| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Seung Ho Baek, Jeong-Hyeon Ko, Hanwool Lee, Jinhong Jung, Moonkyoo Kong, Jung-woo Lee, Junhee Lee, Arunachalam Chinnathambi, M E Zayed, Sulaiman Ali Alharbi, Seok-Geun Lee, Bum Sang Shim, Gautam Sethi, Sung-Hoon Kim, Woong Mo Yang, Jae-Young Um, Kwang Seok Ah. Resveratrol inhibits STAT3 signaling pathway through the induction of SOCS-1: Role in apoptosis induction and radiosensitization in head and neck tumor cells. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 23. issue 5. 2016-10-21. PMID:27064016. |
resveratrol inhibits stat3 signaling pathway through the induction of socs-1: role in apoptosis induction and radiosensitization in head and neck tumor cells. |
2016-10-21 |
2023-08-13 |
Not clear |
| Joohyun Lee, Min Kyung Jung, Hyun Jeong Park, Kyung Eun Kim, Daeho Ch. Erdr1 Suppresses Murine Melanoma Growth via Regulation of Apoptosis. International journal of molecular sciences. vol 17. issue 1. 2016-10-20. PMID:26784177. |
additionally, erdr1 downregulated stat3 activity, inhibiting apoptosis via regulation of the bcl-2 family. |
2016-10-20 |
2023-08-13 |
mouse |
| Seung Ho Baek, Jae Hwi Lee, Jeong-Hyeon Ko, Hanwool Lee, Dongwoo Nam, Seok Geun Lee, Woong Mo Yang, Jae-Young Um, Junhee Lee, Sung-Hoon Kim, Bum Sang Shim, Kwang Seok Ah. Ginkgetin Blocks Constitutive STAT3 Activation and Induces Apoptosis through Induction of SHP-1 and PTEN Tyrosine Phosphatases. Phytotherapy research : PTR. vol 30. issue 4. 2016-10-20. PMID:27059688. |
ginkgetin blocks constitutive stat3 activation and induces apoptosis through induction of shp-1 and pten tyrosine phosphatases. |
2016-10-20 |
2023-08-13 |
Not clear |
| Teng-Fei Fan, Lin-Lin Bu, Wei-Ming Wang, Si-Rui Ma, Jian-Feng Liu, Wei-Wei Deng, Liang Mao, Guang-Tao Yu, Cong-Fa Huang, Bing Liu, Wen-Feng Zhang, Zhi-Jun Su. Tumor growth suppression by inhibiting both autophagy and STAT3 signaling in HNSCC. Oncotarget. vol 6. issue 41. 2016-10-11. PMID:26561201. |
the pharmacological or genetic inhibition of autophagy and stat3 further sensitized hnscc cells to apoptosis. |
2016-10-11 |
2023-08-13 |
human |
| Yan Yang, Shiyu Song, Haiyan Min, Xiufang Chen, Qian Ga. STAT3 degradation mediated by calcineurin involved in the neurotoxicity of isoflurane. Neuroreport. vol 27. issue 2. 2016-10-06. PMID:26694943. |
we found that inhibiting the activity of calcineurin, which specifically promotes stat3 degradation, alleviated isoflurane-induced neural apoptosis. |
2016-10-06 |
2023-08-13 |
mouse |
| David S Rowlands, Andre R Nelson, Frederic Raymond, Sylviane Metairon, Robert Mansourian, Jim Clarke, Trent Stellingwerff, Stuart M Phillip. Protein-leucine ingestion activates a regenerative inflammo-myogenic transcriptome in skeletal muscle following intense endurance exercise. Physiological genomics. vol 48. issue 1. 2016-10-05. PMID:26508702. |
by 240 min, the protein-leucine transcriptome was anti-inflammatory and promyogenic (il-6, nf- β, smad, stat3 network inhibition), with overrepresented functions including decreased leukocyte migration and connective tissue development (-1.8-2.4, p < 0.01), increased apoptosis of myeloid and muscle cells (2.2-3.0, p < 0.002), and cell metabolism (2.0-2.4, p < 0.01). |
2016-10-05 |
2023-08-13 |
Not clear |
| Chulwon Kim, Sang Hyun Baek, Jae-Young Um, Bum Sang Shim, Kwang Seok Ah. Resveratrol attenuates constitutive STAT3 and STAT5 activation through induction of PTPε and SHP-2 tyrosine phosphatases and potentiates sorafenib-induced apoptosis in renal cell carcinoma. BMC nephrology. vol 17. 2016-10-05. PMID:26911335. |
