| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jingyi Sun, Xinxin Shao, Jinying Huang, Mengxin Gong, Jianyong Zhang, Zuoqing Yua. Multiple toxicity evaluations of perfluorooctane sulfonate on intact planarian Dugesia japonica. Environmental science and pollution research international. 2023-04-12. PMID:37042918. |
the proliferation of neoblasts, apoptosis, dna damage and the expression levels of neuronal genes and the major genes of the wnt pathway were effectively studied. |
2023-04-12 |
2023-08-14 |
Not clear |
| Wenting Zhuang, Tong Ye, Wei Wang, Weihong Song, Tao Ta. CTNNB1 in neurodevelopmental disorders. Frontiers in psychiatry. vol 14. 2023-04-03. PMID:37009120. |
mutations of ctnnb1 lead to the dysfunction of the wnt signaling pathway that regulates gene transcription and further disturbs synaptic plasticity, neuronal apoptosis, and neurogenesis. |
2023-04-03 |
2023-08-14 |
Not clear |
| Ajay Kumar, Bunty Sharma, Ujjawal Sharma, Gaurav Parashar, Nidarshana Chaturvedi Parashar, Isha Rani, Seema Ramniwas, Satwinderjeet Kaur, Shafiul Haque, Hardeep Singh Tul. Apoptotic and antimetastatic effect of cucurbitacins in cancer: recent trends and advancement. Naunyn-Schmiedeberg's archives of pharmacology. 2023-04-03. PMID:37010571. |
the jak-stat3, wnt, pi3k/akt, and mapk signaling pathways, which are essential for the survival and apoptosis of cancer cells, have also been shown to be suppressed by cucurbitacins. |
2023-04-03 |
2023-08-14 |
Not clear |
| Alberto Losada-García, Iván Salido-Guadarrama, Sergio Alberto Cortes-Ramirez, Marian Cruz-Burgos, Miguel Morales-Pacheco, Karla Vazquez-Santillan, Griselda Rodriguez-Martinez, Imelda González-Ramírez, Vanessa Gonzalez-Covarrubias, Carlos Perez-Plascencia, Mauricio Rodríguez-Dorante. SFRP1 induces a stem cell phenotype in prostate cancer cells. Frontiers in cell and developmental biology. vol 11. 2023-03-27. PMID:36968194. |
the wnt pathway is involved in processes such as cell proliferation, differentiation, cell anchoring, apoptosis, and cell cycle regulation as well as the regulation of stem cell populations in the prostatic epithelium. |
2023-03-27 |
2023-08-14 |
Not clear |
| Anja Tursch, Thomas W Holstei. From injury to patterning-MAPKs and Wnt signaling in Hydra. Current topics in developmental biology. vol 153. 2023-03-26. PMID:36967201. |
however, the early wnt genes are activated by mapk signaling rather than apoptosis. |
2023-03-26 |
2023-08-14 |
Not clear |
| Michael Bordonar. Oncogenic and Receptor-Mediated Wnt Signaling Influence the Sensitivity of Colonic Cells to Butyrate. Journal of Cancer. vol 14. issue 3. 2023-03-02. PMID:36860917. |
dietary fiber is protective against crc and this activity is likely mediated by butyrate, a breakdown product of dietary fiber that hyperactivates wnt signaling, repressing crc proliferation and inducing apoptosis. |
2023-03-02 |
2023-08-14 |
Not clear |
| Jing Yang, Xuejun Ko. Endonuclease G promotes preeclampsia by regulating the Wnt signaling pathway. Autoimmunity. vol 56. issue 1. 2023-02-28. PMID:36852641. |
endog expression was upregulated in preeclampsia and affected htr-8/svneo cell proliferation, invasion, migration, apoptosis, and angiogenesis via the wnt signaling pathway. |
2023-02-28 |
2023-08-14 |
Not clear |
| Yan Jiang, Xiahao Zhao, Jin Chen, Stanley Aniagu, Tao Che. PM2.5 induces cardiac malformations via PI3K/akt2/mTORC1 signaling pathway in zebrafish larvae. Environmental pollution (Barking, Essex : 1987). 2023-02-22. PMID:36804889. |
