| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Suresh R Volate, Destiny M Davenport, Stephanie J Muga, Michael J Wargovic. Modulation of aberrant crypt foci and apoptosis by dietary herbal supplements (quercetin, curcumin, silymarin, ginseng and rutin). Carcinogenesis. vol 26. issue 8. 2005-09-20. PMID:15831530. |
western blot analysis of caspase 9, bax (proapoptotic) and bcl-2 (antiapoptotic) proteins from the colon scraping suggests that quercetin and curcumin induce apoptosis via the mitochondrial pathway. |
2005-09-20 |
2023-08-12 |
rat |
| Kazuhiro Noma, Yoshio Naomoto, Mehmet Gunduz, Junji Matsuoka, Tomoki Yamatsuji, Yasuhiro Shirakawa, Tetsuji Nobuhisa, Takaomi Okawa, Munenori Takaoka, Yasuko Tomono, Ohmori Hiroyuki, Esra Gunduz, Noriaki Tanak. Effects of imatinib vary with the types of KIT-mutation in gastrointestinal stromal tumor cell lines. Oncology reports. vol 14. issue 3. 2005-09-15. PMID:16077968. |
western blot analysis revealed that apoptosis related proteins were activated or suppressed by imatinib in both cell lines in the respective manner. |
2005-09-15 |
2023-08-12 |
Not clear |
| Hiroyuki Morimoto, Hirohiko Okamura, Kaya Yoshida, Seiichiro Kitamura, Tatsuji Hanej. Okadaic acid induces apoptosis through double-stranded RNA-dependent protein kinase/eukaryotic initiation factor-2alpha pathway in human osteoblastic MG63 cells. Journal of biochemistry. vol 136. issue 4. 2005-09-12. PMID:15625311. |
to investigate the functional relationship between phosphatases and apoptosis, we examined the phosphorylation levels of pkr and eif-2alpha by western blot analysis. |
2005-09-12 |
2023-08-12 |
human |
| Maurizio Viale, Maria A Mariggiò, Massimo Ottone, Barbara Chiavarina, Angela Vinella, Claudia Prevosto, Carlo Dell'Erba, Giovanni Petrillo, Marino Nov. Preliminary evaluation in vitro of the inhibition of cell proliferation, cytotoxicity and induction of apoptosis by 1,4-bis(1-naphthyl)-2,3-dinitro-1,3-butadiene. Investigational new drugs. vol 22. issue 4. 2005-09-07. PMID:15292706. |
the study of the induction of apoptosis was carried out by 4'-6-diamidine-2'-phenylindole (dapi) staining of segmented nuclei, western blot of p53 protein and tdt-mediated dutp-biotin nick end labeling (tunel) method, while the interaction with dna was evaluated through the analysis of interstrand cross-link (iscl) formation. |
2005-09-07 |
2023-08-12 |
human |
| Myoung-Hwa Lee, Mi-Hyeon Jang, Eun-Kyung Kim, Sang-Wan Han, Seong-Yeon Cho, Chang-Ju Ki. Nitric oxide induces apoptosis in mouse C2C12 myoblast cells. Journal of pharmacological sciences. vol 97. issue 3. 2005-08-29. PMID:15781989. |
to investigate whether nitric oxide (no) induces apoptosis in myoblast cells, the effect of the sodium nitroprusside (snp), no donor, on the apoptosis of mouse c2c12 myoblast cells was examined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay, flow cytometry, 4,6-diamidino-2-phenylindole (dapi) staining, terminal deoxynucleotidyl transferase (tdt)-mediated dutp nick end labeling (tunel) assay, dna fragmentation assay, reverse transcription-polymerase chain reaction (rt-pcr), western blot analysis, and caspase-3 enzyme assay. |
2005-08-29 |
2023-08-12 |
mouse |
| Min-Cheol Lee, Gye-Ryoung Wee, Jae-Hyoo Ki. Apoptosis of skeletal muscle on steroid-induced myopathy in rats. The Journal of nutrition. vol 135. issue 7. 2005-08-23. PMID:15987869. |
to investigate the underlying molecular changes in the apoptosis of skeletal muscle, in situ end labeling (isel), fas expression, and western blot analysis for apoptosis-related proteins in the soleus muscle of triamcinolone acetonide (ta)-induced myopathy of rats were studied. |
2005-08-23 |
2023-08-12 |
rat |
