| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pamela J Vandevord, Richard Bolander, Venkata Siva Sai Sujith Sajja, Kathryn Hay, Cynthia A Bi. Mild neurotrauma indicates a range-specific pressure response to low level shock wave exposure. Annals of biomedical engineering. vol 40. issue 1. 2012-04-24. PMID:21994066. |
histological parameters included measuring the levels of glial fibrillary acidic protein (gfap) to identify astrocyte activation, cleaved caspase-3 for early apoptosis identification and fluoro-jade b (fjb) which labels degenerating neurons within the brain tissue. |
2012-04-24 |
2023-08-12 |
rat |
| Wen Ru Yu, Michael G Fehling. Fas/FasL-mediated apoptosis and inflammation are key features of acute human spinal cord injury: implications for translational, clinical application. Acta neuropathologica. vol 122. issue 6. 2012-04-10. PMID:22038545. |
we also found significantly reduced apoptosis, expression of gfap, nf-κb, p-ikappab and iba1, increased number of cd4 positive t cells and mmp2 expression and reduced neurological dysfunction in lpr mice when compared with wt mice after sci. |
2012-04-10 |
2023-08-12 |
mouse |
| Ianors Iandiev, Mike Francke, Felix Makarov, Margrit Hollborn, Susann Uhlmann, Antje Wurm, Alexey Savvinov, Leon Kohen, Andreas Reichenbach, Peter Wiedemann, Thomas Pannicke, Andreas Bringman. Effects of intravitreal bevacizumab (Avastin) on the porcine retina. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. vol 249. issue 12. 2012-03-09. PMID:21845390. |
to evaluate the effects of intravitreal bevacizumab (avastin) on the porcine retina, with respect to structural alterations, expression of proteins involved in apoptosis (bax, caspase-3, caspase-9) and gliosis (vimentin, gfap), expression of factors which influence the development of vascular edema (vegf, pedf), and of membrane channels implicated in retinal osmohomeostasis (kir4.1, aquaporin-1, aquaporin-4). |
2012-03-09 |
2023-08-12 |
Not clear |
| Yara Maria Rauh Müller, Karoline Kobus, Janaína Chaves Schatz, Dib Ammar, Evelise Maria Nazar. Prenatal lead acetate exposure induces apoptosis and changes GFAP expression during spinal cord development. Ecotoxicology and environmental safety. vol 75. issue 1. 2012-03-06. PMID:21908043. |
prenatal lead acetate exposure induces apoptosis and changes gfap expression during spinal cord development. |
2012-03-06 |
2023-08-12 |
chicken |
| Yara Maria Rauh Müller, Karoline Kobus, Janaína Chaves Schatz, Dib Ammar, Evelise Maria Nazar. Prenatal lead acetate exposure induces apoptosis and changes GFAP expression during spinal cord development. Ecotoxicology and environmental safety. vol 75. issue 1. 2012-03-06. PMID:21908043. |
the aim of this study was to evaluate the effects of prenatal acute lead exposure on apoptosis, gfap expression, and lead deposition in the developing spinal cord. |
2012-03-06 |
2023-08-12 |
chicken |
| Yara Maria Rauh Müller, Karoline Kobus, Janaína Chaves Schatz, Dib Ammar, Evelise Maria Nazar. Prenatal lead acetate exposure induces apoptosis and changes GFAP expression during spinal cord development. Ecotoxicology and environmental safety. vol 75. issue 1. 2012-03-06. PMID:21908043. |
in ovo lead exposure induces apoptosis, and reduces gfap expression in the nervous system of the chick embryos, which may cause impairments during neuronal development and consequences in childhood and adulthood. |
2012-03-06 |
2023-08-12 |
chicken |
| Zhi-ying Hu, Jian-ying Huang, Ma-rong Fang, Jing Wang, Yan Li, Lin-zhen Wu, Ling Liu, Li Chen, Shu Ha. [Alterations of glial fibrillary acidic protein expression and neural apoptosis in brain of rat offspring born by cesarean section]. Zhonghua fu chan ke za zhi. vol 45. issue 11. 2011-11-28. PMID:21211284. |
