| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ying Sun, Liming Fan, Yixian L. Low expression of LncRNA AFAP1-AS1 inhibits proliferation and promotes apoptosis of non-small cell lung cancer cells through inhibiting wnt signaling pathway. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 12. 2023-12-08. PMID:38063100. |
low expression of lncrna afap1-as1 inhibits proliferation and promotes apoptosis of non-small cell lung cancer cells through inhibiting wnt signaling pathway. |
2023-12-08 |
2023-12-17 |
Not clear |
| Ying Sun, Liming Fan, Yixian L. Low expression of LncRNA AFAP1-AS1 inhibits proliferation and promotes apoptosis of non-small cell lung cancer cells through inhibiting wnt signaling pathway. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 12. 2023-12-08. PMID:38063100. |
lowly-expressed afap1-as1 inhibits the proliferation and promotes the apoptosis of nsclc a549 cells via inhibiting the wnt signaling pathway. |
2023-12-08 |
2023-12-17 |
Not clear |
| Sweety Mehra, Aitizaz Ul Ahsan, Madhu Sharma, Muskan Budhwar, Mani Chopr. Gestational Fisetin Exerts Neuroprotection by Regulating Mitochondria-Directed Canonical Wnt Signaling, BBB Integrity, and Apoptosis in Prenatal VPA-Induced Rodent Model of Autism. Molecular neurobiology. 2023-12-04. PMID:38048031. |
gestational fisetin exerts neuroprotection by regulating mitochondria-directed canonical wnt signaling, bbb integrity, and apoptosis in prenatal vpa-induced rodent model of autism. |
2023-12-04 |
2023-12-10 |
Not clear |
| Sweety Mehra, Aitizaz Ul Ahsan, Madhu Sharma, Muskan Budhwar, Mani Chopr. Gestational Fisetin Exerts Neuroprotection by Regulating Mitochondria-Directed Canonical Wnt Signaling, BBB Integrity, and Apoptosis in Prenatal VPA-Induced Rodent Model of Autism. Molecular neurobiology. 2023-12-04. PMID:38048031. |
vpa induced mitochondrial damage and over-activated the canonical wnt signaling which further increased the blood-brain barrier (bbb) disruption, apoptosis, and neuronal damage. |
2023-12-04 |
2023-12-10 |
Not clear |
| Jeong-Hun Kang, Takahito Kawano, Masaharu Murata, Riki Toit. Vascular calcification and cellular signaling pathways as potential therapeutic targets. Life sciences. 2023-12-02. PMID:38042282. |
various cellular signaling pathways are associated with vc, including the wnt, mitogen-activated protein kinase, phosphatidylinositol-3 kinase/akt, cyclic nucleotide-dependent protein kinase, protein kinase c, calcium/calmodulin-dependent kinase ii, adenosine monophosphate-activated protein kinase/mammalian target of rapamycin, ras homologous gtpase, apoptosis, notch, and cytokine signaling pathways. |
2023-12-02 |
2023-12-10 |
Not clear |
| Jiawen Yang, James T Lim, Paul Victor, Chen Chen, Hunain Khwaja, Rick G Schnellmann, Denise J Roe, Prafulla C Gokhale, James A DeCaprio, Megha Pad. Integrative analysis reveals therapeutic potential of pyrvinium pamoate in Merkel cell carcinoma. bioRxiv : the preprint server for biology. 2023-11-14. PMID:37961132. |
specifically, pyrvinium not only reverses the neuroendocrine features of mcc by modulating canonical and non-canonical wnt signaling pathways but also inhibits cancer cell growth by activating the p53-mediated apoptosis pathway, disrupting mitochondrial function, and inducing endoplasmic reticulum (er) stress. |
2023-11-14 |
2023-11-20 |
mouse |
