| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jiayu Diao, Jin Wei, Rui Yan, Xin Liu, Qing Li, Lin Lin, Yanhe Zhu, Hong L. Rosmarinic Acid suppressed high glucose-induced apoptosis in H9c2 cells by ameliorating the mitochondrial function and activating STAT3. Biochemical and biophysical research communications. vol 477. issue 4. 2017-05-15. PMID:27402269. |
rosmarinic acid suppressed high glucose-induced apoptosis in h9c2 cells by ameliorating the mitochondrial function and activating stat3. |
2017-05-15 |
2023-08-13 |
Not clear |
| Jiayu Diao, Jin Wei, Rui Yan, Xin Liu, Qing Li, Lin Lin, Yanhe Zhu, Hong L. Rosmarinic Acid suppressed high glucose-induced apoptosis in H9c2 cells by ameliorating the mitochondrial function and activating STAT3. Biochemical and biophysical research communications. vol 477. issue 4. 2017-05-15. PMID:27402269. |
the present study was undertaken to determine the relationship between ra and stat3 activation, as well as their effects on high glucose-induced mitochondrial injury and apoptosis in h9c2 cardiomyocyte. |
2017-05-15 |
2023-08-13 |
Not clear |
| Jiayu Diao, Jin Wei, Rui Yan, Xin Liu, Qing Li, Lin Lin, Yanhe Zhu, Hong L. Rosmarinic Acid suppressed high glucose-induced apoptosis in H9c2 cells by ameliorating the mitochondrial function and activating STAT3. Biochemical and biophysical research communications. vol 477. issue 4. 2017-05-15. PMID:27402269. |
importantly, inhibition of stat3 expression by using stat3-sirna partly suppressed the effect of ra on high glucose-induced apoptosis. |
2017-05-15 |
2023-08-13 |
Not clear |
| Jiayu Diao, Jin Wei, Rui Yan, Xin Liu, Qing Li, Lin Lin, Yanhe Zhu, Hong L. Rosmarinic Acid suppressed high glucose-induced apoptosis in H9c2 cells by ameliorating the mitochondrial function and activating STAT3. Biochemical and biophysical research communications. vol 477. issue 4. 2017-05-15. PMID:27402269. |
taken together, pretreatment with ra suppressed high glucose-induced apoptosis in cardiomyocyte by ameliorating mitochondrial function and activating stat3. |
2017-05-15 |
2023-08-13 |
Not clear |
| Sanya-Eduarda Kuzet, Cedric Gaggiol. Fibroblast activation in cancer: when seed fertilizes soil. Cell and tissue research. vol 365. issue 3. 2017-05-15. PMID:27474009. |
upon lif stimulation, jak is phosphorylated and further activates stat3, a transcriptional factor that is then translocated into the nucleus where it promotes the transcription of genes responsible for cell growth, differentiation, proliferation and apoptosis. |
2017-05-15 |
2023-08-13 |
Not clear |
| M A Crookenden, A Heiser, A Murray, V S R Dukkipati, J K Kay, J J Loor, S Meier, M D Mitchell, K M Moyes, C G Walker, J R Roch. Parturition in dairy cows temporarily alters the expression of genes in circulating neutrophils. Journal of dairy science. vol 99. issue 8. 2017-05-12. PMID:27179873. |
genes that were differentially expressed over the transition period included those involved in neutrophil adhesion (sell, itgb2, and itgbx), mediation of the immune response (tlr4, hla-dra, and cxcr2), maturation, cell cycle progression, apoptosis (mcl1, bcl2, faslg, and ripk1), and control of gene expression (pparg, ppard, and stat3). |
2017-05-12 |
2023-08-13 |
Not clear |
