| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gemma McGregor, Andrew J Irving, Jenni Harve. Canonical JAK-STAT signaling is pivotal for long-term depression at adult hippocampal temporoammonic-CA1 synapses. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 31. issue 8. 2017-10-10. PMID:28461339. |
canonical jak-stat signaling is pivotal for long-term depression at adult hippocampal temporoammonic-ca1 synapses. |
2017-10-10 |
2023-08-13 |
Not clear |
| Gemma McGregor, Andrew J Irving, Jenni Harve. Canonical JAK-STAT signaling is pivotal for long-term depression at adult hippocampal temporoammonic-CA1 synapses. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 31. issue 8. 2017-10-10. PMID:28461339. |
recent studies identified a crucial role for this pathway in activity-dependent long-term depression (ltd) at hippocampal schaffer collateral (sc)-ca1 synapses. |
2017-10-10 |
2023-08-13 |
Not clear |
| Gemma McGregor, Andrew J Irving, Jenni Harve. Canonical JAK-STAT signaling is pivotal for long-term depression at adult hippocampal temporoammonic-CA1 synapses. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 31. issue 8. 2017-10-10. PMID:28461339. |
these data indicate an essential role for canonical jak-stat signaling in activity-dependent ltd at ta-ca1 synapses and provide valuable insight into the role of the ta input in hippocampal synaptic plasticity.-mcgregor, g., irving, a. j., harvey, j. canonical jak-stat signaling is pivotal for long-term depression at adult hippocampal temporoammonic-ca1 synapses. |
2017-10-10 |
2023-08-13 |
Not clear |
| David J Clarke, Jordyn Stuart, Iain S McGregor, Jonathon C Arnol. Endocannabinoid dysregulation in cognitive and stress-related brain regions in the Nrg1 mouse model of schizophrenia. Progress in neuro-psychopharmacology & biological psychiatry. vol 72. 2017-08-30. PMID:27521758. |
nrg1 application to hippocampal slices decreased 2-arachidonoylglycerol (2-ag) signalling and disrupted long-term depression, a form of synaptic plasticity critical to spatial learning. |
2017-08-30 |
2023-08-13 |
mouse |
| Julien Gibon, Nicolas Unsain, Karine Gamache, Rhalena A Thomas, Andres De Leon, Aaron Johnstone, Karim Nader, Philippe Séguéla, Philip A Barke. The X-linked inhibitor of apoptosis regulates long-term depression and learning rate. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 30. issue 9. 2017-08-22. PMID:27189977. |
hippocampal long-term depression (ltd) is an active form of synaptic plasticity that is necessary for consolidation of spatial memory, contextual fear memory, and novelty acquisition. |
2017-08-22 |
2023-08-13 |
mouse |
| Tathagata Sengupta, Rishi Das, Sumantra Chattarj. Chronic but not acute immobilization stress stably enhances hippocampal CA1 metabotropic glutamate receptor dependent Long-Term Depression. Neuroscience letters. vol 633. 2017-07-27. PMID:27663134. |
acute stress has been shown to facilitate but not increase metabotropic glutamate receptor (mglur) mediated long-term depression (ltd) in the hippocampus. |
2017-07-27 |
2023-08-13 |
rat |
| Lanting Huang, Xiu-Juan Yang, Ying Huang, Eve Y Sun, Mu Su. Ketamine Protects Gamma Oscillations by Inhibiting Hippocampal LTD. PloS one. vol 11. issue 7. 2017-07-18. PMID:27467732. |
ketamine protects gamma oscillations by inhibiting hippocampal ltd. nmda receptors have been widely reported to be involved in the regulation of synaptic plasticity through effects on long-term potentiation (ltp) and long-term depression (ltd). |