| Ling Lei, Guangxi Peng, Hongliang Luo, Wugen L. SRY-box transcription factor 21 antisense divergent transcript 1: Regulatory roles and clinical significance in neoplastic conditions and Alzheimer's Disease. Journal of Cancer. vol 14. issue 17. 2023-11-06. PMID:37928430. |
it influences neuronal viability, apoptosis, and oxidative stress by interacting with mir-107 and mir-132, and affecting the pi3k/akt and wnt signaling pathways. |
2023-11-06 |
2023-11-08 |
Not clear |
| Ruchi Jakhmola Mani, Nitu Dogra, Deepshikha Pande Katar. The Connection between Chronic Liver Damage and Sporadic Alzheimer's Disease: Evidence and Insights from a Rat Model. Brain sciences. vol 13. issue 10. 2023-10-30. PMID:37891760. |
bioinformatics analysis on serum protein suggests a few affected molecular pathways, like the amyloid secretase pathway, androgen/oestrogen/progesterone biosynthesis, the apoptosis signalling pathway, the insulin/igf pathway-protein kinase b signalling cascade, the metabotropic glutamate receptor group i pathway, the wnt signalling pathway, etc. |
2023-10-30 |
2023-11-08 |
rat |
| Haibo Yang, Yaying Zhao, Wei Song, Guoqiang Fa. The inhibition of β-catenin activity by luteolin isolated from Paulownia flowers leads to growth arrest and apoptosis in cholangiocarcinoma. International journal of biological macromolecules. 2023-10-26. PMID:37884243. |
luteolin inhibits the activity of the wnt signaling, causing cholangiocarcinoma (cca) cell cycle arrest in the g2/m phase, leading to cell apoptosis and inhibition of cell migration. |
2023-10-26 |
2023-11-08 |
Not clear |
| Yuanqing Cai, Huijun Sun, Xingyu Song, Jianyu Zhao, Dong Xu, Mozhen Li. The Wnt/β-catenin signaling pathway inhibits osteoporosis by regulating the expression of TERT: an Aging. vol 15. 2023-10-20. PMID:37862118. |
the wnt/β-catenin signaling pathway inhibits osteoporosis by regulating the expression of tert: an our study was performed to investigate whether the wingless and int-1 (wnt) signaling pathway promotes osteogenic differentiation and inhibits apoptosis in bone marrow mesenchymal stem cells (bmscs) by regulating telomerase reverse transcriptase (tert) expression. |
2023-10-20 |
2023-11-08 |
Not clear |
| Rui Guo, Yiran Zhou Guo, Qing Zhou, Guoju Li, Zhanghui Du, Yefei Shi, Quansheng Xin. ROR2 deficit may induce the tetralogy of Fallot via down-regulating of β-catenin/SOX3/HSPA6 in vitro and in vivo. Journal of cellular and molecular medicine. 2023-09-26. PMID:37749917. |
kegg analysis and go analysis of the differentially expressed genes indicated that these genes were significantly enriched in the wnt signalling pathway, apoptosis and cardiac development function. |
2023-09-26 |
2023-10-07 |
human |
| Lovedeep Singh, Rajbir Bhatt. Signaling Pathways Involved in the Neuroprotective Effect of Osthole: Evidence and Mechanisms. Molecular neurobiology. 2023-09-08. PMID:37682453. |
activation of wnt by osthole, in turn, regulates downstream gsk-1β to inhibit tau phosphorylation and β-catenin degradation to prevent neuronal apoptosis. |
2023-09-08 |
2023-10-07 |
human |
| YunFeng Long, Yong Luo, Liu Hu, Hong Liao, Jin Li. Targeting miR-146b-5p to Regulate KDM6B Expression Aggravates Bronchopulmonary Dysplasia. Molecular biotechnology. 2023-08-16. PMID:37584827. |
mir-146b-5p activates the wnt pathway through targeted regulation of kdm6b, thereby aggravating hyperoxia-induced inflammation and apoptosis of lung epithelial cells. |