resveratrol attenuates constitutive stat3 and stat5 activation through induction of ptpε and shp-2 tyrosine phosphatases and potentiates sorafenib-induced apoptosis in renal cell carcinoma. |
2016-10-05 |
2023-08-13 |
Not clear |
| Sun Mi Kwon, Yu Yeon Jung, Chul Ju Hwang, Mi Hee Park, Na Young Yoon, Tae Myung Kim, Ji Myung Yu, Dae Hwan Kim, Doo Won Seo, Hyu Seok Youn, Hyun Ok Seo, In Sung Chung, Sang Bae Han, Bang Yeon Hwang, Hwan-Soo Yoo, Jae-Kyung Jung, Heesoon Lee, Jin Tae Hon. Anti-cancer effect of N-(3,5-bis(trifluoromethyl)phenyl)-5-chloro-2,3-dihydronaphtho[1,2-b]furan-2-carboxamide, a novel synthetic compound. Molecular carcinogenesis. vol 55. issue 5. 2016-09-21. PMID:25865242. |
nhdc also induced expression of the apoptosis regulating genes as well as inhibiting the action of stat3. |
2016-09-21 |
2023-08-13 |
Not clear |
| Sadeesh Em, Fozia Shah, P S Yada. Differential developmental competence and gene expression patterns in buffalo (Bubalus bubalis) nuclear transfer embryos reconstructed with fetal fibroblasts and amnion mesenchymal stem cells. Cytotechnology. vol 68. issue 5. 2016-09-16. PMID:26660476. |
alterations in the expression pattern of genes implicated in transcription and pluripotency (oct4, stat3, nanog), dna methylation (dnmt1, dnmt3a), histone deacetylation (hdac2), growth factor signaling and imprinting (igf2, igf2r), apoptosis (bax, bcl2), metabolism (glut1) and oxidative stress (mnsod) regulation were observed in cloned embryos. |
2016-09-16 |
2023-08-13 |
Not clear |
| W Ruoming, Y Zhen, Z Tengteng, H Jishen. Tumor suppressor microRNA-31 inhibits gastric carcinogenesis by targeting Smad4 and SGPP2. Cancer gene therapy. vol 22. issue 12. 2016-09-13. PMID:26494556. |
functional studies showed that increasing mir-31 inhibited gc cell proliferation, promoted apoptosis and attenuated cell migration, which were also linked to downregulation of stat3. |
2016-09-13 |
2023-08-13 |
mouse |
| W Ruoming, Y Zhen, Z Tengteng, H Jishen. Tumor suppressor microRNA-31 inhibits gastric carcinogenesis by targeting Smad4 and SGPP2. Cancer gene therapy. vol 22. issue 12. 2016-09-13. PMID:26494556. |
this study has revealed mir-31 as a tumor suppressor and has identified sgpp2 and smad4 as novel targets of mir-31, linking to stat3 for regulating cancer cell proliferation, apoptosis and migration in gc. |
2016-09-13 |
2023-08-13 |
mouse |
| J Zhou, Z Ning, B Wang, E-J Yun, T Zhang, R-C Pong, L Fazli, M Gleave, J Zeng, J Fan, X Wang, L Li, J-T Hsieh, D He, K W. DAB2IP loss confers the resistance of prostate cancer to androgen deprivation therapy through activating STAT3 and inhibiting apoptosis. Cell death & disease. vol 6. 2016-09-13. PMID:26512963. |
dab2ip loss confers the resistance of prostate cancer to androgen deprivation therapy through activating stat3 and inhibiting apoptosis. |
2016-09-13 |
2023-08-13 |
mouse |
| J Zhou, Z Ning, B Wang, E-J Yun, T Zhang, R-C Pong, L Fazli, M Gleave, J Zeng, J Fan, X Wang, L Li, J-T Hsieh, D He, K W. DAB2IP loss confers the resistance of prostate cancer to androgen deprivation therapy through activating STAT3 and inhibiting apoptosis. Cell death & disease. vol 6. 2016-09-13. PMID:26512963. |
moreover, the luminal epithelia in dab2ip(-/-) mice with more activated stat3 and survivin expression were resistant to castration-induced apoptosis. |
2016-09-13 |
2023-08-13 |
mouse |
| Nanmu Yang, Feng Han, Hong Cui, Jinxi Huang, Tao Wang, Yi Zhou, Jinxue Zho. Matrine suppresses proliferation and induces apoptosis in human cholangiocarcinoma cells through suppression of JAK2/STAT3 signaling. Pharmacological reports : PR. vol 67. issue 2. 2016-09-06. PMID:25712669. |
