| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Balazs Hegedus, Frank W Hughes, Joel R Garbow, Scott Gianino, Debasish Banerjee, Keunyoung Kim, Mark H Ellisman, Milam A Brantley, David H Gutman. Optic nerve dysfunction in a mouse model of neurofibromatosis-1 optic glioma. Journal of neuropathology and experimental neurology. vol 68. issue 5. 2009-09-10. PMID:19525901. |
by 3 months of age, nf1+/-(gfap)cko mice exhibited pronounced optic nerve axonopathy and apoptosis of neurons in the retinal ganglion cell layer. |
2009-09-10 |
2023-08-12 |
mouse |
| Daisuke Kojima, Chun-Ho Park, Yusuke Satoh, Satoshi Inoue, Akira Noguchi, Toshifumi Oyamad. Pathology of the spinal cord of C57BL/6J mice infected with rabies virus (CVS-11 strain). The Journal of veterinary medical science. vol 71. issue 3. 2009-05-14. PMID:19346700. |
we confirmed that most of t lymphocytes and a minority of microglial cells underwent apoptosis, using a combination of tunel and immunostaining with antibodies to viral phosphoprotein, cd3, iba1 and gfap. |
2009-05-14 |
2023-08-12 |
mouse |
| Roberto G Pozner, Soledad Collado, Carolina Jaquenod de Giusti, Agustín E Ure, Marina E Biedma, Victor Romanowski, Mirta Schattner, Ricardo M Góme. Astrocyte response to Junín virus infection. Neuroscience letters. vol 445. issue 1. 2009-04-14. PMID:18771707. |
in the present work, cultured astrocytes were used to study whether jv infection could trigger inos expression and assess its eventual relationship with viral replication, glial fibrilary acidic protein (gfap) expression levels and the presence of apoptosis. |
2009-04-14 |
2023-08-12 |
Not clear |
| Qin Li, Rui Zhang, Yun-Liang Guo, Yuan-Wu Me. Effect of neuregulin on apoptosis and expressions of STAT3 and GFAP in rats following cerebral ischemic reperfusion. Journal of molecular neuroscience : MN. vol 37. issue 1. 2009-03-23. PMID:18633737. |
effect of neuregulin on apoptosis and expressions of stat3 and gfap in rats following cerebral ischemic reperfusion. |
2009-03-23 |
2023-08-12 |
rat |
| Qin Li, Rui Zhang, Yun-Liang Guo, Yuan-Wu Me. Effect of neuregulin on apoptosis and expressions of STAT3 and GFAP in rats following cerebral ischemic reperfusion. Journal of molecular neuroscience : MN. vol 37. issue 1. 2009-03-23. PMID:18633737. |
the aim is to investigate the effect of neuregulin-1beta (nrg-1beta) on the neuronal apoptosis and the expressions of signal transducer and activator of transcription (stat3) and glial fibrillary acidic protein (gfap) in rats following cerebral ischemia/reperfusion. |
2009-03-23 |
2023-08-12 |
rat |
| Mohammed Sabri, Ayako Kawashima, Jinglu Ai, R Loch Macdonal. Neuronal and astrocytic apoptosis after subarachnoid hemorrhage: a possible cause for poor prognosis. Brain research. vol 1238. 2009-02-09. PMID:18786513. |
using antibodies against neuronal marker neuronal nuclear protein (neun) and astrocyte marker glial fibrillary acidic protein (gfap) in conjunction with apoptosis marker (cleaved caspase-3), we quantified neurons and astrocytes to monitor the degree of apoptosis in both groups. |
2009-02-09 |
2023-08-12 |
dog |
| R A Barreto, C S Sousa, V D A Silva, A R Silva, E S Veloso, S D Cunha, M F D Costa, R S El-Bachá, S L Cost. Monocrotaline pyrrol is cytotoxic and alters the patterns of GFAP expression on astrocyte primary cultures. Toxicology in vitro : an international journal published in association with BIBRA. vol 22. issue 5. 2008-08-29. PMID:18474415. |
at higher concentrations (10-500 microm), astrocytes shrank their bodies and retracted their processes, presenting a more polygonal phenotype and a weaker expression on gfap labelling nuclear chromatin staining by hoechst-33258 dye, revealed condensed and fragmented chromatin in an important proportion (+/-30%) of the astrocytes exposed to 100-500 microm dhmc, suggesting signs of apoptosis. |
