| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zifeng Zhang, Zheng Huang, Hao Dai, Licheng Wei, Songtao Sun, Feng Ga. Therapeutic Efficacy of E-64-d, a Selective Calpain Inhibitor, in Experimental Acute Spinal Cord Injury. BioMed research international. vol 2015. 2016-04-13. PMID:26240815. |
treatment with e-64-d decreased expressions of calpain 1 and gfap, alleviated neuronal apoptosis, inhibited cyclooxygenase-2 activity, and resulted in the promoted locomotor function. |
2016-04-13 |
2023-08-13 |
rat |
| Nagehan Can, Onur Catak, Burak Turgut, Tamer Demir, Nevin Ilhan, Tuncay Kuloglu, Ibrahim Hanifi Ozerca. Neuroprotective and antioxidant effects of ghrelin in an experimental glaucoma model. Drug design, development and therapy. vol 9. 2016-02-15. PMID:26082612. |
retinal tunel and immunohistochemistry staining in the vehicle control group showed an increase in apoptosis and expression of gfap, s-100, and vimentin compared with the control group (p<0.05). |
2016-02-15 |
2023-08-13 |
rat |
| Nagehan Can, Onur Catak, Burak Turgut, Tamer Demir, Nevin Ilhan, Tuncay Kuloglu, Ibrahim Hanifi Ozerca. Neuroprotective and antioxidant effects of ghrelin in an experimental glaucoma model. Drug design, development and therapy. vol 9. 2016-02-15. PMID:26082612. |
in the ghrelin group, apoptosis and expression of gfap, s-100, and vimentin was significantly lower than in the vehicle control group (p<0.05). |
2016-02-15 |
2023-08-13 |
rat |
| B C Pereira, G Lucas, A L da Rocha, J R Pauli, E R Ropelle, D Cintra, C T de Souza, C R Bueno, A S da Silv. Eccentric Exercise Leads to Glial Activation but not Apoptosis in Mice Spinal Cords. International journal of sports medicine. vol 36. issue 5. 2016-01-19. PMID:25665003. |
gfap and iba-1) neurons without leading to apoptosis. |
2016-01-19 |
2023-08-13 |
mouse |
| Sang In Park, Sang Kyu Park, Kyoung Sool Jang, Yong Min Han, Choong Hyeon Kim, Seok Jeon O. Preischemic neuroprotective effect of minocycline and sodium ozagrel on transient cerebral ischemic rat model. Brain research. vol 1599. 2015-12-01. PMID:25555371. |
immunohistofluorescence staining showed a higher number of neun positive cells, lower activated astrocytes in gfap and a lower apoptosis in tunel staining. |
2015-12-01 |
2023-08-13 |
rat |
| Liuqi Yang, Huijie Guo, Lihua Dong, Li Wang, Chunlan Liu, Xiujie Wan. Tanshinone IIA inhibits the growth, attenuates the stemness and induces the apoptosis of human glioma stem cells. Oncology reports. vol 32. issue 3. 2015-11-03. PMID:24970314. |
furthermore, tanshinone iia increased the expression of differentiation and neural lineage markers including gfap and β-tubulin, decreased expression of gsc markers including cd133 and nestin, and induced gsc apoptosis in vitro and in vivo in a dose‑dependent manner. |
2015-11-03 |
2023-08-13 |
human |
| Hong Xu, Thomas W Rösler, Thomas Carlsson, Anderson de Andrade, Ondrej Fiala, Matthias Hollerhage, Wolfgang H Oertel, Michel Goedert, Achim Aigner, Gunter U Höglinge. Tau silencing by siRNA in the P301S mouse model of tauopathy. Current gene therapy. vol 14. issue 5. 2015-10-13. PMID:25687501. |
neun, gfap, iba-1, mhc ii immunoreactivities and the terminal deoxynucleotidyl transferase dutp nick end labeling (tunel) assay showed neither signs of neurotoxicity or neuroinflammation nor apoptosis when mapt sirna is present in the hippocampus. |
2015-10-13 |
2023-08-13 |
mouse |
