| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marcella Flinterman, Joop Gäken, Farzin Farzaneh, Mahvash Tavassol. E1A-mediated suppression of EGFR expression and induction of apoptosis in head and neck squamous carcinoma cell lines. Oncogene. vol 22. issue 13. 2003-04-23. PMID:12673202. |
cell cycle and western blot analysis show e1a-mediated induction of apoptosis in all cell lines examined. |
2003-04-23 |
2023-08-12 |
human |
| Tetsuji Kakegawa, Hirohiko Ise, Nobuhiro Sugihara, Toshio Nikaido, Naoki Negishi, Toshihiro Akaike, Eiji Tanak. Soluble asialoglycoprotein receptors reflect the apoptosis of hepatocytes. Cell transplantation. vol 11. issue 5. 2003-04-18. PMID:12382666. |
in the present study, in order to investigate the correlation between apoptosis of hepatocytes and soluble agpr, mouse soluble agprs were detected using sds-page and western blot analysis was conducted using anti-extracellular mouse hepatic lectin-1 (ex-mhl-1) antiserum (polyclonal rabbit serum). |
2003-04-18 |
2023-08-12 |
human |
| W Keung Leung, Qiang Wu, Pauline M Hannam, Barry C McBride, Veli-Jukka Uitt. Treponema denticola may stimulate both epithelial proliferation and apoptosis through MAP kinase signal pathways. Journal of periodontal research. vol 37. issue 6. 2003-04-15. PMID:12472839. |
western blot analysis using map kinase phosphospecific antibodies showed that t. denticola strongly but transiently activated erk1 and erk2, signals mediating cell proliferation, and jnk and p38, kinases mediating apoptosis. |
2003-04-15 |
2023-08-12 |
human |
| Junichi Asakuma, Makoto Sumitomo, Takako Asano, Tomohiko Asano, Masamichi Hayakaw. Selective Akt inactivation and tumor necrosis actor-related apoptosis-inducing ligand sensitization of renal cancer cells by low concentrations of paclitaxel. Cancer research. vol 63. issue 6. 2003-04-11. PMID:12649200. |
apoptosis assays and western blot analyses revealed that apoptosis resistance to trail correlates well with the level of akt phosphorylation at ser 473 rather than protein expression levels of trail receptors, dr4 and dr5. |
2003-04-11 |
2023-08-12 |
human |
| Hiroki Ishikawa, Motoko Ikeda, Kenichi Yanagimoto, Cristiano A Felipe Alves, Yasuhiro Katou, Barbara A Laviña-Caoili, Michihiro Kobayash. Induction of apoptosis in an insect cell line, IPLB-Ld652Y, infected with nucleopolyhedroviruses. The Journal of general virology. vol 84. issue Pt 3. 2003-03-27. PMID:12604823. |
northern blot and immunoblot analyses revealed that hycunpv inhibitor of apoptosis 3 (iap3), which has been shown to function in sf9 cells, was expressed in hycunpv-infected ld652y cells at a level higher than or comparable with that in hycunpv-infected spim cells, which produced a high titre of progeny virions without any apoptotic response. |
2003-03-27 |
2023-08-12 |
Not clear |
| Mi-Hyeon Jang, Min-Chul Shin, Hye-Sook Shin, Khae-Hawn Kim, Heung-Jae Park, Ee-Hwa Kim, Chang-Ju Ki. Alcohol induces apoptosis in TM3 mouse Leydig cells via bax-dependent caspase-3 activation. European journal of pharmacology. vol 449. issue 1-2. 2003-03-20. PMID:12163104. |
to investigate whether ethanol induces apoptosis in leydig cells, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay, terminal deoxynuclotidyl transferase-mediated dutp nick end-labeling (tunel) assay, 4,6-diamidino-2-phenylindole (dapi) staining, dna fragmentation assay, caspase-3 enzyme assay, reverse transcription-polymerase chain reaction (rt-pcr) and western blot analysis were performed on tm3 mouse leydig cells. |
2003-03-20 |
2023-08-12 |
mouse |
| Debra W Taylor, Michael W Lamé, Lynn S Nakayama, H J Segall, Dennis W Wilso. Effects of monocrotaline pyrrole and thrombin on pulmonary endothelial cell junction and matrix adhesion proteins. Toxicology. vol 184. issue 2-3. 2003-03-18. PMID:12499124. |
