| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lijiang Wang, Liyue Wang, Xiaoxia Zhou, Guoran Ruan, Guangyong Yan. Qishen Yiqi Dropping Pills Ameliorates Doxorubicin-induced Cardiotoxicity in Mice via Enhancement of Cardiac Angiogenesis. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2019-07-19. PMID:30943187. |
moreover, tunel staining and western blot analysis of bax protein, bcl-2 protein, and cleaved caspase-3 protein expression levels were conducted to explore whether qydp exerted effect on cardiac apoptosis. |
2019-07-19 |
2023-08-13 |
mouse |
| Biao Cai, Shu Ye, Yan Wang, Ting-Ting Wang, Liang Wang, Ai-Juan Jiang, Zheng-Qing Fang, Guo-Ming Shen, Dao-Jun Xi. [Effects of Huangpu Tongqiao capsule on apoptosis of Alzheimer's disease cell model]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 43. issue 11. 2019-07-18. PMID:29945394. |
after primary cultured hippocampal neurons ad cell model was induced by aβ₂₅₋₃₅, cell survival rate was detected by mtt, cell apoptosis rate was assayed by flow cytometry, and protein expressions of bax, cyt c and caspase-3 were determined by western blot analysis. |
2019-07-18 |
2023-08-13 |
Not clear |
| Alyssa Cobbs, Xiaoming Chen, Yuanyuan Zhang, Jasmine George, Ming-Bo Huang, Vincent Bond, Winston Thompson, Xueying Zha. Saturated fatty acid stimulates production of extracellular vesicles by renal tubular epithelial cells. Molecular and cellular biochemistry. vol 458. issue 1-2. 2019-07-18. PMID:30993495. |
in nrk-52e cells, pa-enhanced ev release was associated with an induction of cell apoptosis reflected by an increase in cleaved caspase-3 protein by western blot and annexin v positive cells analyzed by flow cytometry. |
2019-07-18 |
2023-08-13 |
human |
| Qiang Chu, Yiying Zhao, Xuer Shi, Wen Han, Yanzhen Zhang, Xiaodong Zheng, Jing Zh. In vivo-like 3-D model for sodium nitrite- and acrylamide-induced hepatotoxicity tests utilizing HepG2 cells entrapped in micro-hollow fibers. Scientific reports. vol 7. issue 1. 2019-07-17. PMID:29093461. |
furthermore, western blot analysis of apoptosis pathways also supported the argument. |
2019-07-17 |
2023-08-13 |
Not clear |
| Chun-Miao Luo, Jun Feng, Jing Zhang, Chao Gao, Ji-Yu Cao, Gao-Liang Zhou, Yong-Jing Jiang, Xiao-Qing Jin, Meng-Si Yang, Jian-Yuan Pan, Ai-Ling Wan. 1,25-Vitamin D3 protects against cooking oil fumes-derived PM2.5-induced cell damage through its anti-inflammatory effects in cardiomyocytes. Ecotoxicology and environmental safety. vol 179. 2019-07-16. PMID:31054378. |
cell viability was measured using cck-8 assay, and cell apoptosis was analyzed by flow cytometry, qrt-pcr and western blot in cultured rat neonatal cardiomyocytes treated with 1,25-vitamin d3 and cofs-derived pm2.5. |
2019-07-16 |
2023-08-13 |
rat |
| Chang Min Lee, Jongsung Lee, Myeong Jin Nam, Youn Soo Choi, See-Hyoung Par. Tomentosin Displays Anti-Carcinogenic Effect in Human Osteosarcoma MG-63 Cells via the Induction of Intracellular Reactive Oxygen Species. International journal of molecular sciences. vol 20. issue 6. 2019-07-09. PMID:30917517. |
after treatment with tomentosin, mg-63 cells were analyzed using the mtt assay, colony formation assay, cell counting assay, wound healing assay, boyden chamber assay, zymography assay, cell cycle analysis, fitc annexin v apoptosis assay, terminal deoxynucleotidyl transferase dutp nick end labeling assay, western blot analysis, and ros detection analysis. |
2019-07-09 |
2023-08-13 |
human |
| Xinwang Ying, Wenzhan Tu, Sisi Li, Qiaoyun Wu, Xiaolong Chen, Ye Zhou, Jie Hu, Guanhu Yang, Songhe Jian. Hyperbaric oxygen therapy reduces apoptosis and dendritic/synaptic degeneration via the BDNF/TrkB signaling pathways in SCI rats. Life sciences. vol 229. 2019-07-05. PMID:31108095. |