| Xing Bao, Tingting Ren, Yi Huang, Chongmin Ren, Kang Yang, Hongliang Zhang, Wei Gu. Bortezomib induces apoptosis and suppresses cell growth and metastasis by inactivation of Stat3 signaling in chondrosarcoma. International journal of oncology. vol 50. issue 2. 2017-04-27. PMID:28000897. |
bortezomib induces apoptosis and suppresses cell growth and metastasis by inactivation of stat3 signaling in chondrosarcoma. |
2017-04-27 |
2023-08-13 |
Not clear |
| Xing Bao, Tingting Ren, Yi Huang, Chongmin Ren, Kang Yang, Hongliang Zhang, Wei Gu. Bortezomib induces apoptosis and suppresses cell growth and metastasis by inactivation of Stat3 signaling in chondrosarcoma. International journal of oncology. vol 50. issue 2. 2017-04-27. PMID:28000897. |
accordingly, small interfering rna (sirna)-mediated stat3 knockdown enhanced bortezomib-induced apoptosis, and concomitantly enhanced the inhibitory effect of bortezomib on cell viability, migration and invasion. |
2017-04-27 |
2023-08-13 |
Not clear |
| Xing Bao, Tingting Ren, Yi Huang, Chongmin Ren, Kang Yang, Hongliang Zhang, Wei Gu. Bortezomib induces apoptosis and suppresses cell growth and metastasis by inactivation of Stat3 signaling in chondrosarcoma. International journal of oncology. vol 50. issue 2. 2017-04-27. PMID:28000897. |
in vivo, bortezomib downregulated stat3 activity and mesenchymal cell marker expression, induced apoptosis and inhibition of metastasis and tumor growth. |
2017-04-27 |
2023-08-13 |
Not clear |
| Jian-Guang Yang, Rui Lu, Xiao-Jing Ye, Jing Zhang, Ya-Qin Tan, Gang Zho. Icaritin Reduces Oral Squamous Cell Carcinoma Progression via the Inhibition of STAT3 Signaling. International journal of molecular sciences. vol 18. issue 1. 2017-04-24. PMID:28085115. |
the expressions of proteins related to proliferation, apoptosis, and autophagy, as well as signal transducer and activator of transcription 3 (stat3) signal network, were also evaluated by western blot. |
2017-04-24 |
2023-08-13 |
mouse |
| Jian-Guang Yang, Rui Lu, Xiao-Jing Ye, Jing Zhang, Ya-Qin Tan, Gang Zho. Icaritin Reduces Oral Squamous Cell Carcinoma Progression via the Inhibition of STAT3 Signaling. International journal of molecular sciences. vol 18. issue 1. 2017-04-24. PMID:28085115. |
furthermore, stat3 was knocked down by sirna transfection to determine stat3 role in oscc cell proliferation and apoptosis. |
2017-04-24 |
2023-08-13 |
mouse |
| Jian-Guang Yang, Rui Lu, Xiao-Jing Ye, Jing Zhang, Ya-Qin Tan, Gang Zho. Icaritin Reduces Oral Squamous Cell Carcinoma Progression via the Inhibition of STAT3 Signaling. International journal of molecular sciences. vol 18. issue 1. 2017-04-24. PMID:28085115. |
overall, icaritin suppressed proliferation, promoted apoptosis and autophagy, and inhibited stat3 signaling in oscc in vitro and in vivo. |
2017-04-24 |
2023-08-13 |
mouse |
| Xia Bai, Junpeng Luo, Xiaofeng Zhang, Jingjing Han, Zhaoyue Wang, Jingcheng Miao, Yanyan Ba. MicroRNA-126 Reduces Blood-Retina Barrier Breakdown via the Regulation of VCAM-1 and BCL2L11 in Ischemic Retinopathy. Ophthalmic research. vol 57. issue 3. 2017-04-20. PMID:28076855. |
our results suggested that mir-126 may not only regulate the overexpression of vcam-1 or bcl2l11 and lead to the reduction of retinal endothelial cell apoptosis, retinal vascular leakage, or retinal permeability in the oir mouse model, but may also protect hypoxic retinal müller cells via the stat3 signaling pathway. |
2017-04-20 |
2023-08-13 |
mouse |
