| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alessandra Lintas, Ning Chi, Nicole M Lauzon, Stephanie F Bishop, Ninglei Sun, Huibing Tan, Steven R Laviolett. Inputs from the basolateral amygdala to the nucleus accumbens shell control opiate reward magnitude via differential dopamine D1 or D2 receptor transmission. The European journal of neuroscience. vol 35. issue 2. 2012-05-08. PMID:22236063. |
however, the role of da receptor signaling in the bla and its functional outputs to the nac during opiate reward processing is not currently understood. |
2012-05-08 |
2023-08-12 |
rat |
| Dave J Hayes, John Hoang, Andrew J Greensha. The role of nucleus accumbens shell GABA receptors on ventral tegmental area intracranial self-stimulation and a potential role for the 5-HT(2C) receptor. Journal of psychopharmacology (Oxford, England). vol 25. issue 12. 2012-04-26. PMID:21169393. |
these results suggest that a 5-ht(2c) and gaba(a) receptor-mediated neuronal relationship in the nac shell may be relevant for the regulation of brain reward pathways. |
2012-04-26 |
2023-08-12 |
Not clear |
| Michael D Roberts, Leigh Gilpin, Kyle E Parker, Thomas E Childs, Matthew J Will, Frank W Boot. Dopamine D1 receptor modulation in nucleus accumbens lowers voluntary wheel running in rats bred to run high distances. Physiology & behavior. vol 105. issue 3. 2012-04-16. PMID:22001493. |
dopamine signaling in the nucleus accumbens (nac) has been postulated to influence reward development towards drugs of abuse and exercise. |
2012-04-16 |
2023-08-12 |
rat |
| Michael D Roberts, Leigh Gilpin, Kyle E Parker, Thomas E Childs, Matthew J Will, Frank W Boot. Dopamine D1 receptor modulation in nucleus accumbens lowers voluntary wheel running in rats bred to run high distances. Physiology & behavior. vol 105. issue 3. 2012-04-16. PMID:22001493. |
a subset of generation 5-6 hvr and lvr rats were also used to study the mrna expression of key genes related to reward and addiction in the nac (i.e., drd1, drd5, drd2, nr4a2, fosb, and bdnf). |
2012-04-16 |
2023-08-12 |
rat |
| Jumpei Matsumoto, Susumu Urakawa, Etsuro Hori, Mariana F P de Araujo, Yasuo Sakuma, Taketoshi Ono, Hisao Nishij. Neuronal responses in the nucleus accumbens shell during sexual behavior in male rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 5. 2012-03-22. PMID:22302809. |
furthermore, nac shell neuronal activity was significantly different across the different phases of sexual behavior, and the number of nac shell neurons with delta oscillation, which is related to behavioral inhibition, and high gamma oscillation, which is related to reward perception, increased after ejaculation. |
2012-03-22 |
2023-08-12 |
rat |
| Inkyung Ahn, Jooyoung Par. Drug scheduling of cancer chemotherapy based on natural actor-critic approach. Bio Systems. vol 106. issue 2-3. 2012-02-07. PMID:21839140. |
in the framework of the nac approach, the drug dose is regarded as the control input, and the reward signal is defined as a function of the control input and the cell populations of tumor cells, normal cells, and immune cells. |
2012-02-07 |
2023-08-12 |
Not clear |
| Amy R Furay, Ross A McDevitt, Klaus A Miczek, John F Neumaie. 5-HT1B mRNA expression after chronic social stress. Behavioural brain research. vol 224. issue 2. 2011-12-21. PMID:21718722. |
the 5-ht(1b) receptor is expressed in nucleus accumbens (nac) projection neurons and modulates drug reward mechanisms and there is evidence suggesting that stress alters the regulation and function of these receptors. |
2011-12-21 |
2023-08-12 |
rat |
| Michael A McDannald, Ezequiel M Galarc. Measuring Pavlovian fear with conditioned freezing and conditioned suppression reveals different roles for the basolateral amygdala. Brain research. vol 1374. 2011-12-12. PMID:21172318. |
the nucleus accumbens core (nac), while not important to freezing, is important to the enhancement of instrumental responding by cues paired with food reward. |
2011-12-12 |
2023-08-12 |
rat |
| Amanda M Dossat, Nicole Lilly, Kristen Kay, Diana L William. Glucagon-like peptide 1 receptors in nucleus accumbens affect food intake. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 41. 2011-12-06. PMID:21994361. |
one such region is the nucleus accumbens (nac), which plays a role in reward and motivated behavior. |
2011-12-06 |
2023-08-12 |
rat |
| Amanda M Dossat, Nicole Lilly, Kristen Kay, Diana L William. Glucagon-like peptide 1 receptors in nucleus accumbens affect food intake. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 41. 2011-12-06. PMID:21994361. |
we conclude that that glp-1rs in the nac play a physiologic role in food intake control, and suggest that the glp-1 projection to nac core may link satiation signal processing in the hindbrain with forebrain processing of food reward. |
2011-12-06 |
2023-08-12 |
rat |
| Helena J V Rutherford, Sarah K Williams, Sheryl Moy, Linda C Mayes, Josephine M John. Disruption of maternal parenting circuitry by addictive process: rewiring of reward and stress systems. Frontiers in psychiatry. vol 2. 2011-11-10. PMID:21779252. |
therefore, addiction reflects the dysregulation between core reward systems, including the prefrontal cortex (pfc), ventral tegmental area (vta), and nucleus accumbens (nac), as well as the hypothalamic-pituitary-adrenal axis and extended amygdala of the stress system. |
2011-11-10 |
2023-08-12 |
human |