western blot analysis showed thrombin stimulated catalysis of zo-1 and fak while mctp pretreatment resulted in fak fragmentation similar to previous reports for apoptosis. |
2003-03-18 |
2023-08-12 |
Not clear |
| Marco Jara, Pedro Esponda, Rosa Carballad. Abdominal temperature induces region-specific p53-independent apoptosis in the cauda epididymidis of the mouse. Biology of reproduction. vol 67. issue 4. 2003-03-11. PMID:12297535. |
the complete molecular mechanism of apoptosis in this case remains unknown, but we have used the techniques of immunocytochemistry, western blot, and reverse transcription-polymerase chain reaction to determine the role of some molecules. |
2003-03-11 |
2023-08-12 |
mouse |
| Kirstan K Meldrum, Arthur L Burnett, Xianzhong Meng, Rosalia Misseri, Matthew B K Shaw, John P Gearhart, Daniel R Meldru. Liposomal delivery of heat shock protein 72 into renal tubular cells blocks nuclear factor-kappaB activation, tumor necrosis factor-alpha production, and subsequent ischemia-induced apoptosis. Circulation research. vol 92. issue 3. 2003-03-04. PMID:12595341. |
cells were subjected to simulated ischemia 24 hours after liposomal hsp72 transfer or thermal stress, and the effect of hsp72 on nuclear factor-kappab (nf-kappab) activation (electrophoretic mobility shift assay and immunohistochemistry), ikappabalpha production (western blot), postischemic tumor necrosis factor-alpha (tnf-alpha) production (rt-pcr), and apoptosis (tunel assay) were determined. |
2003-03-04 |
2023-08-12 |
Not clear |
| K Ohnishi, I Ota, A Takahashi, K Yane, H Matsumoto, T Ohnish. Transfection of mutant p53 gene depresses X-ray- or CDDP-induced apoptosis in a human squamous cell carcinoma of the head and neck. Apoptosis : an international journal on programmed cell death. vol 7. issue 4. 2003-02-12. PMID:12101396. |
the activation of caspase-3 was estimated as an indicator of apoptosis by the detection of fragmentation of caspase-3 or poly (adp ribose) polymerase (parp) with western blot. |
2003-02-12 |
2023-08-12 |
human |
| John Gordon, Ching-Huang Wu, Mojgan Rastegar, Ahmad R Saf. Beta2-microglobulin induces caspase-dependent apoptosis in the CCRF-HSB-2 human leukemia cell line independently of the caspase-3, -8 and -9 pathways but through increased reactive oxygen species. International journal of cancer. vol 103. issue 3. 2003-01-21. PMID:12471614. |
however, z-vad-fmk treatment significantly blocked beta(2)m-induced apoptosis, while western blot analysis revealed that caspases-1, -2, -3, -6, -7, -8 and -9 are not activated during beta(2)m-induced apoptosis in these cells. |
2003-01-21 |
2023-08-12 |
human |
| Sunghoon Kim, Junghee Kang, Wanqin Hu, B Mark Evers, Dai H Chun. Geldanamycin decreases Raf-1 and Akt levels and induces apoptosis in neuroblastomas. International journal of cancer. vol 103. issue 3. 2003-01-21. PMID:12471618. |
apoptosis was assessed with dna fragmentation elisa, tunel-flow cytometric assay, western blot and caspase activities. |
2003-01-21 |
2023-08-12 |
human |
| H Ying, S Subrat. [S-phase arrest associated apoptosis leads to diversities of drug resistance and mutation rate in human breast cancer cells]. Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao. vol 30. issue 2. 2003-01-14. PMID:12212041. |
further, by means of cell growth rate test, flow cytometry, measurement of dna fragmentation and western blot, the relationship between drug resistance and mutation rate and cell cycle control and apoptosis was explored. |
2003-01-14 |
2023-08-12 |
human |