2008-08-29 |
2023-08-12 |
rat |
| Takayuki Tamaki, Toshihiko Matsuo, Osamu Hosoya, Kimiko M Tsutsui, Tetsuya Uchida, Kazuo Okamoto, Akihito Uji, Hiroshi Ohtsuk. Glial reaction to photoelectric dye-based retinal prostheses implanted in the subretinal space of rats. Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs. vol 11. issue 1. 2008-07-31. PMID:18414991. |
frozen sections were cut from the eyes enucleated at 1 week or 1 month and were either stained with hematoxylin and eosin, stained immunohistochemically for glial fibrillary acidic protein (gfap), or processed for in situ apoptosis detection. |
2008-07-31 |
2023-08-12 |
rat |
| Armin Alaedini, Zhaoying Xiang, Hesed Kim, Ying-Ju Sung, Norman Lato. Up-regulation of apoptosis and regeneration genes in the dorsal root ganglia during cisplatin treatment. Experimental neurology. vol 210. issue 2. 2008-06-20. PMID:18191839. |
the results indicate that cisplatin affects the expression of several genes associated with apoptosis (cdkn1a, ckap2, bid3, s100a8, s100a9), inflammation (s100a8, s100a9, cd163, mmp9), and nerve growth and regeneration (mmp9, gfap, fabp7). |
2008-06-20 |
2023-08-12 |
rat |
| Arabinda Das, Naren L Banik, Swapan K Ra. Retinoids induced astrocytic differentiation with down regulation of telomerase activity and enhanced sensitivity to taxol for apoptosis in human glioblastoma T98G and U87MG cells. Journal of neuro-oncology. vol 87. issue 1. 2008-05-21. PMID:17987264. |
treatment of cells with 1 microm all-trans retinoic acid (atra) or 1 microm 13-cis retinoic acid (13-cra) for 7 days induced astrocytic differentiation, overexpression of glial fibrillary acidic protein (gfap), and also down regulated telomerase expression and activity, thereby increased sensitivity to txl for apoptosis. |
2008-05-21 |
2023-08-12 |
human |
| M S Petrik, J M B Wilson, S C Grant, S J Blackband, R C Tabata, X Shan, C Krieger, C A Sha. Magnetic resonance microscopy and immunohistochemistry of the CNS of the mutant SOD murine model of ALS reveals widespread neural deficits. Neuromolecular medicine. vol 9. issue 3. 2007-12-27. PMID:17914180. |
increased apoptosis, gfap positive astrocytes, and/or activated microglia were observed in all those cns regions that showed volume loss except for the hippocampus. |
2007-12-27 |
2023-08-12 |
mouse |
| Xiaofan Chu, Xuejun Fu, Liangyu Zou, Chuanjie Qi, Zhuoxing Li, Yiguang Rao, Kefu M. Oncosis, the possible cell death pathway in astrocytes after focal cerebral ischemia. Brain research. vol 1149. 2007-07-16. PMID:17433269. |
scattered gfap-positive cells and ubiquitous caspase-3-positive cells were found in the core after 12 h following cerebral ischemia, and no cells positive for double-staining with tunel and gfap were found in the ischemic regions, indicating that most gfap-positive astrocytes did not die by apoptosis. |
2007-07-16 |
2023-08-12 |
rat |
| Jing Wang, Xiujie Wang, Shu Jiang, Shulan Yuan, Ping Lin, Jie Zhang, Yanrong Lu, Qi Wang, Zhujuan Xiong, Yaying Wu, Jingjing Ren, Hongliang Yan. Growth inhibition and induction of apoptosis and differentiation of tanshinone IIA in human glioma cells. Journal of neuro-oncology. vol 82. issue 1. 2007-05-17. PMID:16955220. |
its effect of apoptosis induction was detected through eb/ao staining, cell cycle analysis and the expressions of adprtl1 and cyp1a1 genes, the differentiation induction effect was investigated through morphology, mrna and protein expressions of gfap and nestin genes by rt-pcr and immunocytochemistry. |
2007-05-17 |
2023-08-12 |
human |
