antonio José da Rocha, Antonio Carlos Martins Maia Júnio. Is magnetic resonance imaging a plausible biomarker for upper motor neuron degeneration in amyotrophic lateral sclerosis/primary lateral sclerosis or merely a useful paraclinical tool to exclude mimic syndromes? A critical review of imaging applicability in clinical routine. Arquivos de neuro-psiquiatria. vol 70. issue 7. 2013-02-01. PMID:22836461. |
amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease that affects motor neurons in the cerebral cortex, brainstem, and spinal cord, brain regions in which conventional magnetic resonance imaging is often uninformative. |
2013-02-01 |
2023-08-12 |
Not clear |
| Balajee R Somalinga, Cameron E Day, Shuguang Wei, Michael G Roth, Philip J Thoma. TDP-43 identified from a genome wide RNAi screen for SOD1 regulators. PloS one. vol 7. issue 4. 2012-09-17. PMID:22563406. |
amyotrophic lateral sclerosis (als) is a late-onset, progressive neurodegenerative disease affecting motor neurons in the brain stem and spinal cord leading to loss of voluntary muscular function and ultimately, death due to respiratory failure. |
2012-09-17 |
2023-08-12 |
Not clear |
| b' Mauro Cozzolino, Maria Teresa Carr\\xc3\\xa. Mitochondrial dysfunction in ALS. Progress in neurobiology. vol 97. issue 2. 2012-09-14. PMID:21827820.' |
in the present article, we review the many facets of mitochondrial dysfunction in amyotrophic lateral sclerosis (als), a fatal neurodegenerative disease due to loss of upper motor neurons in cerebral cortex and lower motor neurons in brainstem and spinal cord. |
2012-09-14 |
2023-08-12 |
Not clear |
| Michael Gold, Stefan Lorenzl, Alistair J Stewart, Bruce H Morimoto, David R Williams, Illana Goze. Critical appraisal of the role of davunetide in the treatment of progressive supranuclear palsy. Neuropsychiatric disease and treatment. vol 8. 2012-03-20. PMID:22347799. |
progressive supranuclear palsy (psp) is a rare neurodegenerative disease characterized by the accumulation of tau protein aggregates in the basal ganglia, brainstem and cerebral cortex leading to rapid disease progression and death. |
2012-03-20 |
2023-08-12 |
Not clear |
| Caroline Kizilyaprak, Danièle Spehner, Didier Devys, Patrick Schult. The linker histone H1C contributes to the SCA7 nuclear phenotype. Nucleus (Austin, Tex.). vol 2. issue 5. 2012-03-06. PMID:21970987. |
spinocerebellar ataxia type 7 (sca7) is a neurodegenerative disease caused by a polyglutamine expansion in ataxin-7, a subunit of the saga coactivator, which leads to progressive neuronal dysfunction and cell death in cerebellum, brainstem and retina. |
2012-03-06 |
2023-08-12 |
mouse |
| Lea Tenenholz Grinberg, Udo Rueb, Helmut Heinse. Brainstem: neglected locus in neurodegenerative diseases. Frontiers in neurology. vol 2. 2011-11-10. PMID:21808630. |
brainstem: neglected locus in neurodegenerative diseases. |
2011-11-10 |
2023-08-12 |
Not clear |
| Orlando Graziani Povoas Barsottini, André Carvalho Felício, Camila Catherine Henriques de Aquino, José Luiz Pedros. Progressive supranuclear palsy: new concepts. Arquivos de neuro-psiquiatria. vol 68. issue 6. 2011-09-28. PMID:21243256. |
progressive supranuclear palsy (psp) is a distinctive form of neurodegenerative disease which affects the brainstem and basal ganglia. |
2011-09-28 |
2023-08-12 |
Not clear |
| Renzo Mancuso, Eva Santos-Nogueira, Rosario Osta, Xavier Navarr. Electrophysiological analysis of a murine model of motoneuron disease. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. vol 122. issue 8. 2011-09-09. PMID:21354365. |
amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease characterized by loss of motoneurons of the primary motor cortex, the brainstem and the spinal cord, for which there are not effective treatments. |
2011-09-09 |
2023-08-12 |
mouse |
| Ewa Naganska, Ewa Matyj. Amyotrophic lateral sclerosis - looking for pathogenesis and effective therapy. Folia neuropathologica. vol 49. issue 1. 2011-07-20. PMID:21455838. |
amyotrophic lateral sclerosis (als) is a progressive neurodegenerative disease characterized by loss of motor neurons in the spinal cord, brain stem and motor cortex which dramatically reduces life expectancy. |
2011-07-20 |
2023-08-12 |
Not clear |
| James E Davison, Nigel P Davies, Martin W English, Sunny Philip, Lesley K R MacPherson, Paul Gissen, Andrew C Pee. Magnetic resonance spectroscopy in the diagnostic evaluation of brainstem lesions in Alexander disease. Journal of child neurology. vol 26. issue 3. 2011-07-01. PMID:21270471. |
alexander disease is a progressive neurodegenerative disease, which can present with brainstem lesions with imaging characteristics similar to multifocal low-grade glioma, thus presenting a diagnostic dilemma. |
2011-07-01 |
2023-08-12 |
Not clear |