| Jianheng Wu, Linfan Li, Guangyuan Jiang, Hui Zhan, Nannan Wan. B-cell CLL/lymphoma 3 promotes glioma cell proliferation and inhibits apoptosis through the oncogenic STAT3 pathway. International journal of oncology. vol 49. issue 6. 2017-04-17. PMID:27748795. |
b-cell cll/lymphoma 3 promotes glioma cell proliferation and inhibits apoptosis through the oncogenic stat3 pathway. |
2017-04-17 |
2023-08-13 |
mouse |
| Jianheng Wu, Linfan Li, Guangyuan Jiang, Hui Zhan, Nannan Wan. B-cell CLL/lymphoma 3 promotes glioma cell proliferation and inhibits apoptosis through the oncogenic STAT3 pathway. International journal of oncology. vol 49. issue 6. 2017-04-17. PMID:27748795. |
in conclusion, we suggest that bcl3 serves as an oncogene in glioma by modulating proliferation, cell cycle progression and apoptosis, and its oncogenic effects are mediated by the stat3 signaling pathway. |
2017-04-17 |
2023-08-13 |
mouse |
| Ziwei Miao, Fei Yu, Yahao Ren, Jun Yan. d,l-Sulforaphane Induces ROS-Dependent Apoptosis in Human Gliomablastoma Cells by Inactivating STAT3 Signaling Pathway. International journal of molecular sciences. vol 18. issue 1. 2017-04-13. PMID:28054986. |
d,l-sulforaphane induces ros-dependent apoptosis in human gliomablastoma cells by inactivating stat3 signaling pathway. |
2017-04-13 |
2023-08-13 |
human |
| Toru Oi, Kunihiro Asanuma, Akihiko Matsumine, Takao Matsubara, Tomoki Nakamura, Takahiro Iino, Yumiko Asanuma, Mikinobu Goto, Kazuma Okuno, Takuya Kakimoto, Yuki Yada, Akihiro Sud. STAT3 inhibitor, cucurbitacin I, is a novel therapeutic agent for osteosarcoma. International journal of oncology. vol 49. issue 6. 2017-04-07. PMID:27840900. |
following cucurbitacin i treatment, stat3 was inactivated and analysis of mcl-1, cleaved parp and caspase-3 indicated apoptosis induction. |
2017-04-07 |
2023-08-13 |
mouse |
| Yanli Gu, Jing Wang, Lixin Pen. (-)-Oleocanthal exerts anti-melanoma activities and inhibits STAT3 signaling pathway. Oncology reports. vol 37. issue 1. 2017-04-07. PMID:27878290. |
oc also downregulated stat3 target genes, including mcl-1, bcl-xl, mmp-2, mmp-9, vegf, which are involved in apoptosis, invasion and angiogenesis of melanoma. |
2017-04-07 |
2023-08-13 |
human |
| Xuerong Zhao, Jianping Wang, Lijun Xiao, Qian Xu, Enhong Zhao, Xin Zheng, Huachuan Zheng, Shuang Zhao, Shi Din. Effects of 17-AAG on the cell cycle and apoptosis of H446 cells and the associated mechanisms. Molecular medicine reports. vol 14. issue 2. 2017-04-06. PMID:27279418. |
the results indicated that 17‑aag is able to inhibit the cell proliferation, induce apoptosis and g2/m arrest and downregulate the gene and protein expression levels of stat3, survivin and cyclin d1, and upregulate gene and protein expression of cyt‑c, caspase 9, caspase 3. |
2017-04-06 |
2023-08-13 |
Not clear |
| Jeong-Hyeon Ko, Seung Ho Baek, Dongwoo Nam, Won-Seok Chung, Seok-Geun Lee, Junhee Lee, Woong Mo Yang, Jae-Young Um, Kwang Seok Ah. 3-Formylchromone inhibits proliferation and induces apoptosis of multiple myeloma cells by abrogating STAT3 signaling through the induction of PIAS3. Immunopharmacology and immunotoxicology. vol 38. issue 5. 2017-03-21. PMID:27324722. |
3-formylchromone inhibits proliferation and induces apoptosis of multiple myeloma cells by abrogating stat3 signaling through the induction of pias3. |
2017-03-21 |
2023-08-13 |
Not clear |