| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wei Wang, Dalong Sun, Bin Pan, Christopher J Roberts, Xinglai Sun, Cecilia J Hillard, Qing-song Li. Deficiency in endocannabinoid signaling in the nucleus accumbens induced by chronic unpredictable stress. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 11. 2011-08-08. PMID:20664582. |
the nucleus accumbens (nac) is a critical component of the reward circuitry, and dysfunction of the nac may account for anhedonia and other symptoms of depression. |
2011-08-08 |
2023-08-12 |
mouse |
| Gabriele Hampp, Urs Albrech. The circadian clock and mood-related behavior. Communicative & integrative biology. vol 1. issue 1. 2011-07-14. PMID:19704445. |
in the mesolimbic dopaminergic reward circuit, including the ventral tegmental area (vta) and the ventral striatum/nucleus accumbens (nac) we found a positive influence of period 2 (per2) on transcriptional activation of maoa using mice mutant in the per2 gene. |
2011-07-14 |
2023-08-12 |
mouse |
| Viviana Trezza, Ruth Damsteegt, E J Marijke Achterberg, Louk J M J Vanderschure. Nucleus accumbens μ-opioid receptors mediate social reward. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 17. 2011-06-24. PMID:21525276. |
here, we studied the neural underpinnings of social reward by investigating the involvement of opioid neurotransmission in the nucleus accumbens (nac) in social play behavior, a highly rewarding social interaction in adolescent rats. |
2011-06-24 |
2023-08-12 |
rat |
| Colin M Stopper, Stan B Floresc. Contributions of the nucleus accumbens and its subregions to different aspects of risk-based decision making. Cognitive, affective & behavioral neuroscience. vol 11. issue 1. 2011-06-21. PMID:21264647. |
inactivation of the nac or the shell subregion also slightly reduced preference for larger rewards on a reward magnitude discrimination. |
2011-06-21 |
2023-08-12 |
rat |
| Jeremy J Day, Joshua L Jones, Regina M Carell. Nucleus accumbens neurons encode predicted and ongoing reward costs in rats. The European journal of neuroscience. vol 33. issue 2. 2011-06-01. PMID:21198983. |
here, neuronal activity in the rat nac was monitored using multi-neuron electrophysiology during two cost-based decision tasks in which either reward effort or reward delay was manipulated. |
2011-06-01 |
2023-08-12 |
rat |
| Barbara K A Onishi, Gilberto F Xavie. Negative anticipatory contrast: does it involve anticipation of an impending reward? Behavioural processes. vol 86. issue 2. 2011-05-27. PMID:21187128. |
the nac has been interpreted as resulting from anticipation of the impending preferred reward and its comparison with the currently available first reward [flaherty, c.f., rowan, g.a., 1985. |
2011-05-27 |
2023-08-12 |
Not clear |
| Kyohei Mori, Juhyon Kim, Kazuo Sasak. Electrophysiological effects of orexin-B and dopamine on rat nucleus accumbens shell neurons in vitro. Peptides. vol 32. issue 2. 2011-05-05. PMID:21055430. |
the mesolimbic dopamine (da) pathway that projects into the nucleus accumbens (nac) from the ventral tegmental area is deeply involved in the neural mechanisms underlying reward, drug abuse and motivation. |
2011-05-05 |
2023-08-12 |
rat |
| S L Sánchez-Serrano, S L Cruz, M Lama. Repeated toluene exposure modifies the acetylation pattern of histones H3 and H4 in the rat brain. Neuroscience letters. vol 489. issue 3. 2011-04-29. PMID:21146589. |
in order to decipher whether repeated toluene exposure could mediate epigenetic changes in the rat brain, we here analyzed the acetylation pattern of histones h3 and h4 in three brain areas that have been previously associated to substance abuse reward pathways: the nucleus accumbens (nac), the ventral tegmental area (vta) and the central amygdala (cea). |
2011-04-29 |
2023-08-12 |
rat |
| Atsumi Nitta, Yoko Hibi, Yoshiaki Miyamoto, Toshitaka Nabeshim. [Identification of Piccolo as a regulator of behavioral plasticity and dopamine transporter internalization]. Nihon Arukoru Yakubutsu Igakkai zasshi = Japanese journal of alcohol studies & drug dependence. vol 45. issue 6. 2011-04-26. PMID:21387608. |
piccolo downexpression by antisense technique augmented meth-induced behavioral sensitization, conditioned reward and synaptic dopamine accumulation in nac. |
2011-04-26 |
2023-08-12 |
mouse |
| E C Muly, M Maddox, Z U Kha. Distribution of D1 and D5 dopamine receptors in the primate nucleus accumbens. Neuroscience. vol 169. issue 4. 2011-04-18. PMID:20600664. |
the d1 family of dopamine receptors (d1r) play a critical role in modulating reward in the nucleus accumbens (nac). |
2011-04-18 |
2023-08-12 |
Not clear |
| Ian Maze, Jian Feng, Matthew B Wilkinson, HaoSheng Sun, Li Shen, Eric J Nestle. Cocaine dynamically regulates heterochromatin and repetitive element unsilencing in nucleus accumbens. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 7. 2011-04-14. PMID:21300862. |