| Jun Wang, Yan-Qing Wang, Jin Yu, Xiao-Ding Cao, Gen-Cheng W. Electroacupuncture suppresses surgical trauma stress-induced lymphocyte apoptosis in rats. Neuroscience letters. vol 383. issue 1-2. 2005-08-22. PMID:15936514. |
in the present study, the effect of ea on surgical trauma stress-induced lymphocyte apoptosis was investigated by using dna gel electrophoresis, terminal deoxynucleotidyl transferase-mediated dutp nick end-labeling (tunel) assay, and western blot for fas protein expression. |
2005-08-22 |
2023-08-12 |
rat |
| Gustavo Duque, Khadija El Abdaimi, Janet E Henderson, Abderrahim Lomri, Richard Kreme. Vitamin D inhibits Fas ligand-induced apoptosis in human osteoblasts by regulating components of both the mitochondrial and Fas-related pathways. Bone. vol 35. issue 1. 2005-08-19. PMID:15207741. |
to further explore the mechanism of 1,25(oh)2d3-mediated inhibition of apoptosis, we examined the changes in activation of death domain proteins, cleavage of caspases and mitochondrial regulators of apoptosis by western blot analysis. |
2005-08-19 |
2023-08-12 |
human |
| Sebastian Stintzing, Peter Heuschmann, Letterio Barbera, Matthias Ocker, Andreas Jung, Thomas Kirchner, Daniel Neureite. Overexpression of MMP9 and tissue factor in unstable carotid plaques associated with Chlamydia pneumoniae, inflammation, and apoptosis. Annals of vascular surgery. vol 19. issue 3. 2005-08-15. PMID:15818457. |
the data on tissue remodeling were correlated with the presence of inflammatory cells (t cells, b-cells, macrophages), apoptosis, and the presence of c. pneumoniae using immunohistochemistry and western blot analyses. |
2005-08-15 |
2023-08-12 |
Not clear |
| J J Liu, R W Huang, D J Lin, J Peng, X Y Wu, Q Lin, X L Pan, Y Q Song, M H Zhang, M Hou, F Che. Expression of survivin and bax/bcl-2 in peroxisome proliferator activated receptor-gamma ligands induces apoptosis on human myeloid leukemia cells in vitro. Annals of oncology : official journal of the European Society for Medical Oncology. vol 16. issue 3. 2005-08-04. PMID:15642706. |
reverse transcription-pcr and western blot analyses demonstrated that both survivin and bcl-2 expression were downregulated markedly, while bax expression was upregulated concurrently when apoptosis occurred. |
2005-08-04 |
2023-08-12 |
human |
| Jian-Hua Zhang, Ming-Xi Wan, Bo-Rong Pan, Bing Y. Cytotoxicity of HSVtk and hrTNF-alpha fusion genes with IRES in treatment of gastric cancer. Cancer biology & therapy. vol 3. issue 11. 2005-07-21. PMID:15477756. |
the pl(tk-tnf-alpha)sn harboring hsvtk and tnf-alpha genes in sequence was constructed with a bicistronic unit including the internal ribosomal entry site, the recombinant retroviruses were transferred into sgc7901 cells by lipofectamine, and pegfp and western blot analysis were used to detect the expression of fusion genes in transfected sgc7901 cells, and then apoptosis of the transfected cells were detected by using the tdt-mediated dutp nick end labeling, flow cytometric analysis and transmission electron microscopy. |
2005-07-21 |
2023-08-12 |
mouse |
| Peng Wei, Xuan Jin, Shi-Xin Tao, Chun-Sheng Han, Yi-Xun Li. Fas, FasL, Bcl-2, and Bax in the endometrium of rhesus monkey during the menstrual cycle. Molecular reproduction and development. vol 70. issue 4. 2005-07-15. PMID:15685630. |
to study possible role and regulation of apoptosis occurred in primate endometrium, the expression of apoptosis-related molecules, fas, fasl, b cell lymphoma/leukaemia-2 (bcl-2), and bax were analyzed in relation to occurrence of apoptosis and proliferation in the cycling endometrium of the rhesus monkey using immunohistochemistry and western blot. |
2005-07-15 |
2023-08-12 |
monkey |
| Joanna Zarzyńska, Małgorzata Gajewska, Tomasz Moty. Effects of hormones and growth factors on TGF-beta1 expression in bovine mammary epithelial cells. The Journal of dairy research. vol 72. issue 1. 2005-07-06. PMID:15747730. |