| Herbert E Covington, Ian Maze, HaoSheng Sun, Howard M Bomze, Kristine D DeMaio, Emma Y Wu, David M Dietz, Mary Kay Lobo, Subroto Ghose, Ezekiel Mouzon, Rachael L Neve, Carol A Tamminga, Eric J Nestle. A role for repressive histone methylation in cocaine-induced vulnerability to stress. Neuron. vol 71. issue 4. 2011-10-25. PMID:21867882. |
here, we identify repressive histone methylation in nucleus accumbens (nac), an important brain reward region, as a key mechanism linking cocaine exposure to increased stress vulnerability. |
2011-10-25 |
2023-08-12 |
mouse |
| Candice M Klingerman, Anand Patel, Valerie L Hedges, Robert L Meisel, Jill E Schneide. Food restriction dissociates sexual motivation, sexual performance, and the rewarding consequences of copulation in female Syrian hamsters. Behavioural brain research. vol 223. issue 2. 2011-10-24. PMID:21600244. |
in hamsters, formation of a conditioned place preference (cpp) for copulatory reward is reflected in increased nucleus accumbens (nac) neural activation, measured as immunocytochemical staining for c-fos, the protein product of the immediate-early gene, c-fos. |
2011-10-24 |
2023-08-12 |
Not clear |
| Xiu-Fang Lv, Ya Xu, Ji-Sheng Han, Cai-Lian Cu. Expression of activity-regulated cytoskeleton-associated protein (Arc/Arg3.1) in the nucleus accumbens is critical for the acquisition, expression and reinstatement of morphine-induced conditioned place preference. Behavioural brain research. vol 223. issue 1. 2011-10-18. PMID:21549764. |
these findings suggest that expression of the arc/arg3.1 protein in the nac core is required for the acquisition, context-induced retrieval and reinstatement of morphine-associated reward memory, whereas arc/arg3.1 protein expression in the nac shell is only critical for the context-induced retrieval of memory. |
2011-10-18 |
2023-08-12 |
rat |
| Luis Hernández, Daniel Paredes, Pedro Rad. Feeding behavior as seen through the prism of brain microdialysis. Physiology & behavior. vol 104. issue 1. 2011-10-14. PMID:21549733. |
dopamine (da) in the nucleus accumbens (nac) correlates with food reward, stimulus saliency, and goal directed hyperlocomotion but in the ventromedial hypothalamus da correlates with satiety and hypolocomotion. |
2011-10-14 |
2023-08-12 |
Not clear |
| Laura H Corbit, Bernard W Ballein. The general and outcome-specific forms of Pavlovian-instrumental transfer are differentially mediated by the nucleus accumbens core and shell. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 33. 2011-10-13. PMID:21849539. |
these results suggest that whereas the nac core mediates the general excitatory effects of reward-related cues, the nac shell mediates the effect of outcome-specific reward predictions on instrumental performance, and thereby serve to clarify reported discrepancies regarding the role of the nac core and shell in pit. |
2011-10-13 |
2023-08-12 |
rat |
| Alessandra Lintas, Ning Chi, Nicole M Lauzon, Stephanie F Bishop, Shervin Gholizadeh, Ninglei Sun, Huibing Tan, Steven R Laviolett. Identification of a dopamine receptor-mediated opiate reward memory switch in the basolateral amygdala-nucleus accumbens circuit. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 31. 2011-10-11. PMID:21813678. |
using a combination of in vivo single-unit extracellular recording in the nac combined with behavioral pharmacology studies, we have identified a double dissociation in the functional roles of da d1 versus d2 receptor transmission in the bla, which depends on opiate exposure state; thus, in previously opiate-naive rats, blockade of intra-bla d1, but not d2, receptor transmission blocked the acquisition of associative opiate reward memory, measured in an unbiased conditioned place preference procedure. |
2011-10-11 |
2023-08-12 |
rat |
| Jessy John, Rohit Manchand. Modulation of synaptic potentials and cell excitability by dendritic KIR and KAs channels in nucleus accumbens medium spiny neurons: a computational study. Journal of biosciences. vol 36. issue 2. 2011-10-07. PMID:21654085. |
the nucleus accumbens (nac), a critical structure of the brain reward circuit, is implicated in normal goal-directed behaviour and learning as well as pathological conditions like schizophrenia and addiction. |
2011-10-07 |
2023-08-12 |
Not clear |
| Segev Barak, Sebastien Carnicella, Quinn V Yowell, Dorit Ro. Glial cell line-derived neurotrophic factor reverses alcohol-induced allostasis of the mesolimbic dopaminergic system: implications for alcohol reward and seeking. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 27. 2011-09-09. PMID:21734280. |
withdrawal from excessive alcohol intake is associated with a reduction in nac da levels, whereas drug-induced increases in nac da levels are associated with reward. |
2011-09-09 |
2023-08-12 |
rat |
| Matthew B Wilkinson, Caroline Dias, Jane Magida, Michelle Mazei-Robison, MaryKay Lobo, Pamela Kennedy, David Dietz, Herbert Covington, Scott Russo, Rachael Neve, Subroto Ghose, Carol Tamminga, Eric J Nestle. A novel role of the WNT-dishevelled-GSK3β signaling cascade in the mouse nucleus accumbens in a social defeat model of depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 25. 2011-09-02. PMID:21697359. |
based on earlier gene expression and chromatin array data, we identified the protein, dishevelled (dvl)-2, as being regulated in the nucleus accumbens (nac), a key brain reward region, in the mouse social defeat model of depression. |
2011-09-02 |
2023-08-12 |
mouse |