| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Cong, R Liu, J Hou, X Wang, H Jiang, J Wan. Effects of trastuzumab on the proliferation and apoptosis of ovarian cancer cells. Neoplasma. vol 66. issue 2. 2019-08-15. PMID:30509111. |
proliferation and apoptosis of skov3 cells were then measured by mts assay and flow cytometry and cleaved caspase-3 expression was detected by western blot. |
2019-08-15 |
2023-08-13 |
human |
| Khadijeh Bijangi-Vishehsaraei, M Reza Saadatzadeh, Haiyan Wang, Angie Nguyen, Malgorzata M Kamocka, Wenjing Cai, Aaron A Cohen-Gadol, Stacey L Halum, Jann N Sarkaria, Karen E Pollok, Ahmad R Saf. Sulforaphane suppresses the growth of glioblastoma cells, glioblastoma stem cell-like spheroids, and tumor xenografts through multiple cell signaling pathways. Journal of neurosurgery. vol 127. issue 6. 2019-08-14. PMID:28059653. |
methods the inhibitory effects of sfn on established cell lines, early primary cultures, cd133-positive gscs, gsc-derived spheroids, and gbm xenografts were evaluated using various methods, including gsc isolation and the sphere-forming assay, analysis of reactive oxygen species (ros) and apoptosis, cell growth inhibition assay, comet assays for assessing sfn-triggered dna damage, confocal microscopy, western blot analysis, and the determination of in vivo efficacy as assessed in human gbm xenograft models. |
2019-08-14 |
2023-08-13 |
human |
| Jingjing Zhang, Changlei Cui, Yanhui Li, Haiyang X. Inhibition of GSK-3beta Signaling Pathway Rescues Ketamine-Induced Neurotoxicity in Neural Stem Cell-Derived Neurons. Neuromolecular medicine. vol 20. issue 1. 2019-08-13. PMID:29218434. |
keta (50 μm)-induced neurotoxicity in cultured nscns was monitored by apoptosis, immunohistochemical and western blot assays, respectively. |
2019-08-13 |
2023-08-13 |
Not clear |
| Jie Li, Dan Feng, Cuixia Gao, Yingyi Zhang, Jing Xu, Meihong Wu, Xianbao Zha. Isoforms S and L of MRPL33 from alternative splicing have isoform‑specific roles in the chemoresponse to epirubicin in gastric cancer cells via the PI3K/AKT signaling pathway. International journal of oncology. vol 54. issue 5. 2019-08-13. PMID:30816492. |
furthermore, western blot analysis indicated that mrpl33‑s promoted the chemoresponse to epirubicin by deactivating pi3k/akt/creb signaling and inducing apoptosis, while mrpl33‑l had the opposite effects. |
2019-08-13 |
2023-08-13 |
Not clear |
| Kotaro Makita, Hiroyuki Hara, Emiko Sano, Yutaka Okamoto, Yushi Ochiai, Tomonori Harada, Takuya Ueda, Tomohiro Nakayama, Shin Aizawa, Atsuo Yoshin. Interferon-β sensitizes human malignant melanoma cells to temozolomide-induced apoptosis and autophagy. International journal of oncology. vol 54. issue 5. 2019-08-13. PMID:30864696. |
the expression of proteins involved in the cell cycle, apoptosis and autophagy was evaluated by western blot analysis. |
2019-08-13 |
2023-08-13 |
human |
| Jun Liu, Qingqing Li, Xiaoxin Li, Zhenzhen Qiu, Andrew Li, Wenhan Liang, Huangyao Chen, Xiangsheng Cai, Xinglu Chen, Xinyue Duan, Jingjing Li, Wangsheng Wu, Mingyu Xu, Yingying Mao, Huiying Chen, Jinlong Li, Weiwang Gu, Hongwei L. Zika Virus Envelope Protein induces G2/M Cell Cycle Arrest and Apoptosis via an Intrinsic Cell Death Signaling Pathway in Neuroendocrine PC12 Cells. International journal of biological sciences. vol 14. issue 9. 2019-08-12. PMID:29989100. |
flow cytometry and western blot analysis showed that the apoptosis was associated with up-regulation of both p53 and p21 |
2019-08-12 |
2023-08-13 |
Not clear |
| Wei Wei, Xiao-Bing Lan, Ning Liu, Jia-Mei Yang, Juan Du, Lin Ma, Wen-Jin Zhang, Jian-Guo Niu, Tao Sun, Jian-Qiang Y. Echinacoside Alleviates Hypoxic-Ischemic Brain Injury in Neonatal Rat by Enhancing Antioxidant Capacity and Inhibiting Apoptosis. Neurochemical research. vol 44. issue 7. 2019-08-12. PMID:30911982. |