changes in neurological deficit, neuronal morphology, apoptosis, protein expression and dendrite/synapse were examined by basso-beattie-bresnahan (bbb) locomotor rating scale, hematoxylin-eosin (he) and nissl staining, tunel staining, rt-pcr, western blot, immunofluorescence and golgi-cox staining. |
2019-07-05 |
2023-08-13 |
rat |
| Xingyu Zhao, Xiaoxing Song, Jierui Zhao, Wenhe Zhu, Jiancheng Hou, Yanchun Wang, Wei Zhan. Juglone Inhibits Proliferation of HPV-Positive Cervical Cancer Cells Specifically. Biological & pharmaceutical bulletin. vol 42. issue 3. 2019-07-03. PMID:30606896. |
western blot expressed the influence mechanism that it affected the b-cell lymphoma 2 (bcl-2) family and later activated the caspase-depended apoptosis way. |
2019-07-03 |
2023-08-13 |
human |
| Yuxi Chen, Hongjun Chen, Hui Xie, Shaohui Yuan, Chuanbo Gao, Lei Yu, Zhenggang B. Non‑covalent proteasome inhibitor PI‑1840 induces apoptosis and autophagy in osteosarcoma cells. Oncology reports. vol 41. issue 5. 2019-07-03. PMID:30864717. |
the extent of cell apoptosis and autophagy were assessed by fcm, western blot analysis [of the apoptosis‑associated proteins, microtubule‑associated protein 1 light chain 3 α (lc3) and beclin1], and mrfp‑gfp‑lc3 adenovirus transfection assay. |
2019-07-03 |
2023-08-13 |
Not clear |
| Jiping Gao, Yu Wang, Guoqiang Xu, Jianing Wei, Kai Chang, Xiaolin Tian, Maolin Liu, Xiaoyan Yan, Meijun Huo, Guohua Son. Selenium attenuates apoptosis and p-AMPK expressions in fluoride-induced NRK-52E cells. Environmental science and pollution research international. vol 26. issue 15. 2019-07-02. PMID:30949948. |
at present, in this study, the normal rat kidney cell (nrk-52e) was used to investigate the potentially protective mechanism of se against naf-induced apoptosis, by using the methods of pathology, colorimetric 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay, flow cytometry, and western blot. |
2019-07-02 |
2023-08-13 |
rat |
| F F Li, D Sha, X Y Qin, C Z Li, B Li. Alpha1,2-fucosyl transferase gene, the key enzyme of Lewis y synthesis, promotes Taxol resistance of ovarian carcinoma through apoptosis-related proteins. Neoplasma. vol 65. issue 4. 2019-07-01. PMID:29940750. |
western blot was used to validate the protein expression level of fut1 and the apoptosis proteins. |
2019-07-01 |
2023-08-13 |
Not clear |
| F F Li, D Sha, X Y Qin, C Z Li, B Li. Alpha1,2-fucosyl transferase gene, the key enzyme of Lewis y synthesis, promotes Taxol resistance of ovarian carcinoma through apoptosis-related proteins. Neoplasma. vol 65. issue 4. 2019-07-01. PMID:29940750. |
caspase-3 activity and the apoptosis proteins were measured by colorimetry and western blot, respectively, to further compare the cell apoptosis ability in different groups. |
2019-07-01 |
2023-08-13 |
Not clear |
| L Tian, Z Z Tao, H P Ye, G Y Li, Z F Zhan, H W Tu. Over-expression of MEOX2 promotes apoptosis through inhibiting the PI3K/Akt pathway in laryngeal cancer cells. Neoplasma. vol 65. issue 5. 2019-07-01. PMID:29940775. |
real-time quantitative pcr (rt-qpcr) and western blot were used to detect mrna and protein levels of meox2 in laryngeal cancer tissues and cells (hep-2, tu212, amc-nh-8 and tu686 cells), and also apoptosis and phosphoinositide 3-kinase (pi3k)/protein kinase (akt) related factors in tu212 cells transfected with meox2. |
2019-07-01 |
2023-08-13 |
Not clear |
| H Y Yang, C P Huang, M M Cao, Y F Wang, Y Li. Long non-coding RNA CRNDE may be associated with poor prognosis by promoting proliferation and inhibiting apoptosis of cervical cancer cells through targeting PI3K/AKT. Neoplasma. vol 65. issue 6. 2019-07-01. PMID:30334449. |