2017-07-18 |
2023-08-13 |
mouse |
| Xin Wu, Jie-Ting Zhang, Di Li, Jun Zhou, Jun Yang, Hui-Ling Zheng, Jian-Guo Chen, Fang Wan. Aquaporin-4 deficiency facilitates fear memory extinction in the hippocampus through excessive activation of extrasynaptic GluN2B-containing NMDA receptors. Neuropharmacology. vol 112. issue Pt A. 2017-07-11. PMID:27373674. |
therefore, we evaluated long-term depression (ltd) in the hippocampus and the extinction of fear memory of aqp-4 knockout (ko) and wild-type (wt) mice. |
2017-07-11 |
2023-08-13 |
mouse |
| Grace France, Diego Fernández-Fernández, Erica S Burnell, Mark W Irvine, Daniel T Monaghan, David E Jane, Zuner A Bortolotto, Graham L Collingridge, Arturas Volianski. Multiple roles of GluN2B-containing NMDA receptors in synaptic plasticity in juvenile hippocampus. Neuropharmacology. vol 112. issue Pt A. 2017-07-11. PMID:27523302. |
in the ca1 area of the hippocampus n-methyl-d-aspartate receptors (nmdars) mediate the induction of long-term depression (ltd), short-term potentiation (stp) and long-term potentiation (ltp). |
2017-07-11 |
2023-08-13 |
rat |
| Feng Cao, Zikai Zhou, Xingxiu Pan, Celeste Leung, Wei Xie, Graham Collingridge, Zhengping Ji. Developmental regulation of hippocampal long-term depression by cofilin-mediated actin reorganization. Neuropharmacology. vol 112. issue Pt A. 2017-07-11. PMID:27543417. |
developmental regulation of hippocampal long-term depression by cofilin-mediated actin reorganization. |
2017-07-11 |
2023-08-13 |
mouse |
| Feng Cao, Zikai Zhou, Xingxiu Pan, Celeste Leung, Wei Xie, Graham Collingridge, Zhengping Ji. Developmental regulation of hippocampal long-term depression by cofilin-mediated actin reorganization. Neuropharmacology. vol 112. issue Pt A. 2017-07-11. PMID:27543417. |
in this study, we investigate whether the involvement of cofilin in plasticity is developmentally regulated by examining the role of cofilin in hippocampal long-term depression (ltd) in both young (2 weeks) and mature (2 months) mice. |
2017-07-11 |
2023-08-13 |
mouse |
| Birte Dietz, Denise Manahan-Vaugha. Hippocampal long-term depression is facilitated by the acquisition and updating of memory of spatial auditory content and requires mGlu5 activation. Neuropharmacology. vol 115. 2017-07-07. PMID:27055771. |
hippocampal long-term depression is facilitated by the acquisition and updating of memory of spatial auditory content and requires mglu5 activation. |
2017-07-07 |
2023-08-13 |
Not clear |
| Thomas M Sanderson, Ellen L Hogg, Graham L Collingridge, Sonia A L Corrê. Hippocampal metabotropic glutamate receptor long-term depression in health and disease: focus on mitogen-activated protein kinase pathways. Journal of neurochemistry. vol 139 Suppl 2. 2017-06-15. PMID:26923875. |
hippocampal metabotropic glutamate receptor long-term depression in health and disease: focus on mitogen-activated protein kinase pathways. |
2017-06-15 |
2023-08-13 |
Not clear |
| b' D Mango, E Braksator, G Battaglia, S Marcelli, N B Mercuri, M Feligioni, F Nicoletti, Z I Bashir, R Nistic\\xc3\\xb. Acid-sensing ion channel 1a is required for mGlu receptor dependent long-term depression in the hippocampus. Pharmacological research. vol 119. 2017-05-22. PMID:28137639.' |
acid-sensing ion channel 1a is required for mglu receptor dependent long-term depression in the hippocampus. |
2017-05-22 |
2023-08-13 |
Not clear |