tunel staining and western blot analysis was performed to respectively estimate the extent of brain cell apoptosis and the expression level of the apoptosis-related proteins caspase-3, bax, and bcl-2. |
2019-08-12 |
2023-08-13 |
rat |
| Lingrong Zeng, Yu Sun, Xiaolei Li, Jingcheng Wang, Lianqi Ya. 10‑Hydroxycamptothecin induces apoptosis in human fibroblasts by regulating miRNA‑23b‑3p expression. Molecular medicine reports. vol 19. issue 4. 2019-08-01. PMID:30720099. |
the effects of hcpt and mir‑23b‑3p on fibroblast apoptosis were assessed using terminal deoxynucleotidyl‑transferase‑mediated dutp nick‑end labeling, flow cytometry and western blot analysis. |
2019-08-01 |
2023-08-13 |
human |
| Dingyun Li, Tao Zhang, Jiajun Lai, Jian Zhang, Ting Wang, Yafei Ling, Shengquan He, Zhiwei H. MicroRNA‑25/ATXN3 interaction regulates human colon cancer cell growth and migration. Molecular medicine reports. vol 19. issue 5. 2019-08-01. PMID:30942397. |
cell viability and cell migration were analyzed using mtt and wound healing assays, respectively, apoptosis was analyzed using flow cytometry, and western blot analysis was conducted to determine the protein expression of ataxin‑3 (atxn3), apoptosis regulator bax (bax) and cyclin d1. |
2019-08-01 |
2023-08-13 |
human |
| Jie Zheng, Su Min, Bin Hu, Qin Liu, Yunqiang Wa. Nrdp1 is involved in hippocampus apoptosis in cardiopulmonary bypass-induced cognitive dysfunction via the regulation of ErbB3 protein levels. International journal of molecular medicine. vol 43. issue 4. 2019-07-30. PMID:30720051. |
apoptosis in the hippocampus regions were measured using a terminal deoxynucleotidyl‑transferase‑mediated dutp nick end labelling assay, the viability and apoptosis level of the cells were measured via an mtt assay and flow cytometry, respectively, and the expression levels of nrdp1, erb‑b2 receptor tyrosine kinase 3 (erbb3), phosphorylated‑protein kinase b (p‑akt) and cleaved (c‑) caspase‑3 were detected using western blot analysis. |
2019-07-30 |
2023-08-13 |
rat |
| Guiping Luo, Zhao Jian, Yun Zhu, Yu Zhu, Baicheng Chen, Ruiyan Ma, Fuqin Tang, Yingbin Xia. Sirt1 promotes autophagy and inhibits apoptosis to protect cardiomyocytes from hypoxic stress. International journal of molecular medicine. vol 43. issue 5. 2019-07-30. PMID:30864731. |
the data from the western blot analysis revealed that sirt1 promoted autophagic flux and reduced apoptosis in hypoxic h9c2 cells. |
2019-07-30 |
2023-08-13 |
mouse |
| Chia-Cheng Su, Kun-Lin Hsieh, Po-Len Liu, Hsin-Chih Yeh, Shu-Pin Huang, Shih-Hua Fang, Wei-Chung Cheng, Kuan-Hua Huang, Fang-Yen Chiu, I-Ling Lin, Ming-Yii Huang, Chia-Yang L. AICAR Induces Apoptosis and Inhibits Migration and Invasion in Prostate Cancer Cells Through an AMPK/mTOR-Dependent Pathway. International journal of molecular sciences. vol 20. issue 7. 2019-07-30. PMID:30987073. |
cell growth was performed by mtt assay and soft agar assay; cell apoptosis was examined by annexin v/propidium iodide (pi) staining and poly adp ribose polymerase (parp) cleavage western blot, while cell migration and invasion were evaluated by wound-healing assay and transwell assay respectively. |
2019-07-30 |
2023-08-13 |
Not clear |
| Michiharu Yoshida, Hiroyuki Kobayashi, Shunsuke Terasaka, Shogo Endo, Shigeru Yamaguchi, Hiroaki Motegi, Rachmilevitch Itay, Shuji Suzuki, Omer Brokman, Yeruham Shapira, Kenji Moriyama, Yumiko Kawase, Toshiaki Akahane, Yasutaka Kato, Hajime Kamada, Kiyohiro Houki. Sonodynamic Therapy for Malignant Glioma Using 220-kHz Transcranial Magnetic Resonance Imaging-Guided Focused Ultrasound and 5-Aminolevulinic acid. Ultrasound in medicine & biology. vol 45. issue 2. 2019-07-29. PMID:30522817. |