loss-of-function assays revealed that crnde influences proliferation and apoptosis in cervical cancer cells, and western blot assays revealed that the pi3k/akt pathway was inactivated in response to crnde knockdown. |
2019-07-01 |
2023-08-13 |
human |
| T Jiang, J Chen, X B Huang, Y X Li, L Zhon. miR-451a induced apoptosis of Philadelphia chromosome-positive acute lymphoblastic leukemia cells by targeting IL-6R. Neoplasma. vol 65. issue 6. 2019-07-01. PMID:30334451. |
ph+ all cell line sup-b15 and ph- all cell line nalm-6 were treated with mir-451a mimic and inhibitor, respectively; proliferation rate was assessed by cck-8, apoptosis rate was tested by annexin/pi and the expression levels of bcl-xl, bax, cyclin d2 and c-myc were examined by qpcr and western blot (wb). |
2019-07-01 |
2023-08-13 |
Not clear |
| Haiqing Wang, Fang Wang, Xu Wang, Xuejun Wu, Fei Xu, Kunpeng Wang, Mingjie Xiao, Xing Ji. Friend or Foe: A Cancer Suppressor MicroRNA-34 Potentially Plays an Adverse Role in Vascular Diseases by Regulating Cell Apoptosis and Extracellular Matrix Degradation. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2019-07-01. PMID:30873956. |
the protein expression of apoptosis biomarkers was detected by western blot. |
2019-07-01 |
2023-08-13 |
human |
| Yingyuan Guo, Yanru Hao, Guofang Guan, Shuaishuai Ma, Zhiling Zhu, Fang Guo, Jie Ba. Mukonal Inhibits Cell Proliferation, Alters Mitochondrial Membrane Potential and Induces Apoptosis and Autophagy in Human CNE1 Nasopharyngeal Carcinoma Cells. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2019-07-01. PMID:30877718. |
fluorescence microscopy was used to detect reactive oxygen species (ros), mitochondrial membrane potential, and the release of cytochrome c. flow cytometry was used to examine changes in the cell cycle, electron microscopy examined cell autophagy, and western blot was performed to measure levels of proteins associated with autophagy and apoptosis. |
2019-07-01 |
2023-08-13 |
human |
| Bo Liao, Yingying Zhang, Quan Sun, Ping Jian. Vorinostat enhances the anticancer effect of oxaliplatin on hepatocellular carcinoma cells. Cancer medicine. vol 7. issue 1. 2019-06-24. PMID:29239146. |
cytotoxicity assay, tumorigenicity assay in vitro, cell cycle analysis, apoptosis analysis, western blot analysis, animal model study, immunohistochemistry, and quantitative pcr were performed. |
2019-06-24 |
2023-08-13 |
Not clear |
| Xiaogang Tang, Qiulong Ding, Chao Chen, Fei Chen, Xiyang Zhou, Chu Jie Hong, Wensheng Pa. Micheliolide inhibits gastric cancer growth Die Pharmazie. vol 74. issue 3. 2019-06-21. PMID:30961685. |
in this study, we detected the effects of mcl on gastric cancer cell proliferation and apoptosis by performing mtt, colony formation, tunel and western blot assays, and found that mcl inhibited gastric cancer cell proliferation and promoted apoptosis |
2019-06-21 |
2023-08-13 |
Not clear |
| Yu Hu, Ming-Chen Cai, Ling Wang, Ting-Huan Zhang, Zhong-Gang Luo, Gong-Wei Zhang, Fu-Yuan Zu. MiR-1246 is upregulated and regulates lung cell apoptosis during heat stress in feedlot cattle. Cell stress & chaperones. vol 23. issue 6. 2019-06-14. PMID:30105590. |
furthermore, by using bioinformatics analysis and luciferase reporter assays combined with qpcr and western blot, we found mir-1246 negatively regulated poly (c) binding protein 2 (pcbp2) and camp response element binding protein-like 2 (crebl2) mrna and protein levels through binding to the 3'-utr region (p < 0.05); further, it inhibited heat-induced apoptosis in lung cells. |
2019-06-14 |
2023-08-13 |
cattle |