to study changes of glial fibrillary acidic protein (gfap) expression and neural apoptosis in rat hippocampus and cortex of cesarean delivered offspring. |
2011-11-28 |
2023-08-12 |
rat |
| Bin Wang, Shi-cang Yu, Jian-yong Jiang, Gavin Wallace Porter, Lin-tao Zhao, Zhe Wang, Hong Tan, You-hong Cui, Cheng Qian, Yi-fang Ping, Xiu-wu Bia. An inhibitor of arachidonate 5-lipoxygenase, Nordy, induces differentiation and inhibits self-renewal of glioma stem-like cells. Stem cell reviews and reports. vol 7. issue 2. 2011-09-30. PMID:20809257. |
nordy appeared to exert its effect via astrocytic differentiation by up-regulation of gfap and down-regulation of stemness related genes, rather than by inducing apoptosis of gslcs. |
2011-09-30 |
2023-08-12 |
Not clear |
| Miriam Granado, Cristina García-Cáceres, María Tuda, Laura M Frago, Julie A Chowen, Jesús Argent. Insulin and growth hormone-releasing peptide-6 (GHRP-6) have differential beneficial effects on cell turnover in the pituitary, hypothalamus and cerebellum of streptozotocin (STZ)-induced diabetic rats. Molecular and cellular endocrinology. vol 337. issue 1-2. 2011-09-26. PMID:21352888. |
in the cerebellum, although insulin treatment increased gfap levels (p<0.01), only the combined treatment of insulin+ ghrp-6 decreased diabetes-induced apoptosis (p<0.05). |
2011-09-26 |
2023-08-12 |
rat |
| Yonggang Li, Pamela J Lein, Cuimei Liu, Donald A Bruun, Teclemichael Tewolde, Gregory Ford, Byron D For. Spatiotemporal pattern of neuronal injury induced by DFP in rats: a model for delayed neuronal cell death following acute OP intoxication. Toxicology and applied pharmacology. vol 253. issue 3. 2011-07-26. PMID:21513723. |
at 24h post-dfp injection, the pattern of fjb labeling corresponded to tunel staining in most brain regions, and fjb-positive cells displayed reduced neun immunoreactivity but were not immunopositive for astrocytic (gfap), oligodendroglial (o4) or macrophage/microglial (ed1) markers, demonstrating that dfp causes a region-specific delayed neuronal injury mediated in part by apoptosis. |
2011-07-26 |
2023-08-12 |
rat |
| Maria Ferletta, Demet Caglayan, Liza Mokvist, Yiwen Jiang, Marianne Kastemar, Lene Uhrbom, Bengt Westermar. Forced expression of Sox21 inhibits Sox2 and induces apoptosis in human glioma cells. International journal of cancer. vol 129. issue 1. 2011-07-04. PMID:20824710. |
reduction of sox2 expression by using sirna against sox2 or by overexpressing sox21 using a tetracycline-regulated expression system (tet-on) caused decreased gfap expression and a reduction in cell number due to induction of apoptosis. |
2011-07-04 |
2023-08-12 |
human |
| Liqun Wang, Kenneth J Colodner, Mel B Fean. Protein misfolding and oxidative stress promote glial-mediated neurodegeneration in an Alexander disease model. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 8. 2011-06-21. PMID:21414908. |
toxicity of mutant gfap to glial cells induces a non-cell-autonomous stress response and subsequent apoptosis in neurons, which is dependent on glial glutamate transport. |
2011-06-21 |
2023-08-12 |
human |
| Hai-Ping Wang, Xiao-Long Deng, Guang-Qian L. [Effects of edaravone on glial fibrillary acidic protein and interleukin-lβ expression and neuronal apoptosis in juvenile rat hippocampus after status convulsion]. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics. vol 13. issue 3. 2011-06-09. PMID:21426644. |
to study the effects of edaravone on glial fibrillary acidic protein (gfap) and interleukin-1β (il-lβ) expression and neuronal apoptosis in the juvenile rat hippocampus after status convulsion (sc). |
2011-06-09 |
2023-08-12 |
rat |
| Kosuke Saito, Noboru Fukuda, Taro Matsumoto, Yuji Iribe, Akiko Tsunemi, Tomohiko Kazama, Chikako Yoshida-Noro, Nariyuki Hayash. Moderate low temperature preserves the stemness of neural stem cells and suppresses apoptosis of the cells via activation of the cold-inducible RNA binding protein. Brain research. vol 1358. 2011-01-18. PMID:20735994. |
