| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yuqing Ge, Bo Yang, Zhe Chen, Rubin Chen. Cryptotanshinone suppresses the proliferation and induces the apoptosis of pancreatic cancer cells via the STAT3 signaling pathway. Molecular medicine reports. vol 12. issue 5. 2016-08-15. PMID:26459366. |
cryptotanshinone suppresses the proliferation and induces the apoptosis of pancreatic cancer cells via the stat3 signaling pathway. |
2016-08-15 |
2023-08-13 |
human |
| Yuqing Ge, Bo Yang, Zhe Chen, Rubin Chen. Cryptotanshinone suppresses the proliferation and induces the apoptosis of pancreatic cancer cells via the STAT3 signaling pathway. Molecular medicine reports. vol 12. issue 5. 2016-08-15. PMID:26459366. |
the present study demonstrated that cpt exerts anticancer effects by inducing apoptosis and cell cycle arrest via inhibition of the stat3 signaling pathway in human bxpc-3 cells. |
2016-08-15 |
2023-08-13 |
human |
| B Zhao, A-S Don. MiR-874 inhibits cell growth and induces apoptosis by targeting STAT3 in human colorectal cancer cells. European review for medical and pharmacological sciences. vol 20. issue 2. 2016-08-11. PMID:26875895. |
mir-874 inhibits cell growth and induces apoptosis by targeting stat3 in human colorectal cancer cells. |
2016-08-11 |
2023-08-13 |
human |
| Xuenong Zhang, Yanyan Wang, Shishi Han, Huiyao Xiang, Yan Peng, Yinghua Wu, Songwei Pan, Ye Zhang, Jinlan Rua. RY10-4 Inhibits the Proliferation of Human Hepatocellular Cancer HepG2 Cells by Inducing Apoptosis In Vitro and In Vivo. PloS one. vol 11. issue 3. 2016-08-08. PMID:26974964. |
moreover, ry10-4 caused the suppression of stat3 activation, which may be involved the apoptosis induction. |
2016-08-08 |
2023-08-13 |
human |
| Wei Cao, Ying Liu, Ran Zhang, Bo Zhang, Teng Wang, Xianbing Zhu, Lin Mei, Hongbo Chen, Hongling Zhang, Pinghong Ming, Laiqiang Huan. Homoharringtonine induces apoptosis and inhibits STAT3 via IL-6/JAK1/STAT3 signal pathway in Gefitinib-resistant lung cancer cells. Scientific reports. vol 5. 2016-08-05. PMID:26166037. |
homoharringtonine induces apoptosis and inhibits stat3 via il-6/jak1/stat3 signal pathway in gefitinib-resistant lung cancer cells. |
2016-08-05 |
2023-08-13 |
Not clear |
| Migyeong Jeong, Jong-Min Park, Young-Min Han, Kun Young Park, Don Haeng Lee, Joon-Hwan Yoo, Joo Young Cho, Ki-Baik Hah. Dietary prevention of Helicobacter pylori-associated gastric cancer with kimchi. Oncotarget. vol 6. issue 30. 2016-08-02. PMID:26317548. |
on molecular analysis, significant expressions of cox-2 and il-6, activated nf-κb and stat3, increased apoptosis, and marked oxidative stresses were noted in h. pylori-infected group relevant to tumorigenesis, but these were all significantly attenuated in cpkimchi group. |
2016-08-02 |
2023-08-13 |
mouse |
| Li-Ching Fan, Hao-Wei Teng, Chung-Wai Shiau, Wei-Tien Tai, Man-Hsin Hung, Shung-Haur Yang, Jeng-Kai Jiang, Kuen-Feng Che. Pharmacological Targeting SHP-1-STAT3 Signaling Is a Promising Therapeutic Approach for the Treatment of Colorectal Cancer. Neoplasia (New York, N.Y.). vol 17. issue 9. 2016-08-01. PMID:26476076. |
our previous data demonstrated that regorafenib (stivarga) is a pharmacological agonist of sh2 domain-containing phosphatase 1 (shp-1) that enhances shp-1 activity and induces apoptosis by targeting stat3 signals in crc. |
2016-08-01 |
2023-08-13 |
human |
| Ji-Wei Ma, Yong Zhang, Ru Li, Jie-Cheng Ye, Hai-Ying Li, Yi-Kai Zhang, Zheng-Lai Ma, Jin-Ying Li, Xue-Yun Zhong, Xuesong Yan. Tetrandrine suppresses human glioma growth by inhibiting cell survival, proliferation and tumour angiogenesis through attenuating STAT3 phosphorylation. European journal of pharmacology. vol 764. 2016-07-28. PMID:26086859. |