here, we report that cocaine dramatically and dynamically alters heterochromatic histone h3 lysine 9 trimethylation (h3k9me3) in the nucleus accumbens (nac), a key brain reward region. |
2011-04-14 |
2023-08-12 |
Not clear |
| Stuart L Gibb, Jerome Jeanblanc, Segev Barak, Quinn V Yowell, Rami Yaka, Dorit Ro. Lyn kinase regulates mesolimbic dopamine release: implication for alcohol reward. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 6. 2011-03-25. PMID:21307254. |
increase in da levels in the nac is closely associated with reward-related behaviors, and overexpression of ca-lyn in the vta of mice led to an attenuation of alcohol reward, measured in a conditioned place preference paradigm. |
2011-03-25 |
2023-08-12 |
mouse |
| Xiao-Qing Peng, Zheng-Xiong Xi, Xia Li, Krista Spiller, Jie Li, Lauren Chun, Kuo-Ming Wu, Mark Froimowitz, Eliot L Gardne. Is slow-onset long-acting monoamine transport blockade to cocaine as methadone is to heroin? Implication for anti-addiction medications. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 13. 2011-03-03. PMID:20827272. |
systemic administration of 31,345 produced long-lasting enhancement of electrical brain-stimulation reward (bsr) and extracellular nucleus accumbens (nac) dopamine (da). |
2011-03-03 |
2023-08-12 |
Not clear |
| Mark C Moffett, Jane Song, Michael J Kuha. CART peptide inhibits locomotor activity induced by simultaneous stimulation of D1 and D2 receptors, but not by stimulation of individual dopamine receptors. Synapse (New York, N.Y.). vol 65. issue 1. 2011-02-04. PMID:20506412. |
previously, our laboratory demonstrated that injections of cart peptide (cart 55-102) into the nucleus accumbens (nac) attenuated both cocaine- and dopamine-induced increases in locomotor activity (lma), and attenuated cocaine reward as well. |
2011-02-04 |
2023-08-12 |
rat |
| George A Rogge, Li-Ling Shen, Michael J Kuha. Chromatin immunoprecipitation assays revealed CREB and serine 133 phospho-CREB binding to the CART gene proximal promoter. Brain research. vol 1344. 2011-01-10. PMID:20451507. |
both over expression of cyclic amp response element binding protein (creb) in the nucleus accumbens (nac), and intra-accumbal injection of cocaine- and amphetamine-regulated transcript (cart) peptides, have been shown to decrease cocaine reward. |
2011-01-10 |
2023-08-12 |
rat |
| J L Jones, J J Day, R A Wheeler, R M Carell. The basolateral amygdala differentially regulates conditioned neural responses within the nucleus accumbens core and shell. Neuroscience. vol 169. issue 3. 2010-12-16. PMID:20570714. |
given the importance of the nucleus accumbens (nac) and the basolateral amygdala (bla) in associative reward processes, recent research has examined the functional importance of bla-nac interactions. |
2010-12-16 |
2023-08-12 |
Not clear |
| Vincent Vialou, Ian Maze, William Renthal, Quincey C LaPlant, Emily L Watts, Ezekiell Mouzon, Subroto Ghose, Carol A Tamminga, Eric J Nestle. Serum response factor promotes resilience to chronic social stress through the induction of DeltaFosB. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 43. 2010-11-30. PMID:20980616. |
one molecule implicated in such adaptations is Δfosb, a transcription factor that accumulates in the rodent nucleus accumbens (nac), a key brain reward region, in response to either chronic stress or repeated exposure to drugs of abuse. |
2010-11-30 |
2023-08-12 |
mouse |
| Stephanie R Ebner, Mitchell F Roitman, David N Potter, Anna B Rachlin, Elena H Chartof. Depressive-like effects of the kappa opioid receptor agonist salvinorin A are associated with decreased phasic dopamine release in the nucleus accumbens. Psychopharmacology. vol 210. issue 2. 2010-08-17. PMID:20372879. |
although kor agonists decrease dopamine in the nucleus accumbens (nac), kor modulation of phasic dopamine release in the core and shell subregions of the nac-which have distinct roles in reward processing-remains poorly understood. |
2010-08-17 |
2023-08-12 |
Not clear |
| Nesrin Filiz Basaran, R Levent Buyukuysal, William R Millington, Sinan Cavu. Glycyl-glutamine (beta-endorphin(30-31)) inhibits morphine-induced dopamine efflux in the nucleus accumbens. Naunyn-Schmiedeberg's archives of pharmacology. vol 381. issue 5. 2010-07-23. PMID:20349045. |
in this study, we tested the hypothesis that gly-gln inhibits morphine reward by blocking morphine-induced dopamine efflux in the nucleus accumbens (nac). |
2010-07-23 |
2023-08-12 |
rat |
| Joshua L Jones, Jeremy J Day, Brandon J Aragona, Robert A Wheeler, R Mark Wightman, Regina M Carell. Basolateral amygdala modulates terminal dopamine release in the nucleus accumbens and conditioned responding. Biological psychiatry. vol 67. issue 8. 2010-06-17. PMID:20044074. |
however, the role of associative neural substrates such as the basolateral amygdala (bla) in regulating phasic dopamine release in the nac, particularly during reward seeking, remains unknown. |
2010-06-17 |
2023-08-12 |
Not clear |