| Zhi-Yong Wang, Yu-Qiu Zhang, Zhi-Qi Zha. Inhibition of tetanically sciatic stimulation-induced LTP of spinal neurons and Fos expression by disrupting glutamate transporter GLT-1. Neuropharmacology. vol 51. issue 4. 2006-11-06. PMID:16815482. |
double immunofluorescence showed no fos expression in glial fibrillary acidic protein (gfap)-positive cells, and the cell dna fragment study failed to detect a significant apoptosis of spinal neurons. |
2006-11-06 |
2023-08-12 |
Not clear |
| F Behar-Cohen, D Benezra, G Soubrane, L Jonet, J C Jeann. Krypton laser photocoagulation induces retinal vascular remodeling rather than choroidal neovascularization. Experimental eye research. vol 83. issue 2. 2006-09-15. PMID:16564044. |
immunohistology using specific markers or antibodies for glial fibrillary acidic protein (gfap) (astrocytes, glia and muller's cells), von willebrand (vw) (vascular endothelial cells), tunel (cells undergoing caspase dependent apoptosis), pcna (proliferating cell nuclear antigen) p36, cd4 and f4/80 (infiltrating inflammatory and t cells), dapi (cell nuclei) and routine histology were carried out. |
2006-09-15 |
2023-08-12 |
mouse |
| David Garcia-Crespo, Ramón A Juste, Ana Hurtad. Differential gene expression in central nervous system tissues of sheep with natural scrapie. Brain research. vol 1073-1074. 2006-07-19. PMID:16458864. |
an up-regulation of genes related to glial activation (gfap) and apoptosis (casp3) was detected in obex and cerebrum, indicating a reactive glia. |
2006-07-19 |
2023-08-12 |
Not clear |
| Loïc Deleyrolle, Sophie Marchal-Victorion, Cécile Dromard, Vanessa Fritz, Monique Saunier, Jean-Charles Sabourin, Christophe Tran Van Ba, Alain Privat, Jean-Philippe Hugno. Exogenous and fibroblast growth factor 2/epidermal growth factor-regulated endogenous cytokines regulate neural precursor cell growth and differentiation. Stem cells (Dayton, Ohio). vol 24. issue 3. 2006-06-08. PMID:16166253. |
these nss have an increased growth rate associated with reduction of apoptosis and generate astrocytes with a reduced glial fibulary acidic protein (gfap) content. |
2006-06-08 |
2023-08-12 |
mouse |
| Peter E Mouser, Elizabeth Head, Kwang-Ho Ha, Troy T Roh. Caspase-mediated cleavage of glial fibrillary acidic protein within degenerating astrocytes of the Alzheimer's disease brain. The American journal of pathology. vol 168. issue 3. 2006-04-19. PMID:16507909. |
in vitro characterization of this antibody using both a cell-free system and a cell model system of apoptosis demonstrated that the antibody (termed gfap caspase-cleavage product antibody or gfap-ccp ab) immunolabeled the predicted caspase-cleavage fragment, but not full-length gfap, by western blot analysis. |
2006-04-19 |
2023-08-12 |
Not clear |
| Kathrin D Geiger, Peter Stoldt, Wolfgang Schlote, Amin Derouich. Ezrin immunoreactivity reveals specific astrocyte activation in cerebral HIV. Journal of neuropathology and experimental neurology. vol 65. issue 1. 2006-03-14. PMID:16410752. |
normal ezrin-ir, when paralleled by upregulated gfap, reflects astroglial activation not associated with neuronal apoptosis. |
2006-03-14 |
2023-08-12 |
human |
| Ravinder Pannu, Ernest Barbosa, Avtar K Singh, Inderjit Sing. Attenuation of acute inflammatory response by atorvastatin after spinal cord injury in rats. Journal of neuroscience research. vol 79. issue 3. 2005-06-10. PMID:15605375. |
in addition, neuronal apoptosis was detected 24 hr after injury followed by a profound increase in ed1-positive inflammatory infiltrates, glial fibrillary acidic protein (gfap)-positive reactive astrocytes, and oligodendrocyte apoptosis by 1 week after sci relative to control. |
2005-06-10 |
2023-08-12 |
rat |