rt-pcr, western blot and laser scanning cytometry (lsc) were used for analysis of tgf-beta1 transcript and protein level as well as apoptosis and cell cycle in examined mec. |
2005-07-06 |
2023-08-12 |
cattle |
| H Lee, H Park, Y J Kim, H J Kim, Y M Ahn, B Park, J H Park, B Eun Le. Expression of lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) in human preeclamptic placenta: possible implications in the process of trophoblast apoptosis. Placenta. vol 26. issue 2-3. 2005-07-05. PMID:15708124. |
in this study, we examined the expression of lox-1 in the human placentas of normal pregnancies and in preeclampsia using immunohistochemistry and western blot analysis, and proposed that lox-1 has a role in trophoblast apoptosis. |
2005-07-05 |
2023-08-12 |
human |
| Esther Llagostera, Vanessa Soto-Cerrato, Ricky Joshi, Beatriz Montaner, Pepita Gimenez-Bonafé, Ricardo Pérez-Tomá. High cytotoxic sensitivity of the human small cell lung doxorubicin-resistant carcinoma (GLC4/ADR) cell line to prodigiosin through apoptosis activation. Anti-cancer drugs. vol 16. issue 4. 2005-07-05. PMID:15746575. |
we observed through western blot that pg mediated cytochrome c release, caspase cascade activation and parp cleavage, thereby leading to apoptosis in a dose-response manner. |
2005-07-05 |
2023-08-12 |
human |
| Irina Panteleeva, Caroline Rouaux, Yves Larmet, Stéphanie Boutillier, Jean-Philippe Loeffler, Anne-Laurence Boutillie. HDAC-3 participates in the repression of e2f-dependent gene transcription in primary differentiated neurons. Annals of the New York Academy of Sciences. vol 1030. 2005-06-16. PMID:15659849. |
indeed, western blot analysis showed a time-dependent degradation of the rb/e2f binding protein hdac-3 during apoptosis, a degradation that is caspase-dependent. |
2005-06-16 |
2023-08-12 |
Not clear |
| Zhihong Hu, Mohammed M Sayee. Activation of PI3-kinase/PKB contributes to delay in neutrophil apoptosis after thermal injury. American journal of physiology. Cell physiology. vol 288. issue 5. 2005-06-09. PMID:15625305. |
expression levels of inhibitory apoptosis proteins (iaps), including cellular iap1 (ciap1), ciap2, x-linked iap (xiap), and survivin, and bcl-2 family members such as bcl-xl and bad, were determined by western blot analysis and/or rt-pcr, real-time pcr. |
2005-06-09 |
2023-08-12 |
rat |
| Y Hosaka, H Teraoka, E Yamamoto, H Ueda, K Takehan. Mechanism of cell death in inflamed superficial digital flexor tendon in the horse. Journal of comparative pathology. vol 132. issue 1. 2005-05-26. PMID:15629479. |
to detect apoptosis and to identify apoptotic cells, the samples were subjected to immunohistochemical labelling and western blot analysis. |
2005-05-26 |
2023-08-12 |
Not clear |
| Y Hosaka, H Teraoka, E Yamamoto, H Ueda, K Takehan. Mechanism of cell death in inflamed superficial digital flexor tendon in the horse. Journal of comparative pathology. vol 132. issue 1. 2005-05-26. PMID:15629479. |
excessive apoptosis was confirmed by the results of western blot analysis, which showed a significant increase in activated caspase-3 protein in the inflamed sdfts, suggesting that apoptosis occurred in the tendinocytes via a caspase-3-dependent pathway. |
2005-05-26 |
2023-08-12 |
Not clear |
| Jeong-Hyang Park, Lan Liu, In-Hee Kim, Jong-Hyun Kim, Kyung-Ran You, Dae-Ghon Ki. Identification of the genes involved in enhanced fenretinide-induced apoptosis by parthenolide in human hepatoma cells. Cancer research. vol 65. issue 7. 2005-05-26. PMID:15805281. |
the genes involved in the enhanced fenretinide-induced apoptosis by parthenolide were identified using the differential display-pcr method and subsequent northern blot or semiquantitative reverse transcriptase pcr analysis. |
2005-05-26 |
2023-08-12 |
human |