in sum, our data indicate that stat3 is involved in tet-induced the regression of glioma growth by activating tumour cell apoptosis, inhibiting glioma cell proliferation and inhibiting angiogenesis. |
2016-07-28 |
2023-08-13 |
human |
| Sadeesh Em, Fozia Shah, Meena Kataria, P S Yada. A comparative study on expression profile of developmentally important genes during pre-implantation stages in buffalo hand-made cloned embryos derived from adult fibroblasts and amniotic fluid derived stem cells. Cytotechnology. vol 68. issue 4. 2016-07-26. PMID:26224482. |
alterations in the expression pattern of genes implicated in transcription and pluripotency (oct4, stat3, nanog), dna methylation (dnmt1, dnmt3a), histone deacetylation (hdac2), growth factor signaling, and imprinting (igf2, igf2r), apoptosis (bax, bcl2), oxidative stress (mnsod), metabolism (glut1) regulation were observed in cloned embryos. |
2016-07-26 |
2023-08-13 |
Not clear |
| Yanmin Zhang, Zhaoxiao Du, Zirong Zhuang, Yanjun Wang, Fen Wang, Shuai Liu, Han Wang, Hairong Feng, Haoyuan Li, Liyan Wang, Xianghong Zhang, Aijun Ha. E804 induces growth arrest, differentiation and apoptosis of glioblastoma cells by blocking Stat3 signaling. Journal of neuro-oncology. vol 125. issue 2. 2016-07-25. PMID:26386687. |
e804 induces growth arrest, differentiation and apoptosis of glioblastoma cells by blocking stat3 signaling. |
2016-07-25 |
2023-08-13 |
human |
| Yanmin Zhang, Zhaoxiao Du, Zirong Zhuang, Yanjun Wang, Fen Wang, Shuai Liu, Han Wang, Hairong Feng, Haoyuan Li, Liyan Wang, Xianghong Zhang, Aijun Ha. E804 induces growth arrest, differentiation and apoptosis of glioblastoma cells by blocking Stat3 signaling. Journal of neuro-oncology. vol 125. issue 2. 2016-07-25. PMID:26386687. |
consistently, reduction of stat3 activity promotes e804-mediated anti-tumor effects, whereas overexpression of stat3c mutant recues cell apoptosis induced by e804. |
2016-07-25 |
2023-08-13 |
human |
| Yanmin Zhang, Zhaoxiao Du, Zirong Zhuang, Yanjun Wang, Fen Wang, Shuai Liu, Han Wang, Hairong Feng, Haoyuan Li, Liyan Wang, Xianghong Zhang, Aijun Ha. E804 induces growth arrest, differentiation and apoptosis of glioblastoma cells by blocking Stat3 signaling. Journal of neuro-oncology. vol 125. issue 2. 2016-07-25. PMID:26386687. |
taken together, our results indicate that e804 can effectively suppress tumor cell growth, induce tumor cell differentiation and apoptosis mediated partially by stat3 signaling pathway, suggesting that e804 could be useful for a potential anti-glioblastoma therapeutic approach. |
2016-07-25 |
2023-08-13 |
human |
| Jin Mo Ku, Soon Re Kim, Se Hyang Hong, Han-Seok Choi, Hye Sook Seo, Yong Cheol Shin, Seong-Gyu K. Cucurbitacin D induces cell cycle arrest and apoptosis by inhibiting STAT3 and NF-κB signaling in doxorubicin-resistant human breast carcinoma (MCF7/ADR) cells. Molecular and cellular biochemistry. vol 409. issue 1-2. 2016-07-22. PMID:26169986. |
cucurbitacin d induces cell cycle arrest and apoptosis by inhibiting stat3 and nf-κb signaling in doxorubicin-resistant human breast carcinoma (mcf7/adr) cells. |
2016-07-22 |
2023-08-13 |
human |
| Jin Mo Ku, Soon Re Kim, Se Hyang Hong, Han-Seok Choi, Hye Sook Seo, Yong Cheol Shin, Seong-Gyu K. Cucurbitacin D induces cell cycle arrest and apoptosis by inhibiting STAT3 and NF-κB signaling in doxorubicin-resistant human breast carcinoma (MCF7/ADR) cells. Molecular and cellular biochemistry. vol 409. issue 1-2. 2016-07-22. PMID:26169986. |