constitutive activation of signal transducer and activator of transcription 3 (stat3) signaling contributes to apoptosis resistance in cholangiocarcinoma. |
2016-09-06 |
2023-08-13 |
human |
| Hye-Sook Seo, Jae Kyung Jo, Jin Mo Ku, Han-Seok Choi, Youn Kyung Choi, Jong-Kyu Woo, Hyo In Kim, Soo-Yeon Kang, Kang Min Lee, Koong Won Nam, Namkyu Park, Bo-Hyoung Jang, Yong Cheol Shin, Seong-Gyu K. Induction of caspase-dependent extrinsic apoptosis by apigenin through inhibition of signal transducer and activator of transcription 3 (STAT3) signalling in HER2-overexpressing BT-474 breast cancer cells. Bioscience reports. vol 35. issue 6. 2016-09-06. PMID:26500281. |
induction of caspase-dependent extrinsic apoptosis by apigenin through inhibition of signal transducer and activator of transcription 3 (stat3) signalling in her2-overexpressing bt-474 breast cancer cells. |
2016-09-06 |
2023-08-13 |
Not clear |
| Hye-Sook Seo, Jae Kyung Jo, Jin Mo Ku, Han-Seok Choi, Youn Kyung Choi, Jong-Kyu Woo, Hyo In Kim, Soo-Yeon Kang, Kang Min Lee, Koong Won Nam, Namkyu Park, Bo-Hyoung Jang, Yong Cheol Shin, Seong-Gyu K. Induction of caspase-dependent extrinsic apoptosis by apigenin through inhibition of signal transducer and activator of transcription 3 (STAT3) signalling in HER2-overexpressing BT-474 breast cancer cells. Bioscience reports. vol 35. issue 6. 2016-09-06. PMID:26500281. |
our study indicates that apigenin induces apoptosis through inhibition of stat3 signalling and could serve as a useful compound to prevent or treat her2-overexpressing breast cancer. |
2016-09-06 |
2023-08-13 |
Not clear |
| Tiezhu Zhou, Yang Yang, Hongyan Zhang, Yuqin Che, Wei Wang, Hui Lv, Jie Li, Yuanyuan Wang, Shuai Ho. Serenoa Repens Induces Growth Arrest, Apoptosis and Inactivation of STAT3 Signaling in Human Glioma Cells. Technology in cancer research & treatment. vol 14. issue 6. 2016-09-02. PMID:24945373. |
serenoa repens induces growth arrest, apoptosis and inactivation of stat3 signaling in human glioma cells. |
2016-09-02 |
2023-08-13 |
human |
| Ying Sun, Bao-feng Guo, Li-bo Xu, Jia-teng Zhong, Zhe-wen Liu, Hang Liang, Nai-yan Wen, Wen-jing Yun, Ling Zhang, Xue-jian Zha. Stat3-siRNA inhibits the growth of gastric cancer in vitro and in vivo. Cell biochemistry and function. vol 33. issue 7. 2016-08-26. PMID:26486443. |
in the present study, we constructed a psi-stat3 plasmid to silence stat3 and investigated the effect of psi-stat3 on cell proliferation, apoptosis and cell cycle progression in gastric cancer cell line sgc-7901 and mice xenograft model. |
2016-08-26 |
2023-08-13 |
mouse |
| Ying Sun, Bao-feng Guo, Li-bo Xu, Jia-teng Zhong, Zhe-wen Liu, Hang Liang, Nai-yan Wen, Wen-jing Yun, Ling Zhang, Xue-jian Zha. Stat3-siRNA inhibits the growth of gastric cancer in vitro and in vivo. Cell biochemistry and function. vol 33. issue 7. 2016-08-26. PMID:26486443. |
it showed that psi-stat3 can effectively silence the expression of stat3 and inhibits the growth of gastric tumour both in vitro and in vivo significantly via cell apoptosis and cell cycle shift induction. |
2016-08-26 |
2023-08-13 |
mouse |
| L-X Zhong, Y Zhang, M-L Wu, Y-N Liu, P Zhang, X-Y Chen, Q-Y Kong, J Liu, H L. Resveratrol and STAT inhibitor enhance autophagy in ovarian cancer cells. Cell death discovery. vol 2. 2016-08-23. PMID:27551495. |
resveratrol efficiently suppressed growth, induced apoptosis and inactivated stat3 signaling of the two oc cell lines. |
2016-08-23 |
2023-08-13 |
Not clear |