2023-08-16 |
2023-09-07 |
mouse |
| Faezeh Tolue Ghasaban, Amirhosein Maharati, Amir Sadra Zangouei, Alireza Zangooie, Meysam Moghbel. MicroRNAs as the pivotal regulators of cisplatin resistance in head and neck cancers. Cancer cell international. vol 23. issue 1. 2023-08-16. PMID:37587481. |
it has been reported that the mirnas exerted their roles in cddp response by regulation of signaling pathways such as wnt, notch, pi3k/akt, tgf-β, and nf-kb as well as apoptosis, autophagy, and emt process. |
2023-08-16 |
2023-09-07 |
Not clear |
| Mahammad Ghouse Shaik, Swanand Vinayak Joshi, Ravikumar Akunuri, Preeti Rana, Ziaur Rahman, Anusha Polomoni, Venkata Madhavi Yaddanapudi, Manoj P Dandekar, Nanduri Sriniva. Small molecule inhibitors of NLRP3 inflammasome and GSK-3β in the management of traumatic brain injury: A review. European journal of medicinal chemistry. vol 259. 2023-08-13. PMID:37573828. |
similarly, gsk-3β regulates apoptosis through tyrosine kinase and canonical wnt signalling pathways. |
2023-08-13 |
2023-08-16 |
Not clear |
| Rinki Doloi, Sadhana M Gupt. MicroRNAs: The key players regulating the crosstalk between Hippo and Wnt/β-catenin pathways in breast cancer. Life sciences. 2023-07-29. PMID:37516428. |
the hippo signalling and wnt signalling pathways were identified as important signal transducers involved in maintaining organ development, tissue homeostasis, cell proliferation and apoptosis. |
2023-07-29 |
2023-08-14 |
Not clear |
| Jun Du, Yingquan Zhuo, Xu Sun, Meilan Nie, Jiafei Yang, Xi Luo, Huajian G. hsa_circ_0000285 sponging miR-582-3p promotes neuroblastoma progression by regulating the Wnt/β-catenin signaling pathway. Open medicine (Warsaw, Poland). vol 18. issue 1. 2023-07-19. PMID:37465351. |
the expression of proteins associated with apoptosis (bax and bcl-2) and the proteins associated with wnt/β-catenin (wnt, p-gsk-3β, gsk-3β, β-catenin, and c-myc) were quantified by western blotting. |
2023-07-19 |
2023-08-14 |
Not clear |
| B S Soumya, V P Shreenidhi, Apoorvaa Agarwal, Rajesh Kumar Gandhirajan, Arun Dharmarajan, Sudha Warrie. Unwinding the role of Wnt signaling cascade and molecular triggers of motor neuron degeneration in amyotrophic lateral sclerosis (ALS). Cellular signalling. 2023-07-18. PMID:37463628. |
this review discusses the role of wnt signaling in the reported causes of als such as oxidative stress, mitochondrial dysfunction, autophagy, and apoptosis. |
2023-07-18 |
2023-08-14 |
Not clear |
| Li Li, Yan Liu, Yawei Zheng, Jian Zhu, Dan Wu, Xiaohui Yan, Changyin Li, Minghua Wu, Wenlei L. Exploring the mechanisms under Zuogui Pill's treatment of ischemic stroke through network pharmacology and Frontiers in pharmacology. vol 14. 2023-07-10. PMID:37426810. |
based on pathway enrichment studies, zuogui pill may exert neuroprotection through mapk signaling, pi3k-akt signaling and apoptosis, as well as enhance neurite outgrowth and axonal regeneration effect via mtor signaling, p53 signaling and wnt signaling pathways. |
2023-07-10 |
2023-08-14 |
Not clear |
| Yuri Lee, Hai-Long Piao, Jongchan Ki. OTUD7B Activates Wnt Signaling Pathway through the Interaction with LEF1. Biomolecules. vol 13. issue 6. 2023-06-28. PMID:37371581. |
the wnt signaling pathway plays a critical role in regulating normal cellular processes, including proliferation, differentiation, and apoptosis. |
2023-06-28 |
2023-08-14 |
human |