the meb5 mouse neural stem cell line was cultured in the presence or absence of egf, and apoptosis, mrna expression, and immunocytochemistry of the differentiation markers nestin and gfap were evaluated at 37 or 32°c. |
2011-01-18 |
2023-08-12 |
mouse |
| Kosuke Saito, Noboru Fukuda, Taro Matsumoto, Yuji Iribe, Akiko Tsunemi, Tomohiko Kazama, Chikako Yoshida-Noro, Nariyuki Hayash. Moderate low temperature preserves the stemness of neural stem cells and suppresses apoptosis of the cells via activation of the cold-inducible RNA binding protein. Brain research. vol 1358. 2011-01-18. PMID:20735994. |
the moderate low temperature prevented apoptosis and decreases in expression of gfap in meb5 by egf deprivation. |
2011-01-18 |
2023-08-12 |
mouse |
| Jin Hyoung Kim, Young Suk Yu, Kyu-Won Kim, Jeong Hun Ki. Impaired retinal vascular development in anencephalic human fetus. Histochemistry and cell biology. vol 134. issue 3. 2010-12-14. PMID:20661586. |
anencephaly (anc) and age-matched control eyes derived from each three spontaneously aborted fetus (ranging from 15 to 20 weeks gestation) were subjected to immunofluorescence staining for hif-1alpha, thy-1, glial fibrillary acidic protein (gfap) and platelet/endothelial cell adhesion molecule (pecam) and apoptosis assay. |
2010-12-14 |
2023-08-12 |
mouse |
| Dhiraj Maskey, Jonu Pradhan, Bijay Aryal, Chang-Min Lee, In-Young Choi, Ki-Sup Park, Seok Bae Kim, Hyung Gun Kim, Myeung Ju Ki. Chronic 835-MHz radiofrequency exposure to mice hippocampus alters the distribution of calbindin and GFAP immunoreactivity. Brain research. vol 1346. 2010-10-19. PMID:20546709. |
chronic rf exposure to the rat brain suggested that the decrease of cb ir accompanying apoptosis and increase of gfap ir might be morphological parameters in the hippocampus damages. |
2010-10-19 |
2023-08-12 |
mouse |
| Irene Paterniti, Emanuela Mazzon, Esposito Emanuela, Rosanna Di Paola, Maria Galuppo, Placido Bramanti, Salvatore Cuzzocre. Modulation of inflammatory response after spinal cord trauma with deferoxamine, an iron chelator. Free radical research. vol 44. issue 6. 2010-08-13. PMID:20370565. |
deferoxamine treatment 30 min before and 1 and 6 h after the sci significantly reduced: (1) gfap immunoreactivity, (2) neutrophil infiltration, (3) nf-kappab activation, (4) inos expression, (5) nitrotyrosine and mda formation, (6) dna damage (methyl green pyronin staining and par formation and (7) apoptosis (tunel staining, fasl, bax and bcl-2 expression, s-100 expression). |
2010-08-13 |
2023-08-12 |
mouse |
| Masahide Fukuda, Yoriko Nakanishi, Masanori Fuse, Norihide Yokoi, Yasuhiro Hamada, Masafumi Fukagawa, Akira Negi, Makoto Nakamur. Altered expression of aquaporins 1 and 4 coincides with neurodegenerative events in retinas of spontaneously diabetic Torii rats. Experimental eye research. vol 90. issue 1. 2010-01-15. PMID:19748503. |
this study compared temporal changes in neuroretinal apoptosis, glial fibrillary acidic protein (gfap) expression and the expression of aqps 1 and 4 between sdt rat retinas and age-matched sprague-dawley (sd) rat retinas. |
2010-01-15 |
2023-08-12 |
rat |
| Masahide Fukuda, Yoriko Nakanishi, Masanori Fuse, Norihide Yokoi, Yasuhiro Hamada, Masafumi Fukagawa, Akira Negi, Makoto Nakamur. Altered expression of aquaporins 1 and 4 coincides with neurodegenerative events in retinas of spontaneously diabetic Torii rats. Experimental eye research. vol 90. issue 1. 2010-01-15. PMID:19748503. |
thus, the development of diabetes increases neuroretinal apoptosis, and this coincides with an altered expression pattern of gfap and water-selective channels aqps 1 and 4 in sdt rats. |
2010-01-15 |
2023-08-12 |
rat |