| Koichiro Yoshida, Kazuyoshi Kuwano, Naoki Hagimoto, Kentaro Watanabe, Tokuji Matsuba, Masaki Fujita, Ichiro Inoshima, Nobuyuki Har. MAP kinase activation and apoptosis in lung tissues from patients with idiopathic pulmonary fibrosis. The Journal of pathology. vol 198. issue 3. 2003-01-07. PMID:12375272. |
the expression of the active erk, jnk, and p38 mapk was examined using western blot analysis and immunohistochemistry and apoptosis was also examined by the tunel method, in lung tissues from ten patients with ipf obtained by thoracoscopic biopsy and in eight normal lung parenchyma specimens obtained by lobectomy for lung cancer. |
2003-01-07 |
2023-08-12 |
Not clear |
| Omer Kucuk, Fazlul H Sarkar, Zora Djuric, Wael Sakr, Michael N Pollak, Fred Khachik, Mousumi Banerjee, John S Bertram, David P Woo. Effects of lycopene supplementation in patients with localized prostate cancer. Experimental biology and medicine (Maywood, N.J.). vol 227. issue 10. 2002-12-19. PMID:12424329. |
biomarkers of cell proliferation and apoptosis were assessed by western blot analysis in benign and cancerous prostate tissues. |
2002-12-19 |
2023-08-12 |
human |
| Heinz Baisc. Elevated Ki-67 expression is correlated with TNFalpha- and IFNgamma-induced apoptosis in tumour cells. Cell proliferation. vol 35. issue 6. 2002-12-13. PMID:12427252. |
the ki-67 level was determined by flow cytometry and apoptosis was measured by various methods including parp degradation (western blot) in detached and floating cells. |
2002-12-13 |
2023-08-12 |
human |
| Basil F El-Rayes, Robert Grignon, Naveed Aslam, Olivia Aranha, Fazlul H Sarka. Ciprofloxacin inhibits cell growth and synergises the effect of etoposide in hormone resistant prostate cancer cells. International journal of oncology. vol 21. issue 1. 2002-12-02. PMID:12063570. |
western blot analysis of the protein extracts from these cells showed down-regulation of bcl-2, altering the ratio of bax:bcl-2 favoring apoptosis. |
2002-12-02 |
2023-08-12 |
human |
| Harold J Sheedlo, Bhooma Srinivasan, Anne Marie Brun-Zinkernagel, Criselda H Roque, Wendi Lambert, Robert J Wordinger, Rouel S Roqu. Expression of p75(NTR) in photoreceptor cells of dystrophic rat retinas. Brain research. Molecular brain research. vol 103. issue 1-2. 2002-11-06. PMID:12106693. |
in this study, the expression of p75(ntr), the low-affinity neurotrophin receptor incriminated in the apoptosis of developing neurons, was investigated at various stages of retinal degeneration in dystrophic rats using immunohistochemistry, in situ reverse transcription polymerase chain reaction (rt-pcr), western blot, and relative rt-pcr. |
2002-11-06 |
2023-08-12 |
rat |
| Joon Song, Thomas Rutherford, Frederick Naftolin, Santiago Brown, Gil Mo. Hormonal regulation of apoptosis and the Fas and Fas ligand system in human endometrial cells. Molecular human reproduction. vol 8. issue 5. 2002-10-30. PMID:11994542. |
apoptosis was determined by 3-[4,5-dimethylthiazol-2-yl]-2,5-dephenyl tetrazolium bromide (mtt) assay and propidium iodide staining, while fas and fasl expression were evaluated by western blot analysis. |
2002-10-30 |
2023-08-12 |
human |
| Hiroaki Sasaki, Shoji Fukuda, Hajime Otani, Li Zhu, Genbu Yamaura, Richard M Engelman, Dipak K Das, Nilanjana Mauli. Hypoxic preconditioning triggers myocardial angiogenesis: a novel approach to enhance contractile functional reserve in rat with myocardial infarction. Journal of molecular and cellular cardiology. vol 34. issue 3. 2002-10-21. PMID:11945025. |
western blot analysis was performed to measure vegf expression and tunel staining with endothelial cell-specific antibody, anti-vwf, was used to examine endothelial apoptosis. |
2002-10-21 |
2023-08-12 |
rat |