we further demonstrated that mtorc1 phosphorylation mediates the adverse effects of akt2 on intrinsic apoptosis and canonical wnt signaling in the heart of zebrafish larvae exposed to eom. |
2023-02-22 |
2023-08-14 |
zebrafish |
| Yan Jiang, Xiahao Zhao, Jin Chen, Stanley Aniagu, Tao Che. PM2.5 induces cardiac malformations via PI3K/akt2/mTORC1 signaling pathway in zebrafish larvae. Environmental pollution (Barking, Essex : 1987). 2023-02-22. PMID:36804889. |
in conclusion, our results indicate that pm2.5 activates pi3k/akt2/mtorc1 signaling via ahr/ros-induced pten suppression, which leads to mitochondrial-mediated intrinsic apoptosis and wnt signaling suppression, resulting in cardiac defects in zebrafish larvae. |
2023-02-22 |
2023-08-14 |
zebrafish |
| Pnina Fishman, Salomon M Stemmer, Avital Bareket-Samish, Michael H Silverman, William D Kern. Targeting the A3 adenosine receptor to treat hepatocellular carcinoma: anti-cancer and hepatoprotective effects. Purinergic signalling. 2023-02-13. PMID:36781824. |
namodenoson, an a3ar agonist, induces de-regulation of the wnt and nf-kb signaling pathways resulting in apoptosis of hcc cells. |
2023-02-13 |
2023-08-14 |
human |
| Fangfang Zhuo, Shuang Luo, Wei He, Zhanhui Feng, Ya'nan Hu, Jingxia Xu, Zejun Wang, Jianwei X. The Role of Signaling Pathways in Pancreatic Cancer Targeted Therapy. American journal of clinical oncology. 2023-02-03. PMID:36735511. |
many studies have shown that signaling pathways perform a function in the occurrence and development of pc, for instance, phosphoinositide 3-kinase (pi3k)/akt, nuclear factor-κb, ras, interleukin (il)-17b/il-17rb, wnt, and hepatocyte growth factor/c-met, which play roles in the proliferation, metastasis, invasion, inhibition of apoptosis, promotion of angiogenesis, and drug resistance of pc. |
2023-02-03 |
2023-08-14 |
Not clear |
| Mehrdad Hashemi, Sahar Hasani, Shima Hajimazdarany, Fatemeh Ghadyani, Yeganeh Olyaee, Marzieh Khodadadi, Maryam Fallah Ziyarani, Amir Dehghanpour, Hasti Salehi, Amirabbas Kakavand, Mohammad Ali Shekhi Beig Goharrizi, Amir Reza Aref, Shokooh Salimimoghadam, Mohammad Esmaeil Akbari, Afshin Taheriazam, Kiavash Hushmandi, Maliheh Entezar. Biological functions and molecular interactions of Wnt/β-catenin in breast cancer: Revisiting signaling networks. International journal of biological macromolecules. 2023-01-26. PMID:36702226. |
the upregulation of wnt is commonly observed during progression of breast tumor and confirms that tumor cells are dependent on this pathway wnt/β-catenin induction prevents apoptosis that is of importance for mediating drug resistance. |
2023-01-26 |
2023-08-14 |
Not clear |
| Yao Wang, Jing He, Junwei Zhang, Nihui Zhang, Yong Zhou, Fang W. Cell migration induces apoptosis in osteosarcoma cell via inhibition of Wnt-β-catenin signaling pathway. Colloids and surfaces. B, Biointerfaces. vol 223. 2023-01-20. PMID:36669438. |
to this aim, we have prepared rgd-modified substrates to regulate cell motility through modification of rgd with different concentrations, and systematically examined the effect of motility on the apoptosis of tumor cells, and the potential involvement of wnt signaling pathway. |
2023-01-20 |
2023-08-14 |
Not clear |
| Yao Wang, Jing He, Junwei Zhang, Nihui Zhang, Yong Zhou, Fang W. Cell migration induces apoptosis in osteosarcoma cell via inhibition of Wnt-β-catenin signaling pathway. Colloids and surfaces. B, Biointerfaces. vol 223. 2023-01-20. PMID:36669438. |