| Udo Rüb, Joanna C Jen, Heiko Braak, Thomas Delle. Functional neuroanatomy of the human premotor oculomotor brainstem nuclei: insights from postmortem and advanced in vivo imaging studies. Experimental brain research. vol 187. issue 2. 2011-05-25. PMID:18385989. |
data from control brains and from patients suffering from spinocerebellar ataxia type 3, a neurodegenerative disease that severely impairs oculomotor function are discussed and recommendations for the identification of human premotor oculomotor brainstem nuclei in post-mortem studies are given. |
2011-05-25 |
2023-08-12 |
human |
| Masaya Oda, Yuishin Izumi, Ryuji Kaj. [Gene mutations in familial amyotrophic lateral sclerosis]. Brain and nerve = Shinkei kenkyu no shinpo. vol 63. issue 2. 2011-05-05. PMID:21301041. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease characterized by progressive muscle weakness that reflects degeneration of motor neurons in the primary motor cortex, corticospinal tracts, brainstem, and spinal cord. |
2011-05-05 |
2023-08-12 |
Not clear |
| James C Dodge, Christopher M Treleaven, Jonathan A Fidler, Mark Hester, Amanda Haidet, Chalonda Handy, Meghan Rao, Amy Eagle, Jennifer C Matthews, Tatyana V Taksir, Seng H Cheng, Lamya S Shihabuddin, Brian K Kaspa. AAV4-mediated expression of IGF-1 and VEGF within cellular components of the ventricular system improves survival outcome in familial ALS mice. Molecular therapy : the journal of the American Society of Gene Therapy. vol 18. issue 12. 2011-04-18. PMID:20859261. |
amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease characterized by motor neuron cell death in the cortex, brainstem, and spinal cord. |
2011-04-18 |
2023-08-12 |
mouse |
| Martina Minnerop, Eileen Lüders, Karsten Specht, Jürgen Ruhlmann, Nicole Schimke, Paul M Thompson, Yi Y Chou, Arthur W Toga, Michael Abele, Ullrich Wüllner, Thomas Klockgethe. Callosal tissue loss in multiple system atrophy--a one-year follow-up study. Movement disorders : official journal of the Movement Disorder Society. vol 25. issue 15. 2011-02-25. PMID:20623690. |
multiple system atrophy (msa) is a neurodegenerative disease not only affecting the basal ganglia, brainstem, cerebellum, and intermediolateral cell columns of the spinal cord but also the cerebral cortex. |
2011-02-25 |
2023-08-12 |
Not clear |
| S Schmalbach, S Petr. Histone deacetylation and motor neuron degeneration. CNS & neurological disorders drug targets. vol 9. issue 3. 2010-12-21. PMID:20406183. |
amyotrophic lateral sclerosis (als) is a devastating neurodegenerative disease with progressive muscular wasting and paralysis due to loss of motor neurons in the primary motor cortex, brainstem and spinal cord. |
2010-12-21 |
2023-08-12 |
Not clear |
| Scoty M Hearst, Mariper E Lopez, Qingmei Shao, Yong Liu, Parminder J S Vi. Dopamine D2 receptor signaling modulates mutant ataxin-1 S776 phosphorylation and aggregation. Journal of neurochemistry. vol 114. issue 3. 2010-10-06. PMID:20477910. |
spinocerebellar ataxia 1 (sca1) is a dominantly inherited neurodegenerative disease associated with progressive ataxia resulting from the loss of cerebellar purkinje cells (pcs) and neurons in the brainstem. |
2010-10-06 |
2023-08-12 |
mouse |
| Anhar Hassan, Jennifer L Whitwell, Bradley F Boeve, Clifford R Jack, Joseph E Parisi, Dennis W Dickson, Keith A Joseph. Symmetric corticobasal degeneration (S-CBD). Parkinsonism & related disorders. vol 16. issue 3. 2010-05-24. PMID:20018548. |
corticobasal degeneration (cbd) is a neurodegenerative disease characterized pathologically by neuronal loss, gliosis and tau deposition in neocortex, basal ganglia and brainstem. |
2010-05-24 |
2023-08-12 |
Not clear |
| Thomas Polak, Falko Markulin, Ann-Christine Ehlis, Julia B M Langer, Thomas M Ringel, Andreas J Fallgatte. Far field potentials from brain stem after transcutaneous vagus nerve stimulation: optimization of stimulation and recording parameters. Journal of neural transmission (Vienna, Austria : 1996). vol 116. issue 10. 2010-01-14. PMID:19728032. |
the reason for focussing on brain stem evoked potentials is that recent work has accumulated evidence for this area being involved in early phases of neurodegenerative diseases such as alzheimer's disease and parkinson's disease. |
2010-01-14 |
2023-08-12 |
human |
| Rubén Fernández-Santiago, Sabine Hoenig, Peter Lichtner, Anne-Dorte Sperfeld, Manu Sharma, Daniela Berg, Oliver Weichenrieder, Thomas Illig, Katharina Eger, Thomas Meyer, Johanna Anneser, Christoph Münch, Stephan Zierz, Thomas Gasser, Albert Ludolp. Identification of novel Angiogenin (ANG) gene missense variants in German patients with amyotrophic lateral sclerosis. Journal of neurology. vol 256. issue 8. 2009-11-13. PMID:19363631. |
amyotrophic lateral sclerosis (als) is a fatal progressive neurodegenerative disease characterized by the selective death of motor neurons in the motor cortex, brain stem and spinal cord. |
2009-11-13 |
2023-08-12 |
Not clear |