| Tian-Zun Li, Yi Yan, Qiang Liu, Yong-Zhi Xi. [Effect of suppressing apoptosis signal regulating kinase 1 on GFAP and vimentin expression and hindlimb mobility in rats after spinal cord injury]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 35. issue 6. 2015-09-25. PMID:26111673. |
[effect of suppressing apoptosis signal regulating kinase 1 on gfap and vimentin expression and hindlimb mobility in rats after spinal cord injury]. |
2015-09-25 |
2023-08-13 |
rat |
| Tian-Zun Li, Yi Yan, Qiang Liu, Yong-Zhi Xi. [Effect of suppressing apoptosis signal regulating kinase 1 on GFAP and vimentin expression and hindlimb mobility in rats after spinal cord injury]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 35. issue 6. 2015-09-25. PMID:26111673. |
to investigate the effect of suppressing apoptosis signal regulating kinase 1 (ask1) on glial fibrillary acidic protein (gfap) and vimentin expressions at the injury site and on hindlimb mobility in rats after spinal cord injury (sci). |
2015-09-25 |
2023-08-13 |
rat |
| Weiyi Huang, Bingke Lv, Huijun Zeng, Dandan Shi, Yi Liu, Fanfan Chen, Feng Li, Xinghui Liu, Rong Zhu, Lei Yu, Xiaodan Jian. Paracrine Factors Secreted by MSCs Promote Astrocyte Survival Associated With GFAP Downregulation After Ischemic Stroke via p38 MAPK and JNK. Journal of cellular physiology. vol 230. issue 10. 2015-09-21. PMID:25752945. |
the results indicated that both situations could protect astrocytes from apoptosis, increase cell metabolic activity, and reduce glial fibrillary acidic protein (gfap) overexpression; however, the effects of co-culturing with mscs were more positive. |
2015-09-21 |
2023-08-13 |
Not clear |
| Anusha Hemamali Tennakoon, Takeshi Izawa, Kavindra Kumara Wijesundera, Hiroshi Murakami, Chisa Katou-Ichikawa, Miyuu Tanaka, Hossain M Golbar, Mitsuru Kuwamura, Jyoji Yamat. Immunohistochemical characterization of glial fibrillary acidic protein (GFAP)-expressing cells in a rat liver cirrhosis model induced by repeated injections of thioacetamide (TAA). Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. vol 67. issue 1. 2015-08-05. PMID:25446803. |
a few gfap expressing cells underwent both mitosis and apoptosis. |
2015-08-05 |
2023-08-13 |
rat |
| Li Ding, Xiang Gao, Shenghui Yu, Jianping Yan. Effects of mild and moderate hypothemia therapy on expression of cerebral neuron apoptosis related proteins and glial fiber acidic protein after rat cardio-pulmonary resuscitation. Cell biochemistry and biophysics. vol 70. issue 3. 2015-07-07. PMID:25108738. |
hypothermia-regulated gfap expression by decreasing caspase-3 expression and increasing bcl-2 expression to promote brain cell signaling transduction, and further inhibited cell apoptosis and reduced brain injury. |
2015-07-07 |
2023-08-13 |
rat |
| S Arici, S Karaman, S Dogru, S Cayli, A Arici, M Suren, T Karaman, Z Kay. Central nervous system toxicity after acute oral formaldehyde exposure in rabbits: An experimental study. Human & experimental toxicology. vol 33. issue 11. 2015-06-23. PMID:24501105. |
the gfap level was found to be significantly higher in group f. in conclusion, acute oral exposure to fa caused dna damage, apoptosis, and neuronal injury in the rabbit brains. |
2015-06-23 |
2023-08-12 |
rabbit |
| Vijayan Ranju, Sekar Sathiya, Periyathambi Kalaivani, Raju Jyothi Priya, Chidambaram Saravana Bab. Memantine exerts functional recovery by improving BDNF and GDNF expression in 3-nitropropionic acid intoxicated mice. Neuroscience letters. vol 586. 2015-05-14. PMID:25475686. |
mn ameliorated striatal neuronal loss, reduced gfap immunoreactivity, and exhibited protective effect against neuronal apoptosis. |
2015-05-14 |