further rna sequence study strongly suggested that low motility inhibited the canonical wnt signaling pathway, which in turn led to the activation of the mitochondria-associated caspase signaling pathway, and ultimately to the apoptosis of osteosarcoma cells. |
2023-01-20 |
2023-08-14 |
Not clear |
| Yao Wang, Jing He, Junwei Zhang, Nihui Zhang, Yong Zhou, Fang W. Cell migration induces apoptosis in osteosarcoma cell via inhibition of Wnt-β-catenin signaling pathway. Colloids and surfaces. B, Biointerfaces. vol 223. 2023-01-20. PMID:36669438. |
activation of the wnt-β-catenin pathway through hly78 significantly suppressed the apoptosis of mg-63 cells, further suggesting the critical role of wnt pathway in motility-regulated-apoptosis of tumor cells. |
2023-01-20 |
2023-08-14 |
Not clear |
| Jie Huang, Jia-Xin Li, Lin-Rui Ma, Dong-Han Xu, Peng Wang, Li-Qi Li, Li-Li Yu, Yu Li, Run-Ze Li, Hao Zhang, Yu-Hong Zheng, Ling Tang, Pei-Yu Ya. Traditional Herbal Medicine: A Potential Therapeutic Approach for Adjuvant Treatment of Non-small Cell Lung Cancer in the Future. Integrative cancer therapies. vol 21. 2022-12-26. PMID:36567455. |
it emphasizes that, by mainly regulating the p13k/akt signaling pathway, the wnt signaling pathway, and the nf-κb signaling pathway, herbal medicine induces apoptosis and inhibits the proliferation and migration of tumor cells. |
2022-12-26 |
2023-08-14 |
Not clear |
| Mir Hilal Ahmad, Balaram Ghosh, Moshahid Alam Rizvi, Mansoor Ali, Loveleena Kaur, Amal Chandra Monda. Neural crest cells development and neuroblastoma progression: Role of Wnt signaling. Journal of cellular physiology. 2022-12-11. PMID:36502519. |
inhibiting the wnt signaling pathway or its ligands/receptors induces apoptosis and abrogates proliferation and tumorigenicity in all major types of nb cells. |
2022-12-11 |
2023-08-14 |
Not clear |
| Sherif A El-Kafrawy, Mai M El-Daly, Leena H Bajrai, Thamir A Alandijany, Arwa A Faizo, Mohammad Mobashir, Sunbul S Ahmed, Sarfraz Ahmed, Shoaib Alam, Raja Jeet, Mohammad Amjad Kamal, Syed Tauqeer Anwer, Bushra Khan, Manal Tashkandi, Moshahid A Rizvi, Esam Ibraheem Azha. Genomic profiling and network-level understanding uncover the potential genes and the pathways in hepatocellular carcinoma. Frontiers in genetics. vol 13. 2022-12-08. PMID:36479247. |
pi3k, camp, tgf, tnf, rap1, nf-kb, apoptosis, longevity regulating pathway, signaling pathways regulating pluripotency of stem cells, cytokine-cytokine receptor interaction, p53 signaling, wnt signaling, toll-like receptor signaling, and hippo signaling pathways are just a few of the most commonly enriched pathways. |
2022-12-08 |
2023-08-14 |
human |
| Ruchi Shah, Cynthia Amador, Steven T Chun, Sean Ghiam, Mehrnoosh Saghizadeh, Andrei A Kramerov, Alexander V Ljubimo. Non-canonical Wnt signaling in the eye. Progress in retinal and eye research. 2022-11-28. PMID:36443219. |
wnt signaling comprises a group of complex signal transduction pathways that play critical roles in cell proliferation, differentiation, and apoptosis during development, as well as in stem cell maintenance and adult tissue homeostasis. |
2022-11-28 |
2023-08-14 |
Not clear |
| Laury Amelia Roa Fuentes, Marjoen Bloemen, Carine El Carels, Frank Adtg Wagener, Johannes W Von den Hof. Retinoic acid effects on in vitro palatal fusion and WNT signaling. European journal of oral sciences. 2022-10-28. PMID:36303276. |
apoptosis, proliferation, wnt signaling and bone formation were analyzed by histology and quantitative pcr. |
2022-10-28 |
2023-08-14 |
mouse |