co-administration of cucurbitacin d and doxorubicin induced apoptosis, and g2/m cell cycle arrest, and inhibited upregulated stat3 by doxorubicin on mcf7/adr cells. |
2016-07-22 |
2023-08-13 |
human |
| Jin Mo Ku, Soon Re Kim, Se Hyang Hong, Han-Seok Choi, Hye Sook Seo, Yong Cheol Shin, Seong-Gyu K. Cucurbitacin D induces cell cycle arrest and apoptosis by inhibiting STAT3 and NF-κB signaling in doxorubicin-resistant human breast carcinoma (MCF7/ADR) cells. Molecular and cellular biochemistry. vol 409. issue 1-2. 2016-07-22. PMID:26169986. |
cucurbitacin d decreases cell proliferation and induces apoptosis by inhibiting stat3 and nf-κb signaling in doxorubicin-resistant breast cancer cells. |
2016-07-22 |
2023-08-13 |
human |
| Andrea M Griesinger, Rebecca J Josephson, Andrew M Donson, Jean M Mulcahy Levy, Vladimir Amani, Diane K Birks, Lindsey M Hoffman, Steffanie L Furtek, Phillip Reigan, Michael H Handler, Rajeev Vibhakar, Nicholas K Forema. Interleukin-6/STAT3 Pathway Signaling Drives an Inflammatory Phenotype in Group A Ependymoma. Cancer immunology research. vol 3. issue 10. 2016-07-19. PMID:25968456. |
epn tumor cell growth was shown to be dependent on stat3 activity, as demonstrated using shrna knockdown and pharmacologic inhibition of stat3 that blocked proliferation and induced apoptosis. |
2016-07-19 |
2023-08-13 |
Not clear |
| Charlotte E Egan, Chhinder P Sodhi, Misty Good, Joyce Lin, Hongpeng Jia, Yukihiro Yamaguchi, Peng Lu, Congrong Ma, Maria F Branca, Samantha Weyandt, William B Fulton, Diego F Niño, Thomas Prindle, John A Ozolek, David J Hacka. Toll-like receptor 4-mediated lymphocyte influx induces neonatal necrotizing enterocolitis. The Journal of clinical investigation. vol 126. issue 2. 2016-07-08. PMID:26690704. |
th17 lymphocytes were required for nec development, as inhibition of stat3 or il-17 receptor signaling attenuated nec in mice, while il-17 release impaired enterocyte tight junctions, increased enterocyte apoptosis, and reduced enterocyte proliferation, leading to nec. |
2016-07-08 |
2023-08-13 |
mouse |
| Xiao-hu Nie, Jia Ou-yang, Ying Xing, Dan-yan Li, Xing-yu Dong, Ru-en Liu, Ru-xiang X. Paeoniflorin inhibits human glioma cells via STAT3 degradation by the ubiquitin-proteasome pathway. Drug design, development and therapy. vol 9. 2016-07-06. PMID:26508835. |
these findings indicated that pf-induced growth suppression and apoptosis in human glioma cells through the proteasome-dependent degradation of stat3. |
2016-07-06 |
2023-08-13 |
human |
| Xing-Hua Liao, Li Zheng, Hong-Peng He, De-Liang Zheng, Zhao-Qiang Wei, Nan Wang, Jian Dong, Wen-Jian Ma, Tong-Cun Zhan. STAT3 regulated ATR via microRNA-383 to control DNA damage to affect apoptosis in A431 cells. Cellular signalling. vol 27. issue 11. 2016-06-30. PMID:26261078. |
stat3 regulated atr via microrna-383 to control dna damage to affect apoptosis in a431 cells. |
2016-06-30 |
2023-08-13 |
human |
| Yoon Mee Yang, Chan Gyu Lee, Ja Hyun Koo, Tae Hyun Kim, Jung Min Lee, Jihyun An, Kang Mo Kim, Sang Geon Ki. Gα12 overexpressed in hepatocellular carcinoma reduces microRNA-122 expression via HNF4α inactivation, which causes c-Met induction. Oncotarget. vol 6. issue 22. 2016-06-28. PMID:25965999. |
mir-122 mimic transfection diminished the ability of gα12 to increase c-met and to activate erk, stat3, and akt/mtor, suppressing cell proliferation with augmented apoptosis. |
2016-06-28 |
2023-08-13 |
human |