| Lei An, Wei Su. Prenatal melamine exposure impairs spatial cognition and hippocampal synaptic plasticity by presynaptic and postsynaptic inhibition of glutamatergic transmission in adolescent offspring. Toxicology letters. vol 269. 2017-03-21. PMID:28185983. |
considering the crucial role of the other form of synaptic plasticity, long-term depression (ltd), in some types of learning and memory process, the aim of present study was to investigate if the hippocampal ltd and cognitive flexibility were affected. |
2017-03-21 |
2023-08-13 |
rat |
| Qin Li, Martin Korte, Sreedharan Sajikuma. Ubiquitin-Proteasome System Inhibition Promotes Long-Term Depression and Synaptic Tagging/Capture. Cerebral cortex (New York, N.Y. : 1991). vol 26. issue 6. 2017-03-06. PMID:25924950. |
in this study, we probed the possibility of regulating the ups by inhibiting the proteasome function during the induction of protein synthesis-independent form of hippocampal long-term depression (early-ltd), an important component of synaptic plasticity. |
2017-03-06 |
2023-08-13 |
Not clear |
| Valérie Vingtdeux, Eric H Chang, Stephen A Frattini, Haitian Zhao, Pallavi Chandakkar, Leslie Adrien, Joshua J Strohl, Elizabeth L Gibson, Makoto Ohmoto, Ichiro Matsumoto, Patricio T Huerta, Philippe Marambau. CALHM1 deficiency impairs cerebral neuron activity and memory flexibility in mice. Scientific reports. vol 6. 2017-03-01. PMID:27066908. |
however, calhm1(-/-) mice showed a severe impairment in memory flexibility, assessed in the morris water maze, and a significant disruption of long-term potentiation without alteration of long-term depression, measured in ex vivo hippocampal slices. |
2017-03-01 |
2023-08-13 |
mouse |
| Ching-Pang Chang, Cheng-Ta Lee, Wen-Hsien Hou, Meng-Syuan Lin, Hsing-Lin Lai, Chen-Li Chien, Chen Chang, Pei-Lin Cheng, Cheng-Chang Lien, Yijuang Cher. Type VI adenylyl cyclase negatively regulates GluN2B-mediated LTD and spatial reversal learning. Scientific reports. vol 6. 2017-02-17. PMID:26932446. |
consequently, glun2b-dependent calcium signaling and excitatory postsynaptic current, long-term depression, and spatial reversal learning are enhanced in the hippocampus of ac6(-/-) mice without altering the gross anatomy of the brain. |
2017-02-17 |
2023-08-13 |
mouse |
| Rebecca K Senter, Ayan Ghoshal, Adam G Walker, Zixiu Xiang, Colleen M Niswender, P Jeffrey Con. The Role of mGlu Receptors in Hippocampal Plasticity Deficits in Neurological and Psychiatric Disorders: Implications for Allosteric Modulators as Novel Therapeutic Strategies. Current neuropharmacology. vol 14. issue 5. 2017-01-17. PMID:27296640. |
long-term potentiation (ltp) and long-term depression (ltd) are two distinct forms of synaptic plasticity that have been extensively characterized at the schaffer collateral-ca1 (scca1) synapse and the mossy fiber (mf)-ca3 synapse within the hippocampus, and are postulated to be the molecular underpinning for several cognitive functions. |
2017-01-17 |
2023-08-13 |
Not clear |
| Ming-Gang Liu, Hu-Song Li, Wei-Guang Li, Yan-Jiao Wu, Shi-Ning Deng, Chen Huang, Oleksandr Maximyuk, Volodymyr Sukach, Oleg Krishtal, Michael X Zhu, Tian-Le X. Acid-sensing ion channel 1a contributes to hippocampal LTP inducibility through multiple mechanisms. Scientific reports. vol 6. 2017-01-10. PMID:26996240. |
however, these treatments did not affect hippocampal long-term depression induced by low frequency electrical stimulation or (rs)-3,5-dihydroxyphenylglycine. |
2017-01-10 |
2023-08-13 |
mouse |