2023-08-13 |
mouse |
| Patricia Rivera, Laura Bindila, Antoni Pastor, Margarita Pérez-Martín, Francisco J Pavón, Antonia Serrano, Rafael de la Torre, Beat Lutz, Fernando Rodríguez de Fonseca, Juan Suáre. Pharmacological blockade of the fatty acid amide hydrolase (FAAH) alters neural proliferation, apoptosis and gliosis in the rat hippocampus, hypothalamus and striatum in a negative energy context. Frontiers in cellular neuroscience. vol 9. 2015-04-14. PMID:25870539. |
cell proliferation (phospho-h3(+) or brdu(+) cells) of the main adult neurogenic zones as well as apoptosis (cleaved caspase-3(+)), astroglia (gfap(+)), and microglia (iba1(+) cells) were analyzed in the hippocampus, hypothalamus and striatum of rats intraperitoneally treated with urb597 (0.3 mg/kg/day) at one dose/4-days resting or 5 doses (1 dose/day). |
2015-04-14 |
2023-08-13 |
rat |
| Qiaoyu Sun, Ya Ou, Shujuan Wang, Xiaodong Yuan, Wenjiang Zhang, Hongliang Deng, Lili Zhan. The effect of autophagy in the process of adipose-derived stromal cells differentiation into astrocytes. Journal of molecular neuroscience : MN. vol 53. issue 4. 2015-04-06. PMID:24420732. |
we observed that the differentiation ratio, the number of living cells, and the positive expression rates of gfap in the rapamycin group were higher than those in the control group when adscs were induced for 48 h and 7 days (p < 0.01); however, the rates of early apoptosis were lower than those in the control group. |
2015-04-06 |
2023-08-12 |
Not clear |
| Wei Jiang, Guobiao Liang, Xiaoming Li, Zhiqing Li, Xu Gao, Sizhe Feng, Xiaogang Wang, Minpei Liu, Yang Li. Intracarotid transplantation of autologous adipose-derived mesenchymal stem cells significantly improves neurological deficits in rats after MCAo. Journal of materials science. Materials in medicine. vol 25. issue 5. 2014-11-28. PMID:24469290. |
the apoptosis and astroglial reactivity were determined by tunel and glial fibrillary acidic protein (gfap) staining, respectively. |
2014-11-28 |
2023-08-12 |
rat |
| Jian-Gang Wang, Stephen C Bondy, Li Zhou, Feng-Zhen Yang, Zhi-Gang Ding, Yu Hu, Yun Tian, Pu-Yuan Wen, Hao Luo, Fang Wang, Wen-Wen Li, Jun Zho. Protective effect of Tanshinone IIA against infarct size and increased HMGB1, NFκB, GFAP and apoptosis consequent to transient middle cerebral artery occlusion. Neurochemical research. vol 39. issue 2. 2014-10-07. PMID:24362639. |
protective effect of tanshinone iia against infarct size and increased hmgb1, nfκb, gfap and apoptosis consequent to transient middle cerebral artery occlusion. |
2014-10-07 |
2023-08-12 |
rat |
| Stephanie C Joachim, Christine Mondon, Oliver W Gramlich, Franz H Grus, H Burkhard Dic. Apoptotic retinal ganglion cell death in an autoimmune glaucoma model is accompanied by antibody depositions. Journal of molecular neuroscience : MN. vol 52. issue 2. 2014-10-06. PMID:24091788. |
at 8 days no significant apoptosis or difference in rgcs was noted, but ona retinas had a significantly higher gfap(+) area (p = 0.02). |
2014-10-06 |
2023-08-12 |
rat |
| A Rai, S Tripathi, R Kushwaha, P Singh, P Srivastava, S Sanyal, S Bandyopadhya. CDK5-induced p-PPARγ(Ser 112) downregulates GFAP via PPREs in developing rat brain: effect of metal mixture and troglitazone in astrocytes. Cell death & disease. vol 5. 2014-09-02. PMID:24481447. |
here, we investigated the role of pparγ in regulating gfap using a mixture of as, cd and pb (metal mixture, mm) that induces apoptosis and aberrant morphology in rat brain astrocytes. |
2014-09-02 |
2023-08-12 |
rat |