f98 cells were irradiated with focused ultrasound (fus) (4000 j, 20 w, 240 s, 100% duty cycle, target medium temperature <40°c) after treatment with 200 µg/ml 5-ala, and cell viability and apoptosis were evaluated with the water-soluble tetrazolium-1 assay, triple fluorescent staining and western blot analysis 20 h later. |
2019-07-29 |
2023-08-13 |
Not clear |
| Xinxin Liu, Fei Liu, Shuo Zhao, Bin Guo, Peixue Ling, Guanying Han, Zan Cu. Purification of an acidic polysaccharide from Suaeda salsa plant and its anti-tumor activity by activating mitochondrial pathway in MCF-7 cells. Carbohydrate polymers. vol 215. 2019-07-29. PMID:30981376. |
the data from the western blot showed an increase in the levels of bax, cytochrome c (cyto-c), caspase-3 and caspase-9 and a decrease in the level of bcl-2 further demonstrated that ssp2-2 could induce apoptosis via a mitochondrial pathway. |
2019-07-29 |
2023-08-13 |
Not clear |
| Ping Sun, Jun-Bo Yin, Li-Hua Liu, Jian Guo, Sheng-Hai Wang, Chun-Hui Qu, Chun-Xia Wan. Protective role of Dihydromyricetin in Alzheimer's disease rat model associated with activating AMPK/SIRT1 signaling pathway. Bioscience reports. vol 39. issue 1. 2019-07-26. PMID:30498091. |
then, the inflammatory cytokines expressions were determined by radioimmunoassay while expressions of ampk/sirt1 pathway-related proteins by western blot; and the apoptosis of hippocampal cells was detected by tdt-mediated dutp nick end labeling assay. |
2019-07-26 |
2023-08-13 |
rat |
| Leng-Xin Duan, Yang Gao, Xin-Fang Wu, Ke-Ke Qiu, Jian-Gang Wan. [Protective effect of earthworm active ingredients against endoplasmic reticulum stress induced L-02 hepatocyte apoptosis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 43. issue 14. 2019-07-23. PMID:30111057. |
the cell viability was measured with cck-8, the apoptosis of l-02 cells was detected by flow cytometry, and the relevant protein and mrna expressions were detected by western blot and qpcr. |
2019-07-23 |
2023-08-13 |
Not clear |
| Min Zhang, Yuehou Zhang, Jun Ding, Xiaohong Li, Chengyu Zang, Siyuan Yin, Jiaxu Ma, Yibing Wang, Yongqian Ca. The role of TrkA in the promoting wounding-healing effect of CD271 on epidermal stem cells. Archives of dermatological research. vol 310. issue 9. 2019-07-22. PMID:30209580. |
the biological characteristics of escs and their proliferation and apoptosis were detected using immunohistochemistry and western blot. |
2019-07-22 |
2023-08-13 |
mouse |
| Hong-Yan Li, Shen Yang, Jing-Chun Li, Jian-Xun Fen. Galectin 3 inhibition attenuates renal injury progression in cisplatin-induced nephrotoxicity. Bioscience reports. vol 38. issue 6. 2019-07-22. PMID:30455396. |
mcp-treated mice also demonstrated decreased renal fibrosis and apoptosis, as revealed by masson trichrome staining and western blot analysis of cleaved caspase-3. |
2019-07-22 |
2023-08-13 |
mouse |
| Feng Xu, Qi Li, Zhiyu Wang, Xiangming Ca. Sinomenine inhibits proliferation, migration, invasion and promotes apoptosis of prostate cancer cells by regulation of miR-23a. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 112. 2019-07-22. PMID:30784907. |
the related factors of cell cycle, apoptosis, metastasis and pi3k/akt and jak/stat signal pathways were measured by western blot. |
2019-07-22 |
2023-08-13 |
Not clear |
| Yanhua Chang, Ruifang Kon. Ganoderic acid A alleviates hypoxia-induced apoptosis, autophagy, and inflammation in rat neural stem cells through the PI3K/AKT/mTOR pathways. Phytotherapy research : PTR. vol 33. issue 5. 2019-07-22. PMID:30838711. |
proteins related to apoptosis, autophagy, and the pi3k/akt/mtor pathways were evaluated by western blot analysis. |
2019-07-22 |
2023-08-13 |
rat |